Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_N08
(826 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P25439|BRM_DROME Homeotic gene regulator (Brahma protein) 162 1e-39
sp|P51531|SMCA2_HUMAN Possible global transcription activat... 161 2e-39
sp|P51532|SMCA4_HUMAN Possible global transcription activat... 155 1e-37
sp|O94421|SNF22_SCHPO SNF2-family ATP dependent chromatin r... 87 4e-17
sp|Q9UTN6|SNF21_SCHPO SNF2-family ATP dependent chromatin r... 86 1e-16
sp|Q86U86|PB1_HUMAN Polybromo-1 protein (hPB1) (Polybromo-1... 70 9e-12
sp|P22082|SNF2_YEAST Transcription regulatory protein SNF2 ... 68 3e-11
sp|P32597|STH1_YEAST Nuclear protein STH1/NPS1 (Chromatin s... 67 5e-11
sp|Q09948|BRD1_SCHPO Bromodomain protein brd1 53 1e-06
sp|Q9UUK2|GCN5_SCHPO Histone acetyltransferase gcn5 50 1e-05
>sp|P25439|BRM_DROME Homeotic gene regulator (Brahma protein)
Length = 1638
Score = 162 bits (409), Expect = 1e-39
Identities = 104/281 (37%), Positives = 150/281 (53%), Gaps = 8/281 (2%)
Frame = +1
Query: 7 RIRHEARFKLNVDEKVIQAGMFDQKSTDKDRKTYLKALL-XXXXXXXXXXXXXXXXTINQ 183
RI AR+KLN+DEKVIQAGMFDQKST +R+ +L+ +L IN
Sbjct: 1231 RILAAARYKLNMDEKVIQAGMFDQKSTGSERQQFLQTILHQDDNEEEEENEVPDDEMINM 1290
Query: 184 MLARSEEEFEIYQRMDIERELNEKNKPVVKCRLLVADEIPENIDYNDSLDEEVQQVQDDY 363
M+ARSEEE EI++RMD ER+ ++ + RL+ E+P D+ D+EV++ Y
Sbjct: 1291 MIARSEEEIEIFKRMDAERKKEDEEIHPGRERLIDESELP---DWLTKDDDEVERFHYQY 1347
Query: 364 -------MGKRNRKEVDYSDALMEHEFLKAIDXXXXXXXXXSQXXXXXXXXXXXNEGSSE 522
G R RKEVDY+D+L E E+LKAID +E E
Sbjct: 1348 DEDTILGRGSRQRKEVDYTDSLTEKEWLKAID-----------------DGAEFDEEEEE 1390
Query: 523 DESSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKLMERMQMLLNIVIDYRDKDGRVLSE 702
D+S + + ++M +++ VI + ++DGR LSE
Sbjct: 1391 DDSKRKRRKRKNRKEESDDDSLILKRRRRQNLDKRSKKQMHKIMSAVIKH-NQDGRTLSE 1449
Query: 703 PFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDNKYRSIDD 825
PFMKLPSR+ LPDYY+IIK+P+D ++I QR++D KY +++
Sbjct: 1450 PFMKLPSRQRLPDYYEIIKRPVDIKKILQRIEDCKYADLNE 1490
>sp|P51531|SMCA2_HUMAN Possible global transcription activator SNF2L2 (SNF2-alpha)
(SWI/SNF-related matrix associated actin dependent
regulator of chromatin subfamily A member 2)
Length = 1586
Score = 161 bits (407), Expect = 2e-39
Identities = 95/295 (32%), Positives = 157/295 (53%), Gaps = 22/295 (7%)
Frame = +1
Query: 7 RIRHEARFKLNVDEKVIQAGMFDQKSTDKDRKTYLKALLXXXXXXXXXXXXXXXXTINQM 186
+I A++KLNVD+KVIQAGMFDQKS+ +R+ +L+A+L T+NQM
Sbjct: 1179 KILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQM 1238
Query: 187 LARSEEEFEIYQRMDIERELNEKNKPVVKCRLLVADEIPENIDYNDSLDEEVQQVQDDY- 363
+AR EEEF+++ RMD++R + P K RL+ DE+P I +D+ E + +++
Sbjct: 1239 IARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEK 1298
Query: 364 ---MGKRNRKEVDYSDALMEHEFLKAIDXXXXXXXXXSQXXXXXXXXXXXNEGSSEDESS 534
G R R++VDYSDAL E ++L+AI+ ++ ++++
Sbjct: 1299 IFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVE 1358
Query: 535 KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKLMERMQMLLNIVIDYRD------------ 678
K KL ++M +++ I+Y+D
Sbjct: 1359 K-----------AKKRRGRPPAEKLSPNPPKLTKQMNAIIDTCINYKDSCNVEKVPSNSQ 1407
Query: 679 ------KDGRVLSEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDNKYRSIDD 825
GR LSE F++LPSRK+LP+YY++I+KP+DF++I++R++++KYRS+ D
Sbjct: 1408 LEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGD 1462
>sp|P51532|SMCA4_HUMAN Possible global transcription activator SNF2L4 (SNF2-beta) (BRG-1
protein) (Mitotic growth and transcription activator)
(Brahma protein homolog 1) (SWI/SNF-related matrix
associated actin dependent regulator of chromatin
subfamily A member 4)
Length = 1647
Score = 155 bits (393), Expect = 1e-37
Identities = 102/313 (32%), Positives = 159/313 (50%), Gaps = 40/313 (12%)
Frame = +1
Query: 7 RIRHEARFKLNVDEKVIQAGMFDQKSTDKDRKTYLKALLXXXXXXXXXXXXXXXX----- 171
+I A++KLNVD+KVIQAGMFDQKS+ +R+ +L+A+L
Sbjct: 1213 KILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFA 1272
Query: 172 ----------------------------TINQMLARSEEEFEIYQRMDIERELNEKNKPV 267
T+NQM+AR EEEF+++ RMD++R E P
Sbjct: 1273 HTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPK 1332
Query: 268 VKCRLLVADEIPENIDYNDSLDEEVQQVQDDYM----GKRNRKEVDYSDALMEHEFLKAI 435
K RL+ DE+P I +D+ E + +++ G R+RKEVDYSD+L E ++LKAI
Sbjct: 1333 RKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAI 1392
Query: 436 DXXXXXXXXXS--QXXXXXXXXXXXNEGSSEDESSKXXXXXXXXXXXXXXXXXXXXXXXX 609
+ Q + GSS +S
Sbjct: 1393 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1452
Query: 610 XXXXXKLMERMQMLLNIVIDYRDKD-GRVLSEPFMKLPSRKDLPDYYDIIKKPMDFQRIR 786
L ++M+ +++ VI Y+D GR LSE F++LPSRK+LP+YY++I+KP+DF++I+
Sbjct: 1453 PNPP-NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIK 1511
Query: 787 QRLKDNKYRSIDD 825
+R++++KYRS++D
Sbjct: 1512 ERIRNHKYRSLND 1524
>sp|O94421|SNF22_SCHPO SNF2-family ATP dependent chromatin remodeling factor snf22
Length = 1680
Score = 87.4 bits (215), Expect = 4e-17
Identities = 70/284 (24%), Positives = 132/284 (46%), Gaps = 12/284 (4%)
Frame = +1
Query: 10 IRHEARFKLNVDEKVIQAGMFDQKSTDKDRKTYLKALL--XXXXXXXXXXXXXXXXTINQ 183
I A++KL++D KVIQAG FD KST ++R+ +L++LL +N+
Sbjct: 1321 ILSRAQYKLDLDGKVIQAGKFDNKSTPEEREAFLRSLLEHDGDDDHDLTYGELQDDELNE 1380
Query: 184 MLARSEEEFEIYQRMDIER---ELNEKNKPVVKCRLLVADEIPE--NIDYNDSLDEEVQQ 348
+++R++EE +++++D ER ++ K KP+ RLL +E+P+ ++ + + +
Sbjct: 1381 LISRTDEELVLFKKLDKERAATDIYGKGKPLE--RLLTVNELPDFYKVEVDSFAVQSSSE 1438
Query: 349 VQDDYMGKRNRKEVDYSDALMEHEFLKAIDXXXXXXXXXSQXXXXXXXXXXXNEGSS--- 519
++D Y+ ++ R+ S + + L +D + N GSS
Sbjct: 1439 LEDQYLERKRRRRNSISYTELTLDELNTVDDPSSTLMPRKR----GRPRKKTNSGSSLST 1494
Query: 520 --EDESSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKLMERMQMLLNIVIDYRDKDGRV 693
ESS ME + L N+ + +DGR
Sbjct: 1495 PLSQESS-----------LARSGRKNTPSYKQKALRRYCMEIFERLYNL----QSEDGRF 1539
Query: 694 LSEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDNKYRSIDD 825
++ F+ P+RK PDYY IIK+P+ +I++ +K+++Y + +
Sbjct: 1540 VNGLFLYPPNRKLYPDYYIIIKRPIALGKIKRNIKNDRYGDVGE 1583
>sp|Q9UTN6|SNF21_SCHPO SNF2-family ATP dependent chromatin remodeling factor snf21
Length = 1199
Score = 85.9 bits (211), Expect = 1e-16
Identities = 68/274 (24%), Positives = 126/274 (45%), Gaps = 7/274 (2%)
Frame = +1
Query: 22 ARFKLNVDEKVIQAGMFDQKSTDKDRKTYLKALL--XXXXXXXXXXXXXXXXTINQMLAR 195
A++KL++D KVIQAG FD KST ++R+ +L++LL +N++LAR
Sbjct: 874 AQYKLDIDGKVIQAGKFDNKSTPEEREAFLRSLLENENGEEENDEKGELDDDELNEILAR 933
Query: 196 SEEEFEIYQRM--DIERELNEKNKPVVKCRLLVADEIPENIDYNDSLDEEVQQVQDDYMG 369
++E ++++M D+ERE + K K RL+ E+PE + ++ +Q++ +G
Sbjct: 934 GDDELRLFKQMTEDLERE-SPYGKNKEKERLIQVSELPE-FYQREEPEKTTDLLQEEPLG 991
Query: 370 K--RNRKEVDYSDALMEHEFLKAIDXXXXXXXXXSQXXXXXXXXXXXNEGSSEDESSKXX 543
+ R R V Y +A+ + +++ +D G + +
Sbjct: 992 RGARRRTPVVYDEAVRDAQWMAEMD---------------MESEARPTRGRPKRNIASVD 1036
Query: 544 XXXXXXXXXXXXXXXXXXXXXXXXXXXKLMERMQM-LLNIVIDYRDKDGRVLSEPFMKLP 720
L+ R+ + + V + D +GR L++ F++LP
Sbjct: 1037 ETPALTLNGKPKKKRGPAPDTLTSEHRSLLRRVCLEIYKAVNELEDDNGRPLNKLFLELP 1096
Query: 721 SRKDLPDYYDIIKKPMDFQRIRQRLKDNKYRSID 822
S+K PDYY IIK P+ IR+ + Y++++
Sbjct: 1097 SKKLYPDYYMIIKSPIALDAIRKHINGTFYKTLE 1130
>sp|Q86U86|PB1_HUMAN Polybromo-1 protein (hPB1) (Polybromo-1D) (BRG1-associated factor
180) (BAF180)
Length = 1689
Score = 69.7 bits (169), Expect = 9e-12
Identities = 37/70 (52%), Positives = 45/70 (64%), Gaps = 4/70 (5%)
Frame = +1
Query: 625 KLMERMQMLLNIVID----YRDKDGRVLSEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQR 792
K M MQ LN V + Y DK GR LS F++LPSR +LPDYY IKKPMD ++IR
Sbjct: 653 KYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSH 712
Query: 793 LKDNKYRSID 822
+ NKY+ ID
Sbjct: 713 MMANKYQDID 722
Score = 61.6 bits (148), Expect = 2e-09
Identities = 23/58 (39%), Positives = 42/58 (72%)
Frame = +1
Query: 649 LLNIVIDYRDKDGRVLSEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDNKYRSID 822
L N + DY+D+ GR+L E F++ P R++ PDYY+++ +P+D +I+Q+LK +Y ++
Sbjct: 53 LYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVN 110
Score = 61.6 bits (148), Expect = 2e-09
Identities = 28/64 (43%), Positives = 43/64 (67%)
Frame = +1
Query: 628 LMERMQMLLNIVIDYRDKDGRVLSEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDNK 807
L E ++ LL ++ + GR++SE F KLPS+ PDYY IIK+P+D + I QR+++
Sbjct: 182 LKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGS 241
Query: 808 YRSI 819
Y+SI
Sbjct: 242 YKSI 245
Score = 57.8 bits (138), Expect = 4e-08
Identities = 25/58 (43%), Positives = 39/58 (67%)
Frame = +1
Query: 649 LLNIVIDYRDKDGRVLSEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDNKYRSID 822
L + V R+ G++++EPF LPS+K PDYY IK P+ Q+IR +LK+ +Y ++D
Sbjct: 389 LYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLD 446
Score = 57.8 bits (138), Expect = 4e-08
Identities = 27/60 (45%), Positives = 42/60 (70%), Gaps = 1/60 (1%)
Frame = +1
Query: 634 ERMQMLLNIVIDYRDK-DGRVLSEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDNKY 810
+RM++L N+V++ R+ GR L + FM PS+KD PDYY II +PMD + I ++++KY
Sbjct: 521 QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKY 580
>sp|P22082|SNF2_YEAST Transcription regulatory protein SNF2 (SWI/SNF complex component
SNF2) (Regulatory protein SWI2) (Regulatory protein GAM1)
(Transcription factor TYE3)
Length = 1703
Score = 68.2 bits (165), Expect = 3e-11
Identities = 50/154 (32%), Positives = 76/154 (49%), Gaps = 11/154 (7%)
Frame = +1
Query: 10 IRHEARFKLNVDEKVIQAGMFDQKSTDKDRKTYLKALL-------XXXXXXXXXXXXXXX 168
I A KL++D KVIQAG FD KST ++++ L++LL
Sbjct: 1221 ILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRESGVEEEEELKD 1280
Query: 169 XTINQMLARSEEEFEIYQRMDIERELNEKNKPVVKCRLLVADEIPE--NIDYNDSLDEEV 342
IN++LAR++EE + RMD +R E+ VK RLL E+P+ + D L E
Sbjct: 1281 SEINEILARNDEEMAVLTRMDEDRSKKEEELG-VKSRLLEKSELPDIYSRDIGAELKREE 1339
Query: 343 QQVQDDYMGK--RNRKEVDYSDALMEHEFLKAID 438
+ Y G+ R RK Y+D + E ++L+ +
Sbjct: 1340 SESAAVYNGRGARERKTATYNDNMSEEQWLRQFE 1373
Score = 45.4 bits (106), Expect = 2e-04
Identities = 22/67 (32%), Positives = 38/67 (56%)
Frame = +1
Query: 625 KLMERMQMLLNIVIDYRDKDGRVLSEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDN 804
K+ ++ L + ++Y ++ GR LS+ F+ PS+ PDYY IIK P+ F I ++
Sbjct: 1549 KVAKQALDLYHFALNYENEAGRKLSDIFLSKPSKALYPDYYMIIKYPVAFDNINTHIETL 1608
Query: 805 KYRSIDD 825
Y S+ +
Sbjct: 1609 AYNSLKE 1615
>sp|P32597|STH1_YEAST Nuclear protein STH1/NPS1 (Chromatin structure remodeling complex
protein STH1) (SNF2 homolog)
Length = 1359
Score = 67.4 bits (163), Expect = 5e-11
Identities = 46/151 (30%), Positives = 79/151 (52%), Gaps = 8/151 (5%)
Frame = +1
Query: 10 IRHEARFKLNVDEKVIQAGMFDQKSTDKDRKTYLKALL-XXXXXXXXXXXXXXXXTINQM 186
I A KL++D KVIQAG FD KST ++++ +L+ L+ +N
Sbjct: 925 ILERAMQKLDIDGKVIQAGKFDNKSTAEEQEAFLRRLIESETNRDDDDKAELDDDELNDT 984
Query: 187 LARSEEEFEIYQRMDIERELNEK------NKPVVKCRLLVADEIPENIDYNDSLDEEVQQ 348
LARS +E ++ ++D ER E+ V RL+ DE+P+ + + ++E ++
Sbjct: 985 LARSADEKILFDKIDKERMNQERADAKAQGLRVPPPRLIQLDELPK--VFREDIEEHFKK 1042
Query: 349 VQDDYMGK-RNRKEVDYSDALMEHEFLKAID 438
+ +G+ R +K V Y D L E +FL+A++
Sbjct: 1043 EDSEPLGRIRQKKRVYYDDGLTEEQFLEAVE 1073
Score = 44.7 bits (104), Expect = 3e-04
Identities = 23/67 (34%), Positives = 39/67 (58%)
Frame = +1
Query: 625 KLMERMQMLLNIVIDYRDKDGRVLSEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDN 804
KL+E M+ L+ V D + F KLPS++D PDY+ +I+KPM I + K+
Sbjct: 1257 KLVEEMREQLDEV------DSHPRTSIFEKLPSKRDYPDYFKVIEKPMAIDIILKNCKNG 1310
Query: 805 KYRSIDD 825
Y+++++
Sbjct: 1311 TYKTLEE 1317
>sp|Q09948|BRD1_SCHPO Bromodomain protein brd1
Length = 542
Score = 52.8 bits (125), Expect = 1e-06
Identities = 22/61 (36%), Positives = 41/61 (67%)
Frame = +1
Query: 640 MQMLLNIVIDYRDKDGRVLSEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDNKYRSI 819
+Q +L+ + + +D+ GR L + F+ LPS++ PDYY+IIK PM + + +R K +Y ++
Sbjct: 148 IQNILDALHEEKDEQGRFLIDIFIDLPSKRLYPDYYEIIKSPMTIKMLEKRFKKGEYTTL 207
Query: 820 D 822
+
Sbjct: 208 E 208
Score = 50.8 bits (120), Expect = 4e-06
Identities = 21/59 (35%), Positives = 37/59 (62%)
Frame = +1
Query: 649 LLNIVIDYRDKDGRVLSEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDNKYRSIDD 825
+L ++ +D +G + F +LPS++ PDYY II+KP+ ++ +R + K KY S+ D
Sbjct: 18 VLEALVGLKDNEGNPFDDIFEELPSKRYFPDYYQIIQKPICYKMMRNKAKTGKYLSMGD 76
>sp|Q9UUK2|GCN5_SCHPO Histone acetyltransferase gcn5
Length = 454
Score = 49.7 bits (117), Expect = 1e-05
Identities = 19/43 (44%), Positives = 33/43 (76%)
Frame = +1
Query: 697 SEPFMKLPSRKDLPDYYDIIKKPMDFQRIRQRLKDNKYRSIDD 825
S PFM+ S++D+PDYY++I+ PMD + RL++N+Y S+++
Sbjct: 365 SWPFMQPVSKEDVPDYYEVIEHPMDLSTMEFRLRNNQYESVEE 407
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.316 0.134 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,787,413
Number of Sequences: 369166
Number of extensions: 1303091
Number of successful extensions: 4011
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3839
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4001
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7956112725
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)