Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_C04
(820 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O88597|BCN1_MOUSE Beclin-1 (Coiled-coil myosin-like BCL2... 208 2e-53
sp|Q14457|BCN1_HUMAN Beclin-1 (Coiled-coil myosin-like BCL2... 206 5e-53
sp|Q9VCE1|BCN1_DROME Beclin-1-like protein (Autophagy prote... 194 2e-49
sp|P87117|YDKA_SCHPO Hypothetical protein C20G8.10c in chro... 96 2e-19
sp|Q02948|VPS30_YEAST Vacuolar protein sorting protein 30 (... 93 8e-19
sp|Q9M367|BCN1_ARATH Beclin-1-like protein 65 2e-10
sp|Q8GFE2|CPLR_DESHA Chlorophenol reductase precursor (Orth... 31 3.6
sp|Q9URW1|YI81_SCHPO Hypothetical UPF0321 protein PJ695.01c... 30 6.1
sp|Q9WVS4|MOK_MOUSE MAPK/MAK/MRK overlapping kinase (MOK pr... 30 6.1
sp|Q6PDS3|SARM1_MOUSE Sterile alpha and TIR motif containin... 30 6.1
>sp|O88597|BCN1_MOUSE Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein)
Length = 448
Score = 208 bits (529), Expect = 2e-53
Identities = 106/224 (47%), Positives = 143/224 (63%), Gaps = 4/224 (1%)
Frame = -3
Query: 785 ERKNIEYDKIVMNYNTKKQILWDLEDDIRSLNQRKKYLSFLAERLKRTNLLNVLFPIWHE 606
ER + E + Y+ K+ +L+D+++S+ + +Y ++LK+TN+LN F IWH
Sbjct: 218 ERLDQEEAQYHREYSEFKRQQLELDDELKSVENQVRYAQIQLDKLKKTNVLNATFHIWHS 277
Query: 605 DHFATINGFRIGKLPETPVEWPEINAGLGQCVLLLHNILRKMDMALENYKLVPCGNSSYI 426
F TIN FR+G+LP PVEW EINA GQ VLLLH + KM + + Y+LVP GN SY+
Sbjct: 278 GQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYL 337
Query: 425 ESLNDKKKYL-LFKTGGYRILADNKFDQALVVYLDCLRQVIVRIENHDPNFRFPYRI-FE 252
ESL DK K L L+ +GG R DNKFD A+V +LDC++Q +E + F PYR+ E
Sbjct: 338 ESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVE 397
Query: 251 KHKIDEPEGPG--YSIKLSSNSDENWTKAMKFMLINLKWVTTWM 126
K KI++ G G YSIK NS+E WTKA+KFML NLKW W+
Sbjct: 398 KGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWV 441
>sp|Q14457|BCN1_HUMAN Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein)
(Protein GT197)
Length = 450
Score = 206 bits (525), Expect = 5e-53
Identities = 105/224 (46%), Positives = 142/224 (63%), Gaps = 4/224 (1%)
Frame = -3
Query: 785 ERKNIEYDKIVMNYNTKKQILWDLEDDIRSLNQRKKYLSFLAERLKRTNLLNVLFPIWHE 606
ER + E + Y+ K+ +L+D+++S+ + +Y ++LK+TN+ N F IWH
Sbjct: 220 ERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHS 279
Query: 605 DHFATINGFRIGKLPETPVEWPEINAGLGQCVLLLHNILRKMDMALENYKLVPCGNSSYI 426
F TIN FR+G+LP PVEW EINA GQ VLLLH + KM + + Y+LVP GN SY+
Sbjct: 280 GQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYL 339
Query: 425 ESLNDKKKYL-LFKTGGYRILADNKFDQALVVYLDCLRQVIVRIENHDPNFRFPYRI-FE 252
ESL DK K L L+ +GG R DNKFD A+V +LDC++Q +E + F PYR+ E
Sbjct: 340 ESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVE 399
Query: 251 KHKIDEPEGPG--YSIKLSSNSDENWTKAMKFMLINLKWVTTWM 126
K KI++ G G YSIK NS+E WTKA+KFML NLKW W+
Sbjct: 400 KGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWV 443
>sp|Q9VCE1|BCN1_DROME Beclin-1-like protein (Autophagy protein 6-like) (APG6-like)
Length = 422
Score = 194 bits (493), Expect = 2e-49
Identities = 93/207 (44%), Positives = 127/207 (61%)
Frame = -3
Query: 746 YNTKKQILWDLEDDIRSLNQRKKYLSFLAERLKRTNLLNVLFPIWHEDHFATINGFRIGK 567
Y ++ L EDD RSL + Y ++L+ TN+ N+ F IWH HF TIN FR+G+
Sbjct: 209 YTKHRRELMLTEDDKRSLECQIAYSKQQLDKLRDTNIFNITFHIWHAGHFGTINNFRLGR 268
Query: 566 LPETPVEWPEINAGLGQCVLLLHNILRKMDMALENYKLVPCGNSSYIESLNDKKKYLLFK 387
LP V+W EINA GQ VLLL + RK+ + E Y++VP GN SY+E L + ++ L+
Sbjct: 269 LPSVSVDWSEINAAWGQTVLLLSALARKIGLTFERYRVVPFGNHSYVEVLGENRELPLYG 328
Query: 386 TGGYRILADNKFDQALVVYLDCLRQVIVRIENHDPNFRFPYRIFEKHKIDEPEGPGYSIK 207
+GG++ D KFD A+V +LDCL Q +E D F PY++ + ID G YSIK
Sbjct: 329 SGGFKFFWDTKFDAAMVAFLDCLTQFQKEVEKRDTEFLLPYKMEKGKIIDPSTGNSYSIK 388
Query: 206 LSSNSDENWTKAMKFMLINLKWVTTWM 126
+ NS+E WTKA+KFML NLKW W+
Sbjct: 389 IQFNSEEQWTKALKFMLTNLKWGLAWV 415
>sp|P87117|YDKA_SCHPO Hypothetical protein C20G8.10c in chromosome I
Length = 499
Score = 95.5 bits (236), Expect = 2e-19
Identities = 76/269 (28%), Positives = 115/269 (42%), Gaps = 49/269 (18%)
Frame = -3
Query: 785 ERKNIEYDKIVMNYNTKKQILWDLEDDIRSLNQRKKYLSFLAERLKRTNLLNVLFPIWH- 609
E+ E + N N + LE N ++ S E+L++ N+ + +F I H
Sbjct: 228 EKVYAEEQEFYNNLNQFQIKKLSLERQYDCANLEFEHNSRKLEKLQKMNVFSDIFYISHY 287
Query: 608 -----EDHFATINGFRIGKLPETPVEWPEINAGLGQCVLLLHNILRKMDMALENYKLVPC 444
E ATING R+G+LP V W EINA G VLLL + K+D +Y+L P
Sbjct: 288 SEPNGEGSIATINGLRLGRLPSQKVNWAEINAAWGMTVLLLDVLTEKLDFHSSSYQLKPF 347
Query: 443 GNSSYIESLN-------------------------------------------DKKKYLL 393
G+ S+I + K L
Sbjct: 348 GSQSFIIRFDRDPNGNQVKPTKLDFHSSSYQLKPFGSQSFIIRFDRDPNGNQVKPTKLDL 407
Query: 392 FKTGGYRILADNKFDQALVVYLDCLRQVIVRIENHDPNFRFPYRIFEKHKIDEPEGPGYS 213
F +G +I + +FDQ +V +LD L Q P+ PY I E +I G
Sbjct: 408 FSSGELKIFMNRRFDQGMVAFLDYLHQFGDFCAAKTPSAVLPYAI-ENDRIG-----GKC 461
Query: 212 IKLSSNSDENWTKAMKFMLINLKWVTTWM 126
I+L+ N DENWT+A+KF+L ++K++ ++
Sbjct: 462 IRLAFNQDENWTRALKFVLTDIKFLEAYV 490
>sp|Q02948|VPS30_YEAST Vacuolar protein sorting protein 30 (Autophagy-related protein 6)
Length = 557
Score = 93.2 bits (230), Expect = 8e-19
Identities = 76/265 (28%), Positives = 122/265 (46%), Gaps = 47/265 (17%)
Frame = -3
Query: 791 ILERKNIEYDKIVMNYNTKKQILWDLEDDIRSLNQRKKYLSFLAERLKRTNLLNVLFPIW 612
+++ NI+++K + + + ++ SLNQ ++L++ N+ N F I
Sbjct: 288 LMDLNNIQFNKNLQSLKLQYEL---------SLNQ--------LDKLRKINIFNATFKIS 330
Query: 611 HEDHFATINGFRIGKLPETPVEWPEINAGLGQCVLLLHNILRKMDMALENYKLVPCGNSS 432
H FATING R+G +PE+ V W EINA LGQ +LLL I + + + L +Y+L P G+ S
Sbjct: 331 HSGPFATINGLRLGSIPESVVPWKEINAALGQLILLLATINKNLKINLVDYELQPMGSFS 390
Query: 431 YIES-LNDKKKYLLFKT---GGYRIL---------------ADNKFDQALVVYLDCLRQV 309
I+ + + +Y T G + IL + KFD++L L+ + ++
Sbjct: 391 KIKKRMVNSVEYNNSTTNAPGDWLILPVYYDENFNLGRIFRKETKFDKSLETTLEIISEI 450
Query: 308 IVR---------------------------IENHDPNFRFPYRIFEKHKIDEPEGPGYSI 210
+ +EN PY I K KI+ G S+
Sbjct: 451 TRQLSTIASSYSSQTLTTSQDESSMNNANDVENSTSILELPY-IMNKDKIN-----GLSV 504
Query: 209 KLSSNSDE-NWTKAMKFMLINLKWV 138
KL +S WT AMKF+L N+KW+
Sbjct: 505 KLHGSSPNLEWTTAMKFLLTNVKWL 529
>sp|Q9M367|BCN1_ARATH Beclin-1-like protein
Length = 443
Score = 65.1 bits (157), Expect = 2e-10
Identities = 41/115 (35%), Positives = 56/115 (48%)
Frame = -3
Query: 659 ERLKRTNLLNVLFPIWHEDHFATINGFRIGKLPETPVEWPEINAGLGQCVLLLHNILRKM 480
E L +TN+L FPI ++ F TIN FR+G+LP VEW EINA GQ LLLH +
Sbjct: 299 ELLNKTNVLIDAFPIRNDGEFGTINNFRLGRLPAIKVEWDEINAAWGQACLLLHTMC--- 355
Query: 479 DMALENYKLVPCGNSSYIESLNDKKKYLLFKTGGYRILADNKFDQALVVYLDCLR 315
NY K F+ G + ++D+A+ +YL CL+
Sbjct: 356 -----NY-------------FRPK-----FQFGPVNLFWSTRYDKAMTLYLMCLK 387
>sp|Q8GFE2|CPLR_DESHA Chlorophenol reductase precursor (Ortho-chlorophenol reductive
dehalogenase)
Length = 327
Score = 31.2 bits (69), Expect = 3.6
Identities = 16/46 (34%), Positives = 23/46 (50%)
Frame = -3
Query: 230 EGPGYSIKLSSNSDENWTKAMKFMLINLKWVTTWMVKASFKQYCDS 93
EG Y +K S+ S + W + M F K T V+ F +YCD+
Sbjct: 217 EGDAYGMKASAVSGKEWWEQMNFYEEYFKGKTVAEVQDWFAKYCDA 262
>sp|Q9URW1|YI81_SCHPO Hypothetical UPF0321 protein PJ695.01c precursor
Length = 117
Score = 30.4 bits (67), Expect = 6.1
Identities = 16/53 (30%), Positives = 26/53 (49%)
Frame = -3
Query: 515 CVLLLHNILRKMDMALENYKLVPCGNSSYIESLNDKKKYLLFKTGGYRILADN 357
C L L IL +D+ Y +P + + + +++ +LF TG RI A N
Sbjct: 8 CCLFLKFILANVDLTFVEYAKLPSKYAELLANATNQQGVMLFSTGDIRIGAYN 60
>sp|Q9WVS4|MOK_MOUSE MAPK/MAK/MRK overlapping kinase (MOK protein kinase)
Length = 420
Score = 30.4 bits (67), Expect = 6.1
Identities = 13/27 (48%), Positives = 18/27 (66%)
Frame = +1
Query: 517 CPNPALISGHSTGVSGNLPILKPLMVA 597
C +PAL S TG +G +P+L+PL A
Sbjct: 363 CSSPALRSVLGTGANGKVPVLRPLKCA 389
>sp|Q6PDS3|SARM1_MOUSE Sterile alpha and TIR motif containing protein 1 (Tir-1 homolog)
Length = 724
Score = 30.4 bits (67), Expect = 6.1
Identities = 10/22 (45%), Positives = 16/22 (72%)
Frame = -3
Query: 140 VTTWMVKASFKQYCDSIKEQQL 75
V TW+ + F QYC++ +EQQ+
Sbjct: 417 VQTWLQQIGFSQYCENFREQQV 438
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,303,469
Number of Sequences: 369166
Number of extensions: 1963117
Number of successful extensions: 4973
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4835
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4965
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7859674995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)