Planarian EST Database


Dr_sW_014_J20

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_014_J20
         (731 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q02445|TFPI1_RAT  Tissue factor pathway inhibitor precurs...    82   2e-15
sp|Q28864|TFPI1_MACMU  Tissue factor pathway inhibitor precu...    81   3e-15
sp|Q03610|YN81_CAEEL  Hypothetical protein ZC84.1 in chromos...    80   6e-15
sp|P10646|TFPI1_HUMAN  Tissue factor pathway inhibitor precu...    77   5e-14
sp|P19761|TFPI1_RABIT  Tissue factor pathway inhibitor precu...    74   4e-13
sp|O54819|TFPI1_MOUSE  Tissue factor pathway inhibitor precu...    72   1e-12
sp|O35536|TFPI2_MOUSE  Tissue factor pathway inhibitor 2 pre...    68   2e-11
sp|P48307|TFPI2_HUMAN  Tissue factor pathway inhibitor 2 pre...    63   9e-10
sp|Q9WU03|SPIT2_MOUSE  Kunitz-type protease inhibitor 2 prec...    60   8e-09
sp|O43291|SPIT2_HUMAN  Kunitz-type protease inhibitor 2 prec...    60   8e-09
>sp|Q02445|TFPI1_RAT Tissue factor pathway inhibitor precursor (TFPI)
           (Lipoprotein-associated coagulation inhibitor) (LACI)
           (Extrinsic pathway inhibitor) (EPI)
          Length = 302

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 48/148 (32%), Positives = 66/148 (44%), Gaps = 10/148 (6%)
 Frame = +1

Query: 61  CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
           C    T YFY+     C  F+Y GC G+ NNF T   C  TC + VN +   +K      
Sbjct: 133 CRGFMTRYFYNNQSKQCEQFKYGGCLGNSNNFETLEECRNTCEDPVNEV---QKGDYVTN 189

Query: 241 QFQSQSSSDKRKKMPTMADQCRLEVKYGGM----------YCNSTKYEIRYYYDNRNGRC 390
           Q      +     +   A +   +  Y G            C ++  E R+YY+   G+C
Sbjct: 190 QITVTDRTTVNNVVIPQATKAPSQWDYDGPSWCLEPADSGLCKAS--EKRFYYNPAIGKC 247

Query: 391 RQFTFTGCDGNSNNFPTYHGCIKACMPD 474
           RQF +TGC GN+NNF T   C +AC  D
Sbjct: 248 RQFNYTGCGGNNNNFTTKQDCNRACKKD 275

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 56/197 (28%), Positives = 85/197 (43%), Gaps = 26/197 (13%)
 Frame = +1

Query: 61  CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
           C     +Y+++ + H C  F Y GC+G+ N F T   C KTC+      P ++K  +   
Sbjct: 62  CKAMIRSYYFNMNSHQCEEFIYGGCRGNKNRFDTLEECRKTCI------PGYKKTTI--- 112

Query: 241 QFQSQSSSDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDG 420
             ++ S ++K        D C LE   G   C    +  RY+Y+N++ +C QF + GC G
Sbjct: 113 --KTTSGAEK-------PDFCFLEEDPG--ICRG--FMTRYFYNNQSKQCEQFKYGGCLG 159

Query: 421 NSNNFPTYHGCIKAC------------MPDQIDFMKTAPIKPCLV-------SEWSHWGP 543
           NSNNF T   C   C            + +QI       +   ++       S+W + GP
Sbjct: 160 NSNNFETLEECRNTCEDPVNEVQKGDYVTNQITVTDRTTVNNVVIPQATKAPSQWDYDGP 219

Query: 544 C-------SSLCGAGEK 573
                   S LC A EK
Sbjct: 220 SWCLEPADSGLCKASEK 236
>sp|Q28864|TFPI1_MACMU Tissue factor pathway inhibitor precursor (TFPI)
           (Lipoprotein-associated coagulation inhibitor) (LACI)
           (Extrinsic pathway inhibitor) (EPI)
          Length = 304

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 5/140 (3%)
 Frame = +1

Query: 61  CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
           C    T YFY+     C  F+Y GC G++NNF T   C+ TC + +N       +    L
Sbjct: 134 CRGYITRYFYNNQSKQCERFKYGGCLGNMNNFETLEECKNTCEDGLNGFQV--DNYGTQL 191

Query: 241 QFQSQSSSDKRKKMPTMAD-----QCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTF 405
              + S + +  K+P+  +      C      G    N    E R+YY++  G+CR F +
Sbjct: 192 NAVNNSQTPQSTKVPSFFEFHGPSWCLAPADRGLCRAN----ENRFYYNSVIGKCRPFKY 247

Query: 406 TGCDGNSNNFPTYHGCIKAC 465
           +GC GN NNF +   C++AC
Sbjct: 248 SGCGGNENNFTSKRECLRAC 267

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 39/128 (30%), Positives = 56/128 (43%)
 Frame = +1

Query: 82  YFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHLQFQSQSS 261
           +F++     C  F Y GC G+ N F +   C+K C           +D + H   Q+   
Sbjct: 70  FFFNIFTRQCEEFIYGGCGGNQNRFESMEECKKVC----------TRDNV-HRIIQTALQ 118

Query: 262 SDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDGNSNNFPT 441
            +K        D C LE   G   C    Y  RY+Y+N++ +C +F + GC GN NNF T
Sbjct: 119 QEK-------PDFCFLEEDPG--ICRG--YITRYFYNNQSKQCERFKYGGCLGNMNNFET 167

Query: 442 YHGCIKAC 465
              C   C
Sbjct: 168 LEECKNTC 175

 Score = 37.7 bits (86), Expect = 0.032
 Identities = 13/41 (31%), Positives = 22/41 (53%)
 Frame = +1

Query: 358 RYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPDQI 480
           R++++    +C +F + GC GN N F +   C K C  D +
Sbjct: 69  RFFFNIFTRQCEEFIYGGCGGNQNRFESMEECKKVCTRDNV 109
>sp|Q03610|YN81_CAEEL Hypothetical protein ZC84.1 in chromosome III
          Length = 1416

 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 54/175 (30%), Positives = 74/175 (42%), Gaps = 20/175 (11%)
 Frame = +1

Query: 1   DTALCDP--VIICSEGLVIGSKCGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVC 174
           D  +C P    IC++ L IG  C      Y+Y+A    C  FEY GC+G+ NNF + M C
Sbjct: 422 DQGVCCPRKQTICAQPLRIGD-CTENVKRYWYNARTRQCQMFEYTGCQGNDNNFDSIMDC 480

Query: 175 EKTCLEAVNALP-------QWRKDKMAHL-----------QFQSQSSSDKRKKMPTMADQ 300
           +  C    NA+P       Q  KD   +             ++      +    PT A  
Sbjct: 481 QNFC---KNAIPEPKCIQGQAYKDMFGNFVTCSNGMGCPANYECYFDGSQWGCCPTKAFT 537

Query: 301 CRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKAC 465
           C L     G+ C +     +YYY+ +   C  F + GCDGNSNNF     C   C
Sbjct: 538 CSLNTD-SGIQCGAGS-TFKYYYNPQTQNCESFQYNGCDGNSNNFANRDACESYC 590

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 54/180 (30%), Positives = 72/180 (40%), Gaps = 20/180 (11%)
 Frame = +1

Query: 31   CSEGLVIGSKCGNPTT-NYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNAL 207
            CS     G +CG  +T  Y+Y+     C SF+Y GC G+ NNF  +  CE  C  +V   
Sbjct: 538  CSLNTDSGIQCGAGSTFKYYYNPQTQNCESFQYNGCDGNSNNFANRDACESYC--SVGGC 595

Query: 208  PQWRKDKMAHLQF------QSQSSSDKRKKMP-------------TMADQCRLEVKYGGM 330
            P        H         Q  S  D  + +P             T A  C L  + G  
Sbjct: 596  PNGGTPLRDHSGMVMVCGAQQTSCPDSHECIPVLVGNSLINRCCPTRAYMCGLPPQQGTQ 655

Query: 331  YCNSTKYEIRYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPDQIDFMKTAPIKP 510
             C +  Y  RYY++    +C  F F GCDGN+NNF     C   CM +       A + P
Sbjct: 656  -CGAN-YVQRYYFNIVTSQCTSFQFGGCDGNANNFLNIQQCRNFCMSNACPAGNVAYVDP 713

 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 41/142 (28%), Positives = 60/142 (42%), Gaps = 8/142 (5%)
 Frame = +1

Query: 64  GNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTC--LEAVNALPQWRKDKMAH 237
           G  +  ++YD     C  F Y G  G+ NNF +K  CE  C  L+     P    ++   
Sbjct: 347 GKESIRFYYDPGTGRCQDFVYKGAGGNYNNFLSKHECEMYCARLQCERGSPLRIGEEAQR 406

Query: 238 LQFQSQSSSDKRKK------MPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQF 399
            Q  +Q  S    K       P     C   ++ G    + T+   RY+Y+ R  +C+ F
Sbjct: 407 CQNNAQCPSSHECKADQGVCCPRKQTICAQPLRIG----DCTENVKRYWYNARTRQCQMF 462

Query: 400 TFTGCDGNSNNFPTYHGCIKAC 465
            +TGC GN NNF +   C   C
Sbjct: 463 EYTGCQGNDNNFDSIMDCQNFC 484

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 37/136 (27%), Positives = 50/136 (36%), Gaps = 28/136 (20%)
 Frame = +1

Query: 142 SLNNFPTKMVCEKTCLEAVN-ALPQWRKDKMAHLQ---------------FQSQSSSDKR 273
           S NNF T   CE  C +      PQ+  +   H +               FQ  +   + 
Sbjct: 252 SPNNFKTIQHCESYCRDTCQRGSPQYSTESAVHSERPITSCAASVSCANDFQCTAIGSQH 311

Query: 274 KKMPTMADQC------------RLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCD 417
              PT    C            R  + + G    + K  IR+YYD   GRC+ F + G  
Sbjct: 312 LCCPTPGSVCSAKGGRPYDIQPRTSIHHPGFMVYTGKESIRFYYDPGTGRCQDFVYKGAG 371

Query: 418 GNSNNFPTYHGCIKAC 465
           GN NNF + H C   C
Sbjct: 372 GNYNNFLSKHECEMYC 387
>sp|P10646|TFPI1_HUMAN Tissue factor pathway inhibitor precursor (TFPI)
           (Lipoprotein-associated coagulation inhibitor) (LACI)
           (Extrinsic pathway inhibitor) (EPI)
          Length = 304

 Score = 77.0 bits (188), Expect = 5e-14
 Identities = 43/140 (30%), Positives = 66/140 (47%), Gaps = 5/140 (3%)
 Frame = +1

Query: 61  CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
           C    T YFY+     C  F+Y GC G++NNF T   C+  C +  N       +    L
Sbjct: 134 CRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQV--DNYGTQL 191

Query: 241 QFQSQSSSDKRKKMPTMAD-----QCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTF 405
              + S + +  K+P++ +      C      G    N    E R+YY++  G+CR F +
Sbjct: 192 NAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRAN----ENRFYYNSVIGKCRPFKY 247

Query: 406 TGCDGNSNNFPTYHGCIKAC 465
           +GC GN NNF +   C++AC
Sbjct: 248 SGCGGNENNFTSKQECLRAC 267

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 36/128 (28%), Positives = 51/128 (39%)
 Frame = +1

Query: 82  YFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHLQFQSQSS 261
           +F++     C  F Y GC+G+ N F +   C+K C                     + + 
Sbjct: 70  FFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTR------------------DNANR 111

Query: 262 SDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDGNSNNFPT 441
             K        D C LE   G   C    Y  RY+Y+N+  +C +F + GC GN NNF T
Sbjct: 112 IIKTTLQQEKPDFCFLEEDPG--ICRG--YITRYFYNNQTKQCERFKYGGCLGNMNNFET 167

Query: 442 YHGCIKAC 465
              C   C
Sbjct: 168 LEECKNIC 175

 Score = 37.4 bits (85), Expect = 0.041
 Identities = 13/39 (33%), Positives = 22/39 (56%)
 Frame = +1

Query: 358 RYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPD 474
           R++++    +C +F + GC+GN N F +   C K C  D
Sbjct: 69  RFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRD 107
>sp|P19761|TFPI1_RABIT Tissue factor pathway inhibitor precursor (TFPI)
           (Lipoprotein-associated coagulation inhibitor) (LACI)
           (Extrinsic pathway inhibitor) (EPI)
          Length = 300

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 46/142 (32%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
 Frame = +1

Query: 61  CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
           C    T YFY+     C  F+Y GC G+LNNF +   C+ TC    N    ++ D     
Sbjct: 130 CRGYITRYFYNNQSKQCERFKYGGCLGNLNNFESLEECKNTC---ENPTSDFQVDDH--- 183

Query: 241 QFQSQSSSDKRKKMPTMADQCRLEVKYGGMYCNSTK-------YEIRYYYDNRNGRCRQF 399
           + Q  + ++     PT A   R    +G  +C            EIR++Y+   G+CR F
Sbjct: 184 RTQLNTVNNTLINQPTKAP--RRWAFHGPSWCLPPADRGLCQANEIRFFYNAIIGKCRPF 241

Query: 400 TFTGCDGNSNNFPTYHGCIKAC 465
            ++GC GN NNF +   CI AC
Sbjct: 242 KYSGCGGNENNFTSKKACITAC 263

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 41/135 (30%), Positives = 58/135 (42%)
 Frame = +1

Query: 82  YFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHLQFQSQSS 261
           +F++   H C  F Y GC+G+ N F +   C++ C      +          L FQ    
Sbjct: 66  FFFNILTHQCEEFIYGGCEGNENRFESLEECKEKCARDYPKMT-------TKLTFQ---- 114

Query: 262 SDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDGNSNNFPT 441
               K  P   D C LE   G   C    Y  RY+Y+N++ +C +F + GC GN NNF +
Sbjct: 115 ----KGKP---DFCFLEEDPG--ICRG--YITRYFYNNQSKQCERFKYGGCLGNLNNFES 163

Query: 442 YHGCIKACMPDQIDF 486
              C   C     DF
Sbjct: 164 LEECKNTCENPTSDF 178

 Score = 36.6 bits (83), Expect = 0.071
 Identities = 13/42 (30%), Positives = 23/42 (54%)
 Frame = +1

Query: 349 YEIRYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPD 474
           Y  R++++    +C +F + GC+GN N F +   C + C  D
Sbjct: 62  YIKRFFFNILTHQCEEFIYGGCEGNENRFESLEECKEKCARD 103
>sp|O54819|TFPI1_MOUSE Tissue factor pathway inhibitor precursor (TFPI)
           (Lipoprotein-associated coagulation inhibitor) (LACI)
           (Extrinsic pathway inhibitor) (EPI)
          Length = 306

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 43/150 (28%), Positives = 67/150 (44%), Gaps = 15/150 (10%)
 Frame = +1

Query: 61  CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
           C      Y Y+     C  F Y GC G+ NNF T   C+K C   V++     + +M+  
Sbjct: 130 CRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKICENPVHSPSPVNEVQMSDY 189

Query: 241 QFQSQSSSDKRK----------KMPTMADQ-----CRLEVKYGGMYCNSTKYEIRYYYDN 375
                + +D+            K+P   D      C      G   C ++  E R+YY++
Sbjct: 190 VTDGNTVTDRSTVNNIVVPQSPKVPRRRDYRGRPWCLQPADSG--LCKAS--ERRFYYNS 245

Query: 376 RNGRCRQFTFTGCDGNSNNFPTYHGCIKAC 465
             G+C +F +TGC GN+NNF T   C+++C
Sbjct: 246 ATGKCHRFNYTGCGGNNNNFTTRRRCLRSC 275

 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 44/135 (32%), Positives = 63/135 (46%)
 Frame = +1

Query: 61  CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
           C     +YF++   H C  F Y GC+G+ N F T   C+KTC      +P + K  +   
Sbjct: 59  CKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTC------IPGYEKTAV--- 109

Query: 241 QFQSQSSSDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDG 420
             ++ S +++        D C LE   G   C    Y  RY Y+N+  +C +F + GC G
Sbjct: 110 --KAASGAER-------PDFCFLEEDPG--LCRG--YMKRYLYNNQTKQCERFVYGGCLG 156

Query: 421 NSNNFPTYHGCIKAC 465
           N NNF T   C K C
Sbjct: 157 NRNNFETLDECKKIC 171

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 14/37 (37%), Positives = 22/37 (59%)
 Frame = +1

Query: 361 YYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMP 471
           Y+++    +C +F + GC+GN N F T   C K C+P
Sbjct: 66  YFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTCIP 102
>sp|O35536|TFPI2_MOUSE Tissue factor pathway inhibitor 2 precursor (TFPI-2)
          Length = 230

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 42/157 (26%), Positives = 66/157 (42%), Gaps = 28/157 (17%)
 Frame = +1

Query: 82  YFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAH-------- 237
           ++YD  +  C  F Y GC G+ NNF ++ +C++TC       P  R +   +        
Sbjct: 52  FYYDRDQQKCRRFNYGGCLGNANNFHSRDLCQQTCGSIEKVPPVCRSELKTYPCDKPNIR 111

Query: 238 --LQFQSQSSSDKRKKM-----------PTMADQCRLEVKYGGMYCNSTKYE-------I 357
                 + +    R  +            T    C    K+   +C+S K E        
Sbjct: 112 FFFNLNTMTCEPLRPGLCSRTINVFSEEATCKGLCEPR-KHIPSFCSSPKDEGLCSANVT 170

Query: 358 RYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACM 468
           R+Y+++RN  C  FT+TGC GN NNF     C +AC+
Sbjct: 171 RFYFNSRNKTCETFTYTGCGGNENNFYYLDACHRACV 207

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = +1

Query: 358 RYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKAC 465
           ++YYD    +CR+F + GC GN+NNF +   C + C
Sbjct: 51  KFYYDRDQQKCRRFNYGGCLGNANNFHSRDLCQQTC 86

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 14/53 (26%), Positives = 26/53 (49%)
 Frame = +1

Query: 61  CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWR 219
           C    T +++++    C +F Y GC G+ NNF     C + C++      +W+
Sbjct: 165 CSANVTRFYFNSRNKTCETFTYTGCGGNENNFYYLDACHRACVKGWKKPKRWK 217
>sp|P48307|TFPI2_HUMAN Tissue factor pathway inhibitor 2 precursor (TFPI-2) (Placental
           protein 5) (PP5)
          Length = 235

 Score = 62.8 bits (151), Expect = 9e-10
 Identities = 46/166 (27%), Positives = 66/166 (39%), Gaps = 38/166 (22%)
 Frame = +1

Query: 82  YFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKM-------AHL 240
           Y+YD     C  F Y GC+G+ NNF T   C+  C         WR +K+         +
Sbjct: 52  YYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC---------WRIEKVPKVCRLQVSV 102

Query: 241 QFQSQSSSDK----------RKKMPTMADQCRLEVKYGG--------------MYCNSTK 348
             Q + S++K           K       + R+E ++                 +C S K
Sbjct: 103 DDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPK 162

Query: 349 YE-------IRYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKAC 465
            E        RYY++ R   C  FT+TGC GN NNF +   C +AC
Sbjct: 163 DEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
 Frame = +1

Query: 238 LQFQSQSSSDKRKKMPT--MADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTG 411
           L F ++++     + PT   A+ C L + YG   C +    +RYYYD     CRQF + G
Sbjct: 13  LLFLTEAALGDAAQEPTGNNAEICLLPLDYGP--CRALL--LRYYYDRYTQSCRQFLYGG 68

Query: 412 CDGNSNNFPTYHGCIKAC 465
           C+GN+NNF T+  C  AC
Sbjct: 69  CEGNANNFYTWEACDDAC 86

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 22/73 (30%), Positives = 39/73 (53%)
 Frame = +1

Query: 61  CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
           C    T Y+++     C +F Y GC G+ NNF ++  C++ C +A+      +K KM  L
Sbjct: 167 CSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALK-----KKKKMPKL 221

Query: 241 QFQSQSSSDKRKK 279
           +F S+    ++K+
Sbjct: 222 RFASRIRKIRKKQ 234
>sp|Q9WU03|SPIT2_MOUSE Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth
           factor activator inhibitor type 2) (HAI-2)
          Length = 252

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 9/172 (5%)
 Frame = +1

Query: 31  CSEGLVIGSKCGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALP 210
           C    V+G KC      ++Y+ +   C  F Y GC+G+ NN+ +K    + CL+    + 
Sbjct: 38  CGVSKVVG-KCRASIPRWWYNITDGSCQPFVYGGCEGNGNNYQSK----EECLDKCAGVT 92

Query: 211 QWRKDKMAHLQFQSQSS--SDKRKKMPTMADQCRLEVKYGGMYCNSTKYE-------IRY 363
           +   D MA  +  + SS  S  RK+    A+    E+     YC              R+
Sbjct: 93  ENTTDDMARNRNGADSSVLSVPRKQS---AEDLSAEIFNYEEYCVPKAVTGPCRAAFPRW 149

Query: 364 YYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPDQIDFMKTAPIKPCLV 519
           YYD     C  F + GC GN N++ +   C++ C   Q+    T  +K  ++
Sbjct: 150 YYDTEKNSCISFIYGGCRGNKNSYLSQEACMQHCSGKQMHPFLTPGLKAVIL 201
>sp|O43291|SPIT2_HUMAN Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth
           factor activator inhibitor type 2) (HAI-2) (Placental
           bikunin)
          Length = 252

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 39/155 (25%), Positives = 58/155 (37%), Gaps = 6/155 (3%)
 Frame = +1

Query: 31  CSEGLVIGSKCGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVN--- 201
           C    V+G +C      ++Y+ +   C  F Y GC G+ NN+ TK  C K C        
Sbjct: 38  CLVSKVVG-RCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENAT 96

Query: 202 ---ALPQWRKDKMAHLQFQSQSSSDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYD 372
              A  +   D       + Q S D    M    + C      G    +      R+Y+D
Sbjct: 97  GDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFP----RWYFD 152

Query: 373 NRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPDQ 477
                C  F + GC GN N++ +   C+  C   Q
Sbjct: 153 VERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQ 187
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,270,698
Number of Sequences: 369166
Number of extensions: 1966876
Number of successful extensions: 5130
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4567
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5090
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6534486000
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)