Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_014_M22 (632 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q86T03|TM55B_HUMAN Transmembrane protein 55B 103 4e-22 sp|Q5PPM8|TM55B_RAT Transmembrane protein 55B 103 5e-22 sp|O70305|ATX2_MOUSE Ataxin-2 (Spinocerebellar ataxia type ... 35 0.16 sp|Q92667|AKAP1_HUMAN A kinase anchor protein 1, mitochondr... 33 0.79 sp|P41653|YCF2_PINTH Protein ycf2 31 2.3 sp|O04164|C71A6_NEPRA Cytochrome P450 71A6 30 5.1 sp|P49735|MCM2_DROME DNA replication licensing factor MCM2 30 6.7 sp|P30328|COAT_PBCV1 Major capsid protein (VP54) 29 8.8 sp|Q9NWF9|UB7I1_HUMAN E3 ubiquitin ligase TRIAD3 (Ubiquitin... 29 8.8 sp|Q7UKT6|SURE_RHOBA 5'-nucleotidase surE (Nucleoside 5'-mo... 29 8.8
>sp|Q86T03|TM55B_HUMAN Transmembrane protein 55B Length = 277 Score = 103 bits (257), Expect = 4e-22 Identities = 65/171 (38%), Positives = 80/171 (46%) Frame = +1 Query: 13 EATPIKAAPPGKKYVRCTCNGLLICKSSSSRVGCPRPHCKAIITLAPTTDEIGVATGITS 192 EATPIK APPGKKYVRC CN LLICK +S R+ CPRP+CK II L P V G S Sbjct: 109 EATPIKNAPPGKKYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGP------VHPGPLS 162 Query: 193 QTGLLAQSIRVTCVNCSSGFIISVQKQKKYMVAKCPHCQKNSSIGPYYARVRWIIYXXXX 372 +RV C +C + F+ + + +A+CPHC+K SSIG Y R R I Sbjct: 163 PEP-QPMGVRVICGHCKNTFLWTEFTDR--TLARCPHCRKVSSIGRRYPRKRCICCFLLG 219 Query: 373 XXXXXXXXXXXXXXXHKAIDAKGYYVAYXXXXXXXXXXXXRGAIYCCMPIS 525 A G Y A+ R + CM +S Sbjct: 220 LLLAVTATGLAFGTWKHARRYGGIYAAWAFVILLAVLCLGRALYWACMKVS 270
>sp|Q5PPM8|TM55B_RAT Transmembrane protein 55B Length = 284 Score = 103 bits (256), Expect = 5e-22 Identities = 65/171 (38%), Positives = 80/171 (46%) Frame = +1 Query: 13 EATPIKAAPPGKKYVRCTCNGLLICKSSSSRVGCPRPHCKAIITLAPTTDEIGVATGITS 192 EATPIK APPGKKYVRC CN LLICK +S R+ CPRP+CK II L P V G S Sbjct: 116 EATPIKNAPPGKKYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGP------VHPGPLS 169 Query: 193 QTGLLAQSIRVTCVNCSSGFIISVQKQKKYMVAKCPHCQKNSSIGPYYARVRWIIYXXXX 372 +RV C +C + F+ + + +A+CPHC+K SSIG Y R R I Sbjct: 170 PEP-QPMGVRVICGHCKNTFLWTEFTDR--TLARCPHCRKVSSIGRRYPRKRCICCFLLG 226 Query: 373 XXXXXXXXXXXXXXXHKAIDAKGYYVAYXXXXXXXXXXXXRGAIYCCMPIS 525 A G Y A+ R + CM +S Sbjct: 227 LLLAVTATGLAFGTWKPAQQYGGIYAAWAFVILLAVLCLGRALYWGCMKVS 277
>sp|O70305|ATX2_MOUSE Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog) Length = 1285 Score = 35.0 bits (79), Expect = 0.16 Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 5/70 (7%) Frame = +1 Query: 16 ATPIKAAPPGKKYVRCTCNGLLICKSSSSRVGCPRPHCKAI-----ITLAPTTDEIGVAT 180 ATP +A PPG VR + + S+ GCPRP C+ + ++L P AT Sbjct: 108 ATPARACPPG---VRASPPRSGVSSSARPAPGCPRPACEPVYGPLTMSLKPQPQPPAPAT 164 Query: 181 GITSQTGLLA 210 G GLL+ Sbjct: 165 GRKPGGGLLS 174
>sp|Q92667|AKAP1_HUMAN A kinase anchor protein 1, mitochondrial precursor (Protein kinase A anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84) Length = 903 Score = 32.7 bits (73), Expect = 0.79 Identities = 28/100 (28%), Positives = 40/100 (40%) Frame = +1 Query: 22 PIKAAPPGKKYVRCTCNGLLICKSSSSRVGCPRPHCKAIITLAPTTDEIGVATGITSQTG 201 P + +PP K YV C LL + S+ H LA TT + + + G Sbjct: 425 PAEGSPPPKTYVSC-LKSLLSSPTKDSKPNISAHHISLASCLALTTP----SEELPDRAG 479 Query: 202 LLAQSIRVTCVNCSSGFIISVQKQKKYMVAKCPHCQKNSS 321 +L + TCV C +S Q +VA HC + S Sbjct: 480 ILVED--ATCVTC-----MSDSSQSVPLVASPGHCSDSFS 512
>sp|P41653|YCF2_PINTH Protein ycf2 Length = 2054 Score = 31.2 bits (69), Expect = 2.3 Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 6/86 (6%) Frame = +3 Query: 171 RGYRHHQSNRITSSIHSSYLCKLQ*WIYNQCTKTK----EIYGRKMSTLSEKQ*YRSILC 338 R Y+ + + S+ + ++Q W +C K K +I GR + S K+ ++I Sbjct: 948 RSYQDDLLSEMFSNKNEEIFPRIQDWFVTECLKNKIVNEDIDGRSTLSNSSKE-EQNIYR 1006 Query: 339 TSEVDNLFHIG--LNIYRPWDWNYSW 410 S++D++F Y PW + +W Sbjct: 1007 ISQIDSIFSKWDLFKTYMPWFFTSAW 1032
>sp|O04164|C71A6_NEPRA Cytochrome P450 71A6 Length = 511 Score = 30.0 bits (66), Expect = 5.1 Identities = 20/69 (28%), Positives = 30/69 (43%) Frame = +1 Query: 97 SSRVGCPRPHCKAIITLAPTTDEIGVATGITSQTGLLAQSIRVTCVNCSSGFIISVQKQK 276 S R GCP T A DE+ +AT + L +RV ++ S G ++ K+ Sbjct: 445 SGRRGCPGA------TFAAAIDELALATLVHKFDFKLPNGVRVEDLDMSEGSGFTIHKKF 498 Query: 277 KYMVAKCPH 303 +V PH Sbjct: 499 PLLVVPTPH 507
>sp|P49735|MCM2_DROME DNA replication licensing factor MCM2 Length = 887 Score = 29.6 bits (65), Expect = 6.7 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 5/64 (7%) Frame = +1 Query: 184 ITSQTGLLAQ--SIRVTCVNCSSGFIIS--VQKQK-KYMVAKCPHCQKNSSIGPYYARVR 348 +T+ TG+L Q I+ CV C G+++ VQ Q + CP CQ S GP+ + Sbjct: 297 VTATTGVLPQLSVIKYDCVKC--GYVLGPFVQSQNTEIKPGSCPECQ---STGPFSINME 351 Query: 349 WIIY 360 +Y Sbjct: 352 QTLY 355
>sp|P30328|COAT_PBCV1 Major capsid protein (VP54) Length = 437 Score = 29.3 bits (64), Expect = 8.8 Identities = 13/32 (40%), Positives = 19/32 (59%), Gaps = 1/32 (3%) Frame = +3 Query: 519 NKHYGNFIINYSIILRFNHDNYNC-LITDFVN 611 +KHY ++ Y + R N D YN +TD+VN Sbjct: 106 DKHYNDWFRTYDALFRMNDDRYNYRRMTDWVN 137
>sp|Q9NWF9|UB7I1_HUMAN E3 ubiquitin ligase TRIAD3 (Ubiquitin conjugating enzyme 7 interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) Length = 866 Score = 29.3 bits (64), Expect = 8.8 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Frame = +1 Query: 10 REATPIKAAPPGKKYVRC-TCNGLLICKSSSSRVGCPRPHCK 132 R+A AA + VRC +C+ + S R CP PHC+ Sbjct: 588 RKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCR 629
>sp|Q7UKT6|SURE_RHOBA 5'-nucleotidase surE (Nucleoside 5'-monophosphate phosphohydrolase) Length = 253 Score = 29.3 bits (64), Expect = 8.8 Identities = 14/32 (43%), Positives = 20/32 (62%) Frame = +1 Query: 124 HCKAIITLAPTTDEIGVATGITSQTGLLAQSI 219 H +IT+AP T++ GV IT T L+ +SI Sbjct: 25 HLGEVITVAPATEQSGVGHSITYLTPLVPKSI 56
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 68,660,552 Number of Sequences: 369166 Number of extensions: 1358981 Number of successful extensions: 3085 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2991 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3080 length of database: 68,354,980 effective HSP length: 106 effective length of database: 48,773,070 effective search space used: 5072399280 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)