Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_015_A20
(890 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UL40|ZN346_HUMAN Zinc finger protein 346 (Just another... 50 8e-06
sp|Q9R0B7|ZN346_MOUSE Zinc finger protein 346 (Just another... 47 9e-05
sp|Q5R4W8|ZN346_PONPY Zinc finger protein 346 47 9e-05
sp|Q96PM9|ZN385_HUMAN Zinc finger protein 385 (Hematopoieti... 40 0.009
sp|Q569K4|ZN533_HUMAN Zinc finger protein 533 39 0.019
sp|Q8BXJ8|ZN533_MOUSE Zinc finger protein 533 37 0.057
sp|Q95168|ZO2_CANFA Tight junction protein ZO-2 (Zonula occ... 37 0.057
sp|Q15911|ATBF1_HUMAN Alpha-fetoprotein enhancer binding pr... 37 0.057
sp|Q61329|ATBF1_MOUSE Alpha-fetoprotein enhancer binding pr... 37 0.057
sp|P10583|GLNA_AZOBR Glutamine synthetase (Glutamate--ammon... 37 0.057
>sp|Q9UL40|ZN346_HUMAN Zinc finger protein 346 (Just another zinc finger protein)
Length = 294
Score = 50.1 bits (118), Expect = 8e-06
Identities = 42/152 (27%), Positives = 62/152 (40%), Gaps = 16/152 (10%)
Frame = +2
Query: 107 CRICESPFSSKVAALQHYSGKKHKKIAENWSSYNPVKPIDTK-----DDLRCDVCRIVGE 271
C IC FSS V A HY GK H K + V+ + D C +C
Sbjct: 136 CPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALHQNREMIDPDKFCSLCHATFN 195
Query: 272 STVQMETHYAGKKH-----QLKMKAFLERVNAGAIAPPMSSRGF-CD-----FNNVEREE 418
V + HY GKKH +LK+ A R+ A+ + +G+ C N++E+ +
Sbjct: 196 DPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQ 255
Query: 419 ANPVDPTRFIQENILPKNLTGSFLNQPDPEPP 514
A+ + F +N PK + S P P
Sbjct: 256 AH---VSGFKHKNQSPKTVASSLGQIPMQRQP 284
Score = 46.6 bits (109), Expect = 9e-05
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 8/80 (10%)
Frame = +2
Query: 101 EFCRICESPFSSKVAALQHYSGKKHKK-------IAENWSSYNP-VKPIDTKDDLRCDVC 256
+FC +C + F+ V A QHY GKKH+K +A +P V C C
Sbjct: 185 KFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYPCKTC 244
Query: 257 RIVGESTVQMETHYAGKKHQ 316
+IV S Q + H +G KH+
Sbjct: 245 KIVLNSIEQYQAHVSGFKHK 264
Score = 37.4 bits (85), Expect = 0.057
Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 17/99 (17%)
Frame = +2
Query: 107 CRICESPFSSKVAALQHYSGKKHKKIAENWSSYNPVKPID--------------TKDDLR 244
C++C + S+ L HY KKH + + + + ++ + +KD +
Sbjct: 75 CKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQ 134
Query: 245 -CDVCRIVGESTVQMETHYAGKKH--QLKMKAFLERVNA 352
C +C + S V ++HY GK H LK+K +V A
Sbjct: 135 CCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEA 173
>sp|Q9R0B7|ZN346_MOUSE Zinc finger protein 346 (Just another zinc finger protein)
Length = 294
Score = 46.6 bits (109), Expect = 9e-05
Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 8/80 (10%)
Frame = +2
Query: 101 EFCRICESPFSSKVAALQHYSGKKHKK-------IAENWSSYNP-VKPIDTKDDLRCDVC 256
+FC +C S F+ A QHY GK+H+K +A +P V + C C
Sbjct: 185 KFCSLCHSTFNDPAMAQQHYMGKRHRKQETKLKLMAHYGRLADPAVSDLPAGKGYPCKTC 244
Query: 257 RIVGESTVQMETHYAGKKHQ 316
+IV S Q + H +G KH+
Sbjct: 245 KIVLNSIEQYQAHVSGFKHK 264
Score = 43.9 bits (102), Expect = 6e-04
Identities = 44/170 (25%), Positives = 66/170 (38%), Gaps = 35/170 (20%)
Frame = +2
Query: 71 INEDVHRLDLE-----------FCRICESPFSSKVAALQHYSGKKHKK------------ 181
I DV RLD + C IC FSS A HY GK H K
Sbjct: 113 IKGDVKRLDSDQKSSRSKDKNHCCPICNMTFSSPAVAQSHYLGKTHAKSLKLKQQSTKGA 172
Query: 182 -IAENWSSYNPVKPIDTKDDLRCDVCRIVGESTVQMETHYAGKKH-----QLKMKAFLER 343
+ +N +P D C +C + HY GK+H +LK+ A R
Sbjct: 173 ALQQNREMLDP--------DKFCSLCHSTFNDPAMAQQHYMGKRHRKQETKLKLMAHYGR 224
Query: 344 VNAGAIAPPMSSRGF-CD-----FNNVEREEANPVDPTRFIQENILPKNL 475
+ A++ + +G+ C N++E+ +A+ + F +N PK L
Sbjct: 225 LADPAVSDLPAGKGYPCKTCKIVLNSIEQYQAH---VSGFKHKNQSPKTL 271
Score = 37.0 bits (84), Expect = 0.074
Identities = 22/102 (21%), Positives = 41/102 (40%), Gaps = 17/102 (16%)
Frame = +2
Query: 107 CRICESPFSSKVAALQHYSGKKHKKIAENWSSYNPVKPIDTKDDLR-------------- 244
C++C + S+ L HY KKH + + + + ++ I K D++
Sbjct: 75 CKVCCAMLISESQKLAHYQSKKHANKVKRYLAIHGMETI--KGDVKRLDSDQKSSRSKDK 132
Query: 245 ---CDVCRIVGESTVQMETHYAGKKHQLKMKAFLERVNAGAI 361
C +C + S ++HY GK H +K + A+
Sbjct: 133 NHCCPICNMTFSSPAVAQSHYLGKTHAKSLKLKQQSTKGAAL 174
>sp|Q5R4W8|ZN346_PONPY Zinc finger protein 346
Length = 310
Score = 46.6 bits (109), Expect = 9e-05
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 8/80 (10%)
Frame = +2
Query: 101 EFCRICESPFSSKVAALQHYSGKKHKK-------IAENWSSYNP-VKPIDTKDDLRCDVC 256
+FC +C + F+ V A QHY GKKH+K +A +P V C C
Sbjct: 201 KFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYPCKTC 260
Query: 257 RIVGESTVQMETHYAGKKHQ 316
+IV S Q + H +G KH+
Sbjct: 261 KIVLNSIEQYQAHVSGFKHK 280
Score = 45.1 bits (105), Expect = 3e-04
Identities = 44/170 (25%), Positives = 65/170 (38%), Gaps = 34/170 (20%)
Frame = +2
Query: 107 CRICESPFSSKVAALQHYSGKKHKK-----------------------IAENWSSYNPVK 217
C IC FSS V A HY GK H K +A + + +
Sbjct: 136 CPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALSKRLTNPFLVASTLALHQNRE 195
Query: 218 PIDTKDDLRCDVCRIVGESTVQMETHYAGKKH-----QLKMKAFLERVNAGAIAPPMSSR 382
ID D C +C V + HY GKKH +LK+ A R+ A+ + +
Sbjct: 196 MID--PDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGK 253
Query: 383 GF-CD-----FNNVEREEANPVDPTRFIQENILPKNLTGSFLNQPDPEPP 514
G+ C N++E+ +A+ + F +N PK + S P P
Sbjct: 254 GYPCKTCKIVLNSIEQYQAH---VSGFKHKNQSPKTVASSLGQIPMQRQP 300
Score = 39.3 bits (90), Expect = 0.015
Identities = 25/128 (19%), Positives = 52/128 (40%), Gaps = 15/128 (11%)
Frame = +2
Query: 107 CRICESPFSSKVAALQHYSGKKHKKIAENWSSYNPVKPID--------------TKDDLR 244
C++C + S+ L HY KKH + + + + ++ + +KD +
Sbjct: 75 CKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQ 134
Query: 245 -CDVCRIVGESTVQMETHYAGKKHQLKMKAFLERVNAGAIAPPMSSRGFCDFNNVEREEA 421
C +C + S V ++HY GK H +K + A++ +++ +
Sbjct: 135 CCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALSKRLTNPFLVASTLALHQNR 194
Query: 422 NPVDPTRF 445
+DP +F
Sbjct: 195 EMIDPDKF 202
>sp|Q96PM9|ZN385_HUMAN Zinc finger protein 385 (Hematopoietic zinc finger protein)
(Retinal zinc finger protein)
Length = 366
Score = 40.0 bits (92), Expect = 0.009
Identities = 37/148 (25%), Positives = 54/148 (36%), Gaps = 14/148 (9%)
Frame = +2
Query: 98 LEFCRICESPFSSKVAALQHYSGKKHKKIAENWSSYNPVK------------PIDTKDD- 238
L +C +C+ +S H G KHK I E S P+K P D
Sbjct: 180 LLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDR 239
Query: 239 -LRCDVCRIVGESTVQMETHYAGKKHQLKMKAFLERVNAGAIAPPMSSRGFCDFNNVERE 415
C++C + S VQ++ H + ++H R P+ SR + R
Sbjct: 240 TFHCEICNVKVNSEVQLKQHISSRRH---------RDGVAGKPNPLLSR-----HKKSRG 285
Query: 416 EANPVDPTRFIQENILPKNLTGSFLNQP 499
F +E LPK+L G L P
Sbjct: 286 AGELAGTLTFSKE--LPKSLAGGLLPSP 311
Score = 30.4 bits (67), Expect = 6.9
Identities = 11/30 (36%), Positives = 18/30 (60%)
Frame = +2
Query: 239 LRCDVCRIVGESTVQMETHYAGKKHQLKMK 328
+ C++C+I S Q E HY G +H ++K
Sbjct: 54 ISCNICQIRFNSQSQAEAHYKGNRHARRVK 83
>sp|Q569K4|ZN533_HUMAN Zinc finger protein 533
Length = 471
Score = 38.9 bits (89), Expect = 0.019
Identities = 36/180 (20%), Positives = 73/180 (40%), Gaps = 17/180 (9%)
Frame = +2
Query: 11 STAPTKSSKVPFRELVKKFEINEDVHRLDLEFCRICESPFSSKVAALQHYSGKKHKKIAE 190
+T+P+KS+ +V+ +E+ L +C +C+ +S H +G KHK + E
Sbjct: 259 ATSPSKSTNGAPGTVVE----SEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVE 314
Query: 191 NWSSYNPVKPID-----------------TKDDLRCDVCRIVGESTVQMETHYAGKKHQL 319
+ P+K C++C + S +Q++ H + ++H+
Sbjct: 315 ARNGAGPIKSYPRPGSRLKMQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHK- 373
Query: 320 KMKAFLERVNAGAIAPPMSSRGFCDFNNVEREEANPVDPTRFIQENILPKNLTGSFLNQP 499
+RV + P S +N ++R + F ++ + P L +FL+ P
Sbjct: 374 ------DRVAGKPLKPKYS-----PYNKLQRSPSILAAKLAFQKDMMKP--LAPAFLSSP 420
Score = 37.0 bits (84), Expect = 0.074
Identities = 19/54 (35%), Positives = 25/54 (46%)
Frame = +2
Query: 218 PIDTKDDLRCDVCRIVGESTVQMETHYAGKKHQLKMKAFLERVNAGAIAPPMSS 379
P K + C+VC++ S Q E HY G KH K+KA N + P S
Sbjct: 150 PPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALDATKNKPKMVPSKDS 203
Score = 35.8 bits (81), Expect = 0.16
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Frame = +2
Query: 107 CRICESPFSSKVAALQHYSGKKH-KKIAENWSSYNPVKPIDTKDDLR----CDVCRIVGE 271
C +C+ F+S A HY G KH KK+ ++ N K + +KD + C + I G
Sbjct: 159 CNVCQLRFNSDSQAEAHYKGSKHAKKVKALDATKNKPKMVPSKDSAKANPSCSITPITGN 218
Query: 272 STVQME 289
++ + E
Sbjct: 219 NSDKSE 224
Score = 32.7 bits (73), Expect = 1.4
Identities = 13/51 (25%), Positives = 25/51 (49%)
Frame = +2
Query: 68 EINEDVHRLDLEFCRICESPFSSKVAALQHYSGKKHKKIAENWSSYNPVKP 220
+++++ ++ FC +C +S A H +GK H+K + S P P
Sbjct: 23 QLSKEKKKILFSFCEVCNIQLNSAAQAQVHSNGKSHRKRVKQLSDGQPPPP 73
>sp|Q8BXJ8|ZN533_MOUSE Zinc finger protein 533
Length = 482
Score = 37.4 bits (85), Expect = 0.057
Identities = 17/67 (25%), Positives = 28/67 (41%)
Frame = +2
Query: 68 EINEDVHRLDLEFCRICESPFSSKVAALQHYSGKKHKKIAENWSSYNPVKPIDTKDDLRC 247
+ +++ ++ FC +C +S A HY GK H+K + S P P+ L
Sbjct: 23 QFSKEKKKILFSFCEVCNIQLNSAAQAQVHYDGKSHRKRVKQLSDGQPPPPVQGSVPLLA 82
Query: 248 DVCRIVG 268
C G
Sbjct: 83 GPCPCPG 89
Score = 37.4 bits (85), Expect = 0.057
Identities = 19/54 (35%), Positives = 25/54 (46%)
Frame = +2
Query: 218 PIDTKDDLRCDVCRIVGESTVQMETHYAGKKHQLKMKAFLERVNAGAIAPPMSS 379
P K + C+VC++ S Q E HY G KH K+KA N + P S
Sbjct: 162 PPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKMVPSKDS 215
Score = 37.4 bits (85), Expect = 0.057
Identities = 31/159 (19%), Positives = 62/159 (38%), Gaps = 17/159 (10%)
Frame = +2
Query: 74 NEDVHRLDLEFCRICESPFSSKVAALQHYSGKKHKKIAENWSSYNPVKPIDTKDD----- 238
+E+ L +C +C+ +S H +G KHK + E + P+K
Sbjct: 288 SEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQ 347
Query: 239 ------------LRCDVCRIVGESTVQMETHYAGKKHQLKMKAFLERVNAGAIAPPMSSR 382
C++C + S +Q++ H + ++H+ +RV + P S
Sbjct: 348 NGSKGSGLQNKMFHCEICDVHVNSEIQLKQHISSRRHK-------DRVAGKPLKPKYS-- 398
Query: 383 GFCDFNNVEREEANPVDPTRFIQENILPKNLTGSFLNQP 499
+N ++R + + + + L K L +FL+ P
Sbjct: 399 ---PYNKLQRSPS--ILAAKLAFQKDLMKPLAPTFLSSP 432
Score = 34.3 bits (77), Expect = 0.48
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Frame = +2
Query: 107 CRICESPFSSKVAALQHYSGKKH-KKIAENWSSYNPVKPIDTKDDLR----CDVCRIVGE 271
C +C+ F+S A HY G KH KK+ ++ N K + +KD + C + G+
Sbjct: 171 CNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKMVPSKDSAKANPSCSIRPGTGD 230
Query: 272 STVQME 289
S+ + E
Sbjct: 231 SSDKSE 236
Score = 32.7 bits (73), Expect = 1.4
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = +2
Query: 245 CDVCRIVGESTVQMETHYAGKKHQLKMKAFLERVNAGAIAPPM 373
C+VC I S Q + HY GK H+ ++K +++ G PP+
Sbjct: 36 CEVCNIQLNSAAQAQVHYDGKSHRKRVK----QLSDGQPPPPV 74
>sp|Q95168|ZO2_CANFA Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona
occludens 2 protein) (Tight junction protein 2)
Length = 1174
Score = 37.4 bits (85), Expect = 0.057
Identities = 28/100 (28%), Positives = 42/100 (42%)
Frame = +2
Query: 539 DEDYGIRRTINTGFDSDYGMRSSAGYDNDYGMPRSSGLGMDSDYGMPRTVNPGFDSDYLM 718
D+DY R + G + G+ +D+DYG P GM +D G R + G+D Y
Sbjct: 181 DDDYRRpreRSRGRSLERGL----DHDDDYGRPGERSHGMSTDRGYDRGYDRGYDRGY-- 234
Query: 719 PRQNKPLFEPDFTNDIKPDIKRGFGGMPEDSLLDNRMPPP 838
R P E ++ +PD + L +R P P
Sbjct: 235 DRTYSP--EAEYGRRTQPDARHAGSRSRSREHLRSRSPSP 272
>sp|Q15911|ATBF1_HUMAN Alpha-fetoprotein enhancer binding protein (AT motif-binding factor)
(AT-binding transcription factor 1)
Length = 3703
Score = 37.4 bits (85), Expect = 0.057
Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 5/80 (6%)
Frame = +2
Query: 107 CRICESPFSSKVAALQHYSGKKH---KKIAENWSSYNPVKPIDTKDD--LRCDVCRIVGE 271
C +C+ F+ K L HY+ H K A S+ +P + D+ +C+ C +
Sbjct: 1547 CTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNVAYS 1606
Query: 272 STVQMETHYAGKKHQLKMKA 331
+ +E H HQ K +A
Sbjct: 1607 QSSTLEIHMRSVLHQTKARA 1626
>sp|Q61329|ATBF1_MOUSE Alpha-fetoprotein enhancer binding protein (AT motif-binding factor)
(AT-binding transcription factor 1)
Length = 3726
Score = 37.4 bits (85), Expect = 0.057
Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 5/80 (6%)
Frame = +2
Query: 107 CRICESPFSSKVAALQHYSGKKH---KKIAENWSSYNPVKPIDTKDD--LRCDVCRIVGE 271
C +C+ F+ K L HY+ H K A S+ +P + D+ +C+ C +
Sbjct: 1557 CTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNVAYS 1616
Query: 272 STVQMETHYAGKKHQLKMKA 331
+ +E H HQ K +A
Sbjct: 1617 QSSTLEIHMRSVLHQTKARA 1636
Score = 31.2 bits (69), Expect = 4.1
Identities = 18/65 (27%), Positives = 26/65 (40%)
Frame = +2
Query: 131 SSKVAALQHYSGKKHKKIAENWSSYNPVKPIDTKDDLRCDVCRIVGESTVQMETHYAGKK 310
S+ AA + I +W + +P KP TK RC+VC + H +K
Sbjct: 770 SAGAAAAAAAAAAAAANIGSSWGAPSPTKP-KTKPTWRCEVCDYETNVARNLRIHMTSEK 828
Query: 311 HQLKM 325
H M
Sbjct: 829 HMHNM 833
>sp|P10583|GLNA_AZOBR Glutamine synthetase (Glutamate--ammonia ligase)
Length = 468
Score = 37.4 bits (85), Expect = 0.057
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 7/102 (6%)
Frame = +2
Query: 44 FRELVKKFEINEDVHRLDLEFCRICESPFSS----KVAALQHYSGKKHKKIAENWSSYNP 211
F ++ K E+N+ + D E E P++S + L H G K Y P
Sbjct: 137 FDDVKFKVEMNKVSYEFDSE-----EGPYTSDKDYEDGNLGHRPGVK--------GGYFP 183
Query: 212 VKPIDTKDDLRCDVCRIVGESTVQMETHY---AGKKHQLKMK 328
V P+D+ DLR ++ ++ E V +E H+ A +H+L +K
Sbjct: 184 VAPVDSGSDLRAEMLSVLAEMGVPVEKHHHEVAASQHELGIK 225
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 113,677,959
Number of Sequences: 369166
Number of extensions: 2555335
Number of successful extensions: 7505
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6734
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7430
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8934348180
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)