Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_014_I24 (159 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P30532|ACHA5_HUMAN Neuronal acetylcholine receptor prote... 72 4e-13 sp|P20420|ACHA5_RAT Neuronal acetylcholine receptor protein... 72 4e-13 sp|Q5IS51|ACHA5_PANTR Neuronal acetylcholine receptor prote... 72 4e-13 sp|P26152|ACHA5_CHICK Neuronal acetylcholine receptor prote... 71 9e-13 sp|P43679|ACHB3_CHICK Neuronal acetylcholine receptor prote... 70 1e-12 sp|Q8BMN3|ACHB3_MOUSE Neuronal acetylcholine receptor prote... 70 2e-12 sp|P12391|ACHB3_RAT Neuronal acetylcholine receptor protein... 70 2e-12 sp|Q5IS75|ACHB3_PANTR Neuronal acetylcholine receptor prote... 70 2e-12 sp|P05377|ACHAB_XENLA Acetylcholine receptor protein, alpha... 67 1e-11 sp|P14143|ACHA_NAJNA Acetylcholine receptor protein, alpha ... 66 3e-11
>sp|P30532|ACHA5_HUMAN Neuronal acetylcholine receptor protein, alpha-5 subunit precursor Length = 468 Score = 72.0 bits (175), Expect = 4e-13 Identities = 28/48 (58%), Positives = 39/48 (81%) Frame = +1 Query: 7 TYFPFDDQSCSMKFGSWTYDGTQLDIIKRQDDVDTSNYVHSGEWQLIT 150 T+FPFD Q+CSMKFGSWTYDG+Q+DII DVD ++ +GEW++++ Sbjct: 175 TFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVS 222
>sp|P20420|ACHA5_RAT Neuronal acetylcholine receptor protein, alpha-5 subunit precursor Length = 452 Score = 72.0 bits (175), Expect = 4e-13 Identities = 28/48 (58%), Positives = 40/48 (83%) Frame = +1 Query: 7 TYFPFDDQSCSMKFGSWTYDGTQLDIIKRQDDVDTSNYVHSGEWQLIT 150 T+FPFD Q+CSMKFGSWTYDG+Q+DII DVD +++ +GEW++++ Sbjct: 160 TFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDRTDFFDNGEWEIMS 207
>sp|Q5IS51|ACHA5_PANTR Neuronal acetylcholine receptor protein, alpha-5 subunit precursor Length = 468 Score = 72.0 bits (175), Expect = 4e-13 Identities = 28/48 (58%), Positives = 39/48 (81%) Frame = +1 Query: 7 TYFPFDDQSCSMKFGSWTYDGTQLDIIKRQDDVDTSNYVHSGEWQLIT 150 T+FPFD Q+CSMKFGSWTYDG+Q+DII DVD ++ +GEW++++ Sbjct: 175 TFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVS 222
>sp|P26152|ACHA5_CHICK Neuronal acetylcholine receptor protein, alpha-5 subunit precursor Length = 454 Score = 70.9 bits (172), Expect = 9e-13 Identities = 28/48 (58%), Positives = 39/48 (81%) Frame = +1 Query: 7 TYFPFDDQSCSMKFGSWTYDGTQLDIIKRQDDVDTSNYVHSGEWQLIT 150 T+FPFD Q+CSMKFGSWTYDG+Q+DII +VD ++ +GEW+++T Sbjct: 161 TFFPFDLQNCSMKFGSWTYDGSQVDIILEDYEVDKRDFFDNGEWEIVT 208
>sp|P43679|ACHB3_CHICK Neuronal acetylcholine receptor protein, beta-3 subunit precursor Length = 455 Score = 70.5 bits (171), Expect = 1e-12 Identities = 26/50 (52%), Positives = 40/50 (80%) Frame = +1 Query: 7 TYFPFDDQSCSMKFGSWTYDGTQLDIIKRQDDVDTSNYVHSGEWQLITVR 156 T+FPFD Q+CSMKFGSWTYDG+ +D+I ++VDT ++ +GEW+++ + Sbjct: 155 TFFPFDRQNCSMKFGSWTYDGSMVDLILVDENVDTKDFFDNGEWEILNAK 204
>sp|Q8BMN3|ACHB3_MOUSE Neuronal acetylcholine receptor protein, beta-3 subunit precursor Length = 464 Score = 70.1 bits (170), Expect = 2e-12 Identities = 26/50 (52%), Positives = 39/50 (78%) Frame = +1 Query: 7 TYFPFDDQSCSMKFGSWTYDGTQLDIIKRQDDVDTSNYVHSGEWQLITVR 156 T+FPFD Q+CSMKFGSWTYDGT +D+I ++VD ++ +GEW+++ + Sbjct: 164 TFFPFDKQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGEWEILNAK 213
>sp|P12391|ACHB3_RAT Neuronal acetylcholine receptor protein, beta-3 subunit precursor Length = 464 Score = 69.7 bits (169), Expect = 2e-12 Identities = 26/50 (52%), Positives = 39/50 (78%) Frame = +1 Query: 7 TYFPFDDQSCSMKFGSWTYDGTQLDIIKRQDDVDTSNYVHSGEWQLITVR 156 T+FPFD Q+CSMKFGSWTYDGT +D+I ++VD ++ +GEW+++ + Sbjct: 164 TFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGEWEILNAK 213
>sp|Q5IS75|ACHB3_PANTR Neuronal acetylcholine receptor protein, beta-3 subunit precursor sp|Q05901|ACHB3_HUMAN Neuronal acetylcholine receptor protein, beta-3 subunit precursor Length = 458 Score = 69.7 bits (169), Expect = 2e-12 Identities = 26/50 (52%), Positives = 39/50 (78%) Frame = +1 Query: 7 TYFPFDDQSCSMKFGSWTYDGTQLDIIKRQDDVDTSNYVHSGEWQLITVR 156 T+FPFD Q+CSMKFGSWTYDGT +D+I ++VD ++ +GEW+++ + Sbjct: 158 TFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGEWEILNAK 207
>sp|P05377|ACHAB_XENLA Acetylcholine receptor protein, alpha-1-B subunit precursor Length = 457 Score = 67.0 bits (162), Expect = 1e-11 Identities = 28/46 (60%), Positives = 35/46 (76%) Frame = +1 Query: 7 TYFPFDDQSCSMKFGSWTYDGTQLDIIKRQDDVDTSNYVHSGEWQL 144 TYFPFD Q+CSMKFG+WTYDG+ L I +D D SN++ SGEW + Sbjct: 153 TYFPFDQQNCSMKFGTWTYDGSLLVINPERDRPDLSNFMASGEWMM 198
>sp|P14143|ACHA_NAJNA Acetylcholine receptor protein, alpha subunit Length = 104 Score = 65.9 bits (159), Expect = 3e-11 Identities = 28/46 (60%), Positives = 33/46 (71%) Frame = +1 Query: 7 TYFPFDDQSCSMKFGSWTYDGTQLDIIKRQDDVDTSNYVHSGEWQL 144 TYFPFD+Q+CSMK G+WTYDGT + I D SNY+ SGEW L Sbjct: 15 TYFPFDEQNCSMKLGTWTYDGTVVAIYPEGPRPDLSNYMQSGEWTL 60
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,470,146 Number of Sequences: 369166 Number of extensions: 277151 Number of successful extensions: 782 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 760 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 761 length of database: 68,354,980 effective HSP length: 25 effective length of database: 63,736,605 effective search space used: 1720888335 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)