Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_P12
(529 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P56560|AOFB_BOVIN Amine oxidase [flavin-containing] B (M... 74 2e-13
sp|Q7YRB7|AOFB_CANFA Amine oxidase [flavin-containing] B (M... 74 3e-13
sp|P49253|AOF_ONCMY Amine oxidase [flavin-containing] (Mono... 73 4e-13
sp|P27338|AOFB_HUMAN Amine oxidase [flavin-containing] B (M... 73 5e-13
sp|Q5RE98|AOFB_PONPY Amine oxidase [flavin-containing] B (M... 73 5e-13
sp|P58028|AOFB_CAVPO Amine oxidase [flavin-containing] B (M... 70 3e-12
sp|Q6PLK3|AOFB_PIG Amine oxidase [flavin-containing] B (Mon... 69 5e-12
sp|Q64133|AOFA_MOUSE Amine oxidase [flavin-containing] A (M... 68 2e-11
sp|P21396|AOFA_RAT Amine oxidase [flavin-containing] A (Mon... 67 3e-11
sp|Q8BW75|AOFB_MOUSE Amine oxidase [flavin-containing] B (M... 67 3e-11
>sp|P56560|AOFB_BOVIN Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 73.9 bits (180), Expect = 2e-13
Identities = 48/167 (28%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
Frame = +3
Query: 6 FANSCGGFHNFLESGEGTAHGYKIVGGAARILSTILEVIGSDTIDIHTVVSSISKKDTHS 185
+ CGG + G K VGG+ ++ I++++G D + + V I + +
Sbjct: 188 YVKQCGGTTRIFSTSNG-GQERKFVGGSGQVSERIMDLLG-DRVKLERPVIHIDQTGENV 245
Query: 186 EIHTVSGTTYKAKHVILTVPPHLMLNIQFDPPLNPTKIEYFSSVIPGHVIKVILTYETRF 365
+ T++ Y+AK+VI VPP L + I F+PPL + + + V G VIK I+ Y+ F
Sbjct: 246 LVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLTTRVPLGSVIKSIVYYKEPF 305
Query: 366 WMSGGYSGEIVSNGGPSFIDGCSTGPLCVVFDATTENNS-PALVCFI 503
W + Y G ++ G P+ D T + S PA++ FI
Sbjct: 306 WRNMDYCGSMIIEG--------EEAPVAYALDDTKPDGSYPAIIGFI 344
>sp|Q7YRB7|AOFB_CANFA Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 73.6 bits (179), Expect = 3e-13
Identities = 46/167 (27%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
Frame = +3
Query: 6 FANSCGGFHNFLESGEGTAHGYKIVGGAARILSTILEVIGSDTIDIHTVVSSISKKDTHS 185
+ CGG + + G K VGG+ ++ I++++G D + + V+ I + +
Sbjct: 188 YVKQCGGTTRIISTTNG-GQERKFVGGSGQVSERIMDLLG-DQVKLERPVTHIDQTGENV 245
Query: 186 EIHTVSGTTYKAKHVILTVPPHLMLNIQFDPPLNPTKIEYFSSVIPGHVIKVILTYETRF 365
+ T++ Y+AK+VI +PP L + I F+PPL + + + V G VIK I+ Y+ F
Sbjct: 246 LVETLNHEVYEAKYVISAIPPTLGMKIHFNPPLPMMRNQLITRVPLGSVIKCIVYYKEPF 305
Query: 366 WMSGGYSGEIVSNGGPSFIDGCSTGPLCVVFDAT-TENNSPALVCFI 503
W Y G ++ G P+ D T + N A++ FI
Sbjct: 306 WRKKDYCGTMIIEG--------EEAPIAYTLDDTKPDGNYAAIMGFI 344
>sp|P49253|AOF_ONCMY Amine oxidase [flavin-containing] (Monoamine oxidase) (MAO)
Length = 522
Score = 73.2 bits (178), Expect = 4e-13
Identities = 48/167 (28%), Positives = 79/167 (47%), Gaps = 1/167 (0%)
Frame = +3
Query: 6 FANSCGGFHNFLESGEGTAHGYKIVGGAARILSTILEVIGSDTIDIHTVVSSISKKDTHS 185
+ CGG + G K +GG+++I + + +G + + + + V I +
Sbjct: 190 YVKQCGGTMRIFSTTNG-GQERKFLGGSSQISECMAKELG-ERVKMESPVYKIDQTGDMV 247
Query: 186 EIHTVSGTTYKAKHVILTVPPHLMLNIQFDPPLNPTKIEYFSSVIPGHVIKVILTYETRF 365
E+ T++ TYKAK+VI+ PP L L + F+P L P + + V G VIK I+ Y F
Sbjct: 248 EVETLNKETYKAKYVIVATPPGLNLKMHFNPELPPLRNQLIHRVPMGSVIKCIVYYRENF 307
Query: 366 WMSGGYSGEIVSNGGPSFIDGCSTGPLCVVFDATTENNS-PALVCFI 503
W GY G +V P+ + D T + + PA++ FI
Sbjct: 308 WRKKGYCGTMVIEE--------EEAPIGLTLDDTKPDGTVPAIMGFI 346
>sp|P27338|AOFB_HUMAN Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 72.8 bits (177), Expect = 5e-13
Identities = 47/166 (28%), Positives = 79/166 (47%)
Frame = +3
Query: 6 FANSCGGFHNFLESGEGTAHGYKIVGGAARILSTILEVIGSDTIDIHTVVSSISKKDTHS 185
+ CGG + + G K VGG+ ++ I++++G D + + V I + +
Sbjct: 188 YVKQCGGTTRIISTTNG-GQERKFVGGSGQVSERIMDLLG-DRVKLERPVIYIDQTRENV 245
Query: 186 EIHTVSGTTYKAKHVILTVPPHLMLNIQFDPPLNPTKIEYFSSVIPGHVIKVILTYETRF 365
+ T++ Y+AK+VI +PP L + I F+PPL + + + V G VIK I+ Y+ F
Sbjct: 246 LVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPF 305
Query: 366 WMSGGYSGEIVSNGGPSFIDGCSTGPLCVVFDATTENNSPALVCFI 503
W Y G ++ IDG + D E N A++ FI
Sbjct: 306 WRKKDYCGTMI-------IDGEEAPVAYTLDDTKPEGNYAAIMGFI 344
>sp|Q5RE98|AOFB_PONPY Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 72.8 bits (177), Expect = 5e-13
Identities = 47/166 (28%), Positives = 79/166 (47%)
Frame = +3
Query: 6 FANSCGGFHNFLESGEGTAHGYKIVGGAARILSTILEVIGSDTIDIHTVVSSISKKDTHS 185
+ CGG + + G K VGG+ ++ I++++G D + + V I + +
Sbjct: 188 YVKQCGGTTRIISTTNG-GQERKFVGGSGQVSERIMDLLG-DRVKLERPVIYIDQTRENV 245
Query: 186 EIHTVSGTTYKAKHVILTVPPHLMLNIQFDPPLNPTKIEYFSSVIPGHVIKVILTYETRF 365
+ T++ Y+AK+VI +PP L + I F+PPL + + + V G VIK I+ Y+ F
Sbjct: 246 LVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPF 305
Query: 366 WMSGGYSGEIVSNGGPSFIDGCSTGPLCVVFDATTENNSPALVCFI 503
W Y G ++ IDG + D E N A++ FI
Sbjct: 306 WRKKDYCGTMI-------IDGEEAPVAYTLDDTKPEGNYAAIMGFI 344
>sp|P58028|AOFB_CAVPO Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 70.1 bits (170), Expect = 3e-12
Identities = 48/166 (28%), Positives = 77/166 (46%)
Frame = +3
Query: 6 FANSCGGFHNFLESGEGTAHGYKIVGGAARILSTILEVIGSDTIDIHTVVSSISKKDTHS 185
+ CGG + + G K VGG+ +I I+ ++G D + + V I +
Sbjct: 188 YVKQCGGTTRIISTTNG-GQERKFVGGSGQISERIMNLLG-DRVKLQRPVVYIDQTGESV 245
Query: 186 EIHTVSGTTYKAKHVILTVPPHLMLNIQFDPPLNPTKIEYFSSVIPGHVIKVILTYETRF 365
+ T++ Y+AK+VI +PP L + I F PPL K + S V G VIK I+ Y+ F
Sbjct: 246 LVETLNHEIYEAKYVISAIPPALGMKIHFKPPLPMMKNQLVSRVPLGSVIKCIVYYKDPF 305
Query: 366 WMSGGYSGEIVSNGGPSFIDGCSTGPLCVVFDATTENNSPALVCFI 503
W + G +V I+G L + D + + A++ FI
Sbjct: 306 WRKKDFCGTMV-------IEGEEAPVLYTMDDTKPDGSYAAIIGFI 344
>sp|Q6PLK3|AOFB_PIG Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 69.3 bits (168), Expect = 5e-12
Identities = 39/134 (29%), Positives = 66/134 (49%)
Frame = +3
Query: 6 FANSCGGFHNFLESGEGTAHGYKIVGGAARILSTILEVIGSDTIDIHTVVSSISKKDTHS 185
+ CGG + + G K VGG+ ++ I +++G D + + V I + +
Sbjct: 188 YVKQCGGTTRIISTTNG-GQERKFVGGSGQVTERIKDLLG-DRVKLERPVVHIDQTGENV 245
Query: 186 EIHTVSGTTYKAKHVILTVPPHLMLNIQFDPPLNPTKIEYFSSVIPGHVIKVILTYETRF 365
+ T++ Y+AK+VI +PP L + I F PPL + + + V G VIK I+ Y+ F
Sbjct: 246 LVETLNHEVYEAKYVISAIPPVLGMKIHFSPPLPMMRNQLITRVPLGSVIKCIVYYKEPF 305
Query: 366 WMSGGYSGEIVSNG 407
W Y G ++ G
Sbjct: 306 WRHKDYCGSMIIEG 319
>sp|Q64133|AOFA_MOUSE Amine oxidase [flavin-containing] A (Monoamine oxidase type A)
(MAO-A)
Length = 526
Score = 67.8 bits (164), Expect = 2e-11
Identities = 46/167 (27%), Positives = 76/167 (45%), Gaps = 1/167 (0%)
Frame = +3
Query: 6 FANSCGGFHNFLESGEGTAHGYKIVGGAARILSTILEVIGSDTIDIHTVVSSISKKDTHS 185
+ CGG G K VGG+ +I I+ ++G D + + + V+ I + D +
Sbjct: 197 YVRQCGGTSRIFSVTNG-GQERKFVGGSGQISEQIMVLLG-DKVKLSSPVTYIDQTDDNI 254
Query: 186 EIHTVSGTTYKAKHVILTVPPHLMLNIQFDPPLNPTKIEYFSSVIPGHVIKVILTYETRF 365
I T++ Y+ K+VI +PP L I F P L P + + + G VIK ++ Y+ F
Sbjct: 255 IIETLNHEHYECKYVISAIPPVLTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAF 314
Query: 366 WMSGGYSGEIVSNGGPSFIDGCSTGPLCVVFDATTENNS-PALVCFI 503
W Y G ++ P+ + D T + S PA++ FI
Sbjct: 315 WKKKDYCGCMIIED--------EEAPISITLDDTKPDGSMPAIMGFI 353
>sp|P21396|AOFA_RAT Amine oxidase [flavin-containing] A (Monoamine oxidase type A)
(MAO-A)
Length = 526
Score = 67.0 bits (162), Expect = 3e-11
Identities = 44/167 (26%), Positives = 76/167 (45%), Gaps = 1/167 (0%)
Frame = +3
Query: 6 FANSCGGFHNFLESGEGTAHGYKIVGGAARILSTILEVIGSDTIDIHTVVSSISKKDTHS 185
+ CGG G K VGG+ ++ I+ ++G D + + + V+ I + D +
Sbjct: 197 YVRQCGGTARIFSVTNG-GQERKFVGGSGQVSEQIMGLLG-DKVKLSSPVTYIDQTDDNI 254
Query: 186 EIHTVSGTTYKAKHVILTVPPHLMLNIQFDPPLNPTKIEYFSSVIPGHVIKVILTYETRF 365
+ T++ Y+ K+VI +PP L I F P L P + + + G VIK ++ Y+ F
Sbjct: 255 IVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAF 314
Query: 366 WMSGGYSGEIVSNGGPSFIDGCSTGPLCVVFDATTENNS-PALVCFI 503
W Y G ++ P+ + D T + S PA++ FI
Sbjct: 315 WKKKDYCGCMIIED--------EEAPIAITLDDTKPDGSLPAIMGFI 353
>sp|Q8BW75|AOFB_MOUSE Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 66.6 bits (161), Expect = 3e-11
Identities = 37/134 (27%), Positives = 66/134 (49%)
Frame = +3
Query: 6 FANSCGGFHNFLESGEGTAHGYKIVGGAARILSTILEVIGSDTIDIHTVVSSISKKDTHS 185
+ CGG + + G K +GG+ ++ I +++G D + + V I + +
Sbjct: 188 YVKQCGGTTRIISTTNG-GQERKFIGGSGQVSERIKDILG-DRVKLERPVIHIDQTGENV 245
Query: 186 EIHTVSGTTYKAKHVILTVPPHLMLNIQFDPPLNPTKIEYFSSVIPGHVIKVILTYETRF 365
+ T++ Y+AK+VI +PP L + I + PPL + + S V G VIK ++ Y+ F
Sbjct: 246 IVKTLNHEIYEAKYVISAIPPALGMKIHYSPPLPMLRNQLISRVPLGSVIKCMVYYKEPF 305
Query: 366 WMSGGYSGEIVSNG 407
W + G +V G
Sbjct: 306 WRKKDFCGTMVIEG 319
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,008,103
Number of Sequences: 369166
Number of extensions: 1366804
Number of successful extensions: 3213
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3089
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3207
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3551563800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)