Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_J23
(566 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P24156|L2CC_DROME L(2)37Cc protein 197 2e-50
sp|P67778|PHB_MOUSE Prohibitin (B-cell receptor associated ... 192 5e-49
sp|P35232|PHB_HUMAN Prohibitin 191 1e-48
sp|P40961|PHB_YEAST Prohibitin 179 4e-45
sp|Q9BKU4|PHB1_CAEEL Mitochondrial prohibitin complex prote... 175 6e-44
sp|O35129|PHB2_MOUSE Prohibitin-2 (B-cell receptor-associat... 155 7e-38
sp|Q5XIH7|PHB2_RAT Prohibitin-2 (B-cell receptor-associated... 155 7e-38
sp|P50085|PHB2_YEAST Prohibitin-2 154 1e-37
sp|P50093|PHB2_CAEEL Mitochondrial prohibitin complex prote... 139 4e-33
sp|Q58237|Y827_METJA Hypothetical protein MJ0827 40 0.005
>sp|P24156|L2CC_DROME L(2)37Cc protein
Length = 276
Score = 197 bits (500), Expect = 2e-50
Identities = 98/152 (64%), Positives = 117/152 (76%)
Frame = +1
Query: 22 FFIPWIQRPIIYDIRTRPRNIPVNTGSKDLQKVNITLRILYKPVAEMLPKIYTNLGLDFE 201
FFIPW+QRPII+DIR++PRN+PV TGSKDLQ VNITLRILY+P+ + LPKIYT LG D++
Sbjct: 56 FFIPWVQRPIIFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYD 115
Query: 202 ERVLPSITYEVLKTVVAQFDASDLITQRELVSQKVNEMLTTRADNFGLTLDDIFLTHLTF 381
ERVLPSI EVLK VVAQFDA +LITQRE+VSQ+V++ LT RA FG LDDI LTHLTF
Sbjct: 116 ERVLPSIAPEVLKAVVAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTF 175
Query: 382 GSEFSXXXXXXXXXXXXXXXXXYLVEKAEQEK 477
G EF+ ++VEKAEQ+K
Sbjct: 176 GREFTLAVEMKQVAQQEAEKARFVVEKAEQQK 207
>sp|P67778|PHB_MOUSE Prohibitin (B-cell receptor associated protein 32) (BAP 32)
sp|P67779|PHB_RAT Prohibitin
Length = 272
Score = 192 bits (488), Expect = 5e-49
Identities = 94/152 (61%), Positives = 119/152 (78%)
Frame = +1
Query: 22 FFIPWIQRPIIYDIRTRPRNIPVNTGSKDLQKVNITLRILYKPVAEMLPKIYTNLGLDFE 201
F IPW+Q+PII+D R+RPRN+PV TGSKDLQ VNITLRIL++PVA LP+IYT++G D++
Sbjct: 56 FLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYD 115
Query: 202 ERVLPSITYEVLKTVVAQFDASDLITQRELVSQKVNEMLTTRADNFGLTLDDIFLTHLTF 381
ERVLPSIT E+LK+VVA+FDA +LITQRELVS++V++ LT RA FGL LDD+ LTHLTF
Sbjct: 116 ERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTF 175
Query: 382 GSEFSXXXXXXXXXXXXXXXXXYLVEKAEQEK 477
G EF+ ++VEKAEQ+K
Sbjct: 176 GKEFTEAVEAKQVAQQEAERARFVVEKAEQQK 207
>sp|P35232|PHB_HUMAN Prohibitin
Length = 272
Score = 191 bits (484), Expect = 1e-48
Identities = 93/152 (61%), Positives = 119/152 (78%)
Frame = +1
Query: 22 FFIPWIQRPIIYDIRTRPRNIPVNTGSKDLQKVNITLRILYKPVAEMLPKIYTNLGLDFE 201
F IPW+Q+PII+D R+RPRN+PV TGSKDLQ VNITLRIL++PVA LP+I+T++G D++
Sbjct: 56 FLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYD 115
Query: 202 ERVLPSITYEVLKTVVAQFDASDLITQRELVSQKVNEMLTTRADNFGLTLDDIFLTHLTF 381
ERVLPSIT E+LK+VVA+FDA +LITQRELVS++V++ LT RA FGL LDD+ LTHLTF
Sbjct: 116 ERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTF 175
Query: 382 GSEFSXXXXXXXXXXXXXXXXXYLVEKAEQEK 477
G EF+ ++VEKAEQ+K
Sbjct: 176 GKEFTEAVEAKQVAQQEAERARFVVEKAEQQK 207
>sp|P40961|PHB_YEAST Prohibitin
Length = 287
Score = 179 bits (454), Expect = 4e-45
Identities = 83/152 (54%), Positives = 116/152 (76%)
Frame = +1
Query: 22 FFIPWIQRPIIYDIRTRPRNIPVNTGSKDLQKVNITLRILYKPVAEMLPKIYTNLGLDFE 201
F +PW+Q+ IIYD+RT+P++I NTG+KDLQ V++TLR+L++P LP IY NLGLD++
Sbjct: 58 FLVPWLQKAIIYDVRTKPKSIATNTGTKDLQMVSLTLRVLHRPEVLQLPAIYQNLGLDYD 117
Query: 202 ERVLPSITYEVLKTVVAQFDASDLITQRELVSQKVNEMLTTRADNFGLTLDDIFLTHLTF 381
ERVLPSI EVLK++VAQFDA++LITQRE++SQK+ + L+TRA+ FG+ L+D+ +TH+TF
Sbjct: 118 ERVLPSIGNEVLKSIVAQFDAAELITQREIISQKIRKELSTRANEFGIKLEDVSITHMTF 177
Query: 382 GSEFSXXXXXXXXXXXXXXXXXYLVEKAEQEK 477
G EF+ +LVEKAEQE+
Sbjct: 178 GPEFTKAVEQKQIAQQDAERAKFLVEKAEQER 209
>sp|Q9BKU4|PHB1_CAEEL Mitochondrial prohibitin complex protein 1 (Prohibitin-1)
Length = 275
Score = 175 bits (444), Expect = 6e-44
Identities = 90/152 (59%), Positives = 107/152 (70%)
Frame = +1
Query: 22 FFIPWIQRPIIYDIRTRPRNIPVNTGSKDLQKVNITLRILYKPVAEMLPKIYTNLGLDFE 201
F IPW+Q+PII+DIR+ PR + TGSKDLQ VNITLRIL++P + LP IY N+GLD+
Sbjct: 59 FLIPWVQKPIIFDIRSTPRAVTTITGSKDLQNVNITLRILHRPSPDRLPNIYLNIGLDYA 118
Query: 202 ERVLPSITYEVLKTVVAQFDASDLITQRELVSQKVNEMLTTRADNFGLTLDDIFLTHLTF 381
ERVLPSIT EVLK VVAQFDA ++ITQRE+VSQ+ + L RA FGL LDDI +THL F
Sbjct: 119 ERVLPSITNEVLKAVVAQFDAHEMITQREVVSQRASVALRERAAQFGLLLDDIAITHLNF 178
Query: 382 GSEFSXXXXXXXXXXXXXXXXXYLVEKAEQEK 477
G EF+ YLVEKAEQ K
Sbjct: 179 GREFTEAVEMKQVAQQEAEKARYLVEKAEQMK 210
>sp|O35129|PHB2_MOUSE Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor
of estrogen receptor activity)
sp|Q99623|PHB2_HUMAN Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor
of estrogen receptor activity) (D-prohibitin)
Length = 299
Score = 155 bits (392), Expect = 7e-38
Identities = 83/152 (54%), Positives = 102/152 (67%)
Frame = +1
Query: 22 FFIPWIQRPIIYDIRTRPRNIPVNTGSKDLQKVNITLRILYKPVAEMLPKIYTNLGLDFE 201
F IPW Q PIIYDIR RPR I TGSKDLQ VNI+LR+L +P A+ LP +Y LGLD+E
Sbjct: 70 FRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYE 129
Query: 202 ERVLPSITYEVLKTVVAQFDASDLITQRELVSQKVNEMLTTRADNFGLTLDDIFLTHLTF 381
ERVLPSI EVLK+VVA+F+AS LITQR VS + LT RA +F L LDD+ +T L+F
Sbjct: 130 ERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSF 189
Query: 382 GSEFSXXXXXXXXXXXXXXXXXYLVEKAEQEK 477
E++ +LVEKA+QE+
Sbjct: 190 SREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQ 221
>sp|Q5XIH7|PHB2_RAT Prohibitin-2 (B-cell receptor-associated protein BAP37) (BAP-37)
Length = 299
Score = 155 bits (392), Expect = 7e-38
Identities = 83/152 (54%), Positives = 102/152 (67%)
Frame = +1
Query: 22 FFIPWIQRPIIYDIRTRPRNIPVNTGSKDLQKVNITLRILYKPVAEMLPKIYTNLGLDFE 201
F IPW Q PIIYDIR RPR I TGSKDLQ VNI+LR+L +P A+ LP +Y LGLD+E
Sbjct: 70 FRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYE 129
Query: 202 ERVLPSITYEVLKTVVAQFDASDLITQRELVSQKVNEMLTTRADNFGLTLDDIFLTHLTF 381
ERVLPSI EVLK+VVA+F+AS LITQR VS + LT RA +F L LDD+ +T L+F
Sbjct: 130 ERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSF 189
Query: 382 GSEFSXXXXXXXXXXXXXXXXXYLVEKAEQEK 477
E++ +LVEKA+QE+
Sbjct: 190 SREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQ 221
>sp|P50085|PHB2_YEAST Prohibitin-2
Length = 315
Score = 154 bits (389), Expect = 1e-37
Identities = 78/154 (50%), Positives = 99/154 (64%)
Frame = +1
Query: 22 FFIPWIQRPIIYDIRTRPRNIPVNTGSKDLQKVNITLRILYKPVAEMLPKIYTNLGLDFE 201
F PW+ PIIYD+R +PRN+ TG+KDLQ VNIT R+L +P LP IY LG D++
Sbjct: 87 FIFPWLDTPIIYDVRAKPRNVASLTGTKDLQMVNITCRVLSRPDVVQLPTIYRTLGQDYD 146
Query: 202 ERVLPSITYEVLKTVVAQFDASDLITQRELVSQKVNEMLTTRADNFGLTLDDIFLTHLTF 381
ERVLPSI EVLK VVAQF+AS LITQRE VS+ + E L RA F + LDD+ +T++TF
Sbjct: 147 ERVLPSIVNEVLKAVVAQFNASQLITQREKVSRLIRENLVRRASKFNILLDDVSITYMTF 206
Query: 382 GSEFSXXXXXXXXXXXXXXXXXYLVEKAEQEKFG 483
EF+ ++V+KA QEK G
Sbjct: 207 SPEFTNAVEAKQIAQQDAQRAAFVVDKARQEKQG 240
>sp|P50093|PHB2_CAEEL Mitochondrial prohibitin complex protein 2 (Prohibitin-2)
Length = 286
Score = 139 bits (351), Expect = 4e-33
Identities = 81/159 (50%), Positives = 99/159 (62%), Gaps = 1/159 (0%)
Frame = +1
Query: 4 LVKEHIFF-IPWIQRPIIYDIRTRPRNIPVNTGSKDLQKVNITLRILYKPVAEMLPKIYT 180
L KE + F IPW Q PIIYDIR RP I TGSKDLQ VNI LR+L +P E L IY
Sbjct: 54 LYKEGLHFRIPWFQYPIIYDIRARPNQIRSPTGSKDLQMVNIGLRVLSRPNPEHLVHIYR 113
Query: 181 NLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSQKVNEMLTTRADNFGLTLDDI 360
LG ++EERVLPSI EVLK VVA+F+AS LITQR+ VS V + L RA +F + LDD+
Sbjct: 114 TLGQNWEERVLPSICNEVLKGVVAKFNASQLITQRQQVSMLVRKTLIERALDFNIILDDV 173
Query: 361 FLTHLTFGSEFSXXXXXXXXXXXXXXXXXYLVEKAEQEK 477
LT L F ++S + VE+A+Q+K
Sbjct: 174 SLTELAFSPQYSAAVEAKQVAAQEAQRATFYVERAKQQK 212
>sp|Q58237|Y827_METJA Hypothetical protein MJ0827
Length = 199
Score = 39.7 bits (91), Expect = 0.005
Identities = 25/112 (22%), Positives = 58/112 (51%), Gaps = 1/112 (0%)
Frame = +1
Query: 28 IPWIQRPIIYDIRTRPRNIPVNTG-SKDLQKVNITLRILYKPVAEMLPKIYTNLGLDFEE 204
IP++ P+ D+RTR +IP +KD V + + Y+ V ++ I L ++ E
Sbjct: 54 IPFLDVPVKVDMRTRVTDIPPQEMITKDNAVVKVDAVVYYR-VIDVEKAI---LEVEDYE 109
Query: 205 RVLPSITYEVLKTVVAQFDASDLITQRELVSQKVNEMLTTRADNFGLTLDDI 360
+ ++ L+ ++ + +++ +RE ++ K+ E+L D +G+ ++ +
Sbjct: 110 YAIINLAQTTLRAIIGSMELDEVLNKREYINSKLLEILDRETDAWGVRIEKV 161
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,367,674
Number of Sequences: 369166
Number of extensions: 1028029
Number of successful extensions: 2333
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2294
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2331
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4127973360
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)