Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_014_P19 (206 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P07858|CATB_HUMAN Cathepsin B precursor (Cathepsin B1) (... 100 2e-21 sp|P07688|CATB_BOVIN Cathepsin B precursor [Contains: Cathe... 96 3e-20 sp|P00787|CATB_RAT Cathepsin B precursor (Cathepsin B1) (RS... 95 6e-20 sp|P10605|CATB_MOUSE Cathepsin B precursor (Cathepsin B1) [... 93 2e-19 sp|P43233|CATB_CHICK Cathepsin B precursor (Cathepsin B1) [... 92 3e-19 sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4... 92 3e-19 sp|P25792|CYSP_SCHMA Cathepsin B-like cysteine proteinase p... 90 1e-18 sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5... 90 1e-18 sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6... 86 3e-17 sp|P43157|CYSP_SCHJA Cathepsin B-like cysteine proteinase p... 82 4e-16
>sp|P07858|CATB_HUMAN Cathepsin B precursor (Cathepsin B1) (APP secretase) (APPS) [Contains: Cathepsin B light chain; Cathepsin B heavy chain] Length = 339 Score = 99.8 bits (247), Expect = 2e-21 Identities = 42/50 (84%), Positives = 44/50 (88%) Frame = +2 Query: 2 ILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDECGIEDEVVAGIPK 151 ILGWGVEN TPYWLVANSWN WGDNG+FKILRG D CGIE EVVAGIP+ Sbjct: 282 ILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
>sp|P07688|CATB_BOVIN Cathepsin B precursor [Contains: Cathepsin B light chain; Cathepsin B heavy chain] Length = 335 Score = 95.9 bits (237), Expect = 3e-20 Identities = 39/49 (79%), Positives = 42/49 (85%) Frame = +2 Query: 2 ILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDECGIEDEVVAGIP 148 ILGWGVEN TPYWLV NSWN WGDNG+FKILRG D CGIE E+VAG+P Sbjct: 282 ILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGMP 330
>sp|P00787|CATB_RAT Cathepsin B precursor (Cathepsin B1) (RSG-2) [Contains: Cathepsin B light chain; Cathepsin B heavy chain] Length = 339 Score = 94.7 bits (234), Expect = 6e-20 Identities = 38/50 (76%), Positives = 43/50 (86%) Frame = +2 Query: 2 ILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDECGIEDEVVAGIPK 151 ILGWG+EN PYWLVANSWN WGDNG+FKILRG + CGIE E+VAGIP+ Sbjct: 282 ILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHCGIESEIVAGIPR 331
>sp|P10605|CATB_MOUSE Cathepsin B precursor (Cathepsin B1) [Contains: Cathepsin B light chain; Cathepsin B heavy chain] Length = 339 Score = 93.2 bits (230), Expect = 2e-19 Identities = 38/50 (76%), Positives = 42/50 (84%) Frame = +2 Query: 2 ILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDECGIEDEVVAGIPK 151 ILGWGVEN PYWL ANSWN WGDNG+FKILRG + CGIE E+VAGIP+ Sbjct: 282 ILGWGVENGVPYWLAANSWNLDWGDNGFFKILRGENHCGIESEIVAGIPR 331
>sp|P43233|CATB_CHICK Cathepsin B precursor (Cathepsin B1) [Contains: Cathepsin B light chain; Cathepsin B heavy chain] Length = 340 Score = 92.4 bits (228), Expect = 3e-19 Identities = 37/51 (72%), Positives = 42/51 (82%) Frame = +2 Query: 2 ILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDECGIEDEVVAGIPKL 154 ILGWGVEN TPYWL ANSWN WG G+FKILRG D CGIE E+VAG+P++ Sbjct: 283 ILGWGVENGTPYWLAANSWNTDWGITGFFKILRGEDHCGIESEIVAGVPRM 333
>sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4 precursor (Cysteine protease-related 4) Length = 335 Score = 92.4 bits (228), Expect = 3e-19 Identities = 36/51 (70%), Positives = 44/51 (86%) Frame = +2 Query: 2 ILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDECGIEDEVVAGIPKL 154 ILGWG +N TPYWLVANSWN WG+NGYF+I+RG++ECGIE VV G+PK+ Sbjct: 285 ILGWGTDNGTPYWLVANSWNVNWGENGYFRIIRGTNECGIEHAVVGGVPKV 335
>sp|P25792|CYSP_SCHMA Cathepsin B-like cysteine proteinase precursor (Antigen Sm31) Length = 340 Score = 90.1 bits (222), Expect = 1e-18 Identities = 35/47 (74%), Positives = 41/47 (87%) Frame = +2 Query: 2 ILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDECGIEDEVVAG 142 I+GWGVEN TPYWL+ANSWN WG+NGYF+I+RG DEC IE EV+AG Sbjct: 291 IIGWGVENKTPYWLIANSWNEDWGENGYFRIVRGRDECSIESEVIAG 337
>sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5 precursor (Cysteine protease-related 5) Length = 344 Score = 90.1 bits (222), Expect = 1e-18 Identities = 37/51 (72%), Positives = 42/51 (82%) Frame = +2 Query: 2 ILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDECGIEDEVVAGIPKL 154 ILGWGV+N TPYWLVANSWN WG+ GYF+I+RG +ECGIE VAGIP L Sbjct: 290 ILGWGVDNGTPYWLVANSWNVAWGEKGYFRIIRGLNECGIEHSAVAGIPDL 340
>sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6 precursor (Cysteine protease-related 6) Length = 379 Score = 85.5 bits (210), Expect = 3e-17 Identities = 33/51 (64%), Positives = 42/51 (82%) Frame = +2 Query: 2 ILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDECGIEDEVVAGIPKL 154 ++GWG+++ PYW VANSWN WG++G+F+ILRG DECGIE VV GIPKL Sbjct: 309 LIGWGIDDGIPYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKL 359
>sp|P43157|CYSP_SCHJA Cathepsin B-like cysteine proteinase precursor (Antigen Sj31) Length = 342 Score = 82.0 bits (201), Expect = 4e-16 Identities = 32/50 (64%), Positives = 40/50 (80%) Frame = +2 Query: 2 ILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDECGIEDEVVAGIPK 151 I+GWGVE TPYWL+ANSWN WG+ G F+++RG DEC IE +VVAG+ K Sbjct: 292 IIGWGVEKRTPYWLIANSWNEDWGEKGLFRMVRGRDECSIESDVVAGLIK 341
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,397,766 Number of Sequences: 369166 Number of extensions: 396605 Number of successful extensions: 1257 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1247 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1257 length of database: 68,354,980 effective HSP length: 40 effective length of database: 60,965,580 effective search space used: 1707036240 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)