Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_L06
(945 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P50440|GATM_HUMAN Glycine amidinotransferase, mitochondr... 222 1e-57
sp|P50441|GATM_PIG Glycine amidinotransferase (L-arginine:g... 220 4e-57
sp|Q9D964|GATM_MOUSE Glycine amidinotransferase, mitochondr... 218 2e-56
sp|P50442|GATM_RAT Glycine amidinotransferase, mitochondria... 216 6e-56
sp|P08078|STRB1_STRGR Inosamine-phosphate amidinotransferas... 104 4e-22
sp|P29780|STRB2_STRGR Putative inosamine-phosphate amidinot... 98 4e-20
sp|Q54258|STRB1_STRGA Inosamine-phosphate amidinotransferas... 97 5e-20
sp|Q54264|STRB2_STRGA Putative inosamine-phosphate amidinot... 57 8e-08
sp|Q5HCR2|ARCA_STAAC Arginine deiminase (ADI) (Arginine dih... 33 1.5
sp|Q6GDG7|ARCA_STAAR Arginine deiminase (ADI) (Arginine dih... 33 1.5
>sp|P50440|GATM_HUMAN Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 222 bits (565), Expect = 1e-57
Identities = 132/299 (44%), Positives = 178/299 (59%), Gaps = 8/299 (2%)
Frame = +2
Query: 62 SKFNRILTLNCVYKTSVSTNQIVLSNITHRNCCT---KTKVENKKNSPVWSWNEWDPLEE 232
S+ R LT V +T ST S+ RN C K K+ PV S+NEWDPLEE
Sbjct: 22 SRLGRTLT-GWVQRTFQSTQAATASS---RNSCAADDKATEPLPKDCPVSSYNEWDPLEE 77
Query: 233 VIXXXXXXXXXXXXXXETAACFGERLTENFMKKYGGQYWSDIMPKEVWQNVLKEHQEFVN 412
VI E A E+ F +K GG Y+ PK+ + + E +E N
Sbjct: 78 VIVGRAENACVPPFTIEVKANTYEKYWP-FYQKQGGHYF----PKDHLKKAVAEIEEMCN 132
Query: 413 ILKGEGVKVVHPEPMDMKKEYETPYFKSVGLDCAFPRDIILVVGDEIMETTMTWRSRFWE 592
ILK EGV V P+P+D +Y+TP F+S GL A PRDI++VVG+EI+E M WRSRF+E
Sbjct: 133 ILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFE 192
Query: 593 YLCYRPLMLDYWRRGANFQSAPKPVCSEQSFKKNFDISG----NKFDELG-YVTTEFEPM 757
Y YR ++ DY+ RGA + +APKP +++ + +++ I +K G +VTTEFEP
Sbjct: 193 YRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPC 252
Query: 758 FDAADFMRAGRDIFVQQSHVTNASGIEWMRQHLAEKGIRLHLLNFHDPYAMHMMQRFSL 934
FDAADF+RAGRDIF Q+S VTN GIEWMR+HLA R+H+++F DP MH+ F++
Sbjct: 253 FDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLA-PDYRVHIISFKDPNPMHIDATFNI 310
>sp|P50441|GATM_PIG Glycine amidinotransferase (L-arginine:glycine amidinotransferase)
(Transamidinase) (AT)
Length = 386
Score = 220 bits (561), Expect = 4e-57
Identities = 120/255 (47%), Positives = 164/255 (64%), Gaps = 5/255 (1%)
Frame = +2
Query: 185 KNSPVWSWNEWDPLEEVIXXXXXXXXXXXXXXETAACFGERLTENFMKKYGGQYWSDIMP 364
K+ PV S+NEWDPLEEVI E A E+ F +KYGG Y+ P
Sbjct: 25 KDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWP-FYQKYGGHYF----P 79
Query: 365 KEVWQNVLKEHQEFVNILKGEGVKVVHPEPMDMKKEYETPYFKSVGLDCAFPRDIILVVG 544
K+ + + E +E NILK EGV V P+P+D +Y+TP F+S GL A PRDI++VVG
Sbjct: 80 KDHLKKAVAEIEEMCNILKMEGVTVRRPDPIDWSVKYKTPDFESTGLYGAMPRDILIVVG 139
Query: 545 DEIMETTMTWRSRFWEYLCYRPLMLDYWRRGANFQSAPKPVCSEQSFKKNFDI----SGN 712
+EI+E M WR+RF+EY YR ++ DY+RRGA + +APKP +++ + +++ I +
Sbjct: 140 NEIIEAPMAWRARFFEYRAYRSIIKDYFRRGAKWTTAPKPTMADELYDQDYPIYSVEDRH 199
Query: 713 KFDELG-YVTTEFEPMFDAADFMRAGRDIFVQQSHVTNASGIEWMRQHLAEKGIRLHLLN 889
K G +VTTEFEP FDAADF+RAGRDIF Q+S VTN GIEWMR+HLA R+H+++
Sbjct: 200 KLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYMGIEWMRKHLA-PDYRVHIIS 258
Query: 890 FHDPYAMHMMQRFSL 934
F DP MH+ F++
Sbjct: 259 FKDPNPMHIDATFNI 273
>sp|Q9D964|GATM_MOUSE Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 218 bits (555), Expect = 2e-56
Identities = 126/287 (43%), Positives = 173/287 (60%), Gaps = 7/287 (2%)
Frame = +2
Query: 95 VYKTSVSTNQIVLSNITHRNCCTKTKVENK--KNSPVWSWNEWDPLEEVIXXXXXXXXXX 268
V +T ST S+ +C + K + K+ PV S+NEWDPLEEVI
Sbjct: 32 VQRTFQSTQAATASS--RNSCAAEDKATHPLPKDCPVSSYNEWDPLEEVIVGRAENACVP 89
Query: 269 XXXXETAACFGERLTENFMKKYGGQYWSDIMPKEVWQNVLKEHQEFVNILKGEGVKVVHP 448
E A E+ F +K GG Y+ PK+ + + E +E NIL EGV V P
Sbjct: 90 PFTVEVKANTYEKYWP-FYQKNGGLYF----PKDHLKKAVAEVEEMCNILSMEGVTVRRP 144
Query: 449 EPMDMKKEYETPYFKSVGLDCAFPRDIILVVGDEIMETTMTWRSRFWEYLCYRPLMLDYW 628
+P+D +Y+TP F+S GL A PRDI++VVG+EI+E M WRSRF+EY YR ++ DY+
Sbjct: 145 DPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYF 204
Query: 629 RRGANFQSAPKPVCSEQSFKKNFDISG----NKFDELG-YVTTEFEPMFDAADFMRAGRD 793
RGA + +APKP +++ + +N+ I +K G +VTTEFEP FDAADF+RAGRD
Sbjct: 205 HRGAKWTTAPKPTMADELYDQNYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRD 264
Query: 794 IFVQQSHVTNASGIEWMRQHLAEKGIRLHLLNFHDPYAMHMMQRFSL 934
IF Q+S VTN GIEWMR+HLA R+H+++F DP MH+ F++
Sbjct: 265 IFAQRSQVTNYLGIEWMRRHLA-PDYRVHIISFKDPNPMHIDATFNI 310
>sp|P50442|GATM_RAT Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 216 bits (551), Expect = 6e-56
Identities = 125/287 (43%), Positives = 173/287 (60%), Gaps = 7/287 (2%)
Frame = +2
Query: 95 VYKTSVSTNQIVLSNITHRNCCTKTKVENK--KNSPVWSWNEWDPLEEVIXXXXXXXXXX 268
V +T ST S+ +C + K + K+ PV S+NEWDPLEEVI
Sbjct: 32 VQRTFQSTQAATASS--QNSCAAEDKATHPLPKDCPVSSYNEWDPLEEVIVGRAENACVP 89
Query: 269 XXXXETAACFGERLTENFMKKYGGQYWSDIMPKEVWQNVLKEHQEFVNILKGEGVKVVHP 448
E A E+ F +K GG Y+ PK+ + + E +E NIL EGV V P
Sbjct: 90 PFTVEVKANTYEKYWP-FYQKNGGLYF----PKDHLKKAVAEVEEMCNILSMEGVTVKRP 144
Query: 449 EPMDMKKEYETPYFKSVGLDCAFPRDIILVVGDEIMETTMTWRSRFWEYLCYRPLMLDYW 628
+P+D +Y+TP F+S GL A PRDI++VVG+EI+E M WRSRF+EY YR ++ DY+
Sbjct: 145 DPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYF 204
Query: 629 RRGANFQSAPKPVCSEQSFKKNFDISG----NKFDELG-YVTTEFEPMFDAADFMRAGRD 793
RGA + +APKP +++ + +++ I +K G +VTTEFEP FDAADF+RAGRD
Sbjct: 205 HRGAKWTTAPKPTMADELYDQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRD 264
Query: 794 IFVQQSHVTNASGIEWMRQHLAEKGIRLHLLNFHDPYAMHMMQRFSL 934
IF Q+S VTN GIEWMR+HLA R+H+++F DP MH+ F++
Sbjct: 265 IFAQRSQVTNYLGIEWMRRHLA-PDYRVHIISFKDPNPMHIDATFNI 310
>sp|P08078|STRB1_STRGR Inosamine-phosphate amidinotransferase I (Aminocyclitol
amidinotransferase) (ADT)
Length = 347
Score = 104 bits (259), Expect = 4e-22
Identities = 76/228 (33%), Positives = 110/228 (48%), Gaps = 10/228 (4%)
Frame = +2
Query: 209 NEWDPLEEVIXXXXXXXXXXXXXXETAACFGERLTEN----FMKKYGGQYWS-DIMPKEV 373
NEWDPLEEVI G R+ F +Y G Y S + +P
Sbjct: 8 NEWDPLEEVI---------------VGTAVGARVPTADRSVFAVEYAGDYESQEQIPSGA 52
Query: 374 WQN-VLKEHQEFVNILKGE----GVKVVHPEPMDMKKEYETPYFKSVGLDCAFPRDIILV 538
+ + VLKE +E +++L E GV V P P D +TP +++ G PRD +L
Sbjct: 53 YPDRVLKETEEELHVLAAELTKLGVTVRRPGPRDHSALIKTPDWETDGFHDYCPRDGLLS 112
Query: 539 VGDEIMETTMTWRSRFWEYLCYRPLMLDYWRRGANFQSAPKPVCSEQSFKKNFDISGNKF 718
VG I+ET M RSRF E L Y+ L+L+Y+ G+ + SAPKP ++ S+
Sbjct: 113 VGQTIIETPMALRSRFLESLAYKDLLLEYFASGSRWLSAPKPRLTDDSYAPQAPAGERLT 172
Query: 719 DELGYVTTEFEPMFDAADFMRAGRDIFVQQSHVTNASGIEWMRQHLAE 862
DE EP+FDAA+ +R G D+ S N G +W++ + +
Sbjct: 173 DE--------EPVFDAANVLRFGTDLLYLVSDSGNELGAKWLQSAVGD 212
>sp|P29780|STRB2_STRGR Putative inosamine-phosphate amidinotransferase II (Aminocyclitol
amidinotransferase) (ADT)
Length = 349
Score = 97.8 bits (242), Expect = 4e-20
Identities = 70/223 (31%), Positives = 101/223 (45%), Gaps = 7/223 (3%)
Frame = +2
Query: 209 NEWDPLEEVIXXXXXXXXXXXXXXETAACFG---ERLTENFMKKYGGQYWSDI----MPK 367
NEWDPLEEV+ C G L + + G W ++ P
Sbjct: 8 NEWDPLEEVVVGTARRP-----------CAGPDRSLLAVEYAEYAGPGRWQEVPTGPYPD 56
Query: 368 EVWQNVLKEHQEFVNILKGEGVKVVHPEPMDMKKEYETPYFKSVGLDCAFPRDIILVVGD 547
+ E +E L+G GV V P D TP ++S G PRD +LVVGD
Sbjct: 57 RALKETEDELEELCEELRGLGVTVRRPGARDSAAPVRTPDWESDGYGDLCPRDGLLVVGD 116
Query: 548 EIMETTMTWRSRFWEYLCYRPLMLDYWRRGANFQSAPKPVCSEQSFKKNFDISGNKFDEL 727
++E M R+RF E L Y+ L+++Y G+ + SAPKP +E + + SG + +L
Sbjct: 117 TVIEAPMALRARFLESLAYKELLVEYLAAGSRWISAPKPRLAEGMYSPS-GPSGERLRDL 175
Query: 728 GYVTTEFEPMFDAADFMRAGRDIFVQQSHVTNASGIEWMRQHL 856
EP+FDAA+ +R G D+ S N G W++ L
Sbjct: 176 -------EPVFDAANVLRLGTDLLYLVSDSGNELGARWLQSAL 211
>sp|Q54258|STRB1_STRGA Inosamine-phosphate amidinotransferase I (Aminocyclitol
amidinotransferase) (ADT)
Length = 348
Score = 97.4 bits (241), Expect = 5e-20
Identities = 71/226 (31%), Positives = 109/226 (48%), Gaps = 10/226 (4%)
Frame = +2
Query: 209 NEWDPLEEVIXXXXXXXXXXXXXXETAACFGERLTEN----FMKKYGGQYWS-DIMPKEV 373
NEWDPLEE+I G R+ F +Y +Y S D +P
Sbjct: 8 NEWDPLEEII---------------VGTAVGARVPRADRSVFAVEYADEYDSQDQVPAGP 52
Query: 374 WQN-VLKEHQEFVNILKGE----GVKVVHPEPMDMKKEYETPYFKSVGLDCAFPRDIILV 538
+ + VLKE +E +++L E GV V P D TP +++ G PRD +L
Sbjct: 53 YPDRVLKETEEELHVLSEELTKLGVTVRRPGQRDNSALVATPDWQTDGFHDYCPRDGLLA 112
Query: 539 VGDEIMETTMTWRSRFWEYLCYRPLMLDYWRRGANFQSAPKPVCSEQSFKKNFDISGNKF 718
VG ++E+ M R+RF E L Y+ ++L+Y+ GA + SAPKP +++ ++
Sbjct: 113 VGQTVIESPMALRARFLESLAYKDILLEYFASGARWLSAPKPRLADEMYEPT-------- 164
Query: 719 DELGYVTTEFEPMFDAADFMRAGRDIFVQQSHVTNASGIEWMRQHL 856
G T+ EP+FDAA+ +R G D+ S N G +W++ L
Sbjct: 165 APAGQRLTDLEPVFDAANVLRFGTDLLYLVSDSGNELGAKWLQSAL 210
>sp|Q54264|STRB2_STRGA Putative inosamine-phosphate amidinotransferase II (Aminocyclitol
amidinotransferase) (ADT)
Length = 319
Score = 57.0 bits (136), Expect = 8e-08
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 3/153 (1%)
Frame = +2
Query: 416 LKGEGVKVVHPEPMDMKKEYETPYFKSVGLDCAF---PRDIILVVGDEIMETTMTWRSRF 586
L+G GV V P D P G D A PRD +L VG+ +++T
Sbjct: 43 LRGLGVTVRRLPPQDPASPPAPP---DRGADTALAYRPRDGLLTVGETVIQTPAVPGLPS 99
Query: 587 WEYLCYRPLMLDYWRRGANFQSAPKPVCSEQSFKKNFDISGNKFDELGYVTTEFEPMFDA 766
+ R L+++Y+ G+ + SAP PV + D+ + G E EP+FDA
Sbjct: 100 LQSPACRMLLMEYFTSGSRWISAPPPVLT--------DVMYDPTAPAGERLRELEPVFDA 151
Query: 767 ADFMRAGRDIFVQQSHVTNASGIEWMRQHLAEK 865
+R G D+ S NA G W++ L E+
Sbjct: 152 DTVLRIGTDLLYLVSDSGNALGARWLQAALGER 184
>sp|Q5HCR2|ARCA_STAAC Arginine deiminase (ADI) (Arginine dihydrolase) (AD)
sp|Q8NUK7|ARCA_STAAW Arginine deiminase (ADI) (Arginine dihydrolase) (AD)
sp|Q6G639|ARCA_STAAS Arginine deiminase (ADI) (Arginine dihydrolase) (AD)
Length = 411
Score = 32.7 bits (73), Expect = 1.5
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 314 ENFMKKY-GGQYWSDIMPKEVWQNVLKEHQEFVNILKGEGVKVVHPEPMDMKKEYETPYF 490
EN + Y G + DI EV Q KEH F +L+ EGV+V++ E + + E P
Sbjct: 28 ENLVPDYLDGLLFDDIPYLEVAQ---KEHDHFAQVLREEGVEVLYLEKL-AAESIENPQV 83
Query: 491 KSVGLDCAFPRDIILVVGDE 550
+S +D ++G E
Sbjct: 84 RSEFIDDVLAESKKTILGHE 103
>sp|Q6GDG7|ARCA_STAAR Arginine deiminase (ADI) (Arginine dihydrolase) (AD)
Length = 411
Score = 32.7 bits (73), Expect = 1.5
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 314 ENFMKKY-GGQYWSDIMPKEVWQNVLKEHQEFVNILKGEGVKVVHPEPMDMKKEYETPYF 490
EN + Y G + DI EV Q KEH F +L+ EGV+V++ E + + E P
Sbjct: 28 ENLVPDYLDGLLFDDIPYLEVAQ---KEHDHFAQVLREEGVEVLYLEKL-AAESIENPQV 83
Query: 491 KSVGLDCAFPRDIILVVGDE 550
+S +D ++G E
Sbjct: 84 RSEFIDDVLAESKKTILGHE 103
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 115,384,425
Number of Sequences: 369166
Number of extensions: 2503131
Number of successful extensions: 6257
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6035
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6234
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9798962520
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)