Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_J20
(731 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q02445|TFPI1_RAT Tissue factor pathway inhibitor precurs... 82 2e-15
sp|Q28864|TFPI1_MACMU Tissue factor pathway inhibitor precu... 81 3e-15
sp|Q03610|YN81_CAEEL Hypothetical protein ZC84.1 in chromos... 80 6e-15
sp|P10646|TFPI1_HUMAN Tissue factor pathway inhibitor precu... 77 5e-14
sp|P19761|TFPI1_RABIT Tissue factor pathway inhibitor precu... 74 4e-13
sp|O54819|TFPI1_MOUSE Tissue factor pathway inhibitor precu... 72 1e-12
sp|O35536|TFPI2_MOUSE Tissue factor pathway inhibitor 2 pre... 68 2e-11
sp|P48307|TFPI2_HUMAN Tissue factor pathway inhibitor 2 pre... 63 9e-10
sp|Q9WU03|SPIT2_MOUSE Kunitz-type protease inhibitor 2 prec... 60 8e-09
sp|O43291|SPIT2_HUMAN Kunitz-type protease inhibitor 2 prec... 60 8e-09
>sp|Q02445|TFPI1_RAT Tissue factor pathway inhibitor precursor (TFPI)
(Lipoprotein-associated coagulation inhibitor) (LACI)
(Extrinsic pathway inhibitor) (EPI)
Length = 302
Score = 81.6 bits (200), Expect = 2e-15
Identities = 48/148 (32%), Positives = 66/148 (44%), Gaps = 10/148 (6%)
Frame = +1
Query: 61 CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
C T YFY+ C F+Y GC G+ NNF T C TC + VN + +K
Sbjct: 133 CRGFMTRYFYNNQSKQCEQFKYGGCLGNSNNFETLEECRNTCEDPVNEV---QKGDYVTN 189
Query: 241 QFQSQSSSDKRKKMPTMADQCRLEVKYGGM----------YCNSTKYEIRYYYDNRNGRC 390
Q + + A + + Y G C ++ E R+YY+ G+C
Sbjct: 190 QITVTDRTTVNNVVIPQATKAPSQWDYDGPSWCLEPADSGLCKAS--EKRFYYNPAIGKC 247
Query: 391 RQFTFTGCDGNSNNFPTYHGCIKACMPD 474
RQF +TGC GN+NNF T C +AC D
Sbjct: 248 RQFNYTGCGGNNNNFTTKQDCNRACKKD 275
Score = 77.8 bits (190), Expect = 3e-14
Identities = 56/197 (28%), Positives = 85/197 (43%), Gaps = 26/197 (13%)
Frame = +1
Query: 61 CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
C +Y+++ + H C F Y GC+G+ N F T C KTC+ P ++K +
Sbjct: 62 CKAMIRSYYFNMNSHQCEEFIYGGCRGNKNRFDTLEECRKTCI------PGYKKTTI--- 112
Query: 241 QFQSQSSSDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDG 420
++ S ++K D C LE G C + RY+Y+N++ +C QF + GC G
Sbjct: 113 --KTTSGAEK-------PDFCFLEEDPG--ICRG--FMTRYFYNNQSKQCEQFKYGGCLG 159
Query: 421 NSNNFPTYHGCIKAC------------MPDQIDFMKTAPIKPCLV-------SEWSHWGP 543
NSNNF T C C + +QI + ++ S+W + GP
Sbjct: 160 NSNNFETLEECRNTCEDPVNEVQKGDYVTNQITVTDRTTVNNVVIPQATKAPSQWDYDGP 219
Query: 544 C-------SSLCGAGEK 573
S LC A EK
Sbjct: 220 SWCLEPADSGLCKASEK 236
>sp|Q28864|TFPI1_MACMU Tissue factor pathway inhibitor precursor (TFPI)
(Lipoprotein-associated coagulation inhibitor) (LACI)
(Extrinsic pathway inhibitor) (EPI)
Length = 304
Score = 80.9 bits (198), Expect = 3e-15
Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 5/140 (3%)
Frame = +1
Query: 61 CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
C T YFY+ C F+Y GC G++NNF T C+ TC + +N + L
Sbjct: 134 CRGYITRYFYNNQSKQCERFKYGGCLGNMNNFETLEECKNTCEDGLNGFQV--DNYGTQL 191
Query: 241 QFQSQSSSDKRKKMPTMAD-----QCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTF 405
+ S + + K+P+ + C G N E R+YY++ G+CR F +
Sbjct: 192 NAVNNSQTPQSTKVPSFFEFHGPSWCLAPADRGLCRAN----ENRFYYNSVIGKCRPFKY 247
Query: 406 TGCDGNSNNFPTYHGCIKAC 465
+GC GN NNF + C++AC
Sbjct: 248 SGCGGNENNFTSKRECLRAC 267
Score = 60.8 bits (146), Expect = 4e-09
Identities = 39/128 (30%), Positives = 56/128 (43%)
Frame = +1
Query: 82 YFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHLQFQSQSS 261
+F++ C F Y GC G+ N F + C+K C +D + H Q+
Sbjct: 70 FFFNIFTRQCEEFIYGGCGGNQNRFESMEECKKVC----------TRDNV-HRIIQTALQ 118
Query: 262 SDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDGNSNNFPT 441
+K D C LE G C Y RY+Y+N++ +C +F + GC GN NNF T
Sbjct: 119 QEK-------PDFCFLEEDPG--ICRG--YITRYFYNNQSKQCERFKYGGCLGNMNNFET 167
Query: 442 YHGCIKAC 465
C C
Sbjct: 168 LEECKNTC 175
Score = 37.7 bits (86), Expect = 0.032
Identities = 13/41 (31%), Positives = 22/41 (53%)
Frame = +1
Query: 358 RYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPDQI 480
R++++ +C +F + GC GN N F + C K C D +
Sbjct: 69 RFFFNIFTRQCEEFIYGGCGGNQNRFESMEECKKVCTRDNV 109
>sp|Q03610|YN81_CAEEL Hypothetical protein ZC84.1 in chromosome III
Length = 1416
Score = 80.1 bits (196), Expect = 6e-15
Identities = 54/175 (30%), Positives = 74/175 (42%), Gaps = 20/175 (11%)
Frame = +1
Query: 1 DTALCDP--VIICSEGLVIGSKCGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVC 174
D +C P IC++ L IG C Y+Y+A C FEY GC+G+ NNF + M C
Sbjct: 422 DQGVCCPRKQTICAQPLRIGD-CTENVKRYWYNARTRQCQMFEYTGCQGNDNNFDSIMDC 480
Query: 175 EKTCLEAVNALP-------QWRKDKMAHL-----------QFQSQSSSDKRKKMPTMADQ 300
+ C NA+P Q KD + ++ + PT A
Sbjct: 481 QNFC---KNAIPEPKCIQGQAYKDMFGNFVTCSNGMGCPANYECYFDGSQWGCCPTKAFT 537
Query: 301 CRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKAC 465
C L G+ C + +YYY+ + C F + GCDGNSNNF C C
Sbjct: 538 CSLNTD-SGIQCGAGS-TFKYYYNPQTQNCESFQYNGCDGNSNNFANRDACESYC 590
Score = 74.7 bits (182), Expect = 2e-13
Identities = 54/180 (30%), Positives = 72/180 (40%), Gaps = 20/180 (11%)
Frame = +1
Query: 31 CSEGLVIGSKCGNPTT-NYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNAL 207
CS G +CG +T Y+Y+ C SF+Y GC G+ NNF + CE C +V
Sbjct: 538 CSLNTDSGIQCGAGSTFKYYYNPQTQNCESFQYNGCDGNSNNFANRDACESYC--SVGGC 595
Query: 208 PQWRKDKMAHLQF------QSQSSSDKRKKMP-------------TMADQCRLEVKYGGM 330
P H Q S D + +P T A C L + G
Sbjct: 596 PNGGTPLRDHSGMVMVCGAQQTSCPDSHECIPVLVGNSLINRCCPTRAYMCGLPPQQGTQ 655
Query: 331 YCNSTKYEIRYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPDQIDFMKTAPIKP 510
C + Y RYY++ +C F F GCDGN+NNF C CM + A + P
Sbjct: 656 -CGAN-YVQRYYFNIVTSQCTSFQFGGCDGNANNFLNIQQCRNFCMSNACPAGNVAYVDP 713
Score = 66.2 bits (160), Expect = 8e-11
Identities = 41/142 (28%), Positives = 60/142 (42%), Gaps = 8/142 (5%)
Frame = +1
Query: 64 GNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTC--LEAVNALPQWRKDKMAH 237
G + ++YD C F Y G G+ NNF +K CE C L+ P ++
Sbjct: 347 GKESIRFYYDPGTGRCQDFVYKGAGGNYNNFLSKHECEMYCARLQCERGSPLRIGEEAQR 406
Query: 238 LQFQSQSSSDKRKK------MPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQF 399
Q +Q S K P C ++ G + T+ RY+Y+ R +C+ F
Sbjct: 407 CQNNAQCPSSHECKADQGVCCPRKQTICAQPLRIG----DCTENVKRYWYNARTRQCQMF 462
Query: 400 TFTGCDGNSNNFPTYHGCIKAC 465
+TGC GN NNF + C C
Sbjct: 463 EYTGCQGNDNNFDSIMDCQNFC 484
Score = 54.3 bits (129), Expect = 3e-07
Identities = 37/136 (27%), Positives = 50/136 (36%), Gaps = 28/136 (20%)
Frame = +1
Query: 142 SLNNFPTKMVCEKTCLEAVN-ALPQWRKDKMAHLQ---------------FQSQSSSDKR 273
S NNF T CE C + PQ+ + H + FQ + +
Sbjct: 252 SPNNFKTIQHCESYCRDTCQRGSPQYSTESAVHSERPITSCAASVSCANDFQCTAIGSQH 311
Query: 274 KKMPTMADQC------------RLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCD 417
PT C R + + G + K IR+YYD GRC+ F + G
Sbjct: 312 LCCPTPGSVCSAKGGRPYDIQPRTSIHHPGFMVYTGKESIRFYYDPGTGRCQDFVYKGAG 371
Query: 418 GNSNNFPTYHGCIKAC 465
GN NNF + H C C
Sbjct: 372 GNYNNFLSKHECEMYC 387
>sp|P10646|TFPI1_HUMAN Tissue factor pathway inhibitor precursor (TFPI)
(Lipoprotein-associated coagulation inhibitor) (LACI)
(Extrinsic pathway inhibitor) (EPI)
Length = 304
Score = 77.0 bits (188), Expect = 5e-14
Identities = 43/140 (30%), Positives = 66/140 (47%), Gaps = 5/140 (3%)
Frame = +1
Query: 61 CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
C T YFY+ C F+Y GC G++NNF T C+ C + N + L
Sbjct: 134 CRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQV--DNYGTQL 191
Query: 241 QFQSQSSSDKRKKMPTMAD-----QCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTF 405
+ S + + K+P++ + C G N E R+YY++ G+CR F +
Sbjct: 192 NAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRAN----ENRFYYNSVIGKCRPFKY 247
Query: 406 TGCDGNSNNFPTYHGCIKAC 465
+GC GN NNF + C++AC
Sbjct: 248 SGCGGNENNFTSKQECLRAC 267
Score = 57.8 bits (138), Expect = 3e-08
Identities = 36/128 (28%), Positives = 51/128 (39%)
Frame = +1
Query: 82 YFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHLQFQSQSS 261
+F++ C F Y GC+G+ N F + C+K C + +
Sbjct: 70 FFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTR------------------DNANR 111
Query: 262 SDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDGNSNNFPT 441
K D C LE G C Y RY+Y+N+ +C +F + GC GN NNF T
Sbjct: 112 IIKTTLQQEKPDFCFLEEDPG--ICRG--YITRYFYNNQTKQCERFKYGGCLGNMNNFET 167
Query: 442 YHGCIKAC 465
C C
Sbjct: 168 LEECKNIC 175
Score = 37.4 bits (85), Expect = 0.041
Identities = 13/39 (33%), Positives = 22/39 (56%)
Frame = +1
Query: 358 RYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPD 474
R++++ +C +F + GC+GN N F + C K C D
Sbjct: 69 RFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRD 107
>sp|P19761|TFPI1_RABIT Tissue factor pathway inhibitor precursor (TFPI)
(Lipoprotein-associated coagulation inhibitor) (LACI)
(Extrinsic pathway inhibitor) (EPI)
Length = 300
Score = 73.9 bits (180), Expect = 4e-13
Identities = 46/142 (32%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +1
Query: 61 CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
C T YFY+ C F+Y GC G+LNNF + C+ TC N ++ D
Sbjct: 130 CRGYITRYFYNNQSKQCERFKYGGCLGNLNNFESLEECKNTC---ENPTSDFQVDDH--- 183
Query: 241 QFQSQSSSDKRKKMPTMADQCRLEVKYGGMYCNSTK-------YEIRYYYDNRNGRCRQF 399
+ Q + ++ PT A R +G +C EIR++Y+ G+CR F
Sbjct: 184 RTQLNTVNNTLINQPTKAP--RRWAFHGPSWCLPPADRGLCQANEIRFFYNAIIGKCRPF 241
Query: 400 TFTGCDGNSNNFPTYHGCIKAC 465
++GC GN NNF + CI AC
Sbjct: 242 KYSGCGGNENNFTSKKACITAC 263
Score = 60.5 bits (145), Expect = 5e-09
Identities = 41/135 (30%), Positives = 58/135 (42%)
Frame = +1
Query: 82 YFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHLQFQSQSS 261
+F++ H C F Y GC+G+ N F + C++ C + L FQ
Sbjct: 66 FFFNILTHQCEEFIYGGCEGNENRFESLEECKEKCARDYPKMT-------TKLTFQ---- 114
Query: 262 SDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDGNSNNFPT 441
K P D C LE G C Y RY+Y+N++ +C +F + GC GN NNF +
Sbjct: 115 ----KGKP---DFCFLEEDPG--ICRG--YITRYFYNNQSKQCERFKYGGCLGNLNNFES 163
Query: 442 YHGCIKACMPDQIDF 486
C C DF
Sbjct: 164 LEECKNTCENPTSDF 178
Score = 36.6 bits (83), Expect = 0.071
Identities = 13/42 (30%), Positives = 23/42 (54%)
Frame = +1
Query: 349 YEIRYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPD 474
Y R++++ +C +F + GC+GN N F + C + C D
Sbjct: 62 YIKRFFFNILTHQCEEFIYGGCEGNENRFESLEECKEKCARD 103
>sp|O54819|TFPI1_MOUSE Tissue factor pathway inhibitor precursor (TFPI)
(Lipoprotein-associated coagulation inhibitor) (LACI)
(Extrinsic pathway inhibitor) (EPI)
Length = 306
Score = 72.4 bits (176), Expect = 1e-12
Identities = 43/150 (28%), Positives = 67/150 (44%), Gaps = 15/150 (10%)
Frame = +1
Query: 61 CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
C Y Y+ C F Y GC G+ NNF T C+K C V++ + +M+
Sbjct: 130 CRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKICENPVHSPSPVNEVQMSDY 189
Query: 241 QFQSQSSSDKRK----------KMPTMADQ-----CRLEVKYGGMYCNSTKYEIRYYYDN 375
+ +D+ K+P D C G C ++ E R+YY++
Sbjct: 190 VTDGNTVTDRSTVNNIVVPQSPKVPRRRDYRGRPWCLQPADSG--LCKAS--ERRFYYNS 245
Query: 376 RNGRCRQFTFTGCDGNSNNFPTYHGCIKAC 465
G+C +F +TGC GN+NNF T C+++C
Sbjct: 246 ATGKCHRFNYTGCGGNNNNFTTRRRCLRSC 275
Score = 70.1 bits (170), Expect = 6e-12
Identities = 44/135 (32%), Positives = 63/135 (46%)
Frame = +1
Query: 61 CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
C +YF++ H C F Y GC+G+ N F T C+KTC +P + K +
Sbjct: 59 CKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTC------IPGYEKTAV--- 109
Query: 241 QFQSQSSSDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTGCDG 420
++ S +++ D C LE G C Y RY Y+N+ +C +F + GC G
Sbjct: 110 --KAASGAER-------PDFCFLEEDPG--LCRG--YMKRYLYNNQTKQCERFVYGGCLG 156
Query: 421 NSNNFPTYHGCIKAC 465
N NNF T C K C
Sbjct: 157 NRNNFETLDECKKIC 171
Score = 41.6 bits (96), Expect = 0.002
Identities = 14/37 (37%), Positives = 22/37 (59%)
Frame = +1
Query: 361 YYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMP 471
Y+++ +C +F + GC+GN N F T C K C+P
Sbjct: 66 YFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTCIP 102
>sp|O35536|TFPI2_MOUSE Tissue factor pathway inhibitor 2 precursor (TFPI-2)
Length = 230
Score = 68.2 bits (165), Expect = 2e-11
Identities = 42/157 (26%), Positives = 66/157 (42%), Gaps = 28/157 (17%)
Frame = +1
Query: 82 YFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAH-------- 237
++YD + C F Y GC G+ NNF ++ +C++TC P R + +
Sbjct: 52 FYYDRDQQKCRRFNYGGCLGNANNFHSRDLCQQTCGSIEKVPPVCRSELKTYPCDKPNIR 111
Query: 238 --LQFQSQSSSDKRKKM-----------PTMADQCRLEVKYGGMYCNSTKYE-------I 357
+ + R + T C K+ +C+S K E
Sbjct: 112 FFFNLNTMTCEPLRPGLCSRTINVFSEEATCKGLCEPR-KHIPSFCSSPKDEGLCSANVT 170
Query: 358 RYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACM 468
R+Y+++RN C FT+TGC GN NNF C +AC+
Sbjct: 171 RFYFNSRNKTCETFTYTGCGGNENNFYYLDACHRACV 207
Score = 41.2 bits (95), Expect = 0.003
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +1
Query: 358 RYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKAC 465
++YYD +CR+F + GC GN+NNF + C + C
Sbjct: 51 KFYYDRDQQKCRRFNYGGCLGNANNFHSRDLCQQTC 86
Score = 39.7 bits (91), Expect = 0.008
Identities = 14/53 (26%), Positives = 26/53 (49%)
Frame = +1
Query: 61 CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWR 219
C T +++++ C +F Y GC G+ NNF C + C++ +W+
Sbjct: 165 CSANVTRFYFNSRNKTCETFTYTGCGGNENNFYYLDACHRACVKGWKKPKRWK 217
>sp|P48307|TFPI2_HUMAN Tissue factor pathway inhibitor 2 precursor (TFPI-2) (Placental
protein 5) (PP5)
Length = 235
Score = 62.8 bits (151), Expect = 9e-10
Identities = 46/166 (27%), Positives = 66/166 (39%), Gaps = 38/166 (22%)
Frame = +1
Query: 82 YFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKM-------AHL 240
Y+YD C F Y GC+G+ NNF T C+ C WR +K+ +
Sbjct: 52 YYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC---------WRIEKVPKVCRLQVSV 102
Query: 241 QFQSQSSSDK----------RKKMPTMADQCRLEVKYGG--------------MYCNSTK 348
Q + S++K K + R+E ++ +C S K
Sbjct: 103 DDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPK 162
Query: 349 YE-------IRYYYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKAC 465
E RYY++ R C FT+TGC GN NNF + C +AC
Sbjct: 163 DEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 54.7 bits (130), Expect = 3e-07
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
Frame = +1
Query: 238 LQFQSQSSSDKRKKMPT--MADQCRLEVKYGGMYCNSTKYEIRYYYDNRNGRCRQFTFTG 411
L F ++++ + PT A+ C L + YG C + +RYYYD CRQF + G
Sbjct: 13 LLFLTEAALGDAAQEPTGNNAEICLLPLDYGP--CRALL--LRYYYDRYTQSCRQFLYGG 68
Query: 412 CDGNSNNFPTYHGCIKAC 465
C+GN+NNF T+ C AC
Sbjct: 69 CEGNANNFYTWEACDDAC 86
Score = 47.8 bits (112), Expect = 3e-05
Identities = 22/73 (30%), Positives = 39/73 (53%)
Frame = +1
Query: 61 CGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALPQWRKDKMAHL 240
C T Y+++ C +F Y GC G+ NNF ++ C++ C +A+ +K KM L
Sbjct: 167 CSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALK-----KKKKMPKL 221
Query: 241 QFQSQSSSDKRKK 279
+F S+ ++K+
Sbjct: 222 RFASRIRKIRKKQ 234
>sp|Q9WU03|SPIT2_MOUSE Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth
factor activator inhibitor type 2) (HAI-2)
Length = 252
Score = 59.7 bits (143), Expect = 8e-09
Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 9/172 (5%)
Frame = +1
Query: 31 CSEGLVIGSKCGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVNALP 210
C V+G KC ++Y+ + C F Y GC+G+ NN+ +K + CL+ +
Sbjct: 38 CGVSKVVG-KCRASIPRWWYNITDGSCQPFVYGGCEGNGNNYQSK----EECLDKCAGVT 92
Query: 211 QWRKDKMAHLQFQSQSS--SDKRKKMPTMADQCRLEVKYGGMYCNSTKYE-------IRY 363
+ D MA + + SS S RK+ A+ E+ YC R+
Sbjct: 93 ENTTDDMARNRNGADSSVLSVPRKQS---AEDLSAEIFNYEEYCVPKAVTGPCRAAFPRW 149
Query: 364 YYDNRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPDQIDFMKTAPIKPCLV 519
YYD C F + GC GN N++ + C++ C Q+ T +K ++
Sbjct: 150 YYDTEKNSCISFIYGGCRGNKNSYLSQEACMQHCSGKQMHPFLTPGLKAVIL 201
>sp|O43291|SPIT2_HUMAN Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth
factor activator inhibitor type 2) (HAI-2) (Placental
bikunin)
Length = 252
Score = 59.7 bits (143), Expect = 8e-09
Identities = 39/155 (25%), Positives = 58/155 (37%), Gaps = 6/155 (3%)
Frame = +1
Query: 31 CSEGLVIGSKCGNPTTNYFYDASKHMCTSFEYLGCKGSLNNFPTKMVCEKTCLEAVN--- 201
C V+G +C ++Y+ + C F Y GC G+ NN+ TK C K C
Sbjct: 38 CLVSKVVG-RCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENAT 96
Query: 202 ---ALPQWRKDKMAHLQFQSQSSSDKRKKMPTMADQCRLEVKYGGMYCNSTKYEIRYYYD 372
A + D + Q S D M + C G + R+Y+D
Sbjct: 97 GDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFP----RWYFD 152
Query: 373 NRNGRCRQFTFTGCDGNSNNFPTYHGCIKACMPDQ 477
C F + GC GN N++ + C+ C Q
Sbjct: 153 VERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQ 187
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,270,698
Number of Sequences: 369166
Number of extensions: 1966876
Number of successful extensions: 5130
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4567
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5090
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6534486000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)