Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_L01
(822 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q969Q5|RAB24_HUMAN Ras-related protein Rab-24 191 2e-48
sp|P35290|RAB24_MOUSE Ras-related protein Rab-24 (Rab-16) 187 4e-47
sp|P36586|YPT5_SCHPO Ras-related protein ypt5 115 1e-25
sp|P36019|YPT53_YEAST GTP-binding protein YPT53 110 6e-24
sp|Q9UL26|RB22A_HUMAN Ras-related protein Rab-22A (Rab-22) 108 2e-23
sp|P41925|RYL2_YARLI Ras-like GTP-binding protein RYL2 106 9e-23
sp|P35285|RB22A_MOUSE Ras-related protein Rab-22A (Rab-22) ... 106 9e-23
sp|P51154|RB22A_CANFA Ras-related protein Rab-22A (Rab-22) 106 9e-23
sp|Q6GQP4|RAB31_RAT Ras-related protein Rab-31 (GTP-binding... 105 1e-22
sp|Q921E2|RAB31_MOUSE Ras-related protein Rab-31 105 2e-22
>sp|Q969Q5|RAB24_HUMAN Ras-related protein Rab-24
Length = 203
Score = 191 bits (485), Expect = 2e-48
Identities = 90/200 (45%), Positives = 140/200 (70%)
Frame = +2
Query: 89 SPPKVDIKVVVLGKEFVGKTALVERFLYDNFSSNSYQPTIGAAYGARQIKNKNNVPIVMG 268
S +VD+KVV+LGKE+VGKT+LVER+++D F YQ TIGAA+ A+ + + + + +G
Sbjct: 2 SGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAK-VMSVGDRTVTLG 60
Query: 269 IWDTAGSERYQSMTKMYYRNAKAAILCYDMCDSVSFKRLDYWVQELRNTEPDCLIFICGC 448
IWDTAGSERY++M+++YYR AKAAI+CYD+ DS SF+R +WV+ELR+ E C I++CG
Sbjct: 61 IWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGT 120
Query: 449 KKDLIQANKNQRAVNEYIVNEFATSLNAKVYETSSKTAEGIVKLFEDICNDVSDNPSFLS 628
K DL++ ++ +R V+ + V ++A ++ A+++ETSSKT + + +LF+ + D +F
Sbjct: 121 KSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQV 180
Query: 629 DTMKKNIELDNKPKNNISIC 688
T K ++L KP C
Sbjct: 181 MTEDKGVDLGQKPNPYFYSC 200
>sp|P35290|RAB24_MOUSE Ras-related protein Rab-24 (Rab-16)
Length = 203
Score = 187 bits (474), Expect = 4e-47
Identities = 88/192 (45%), Positives = 137/192 (71%)
Frame = +2
Query: 89 SPPKVDIKVVVLGKEFVGKTALVERFLYDNFSSNSYQPTIGAAYGARQIKNKNNVPIVMG 268
S +VD+KVV+LGKE+VGKT+LVER+++D F YQ TIGAA+ A+ + + + +G
Sbjct: 2 SGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAK-VMCVGDRTVTLG 60
Query: 269 IWDTAGSERYQSMTKMYYRNAKAAILCYDMCDSVSFKRLDYWVQELRNTEPDCLIFICGC 448
IWDTAGSERY++M+++YYR AKAAI+CYD+ DS SF+R +WV+ELR+ E C I++CG
Sbjct: 61 IWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGT 120
Query: 449 KKDLIQANKNQRAVNEYIVNEFATSLNAKVYETSSKTAEGIVKLFEDICNDVSDNPSFLS 628
K DL++ ++ +R V+ + V ++A ++ A+++ETSSKT + + +LF+ + D +F
Sbjct: 121 KSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQV 180
Query: 629 DTMKKNIELDNK 664
T K ++L K
Sbjct: 181 MTEDKGVDLSQK 192
>sp|P36586|YPT5_SCHPO Ras-related protein ypt5
Length = 211
Score = 115 bits (289), Expect = 1e-25
Identities = 66/170 (38%), Positives = 100/170 (58%), Gaps = 1/170 (0%)
Frame = +2
Query: 86 KSPPKVDIKVVVLGKEFVGKTALVERFLYDNFSSNSYQPTIGAAYGARQIKNKNNVPIVM 265
K+ ++ K+V+LG VGK++LV RF+ D F + TIGAA+ + + N + +
Sbjct: 8 KNVVTINQKLVLLGDSAVGKSSLVLRFVKDQFDDYR-ESTIGAAFLTQTLPIDENTSVKL 66
Query: 266 GIWDTAGSERYQSMTKMYYRNAKAAILCYDMCDSVSFKRLDYWVQELRNTEPD-CLIFIC 442
IWDTAG ERY+S+ MYYRNA AI+ YD+ + S ++ W++EL+ P+ +I +
Sbjct: 67 EIWDTAGQERYKSLAPMYYRNANCAIVVYDITQAASLEKAKSWIKELQRQAPEGIVIALA 126
Query: 443 GCKKDLIQANKNQRAVNEYIVNEFATSLNAKVYETSSKTAEGIVKLFEDI 592
G K DL Q +RAV + +A N +ETS+KTAE + +LF I
Sbjct: 127 GNKLDLAQ---ERRAVEKADAEAYAAEANLLFFETSAKTAENVNELFTAI 173
>sp|P36019|YPT53_YEAST GTP-binding protein YPT53
Length = 220
Score = 110 bits (274), Expect = 6e-24
Identities = 65/169 (38%), Positives = 98/169 (57%), Gaps = 3/169 (1%)
Frame = +2
Query: 95 PKVDIKVVVLGKEFVGKTALVERFLYDNFSSNSYQPTIGAAYGARQIKNKNNVPIVMGIW 274
P + IKVV+LG+ VGK+++V RF+ D+F S +PTIGAA+ ++I V I IW
Sbjct: 9 PTLTIKVVLLGESAVGKSSIVLRFVSDDFKE-SKEPTIGAAFLTKRITRDGKV-IKFEIW 66
Query: 275 DTAGSERYQSMTKMYYRNAKAAILCYDMCDSVSFKRLDYWVQEL-RNTEPDCLIFICGCK 451
DTAG ER+ + MYYRNA+AA++ +D+ + SF + WV+EL D +I + G K
Sbjct: 67 DTAGQERFAPLAPMYYRNAQAALVVFDVTNEGSFYKAQNWVEELHEKVGHDIVIALVGNK 126
Query: 452 KDLIQAN--KNQRAVNEYIVNEFATSLNAKVYETSSKTAEGIVKLFEDI 592
DL+ + RA+ V N +E S+KT E I ++F+ +
Sbjct: 127 MDLLNNDDENENRAMKAPAVQNLCERENLLYFEASAKTGENIYQIFQTL 175
>sp|Q9UL26|RB22A_HUMAN Ras-related protein Rab-22A (Rab-22)
Length = 194
Score = 108 bits (270), Expect = 2e-23
Identities = 65/164 (39%), Positives = 101/164 (61%), Gaps = 1/164 (0%)
Frame = +2
Query: 104 DIKVVVLGKEFVGKTALVERFLYDNFSSNSYQPTIGAAYGARQIKNKNNVPIVMGIWDTA 283
++KV +LG VGK+++V RF+ D+F N PTIGA++ + ++ +N + + IWDTA
Sbjct: 5 ELKVCLLGDTGVGKSSIVWRFVEDSFDPN-INPTIGASFMTKTVQYQNELHKFL-IWDTA 62
Query: 284 GSERYQSMTKMYYRNAKAAILCYDMCDSVSFKRLDYWVQELR-NTEPDCLIFICGCKKDL 460
G ER++++ MYYR + AAI+ YD+ +F L WV+ELR + P+ ++ I G K DL
Sbjct: 63 GQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVKELRQHGPPNIVVAIAGNKCDL 122
Query: 461 IQANKNQRAVNEYIVNEFATSLNAKVYETSSKTAEGIVKLFEDI 592
I R V E ++A S++A ETS+K A I +LF +I
Sbjct: 123 IDV----REVMERDAKDYADSIHAIFVETSAKNAININELFIEI 162
>sp|P41925|RYL2_YARLI Ras-like GTP-binding protein RYL2
Length = 209
Score = 106 bits (264), Expect = 9e-23
Identities = 62/174 (35%), Positives = 100/174 (57%), Gaps = 4/174 (2%)
Frame = +2
Query: 101 VDIKVVVLGKEFVGKTALVERFLYDNFSSNSYQPTIGAAYGARQIKNKNNVPIVMGIWDT 280
+D K+V+LG + VGKT V R++ + F + TIGA++ +++ N+ + + IWDT
Sbjct: 4 MDAKIVLLGAQGVGKTCFVTRYVNNKFQAGQAS-TIGASFSRKRVV-VNDTTVRLQIWDT 61
Query: 281 AGSERYQSMTKMYYRNAKAAILCYDMCDSVSFKRLDYWVQELR-NTEPDCLIFICGCKKD 457
AG ER++SM +YYR+A ILCYD+ SF + W+ EL+ N D +I I G K D
Sbjct: 62 AGQERFRSMAPIYYRSASCGILCYDVTSRASFDAMHLWLLELKQNLSSDIIIHIVGTKVD 121
Query: 458 LIQANKNQRAVNEYIVNEFATSL---NAKVYETSSKTAEGIVKLFEDICNDVSD 610
L++ + R V E+A+ ++ +E S+K EG+ ++FE I + D
Sbjct: 122 LVKDEPSLREVPFEQCVEYASEWLQDDSCCHEISAKDDEGVEEVFEVIITKLLD 175
>sp|P35285|RB22A_MOUSE Ras-related protein Rab-22A (Rab-22) (Rab-14)
Length = 194
Score = 106 bits (264), Expect = 9e-23
Identities = 64/164 (39%), Positives = 99/164 (60%), Gaps = 1/164 (0%)
Frame = +2
Query: 104 DIKVVVLGKEFVGKTALVERFLYDNFSSNSYQPTIGAAYGARQIKNKNNVPIVMGIWDTA 283
++KV +LG VGK+++V RF+ D+F N PTIGA++ + ++ +N + + IWDTA
Sbjct: 5 ELKVCLLGDTGVGKSSIVWRFVEDSFDPN-INPTIGASFMTKTVQYQNELHKFL-IWDTA 62
Query: 284 GSERYQSMTKMYYRNAKAAILCYDMCDSVSFKRLDYWVQELR-NTEPDCLIFICGCKKDL 460
G ER++++ MYYR + AAI+ YD+ +F L WV+ELR + P ++ I G K DL
Sbjct: 63 GQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNKCDL 122
Query: 461 IQANKNQRAVNEYIVNEFATSLNAKVYETSSKTAEGIVKLFEDI 592
R V E ++A S++A ETS+K A I +LF +I
Sbjct: 123 TDV----REVMERDAKDYADSIHAIFVETSAKNAININELFIEI 162
>sp|P51154|RB22A_CANFA Ras-related protein Rab-22A (Rab-22)
Length = 194
Score = 106 bits (264), Expect = 9e-23
Identities = 64/164 (39%), Positives = 100/164 (60%), Gaps = 1/164 (0%)
Frame = +2
Query: 104 DIKVVVLGKEFVGKTALVERFLYDNFSSNSYQPTIGAAYGARQIKNKNNVPIVMGIWDTA 283
++KV +LG VGK+++V RF+ D+F N PTIGA++ + ++ +N + + IWDTA
Sbjct: 5 ELKVCLLGDTGVGKSSIVWRFVEDSFDPN-INPTIGASFMTKTVQYQNELHKFL-IWDTA 62
Query: 284 GSERYQSMTKMYYRNAKAAILCYDMCDSVSFKRLDYWVQELR-NTEPDCLIFICGCKKDL 460
G E ++++ MYYR + AAI+ YD+ +F L WV+ELR + P+ ++ I G K DL
Sbjct: 63 GQEAFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVKELRQHGPPNIVVAIAGNKCDL 122
Query: 461 IQANKNQRAVNEYIVNEFATSLNAKVYETSSKTAEGIVKLFEDI 592
I R V E ++A S++A ETS+K A I +LF +I
Sbjct: 123 IDV----REVMERDAKDYADSIHAIFVETSAKNAININELFIEI 162
>sp|Q6GQP4|RAB31_RAT Ras-related protein Rab-31 (GTP-binding protein Rab0)
Length = 194
Score = 105 bits (262), Expect = 1e-22
Identities = 65/168 (38%), Positives = 97/168 (57%), Gaps = 1/168 (0%)
Frame = +2
Query: 104 DIKVVVLGKEFVGKTALVERFLYDNFSSNSYQPTIGAAYGARQIKNKNNVPIVMGIWDTA 283
++KV +LG VGK+++V RF+ D+F N PTIGA++ + + N + + IWDTA
Sbjct: 5 ELKVCLLGDTGVGKSSIVCRFVQDHFDHN-ISPTIGASFMTKTVPCGNELHKFL-IWDTA 62
Query: 284 GSERYQSMTKMYYRNAKAAILCYDMCDSVSFKRLDYWVQELRNTEPDCLIF-ICGCKKDL 460
G ER+ S+ MYYR + AA++ YD+ SF L WV+EL+ P+ ++ I G K DL
Sbjct: 63 GQERFHSLAPMYYRGSAAAVIVYDITKQDSFHTLKKWVKELKEHGPENIVMAIAGNKCDL 122
Query: 461 IQANKNQRAVNEYIVNEFATSLNAKVYETSSKTAEGIVKLFEDICNDV 604
+ R V E+A S+ A V ETS+K A I +LF+ I +
Sbjct: 123 ----SDIREVPLKDAKEYAESIGALVVETSAKNAINIEELFQGISRQI 166
>sp|Q921E2|RAB31_MOUSE Ras-related protein Rab-31
Length = 194
Score = 105 bits (261), Expect = 2e-22
Identities = 65/168 (38%), Positives = 97/168 (57%), Gaps = 1/168 (0%)
Frame = +2
Query: 104 DIKVVVLGKEFVGKTALVERFLYDNFSSNSYQPTIGAAYGARQIKNKNNVPIVMGIWDTA 283
++KV +LG VGK+++V RF+ D+F N PTIGA++ + + N + + IWDTA
Sbjct: 5 ELKVCLLGDTGVGKSSIVCRFVQDHFDHN-ISPTIGASFMTKTVPCGNELHKFL-IWDTA 62
Query: 284 GSERYQSMTKMYYRNAKAAILCYDMCDSVSFKRLDYWVQELRNTEPDCLIF-ICGCKKDL 460
G ER+ S+ MYYR + AA++ YD+ SF L WV+EL+ P+ ++ I G K DL
Sbjct: 63 GQERFHSLAPMYYRGSAAAVIVYDITKQDSFHTLKKWVKELKEHGPENIVMAIAGNKCDL 122
Query: 461 IQANKNQRAVNEYIVNEFATSLNAKVYETSSKTAEGIVKLFEDICNDV 604
+ R V E+A S+ A V ETS+K A I +LF+ I +
Sbjct: 123 ----SDIREVPLKDAKEYAESIGAIVVETSAKNAINIEELFQGISRQI 166
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,190,142
Number of Sequences: 369166
Number of extensions: 1740896
Number of successful extensions: 4920
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4417
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4558
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7907893860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)