Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_N22
(826 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P08574|CY1_HUMAN Cytochrome c1, heme protein, mitochondr... 311 2e-84
sp|Q9D0M3|CY1_MOUSE Cytochrome c1, heme protein, mitochondr... 308 9e-84
sp|P00125|CY1_BOVIN Cytochrome c1, heme protein, mitochondr... 303 3e-82
sp|P25076|CY11_SOLTU Cytochrome c1, heme protein, mitochond... 270 4e-72
sp|P29610|CY12_SOLTU Cytochrome c1, heme protein, mitochond... 267 2e-71
sp|P07142|CY1_NEUCR Cytochrome c1, heme protein, mitochondr... 252 8e-67
sp|P07143|CY1_YEAST Cytochrome c1, heme protein, mitochondr... 250 4e-66
sp|Q00988|CY1_KLULA Cytochrome c1, heme protein, mitochondr... 247 2e-65
sp|P20114|CY1_EUGGR Cytochrome c1, heme protein 197 2e-50
sp|P51131|CYBC_BRAJA Cytochrome b/c1 [Contains: Cytochrome ... 195 1e-49
>sp|P08574|CY1_HUMAN Cytochrome c1, heme protein, mitochondrial precursor (Cytochrome
c-1)
Length = 325
Score = 311 bits (796), Expect = 2e-84
Identities = 144/246 (58%), Positives = 182/246 (73%)
Frame = +2
Query: 65 GTVVCGAAVTTLAVSFAVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQVC 244
G + G A +A+ AV+ ASDL HPPS PW H GL S DH +IRRG+QVYKQVC
Sbjct: 65 GMLAAGGAGLAVALHSAVS---ASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVC 121
Query: 245 AACHSMKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPKPYAN 424
A+CHSM F++YRHLVGVC TEDEAK+ AAE+ V DGPN++G M+ RPG+L DYFPKPY N
Sbjct: 122 ASCHSMDFVAYRHLVGVCYTEDEAKELAAEVEVQDGPNEDGEMFMRPGKLFDYFPKPYPN 181
Query: 425 DELARKANNGALPPDLSLIVKAREGGEDYIFQILTGYCDPPAGRNLDEGQYYNPYFPGGG 604
E AR ANNGALPPDLS IV+AR GGEDY+F +LTGYC+PP G +L EG Y+NPYFPG
Sbjct: 182 SEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQA 241
Query: 605 ISMAQALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRKKFAPRFYLTIGFLIA 784
I+MA +Y +++E+ DGTPAT SQ+AKDV TFL W +P + RK+ + + + L+
Sbjct: 242 IAMAPPIYTDVLEFDDGTPATMSQIAKDVCTFLRWASEPEHDHRKRMGLKMLMMMALLVP 301
Query: 785 IVFYIE 802
+V+ I+
Sbjct: 302 LVYTIK 307
>sp|Q9D0M3|CY1_MOUSE Cytochrome c1, heme protein, mitochondrial precursor (Cytochrome
c-1)
Length = 325
Score = 308 bits (790), Expect = 9e-84
Identities = 143/243 (58%), Positives = 177/243 (72%)
Frame = +2
Query: 65 GTVVCGAAVTTLAVSFAVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQVC 244
G + G A +A+ AV+ ASDL HPPS PW H GL S DH +IRRG+QVYKQVC
Sbjct: 65 GMLAAGGAGLAVALHSAVS---ASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVC 121
Query: 245 AACHSMKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPKPYAN 424
++CHSM +++YRHLVGVC TE+EAK A E+ V DGPND+G M+ RPG+L DYFPKPY N
Sbjct: 122 SSCHSMDYVAYRHLVGVCYTEEEAKALAEEVEVQDGPNDDGEMFMRPGKLSDYFPKPYPN 181
Query: 425 DELARKANNGALPPDLSLIVKAREGGEDYIFQILTGYCDPPAGRNLDEGQYYNPYFPGGG 604
E AR ANNGALPPDLS IV+AR GGEDY+F +LTGYC+PP G +L EG Y+NPYFPG
Sbjct: 182 PEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQA 241
Query: 605 ISMAQALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRKKFAPRFYLTIGFLIA 784
I MA +Y E++EY DGTPAT SQ+AKDV TFL W +P + RK+ + L +G L+
Sbjct: 242 IGMAPPIYTEVLEYDDGTPATMSQVAKDVATFLRWASEPEHDHRKRMGLKMLLMMGLLLP 301
Query: 785 IVF 793
+ +
Sbjct: 302 LTY 304
>sp|P00125|CY1_BOVIN Cytochrome c1, heme protein, mitochondrial (Cytochrome c-1)
Length = 241
Score = 303 bits (777), Expect = 3e-82
Identities = 136/220 (61%), Positives = 168/220 (76%)
Frame = +2
Query: 134 SDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQVCAACHSMKFISYRHLVGVCLTEDE 313
SDL HPPS PW H GL S DH +IRRG+QVYKQVC++CHSM +++YRHLVGVC TEDE
Sbjct: 1 SDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEDE 60
Query: 314 AKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPKPYANDELARKANNGALPPDLSLIVKAR 493
AK A E+ V DGPN++G M+ RPG+L DYFPKPY N E AR ANNGALPPDLS IV+AR
Sbjct: 61 AKALAEEVEVQDGPNEDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRAR 120
Query: 494 EGGEDYIFQILTGYCDPPAGRNLDEGQYYNPYFPGGGISMAQALYDEIIEYPDGTPATTS 673
GGEDY+F +LTGYC+PP G +L EG Y+NPYFPG I MA +Y+E++E+ DGTPAT S
Sbjct: 121 HGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYNEVLEFDDGTPATMS 180
Query: 674 QLAKDVVTFLTWTGDPHLEKRKKFAPRFYLTIGFLIAIVF 793
Q+AKDV TFL W +P + RK+ + L +G L+ +V+
Sbjct: 181 QVAKDVCTFLRWAAEPEHDHRKRMGLKMLLMMGLLLPLVY 220
>sp|P25076|CY11_SOLTU Cytochrome c1, heme protein, mitochondrial precursor (Clone
PC13III)
Length = 320
Score = 270 bits (690), Expect = 4e-72
Identities = 142/258 (55%), Positives = 177/258 (68%), Gaps = 5/258 (1%)
Frame = +2
Query: 35 LKSKWTKRIGGTVVCGAAVTTLAVSFAVTPAYASDLIAHP---PSLPWYHSGLTHSYDHA 205
L S +K GA V+ L +SFA T AY SD H P+ PW H G+ SYDHA
Sbjct: 47 LGSAGSKSFRALAAIGAGVSGL-LSFA-TIAY-SDEAEHGLECPNYPWPHEGILSSYDHA 103
Query: 206 AIRRGYQVYKQVCAACHSMKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRP 385
+IRRG+QVY+QVCA+CHSM ISYR LVGV TE+E K AAEI V+DGPNDEG M+ RP
Sbjct: 104 SIRRGHQVYQQVCASCHSMSLISYRDLVGVAYTEEETKAMAAEIEVVDGPNDEGEMFTRP 163
Query: 386 GRLGDYFPKPYANDELARKANNGALPPDLSLIVKAREGGEDYIFQILTGYCDPPAGRNLD 565
G+L D FP+PYAN+ AR AN GA PPDLSLI KAR G++Y+F +LT Y DPPAG ++
Sbjct: 164 GKLSDRFPQPYANEAAARFANGGAYPPDLSLITKARHNGQNYVFALLTAYRDPPAGVSIR 223
Query: 566 EGQYYNPYFPGGGISMAQALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRK-- 739
EG +YNPYFPGG I+M + L D +EY DG PAT +Q+ KDVV+FL+W +P +E+RK
Sbjct: 224 EGLHYNPYFPGGAIAMPKMLNDGAVEYEDGIPATEAQMGKDVVSFLSWAAEPEMEERKLM 283
Query: 740 KFAPRFYLTIGFLIAIVF 793
F F L++ L A +
Sbjct: 284 GFKWIFVLSLALLQAAYY 301
>sp|P29610|CY12_SOLTU Cytochrome c1, heme protein, mitochondrial precursor (Clone PC18I)
Length = 260
Score = 267 bits (683), Expect = 2e-71
Identities = 132/240 (55%), Positives = 166/240 (69%), Gaps = 2/240 (0%)
Frame = +2
Query: 80 GAAVTTLAVSFAVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQVCAACHS 259
GA V+ L V A ++ PS PW H+G+ SYDHA+IRRG+QVY+QVCA+CHS
Sbjct: 2 GAGVSGLLGFATVASADEAEHGLECPSYPWPHAGILSSYDHASIRRGHQVYQQVCASCHS 61
Query: 260 MKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPKPYANDELAR 439
M +SYR LVGV TE+E K AAEI V DGPNDEG M+ RPG+L D FP+PY N+ AR
Sbjct: 62 MSLVSYRDLVGVAYTEEEVKAMAAEIEVEDGPNDEGEMFTRPGKLSDRFPQPYPNEAAAR 121
Query: 440 KANNGALPPDLSLIVKAREGGEDYIFQILTGYCDPPAGRNLDEGQYYNPYFPGGGISMAQ 619
AN GA PPDLSLI KAR G++Y+F +LT Y DPPAG ++ EG +YNPYFPGG I+M +
Sbjct: 122 FANGGAYPPDLSLITKARHNGQNYVFALLTAYRDPPAGVSIREGLHYNPYFPGGAIAMPK 181
Query: 620 ALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRK--KFAPRFYLTIGFLIAIVF 793
L D +EY DG PAT +Q+ KDVV+FLTW +P +E+RK F F L++ L A +
Sbjct: 182 MLNDGAVEYEDGVPATEAQMGKDVVSFLTWAAEPEMEERKLMGFKWIFVLSLALLQAAYY 241
>sp|P07142|CY1_NEUCR Cytochrome c1, heme protein, mitochondrial precursor
Length = 332
Score = 252 bits (644), Expect = 8e-67
Identities = 132/276 (47%), Positives = 169/276 (61%), Gaps = 23/276 (8%)
Frame = +2
Query: 44 KWTKRIGGTVVCGAAVTT---LAVSFAVTPAYASDLIA-------------------HPP 157
K+ KR T GAA + L ++ A A A+ IA H
Sbjct: 22 KFAKRSASTQSSGAAAESPLRLNIAAAAATAVAAGSIAWYYHLYGFASAMTPAEEGLHAT 81
Query: 158 SLPWYHSGLTHSYDHAAIRRGYQVYKQVCAACHSMKFISYRHLVGVCLTEDEAKQEAAEI 337
PW H ++DH A+RRG+QVY++VCA+CHS+ + YR LVG LT DEAK A E
Sbjct: 82 KYPWVHEQWLKTFDHQALRRGFQVYREVCASCHSLSRVPYRALVGTILTVDEAKALAEEN 141
Query: 338 NVLDGPNDEGLMYDRPGRLGDYFPKPYANDELARKANNGALPPDLSLIVKAREGGEDYIF 517
PND+G + RPG+L DY P PY NDE AR ANNGALPPDLSLIVKAR GG DYIF
Sbjct: 142 EYDTEPNDQGEIEKRPGKLSDYLPDPYKNDEAARFANNGALPPDLSLIVKARHGGCDYIF 201
Query: 518 QILTGYCD-PPAGRNLDEGQYYNPYFPGGGISMAQALYDEIIEYPDGTPATTSQLAKDVV 694
+LTGY D PPAG ++ G +NPYFPG GI+MA+ LYD +++Y DGTPA+TSQ+AKDVV
Sbjct: 202 SLLTGYPDEPPAGASVGAGLNFNPYFPGTGIAMARVLYDGLVDYEDGTPASTSQMAKDVV 261
Query: 695 TFLTWTGDPHLEKRKKFAPRFYLTIGFLIAIVFYIE 802
FL W +P ++ RK+ + + L A+ Y++
Sbjct: 262 EFLNWAAEPEMDDRKRMGMKVLVVTSVLFALSVYVK 297
>sp|P07143|CY1_YEAST Cytochrome c1, heme protein, mitochondrial precursor
Length = 309
Score = 250 bits (638), Expect = 4e-66
Identities = 123/249 (49%), Positives = 164/249 (65%), Gaps = 3/249 (1%)
Frame = +2
Query: 65 GTVVCGAAVTTL--AVSFAVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQ 238
G G +TL A S A++ H P+ W H+G ++DHA+IRRGYQVY++
Sbjct: 40 GVAAAGITASTLLYADSLTAEAMTAAEHGLHAPAYAWSHNGPFETFDHASIRRGYQVYRE 99
Query: 239 VCAACHSMKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPKPY 418
VCAACHS+ +++R LVGV T +E + A E D P+++G RPG+L DY P PY
Sbjct: 100 VCAACHSLDRVAWRTLVGVSHTNEEVRNMAEEFEYDDEPDEQGNPKKRPGKLSDYIPGPY 159
Query: 419 ANDELARKANNGALPPDLSLIVKAREGGEDYIFQILTGYCD-PPAGRNLDEGQYYNPYFP 595
N++ AR AN GALPPDLSLIVKAR GG DYIF +LTGY D PPAG L G YNPYFP
Sbjct: 160 PNEQAARAANQGALPPDLSLIVKARHGGCDYIFSLLTGYPDEPPAGVALPPGSNYNPYFP 219
Query: 596 GGGISMAQALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRKKFAPRFYLTIGF 775
GG I+MA+ L+D+++EY DGTPATTSQ+AKDV TFL W +P ++RK+ + + +
Sbjct: 220 GGSIAMARVLFDDMVEYEDGTPATTSQMAKDVTTFLNWCAEPEHDERKRLGLKTVIILSS 279
Query: 776 LIAIVFYIE 802
L + +++
Sbjct: 280 LYLLSIWVK 288
>sp|Q00988|CY1_KLULA Cytochrome c1, heme protein, mitochondrial precursor
Length = 292
Score = 247 bits (631), Expect = 2e-65
Identities = 121/251 (48%), Positives = 164/251 (65%), Gaps = 3/251 (1%)
Frame = +2
Query: 59 IGGTVVCGAAVTTL--AVSFAVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVY 232
+GG V G +T+ A S A++ H P W H+G ++DH++IRRGYQVY
Sbjct: 23 VGGAAVVGIGASTMLYADSLTADAMTAAEHGLHAPGYGWSHNGPLETFDHSSIRRGYQVY 82
Query: 233 KQVCAACHSMKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPK 412
++VCAACHS+ +++R +VGV T E + A E D P+D+G RPG+L DY P
Sbjct: 83 REVCAACHSLDRVAWRTMVGVSHTNAEVRAMAEEFEYDDEPDDQGNPKKRPGKLADYVPG 142
Query: 413 PYANDELARKANNGALPPDLSLIVKAREGGEDYIFQILTGYC-DPPAGRNLDEGQYYNPY 589
PY N++ AR AN GALPPDLSLIVKAR GG DYIF +LTGY +PPAG L G YNPY
Sbjct: 143 PYPNEQAARAANQGALPPDLSLIVKARHGGPDYIFALLTGYPEEPPAGVVLPPGANYNPY 202
Query: 590 FPGGGISMAQALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRKKFAPRFYLTI 769
FPGG I+M + L+D+++EY DGTPATTSQ+AKDV TFL W +P ++RK+ + + +
Sbjct: 203 FPGGSIAMGRVLFDDLVEYEDGTPATTSQMAKDVTTFLHWCSEPEHDERKRLGLKAMIVL 262
Query: 770 GFLIAIVFYIE 802
L + +++
Sbjct: 263 SSLYLLSVWVK 273
>sp|P20114|CY1_EUGGR Cytochrome c1, heme protein
Length = 243
Score = 197 bits (502), Expect = 2e-50
Identities = 104/215 (48%), Positives = 133/215 (61%), Gaps = 1/215 (0%)
Frame = +2
Query: 146 AHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQVCAACHSMKFISYRHLVGVCLTEDEAKQE 325
+HPP+LPW H D ++RRG +VY+QV A CHS+ FI YRH ++++E K
Sbjct: 4 SHPPALPWPHFQWFQGLDWRSVRRGKEVYEQVFAPCHSLSFIKYRHFEAF-MSKEEVKNM 62
Query: 326 AAEINVLDGPNDEGLMYDRPGRLGDYFPKPYANDELARKANNGALPPDLSLIVKAREGGE 505
AA V D P+++G RPG+ D +PY N++ AR ANNGALPPDLS+I AR GG
Sbjct: 63 AASFEVDDDPDEKGEARKRPGKRFDTVVQPYKNEQEARYANNGALPPDLSVITNARHGGV 122
Query: 506 DYIFQILTGYCDP-PAGRNLDEGQYYNPYFPGGGISMAQALYDEIIEYPDGTPATTSQLA 682
DYI+ +LTGY P P G L Q+YNPYF GG I M L D++IEY DGTPA+ Q+A
Sbjct: 123 DYIYALLTGYGRPVPGGVQLSTTQWYNPYFHGGIIGMPPPLTDDMIEYEDGTPASVPQMA 182
Query: 683 KDVVTFLTWTGDPHLEKRKKFAPRFYLTIGFLIAI 787
KDV FL W +P ++RK Y TI L I
Sbjct: 183 KDVTCFLEWCSNPWWDERKLLG---YKTIATLAVI 214
>sp|P51131|CYBC_BRAJA Cytochrome b/c1 [Contains: Cytochrome b; Cytochrome c1]
Length = 687
Score = 195 bits (496), Expect = 1e-49
Identities = 102/271 (37%), Positives = 151/271 (55%), Gaps = 26/271 (9%)
Frame = +2
Query: 62 GGTVVCGAAVTTLAVSF----AVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQV 229
GG V A+ +A ++ A A++ PP W +G +D A++RG +V
Sbjct: 407 GGKAVASVAIALVAAGALFLGSLQDARANEGSDKPPGNKWSFAGPFGKFDRGALQRGLKV 466
Query: 230 YKQVCAACHSMKFISYRHLV---GVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGD 400
YK+VCA+CH + +I++R+L G + + A++ + DGPND G M++RPGR D
Sbjct: 467 YKEVCASCHGLSYIAFRNLAEAGGPSYSVAQVAAFASDYKIKDGPNDAGDMFERPGRPAD 526
Query: 401 YFPKPYANDELARKANNGALPPDLSLIVKAR------------------EGGEDYIFQIL 526
YFP P+ N++ AR AN GA PPDLSLI KAR E G DY+ +L
Sbjct: 527 YFPSPFPNEQAARAANGGAAPPDLSLITKARSYGRGFPWFIFDFFTQYQEQGPDYVSAVL 586
Query: 527 TGYCDP-PAGRNLDEGQYYNPYFPGGGISMAQALYDEIIEYPDGTPATTSQLAKDVVTFL 703
G+ + P G + EG YYN YFPG I M + L D + Y DG+PAT +Q +KDV TFL
Sbjct: 587 QGFEEKVPEGVTIPEGSYYNKYFPGHAIKMPKPLSDGQVTYDDGSPATVAQYSKDVTTFL 646
Query: 704 TWTGDPHLEKRKKFAPRFYLTIGFLIAIVFY 796
WT +PH+E RK+ + ++ + ++++
Sbjct: 647 MWTAEPHMEARKRLGFQVFVFLIIFAGLMYF 677
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,009,227
Number of Sequences: 369166
Number of extensions: 2078700
Number of successful extensions: 5219
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5054
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5201
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7956112725
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)