Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_L21
(627 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9GP32|ALF_ECHMU Fructose-bisphosphate aldolase 209 4e-54
sp|P53442|ALF_SCHMA Fructose-bisphosphate aldolase 199 6e-51
sp|P07764|ALF_DROME Fructose-bisphosphate aldolase 197 2e-50
sp|P53446|ALF2_LAMJA Fructose-bisphosphate aldolase, non-mu... 196 4e-50
sp|P05064|ALDOA_MOUSE Fructose-bisphosphate aldolase A (Mus... 192 8e-49
sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A (Mus... 192 8e-49
sp|P05065|ALDOA_RAT Fructose-bisphosphate aldolase A (Muscl... 192 8e-49
sp|P00883|ALDOA_RABIT Fructose-bisphosphate aldolase A (Mus... 192 8e-49
sp|Q9GKW3|ALDOC_MACFA Fructose-bisphosphate aldolase C (Bra... 191 1e-48
sp|P09972|ALDOC_HUMAN Fructose-bisphosphate aldolase C (Bra... 191 1e-48
>sp|Q9GP32|ALF_ECHMU Fructose-bisphosphate aldolase
Length = 363
Score = 209 bits (533), Expect = 4e-54
Identities = 102/151 (67%), Positives = 117/151 (77%)
Frame = +3
Query: 3 DPILARNISGVILYHETLHQKGDDGQPLVKYLQDRGIIPGIKVDTGCVPLLGTFDECTTQ 182
DP A++ISGVIL+HET++QK DG+P V+ L++RG++PGIKVD G VPL GT DECTTQ
Sbjct: 67 DPEFAKHISGVILFHETVYQKTKDGKPFVELLRERGVLPGIKVDLGVVPLGGTADECTTQ 126
Query: 183 GLDGLDERCAIYKKDGCHFAKWRCVLKIGQHTPSYLAMIENANVLARYAMICQKNGLVPI 362
GLD L +RCA Y DGC FAKWRCVLKI H PSYLAM+ENANVLARYA ICQ+NGLVPI
Sbjct: 127 GLDNLAQRCAQYYNDGCRFAKWRCVLKISSHNPSYLAMLENANVLARYAFICQQNGLVPI 186
Query: 363 VEPEVLPDGTHDFVHGSASN*GCIKHFVYKA 455
VEPEVLPDG HD + FVYKA
Sbjct: 187 VEPEVLPDGDHDLETAQRVT-EQVLSFVYKA 216
Score = 71.2 bits (173), Expect = 2e-12
Identities = 39/76 (51%), Positives = 48/76 (63%)
Frame = +1
Query: 400 LFTAQRVTEDVLSILYTKLLADHHIYLEGTLLKPNMVTAGMQSPRKYLSGTKCTSNC*GF 579
L TAQRVTE VLS +Y K LADHH+YLEGTLLKPNMVT G +KY +
Sbjct: 199 LETAQRVTEQVLSFVY-KALADHHVYLEGTLLKPNMVTCGQSCTKKYSVEDNARATVEAL 257
Query: 580 YEKSTSLQFPGITFLS 627
+++ + PG+ FLS
Sbjct: 258 -QRTVPVAVPGVVFLS 272
>sp|P53442|ALF_SCHMA Fructose-bisphosphate aldolase
Length = 363
Score = 199 bits (505), Expect = 6e-51
Identities = 103/151 (68%), Positives = 112/151 (74%)
Frame = +3
Query: 3 DPILARNISGVILYHETLHQKGDDGQPLVKYLQDRGIIPGIKVDTGCVPLLGTFDECTTQ 182
D LA NISGVIL+ ETLHQK DDG+ L L +R IIPGIKVD G VPL GT +E TTQ
Sbjct: 67 DHKLAENISGVILFEETLHQKSDDGKTLPTLLAERNIIPGIKVDKGVVPLAGTDNETTTQ 126
Query: 183 GLDGLDERCAIYKKDGCHFAKWRCVLKIGQHTPSYLAMIENANVLARYAMICQKNGLVPI 362
GLD L RCA Y + GC FAKWRCVLKI HTPSYLAM+ENANVLARYA ICQ+NGLVPI
Sbjct: 127 GLDDLASRCAEYWRLGCRFAKWRCVLKISSHTPSYLAMLENANVLARYASICQQNGLVPI 186
Query: 363 VEPEVLPDGTHDFVHGSASN*GCIKHFVYKA 455
VEPEVLPDG HD + + FVYKA
Sbjct: 187 VEPEVLPDGDHDLLTAQRVT-EQVLAFVYKA 216
Score = 71.6 bits (174), Expect = 2e-12
Identities = 40/76 (52%), Positives = 48/76 (63%)
Frame = +1
Query: 400 LFTAQRVTEDVLSILYTKLLADHHIYLEGTLLKPNMVTAGMQSPRKYLSGTKCTSNC*GF 579
L TAQRVTE VL+ +Y K LADHH+YLEGTLLKPNMVTAG + Y +
Sbjct: 199 LLTAQRVTEQVLAFVY-KALADHHVYLEGTLLKPNMVTAGQACKKAYTPQENALATVRAL 257
Query: 580 YEKSTSLQFPGITFLS 627
+++ PGITFLS
Sbjct: 258 -QRTVPPAVPGITFLS 272
>sp|P07764|ALF_DROME Fructose-bisphosphate aldolase
Length = 361
Score = 197 bits (501), Expect = 2e-50
Identities = 95/132 (71%), Positives = 107/132 (81%)
Frame = +3
Query: 3 DPILARNISGVILYHETLHQKGDDGQPLVKYLQDRGIIPGIKVDTGCVPLLGTFDECTTQ 182
DP LA NISGVIL+HETL+QK DDG P + L+ +GII GIKVD G VPL G+ DE TTQ
Sbjct: 67 DPKLAENISGVILFHETLYQKADDGTPFAEILKKKGIILGIKVDKGVVPLFGSEDEVTTQ 126
Query: 183 GLDGLDERCAIYKKDGCHFAKWRCVLKIGQHTPSYLAMIENANVLARYAMICQKNGLVPI 362
GLD L RCA YKKDGC FAKWRCVLKIG++TPSY +++ENANVLARYA ICQ +VPI
Sbjct: 127 GLDDLAARCAQYKKDGCDFAKWRCVLKIGKNTPSYQSILENANVLARYASICQSQRIVPI 186
Query: 363 VEPEVLPDGTHD 398
VEPEVLPDG HD
Sbjct: 187 VEPEVLPDGDHD 198
Score = 59.3 bits (142), Expect = 8e-09
Identities = 31/43 (72%), Positives = 37/43 (86%)
Frame = +1
Query: 409 AQRVTEDVLSILYTKLLADHHIYLEGTLLKPNMVTAGMQSPRK 537
AQ+VTE VL+ +Y K L+DHH+YLEGTLLKPNMVTAG QS +K
Sbjct: 202 AQKVTETVLAAVY-KALSDHHVYLEGTLLKPNMVTAG-QSAKK 242
>sp|P53446|ALF2_LAMJA Fructose-bisphosphate aldolase, non-muscle type
Length = 364
Score = 196 bits (498), Expect = 4e-50
Identities = 95/132 (71%), Positives = 106/132 (80%)
Frame = +3
Query: 3 DPILARNISGVILYHETLHQKGDDGQPLVKYLQDRGIIPGIKVDTGCVPLLGTFDECTTQ 182
DP + + I GVI Y ETL+QK DDG P VK ++DRGI+ GIKVD G VPL GT E TTQ
Sbjct: 67 DPSVTKAIGGVIFYEETLYQKTDDGTPFVKLIKDRGIVVGIKVDKGTVPLAGTDGESTTQ 126
Query: 183 GLDGLDERCAIYKKDGCHFAKWRCVLKIGQHTPSYLAMIENANVLARYAMICQKNGLVPI 362
GLDGL ERCA YKKDG FAKWRCVLKI ++TPS LA+ ENANVLARYA ICQ+NGLVPI
Sbjct: 127 GLDGLAERCARYKKDGADFAKWRCVLKISKNTPSALAIAENANVLARYASICQQNGLVPI 186
Query: 363 VEPEVLPDGTHD 398
VEPE+LPDG HD
Sbjct: 187 VEPEILPDGDHD 198
Score = 59.3 bits (142), Expect = 8e-09
Identities = 37/76 (48%), Positives = 46/76 (60%)
Frame = +1
Query: 400 LFTAQRVTEDVLSILYTKLLADHHIYLEGTLLKPNMVTAGMQSPRKYLSGTKCTSNC*GF 579
L T Q VTE VL+ Y K L+DHH+YLEG+LLKPNMVTAG Q+ + S +
Sbjct: 199 LKTCQYVTEKVLAATY-KALSDHHVYLEGSLLKPNMVTAG-QASKIRCSPQEVAMATVTA 256
Query: 580 YEKSTSLQFPGITFLS 627
++ PGITFLS
Sbjct: 257 LRRTVPSAVPGITFLS 272
>sp|P05064|ALDOA_MOUSE Fructose-bisphosphate aldolase A (Muscle-type aldolase) (Aldolase
1)
Length = 364
Score = 192 bits (487), Expect = 8e-49
Identities = 90/125 (72%), Positives = 104/125 (83%)
Frame = +3
Query: 24 ISGVILYHETLHQKGDDGQPLVKYLQDRGIIPGIKVDTGCVPLLGTFDECTTQGLDGLDE 203
I GVIL+HETL+QK DDG+P + ++ +G + GIKVD G VPL GT E TTQGLDGL E
Sbjct: 74 IGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSE 133
Query: 204 RCAIYKKDGCHFAKWRCVLKIGQHTPSYLAMIENANVLARYAMICQKNGLVPIVEPEVLP 383
RCA YKKDG FAKWRCVLKIG+HTPS LA++ENANVLARYA ICQ+NG+VPIVEPE+LP
Sbjct: 134 RCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILP 193
Query: 384 DGTHD 398
DG HD
Sbjct: 194 DGDHD 198
Score = 55.5 bits (132), Expect = 1e-07
Identities = 33/72 (45%), Positives = 43/72 (59%)
Frame = +1
Query: 412 QRVTEDVLSILYTKLLADHHIYLEGTLLKPNMVTAGMQSPRKYLSGTKCTSNC*GFYEKS 591
Q VTE VL+ +Y K L+DHH+YLEGTLLKPNMVT G +K+ S + ++
Sbjct: 203 QYVTEKVLAAVY-KALSDHHVYLEGTLLKPNMVTPGHACTQKF-SNEEIAMATVTALRRT 260
Query: 592 TSLQFPGITFLS 627
G+TFLS
Sbjct: 261 VPPAVTGVTFLS 272
>sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A (Muscle-type aldolase) (Lung
cancer antigen NY-LU-1)
Length = 364
Score = 192 bits (487), Expect = 8e-49
Identities = 90/125 (72%), Positives = 104/125 (83%)
Frame = +3
Query: 24 ISGVILYHETLHQKGDDGQPLVKYLQDRGIIPGIKVDTGCVPLLGTFDECTTQGLDGLDE 203
I GVIL+HETL+QK DDG+P + ++ +G + GIKVD G VPL GT E TTQGLDGL E
Sbjct: 74 IGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSE 133
Query: 204 RCAIYKKDGCHFAKWRCVLKIGQHTPSYLAMIENANVLARYAMICQKNGLVPIVEPEVLP 383
RCA YKKDG FAKWRCVLKIG+HTPS LA++ENANVLARYA ICQ+NG+VPIVEPE+LP
Sbjct: 134 RCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILP 193
Query: 384 DGTHD 398
DG HD
Sbjct: 194 DGDHD 198
Score = 55.5 bits (132), Expect = 1e-07
Identities = 35/72 (48%), Positives = 43/72 (59%)
Frame = +1
Query: 412 QRVTEDVLSILYTKLLADHHIYLEGTLLKPNMVTAGMQSPRKYLSGTKCTSNC*GFYEKS 591
Q VTE VL+ +Y K L+DHHIYLEGTLLKPNMVT G +K+ S + ++
Sbjct: 203 QYVTEKVLAAVY-KALSDHHIYLEGTLLKPNMVTPGHACTQKF-SHEEIAMATVTALRRT 260
Query: 592 TSLQFPGITFLS 627
GITFLS
Sbjct: 261 VPPAVTGITFLS 272
>sp|P05065|ALDOA_RAT Fructose-bisphosphate aldolase A (Muscle-type aldolase)
Length = 364
Score = 192 bits (487), Expect = 8e-49
Identities = 90/125 (72%), Positives = 104/125 (83%)
Frame = +3
Query: 24 ISGVILYHETLHQKGDDGQPLVKYLQDRGIIPGIKVDTGCVPLLGTFDECTTQGLDGLDE 203
I GVIL+HETL+QK DDG+P + ++ +G + GIKVD G VPL GT E TTQGLDGL E
Sbjct: 74 IGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSE 133
Query: 204 RCAIYKKDGCHFAKWRCVLKIGQHTPSYLAMIENANVLARYAMICQKNGLVPIVEPEVLP 383
RCA YKKDG FAKWRCVLKIG+HTPS LA++ENANVLARYA ICQ+NG+VPIVEPE+LP
Sbjct: 134 RCAQYKKDGADFAKWRCVLKIGEHTPSSLAIMENANVLARYASICQQNGIVPIVEPEILP 193
Query: 384 DGTHD 398
DG HD
Sbjct: 194 DGDHD 198
Score = 58.5 bits (140), Expect = 1e-08
Identities = 34/72 (47%), Positives = 44/72 (61%)
Frame = +1
Query: 412 QRVTEDVLSILYTKLLADHHIYLEGTLLKPNMVTAGMQSPRKYLSGTKCTSNC*GFYEKS 591
Q VTE VL+ +Y K L+DHH+YLEGTLLKPNMVT G +K+ S + ++
Sbjct: 203 QYVTEKVLAAVY-KALSDHHVYLEGTLLKPNMVTPGHACTQKF-SNEEIAMATVTALRRT 260
Query: 592 TSLQFPGITFLS 627
PG+TFLS
Sbjct: 261 VPPAVPGVTFLS 272
>sp|P00883|ALDOA_RABIT Fructose-bisphosphate aldolase A (Muscle-type aldolase)
Length = 364
Score = 192 bits (487), Expect = 8e-49
Identities = 90/125 (72%), Positives = 104/125 (83%)
Frame = +3
Query: 24 ISGVILYHETLHQKGDDGQPLVKYLQDRGIIPGIKVDTGCVPLLGTFDECTTQGLDGLDE 203
I GVIL+HETL+QK DDG+P + ++ +G + GIKVD G VPL GT E TTQGLDGL E
Sbjct: 74 IGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSE 133
Query: 204 RCAIYKKDGCHFAKWRCVLKIGQHTPSYLAMIENANVLARYAMICQKNGLVPIVEPEVLP 383
RCA YKKDG FAKWRCVLKIG+HTPS LA++ENANVLARYA ICQ+NG+VPIVEPE+LP
Sbjct: 134 RCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILP 193
Query: 384 DGTHD 398
DG HD
Sbjct: 194 DGDHD 198
Score = 56.6 bits (135), Expect = 5e-08
Identities = 29/43 (67%), Positives = 33/43 (76%)
Frame = +1
Query: 412 QRVTEDVLSILYTKLLADHHIYLEGTLLKPNMVTAGMQSPRKY 540
Q VTE VL+ +Y K L+DHHIYLEGTLLKPNMVT G +KY
Sbjct: 203 QYVTEKVLAAVY-KALSDHHIYLEGTLLKPNMVTPGHACTQKY 244
>sp|Q9GKW3|ALDOC_MACFA Fructose-bisphosphate aldolase C (Brain-type aldolase)
Length = 364
Score = 191 bits (486), Expect = 1e-48
Identities = 91/132 (68%), Positives = 106/132 (80%)
Frame = +3
Query: 3 DPILARNISGVILYHETLHQKGDDGQPLVKYLQDRGIIPGIKVDTGCVPLLGTFDECTTQ 182
D + + I GVI +HETL+QK D+G P V+ +QD+GI+ GIKVD G VPL GT E TTQ
Sbjct: 67 DDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGIVVGIKVDKGVVPLAGTDGETTTQ 126
Query: 183 GLDGLDERCAIYKKDGCHFAKWRCVLKIGQHTPSYLAMIENANVLARYAMICQKNGLVPI 362
GLDGL ERCA YKKDG FAKWRCVLKI + TPS LA++ENANVLARYA ICQ+NG+VPI
Sbjct: 127 GLDGLSERCAQYKKDGADFAKWRCVLKISERTPSALAILENANVLARYASICQQNGIVPI 186
Query: 363 VEPEVLPDGTHD 398
VEPE+LPDG HD
Sbjct: 187 VEPEILPDGDHD 198
Score = 60.5 bits (145), Expect = 3e-09
Identities = 35/72 (48%), Positives = 43/72 (59%)
Frame = +1
Query: 412 QRVTEDVLSILYTKLLADHHIYLEGTLLKPNMVTAGMQSPRKYLSGTKCTSNC*GFYEKS 591
Q VTE VL+ +Y K L+DHH+YLEGTLLKPNMVT G P KY + ++
Sbjct: 203 QYVTEKVLAAVY-KALSDHHVYLEGTLLKPNMVTPGHACPIKYTPEEIAMATVTAL-RRT 260
Query: 592 TSLQFPGITFLS 627
PG+TFLS
Sbjct: 261 VPPAVPGVTFLS 272
>sp|P09972|ALDOC_HUMAN Fructose-bisphosphate aldolase C (Brain-type aldolase)
Length = 364
Score = 191 bits (486), Expect = 1e-48
Identities = 91/132 (68%), Positives = 106/132 (80%)
Frame = +3
Query: 3 DPILARNISGVILYHETLHQKGDDGQPLVKYLQDRGIIPGIKVDTGCVPLLGTFDECTTQ 182
D + + I GVI +HETL+QK D+G P V+ +QD+GI+ GIKVD G VPL GT E TTQ
Sbjct: 67 DDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGIVVGIKVDKGVVPLAGTDGETTTQ 126
Query: 183 GLDGLDERCAIYKKDGCHFAKWRCVLKIGQHTPSYLAMIENANVLARYAMICQKNGLVPI 362
GLDGL ERCA YKKDG FAKWRCVLKI + TPS LA++ENANVLARYA ICQ+NG+VPI
Sbjct: 127 GLDGLSERCAQYKKDGADFAKWRCVLKISERTPSALAILENANVLARYASICQQNGIVPI 186
Query: 363 VEPEVLPDGTHD 398
VEPE+LPDG HD
Sbjct: 187 VEPEILPDGDHD 198
Score = 60.5 bits (145), Expect = 3e-09
Identities = 35/72 (48%), Positives = 43/72 (59%)
Frame = +1
Query: 412 QRVTEDVLSILYTKLLADHHIYLEGTLLKPNMVTAGMQSPRKYLSGTKCTSNC*GFYEKS 591
Q VTE VL+ +Y K L+DHH+YLEGTLLKPNMVT G P KY + ++
Sbjct: 203 QYVTEKVLAAVY-KALSDHHVYLEGTLLKPNMVTPGHACPIKYTPEEIAMATVTAL-RRT 260
Query: 592 TSLQFPGITFLS 627
PG+TFLS
Sbjct: 261 VPPAVPGVTFLS 272
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,129,782
Number of Sequences: 369166
Number of extensions: 1740445
Number of successful extensions: 4129
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3961
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4096
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 4974853140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)