Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_H02
(905 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8CGF7|TCRG1_MOUSE Transcription elongation regulator 1 ... 204 3e-52
sp|O14776|TCRG1_HUMAN Transcription elongation regulator 1 ... 204 3e-52
sp|Q9R1C7|FNBP3_MOUSE Formin-binding protein 3 (Formin-bind... 43 0.001
sp|O75400|FNBP3_HUMAN Formin-binding protein 3 (Huntingtin ... 43 0.001
sp|Q09685|HGP1_SCHPO Hyphal growth protein 1 40 0.012
sp|Q9U7E0|ATRX_CAEEL Transcriptional regulator ATRX homolog... 37 0.099
sp|Q5F457|WBP4_CHICK WW domain-binding protein 4 (WBP-4) 35 0.38
sp|Q9UIF8|BAZ2B_HUMAN Bromodomain adjacent to zinc finger d... 32 1.9
sp|P33203|PRP40_YEAST Pre-mRNA processing protein PRP40 32 3.2
sp|P18418|CRTC_RAT Calreticulin precursor (CRP55) (Calregul... 32 3.2
>sp|Q8CGF7|TCRG1_MOUSE Transcription elongation regulator 1 (TATA box-binding
protein-associated factor 2S) (Transcription factor
CA150) (p144) (Formin-binding protein 28) (FBP 28)
Length = 1100
Score = 204 bits (519), Expect = 3e-52
Identities = 113/264 (42%), Positives = 150/264 (56%)
Frame = +1
Query: 91 KARDKSKPISSTPVSGTPWCIVWTGDGRVFYFNPAKRLSVWDRPDDLKDRTDVDKILQEP 270
KA K+KP+++TP+ GTPWC+VWTGD RVF++NP RLS+WDRPDDL R DVDKI+QEP
Sbjct: 518 KAAQKAKPVATTPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEP 577
Query: 271 PXXXXXXXXXXXXXXTNDSDEPPAKKQKINAGEEEKVASDTSEENEDEKEGSSASQNDAN 450
P + ++A +EE+ + E NEDE + + D N
Sbjct: 578 PHKKGLEDMKKLRHPAPTMLSIQKWQFSMSAIKEEQELME--EMNEDEPIKAKKRKRDDN 635
Query: 451 DISKDSIPLSXXXXXXXXXXXXXXRALLPMDVRVAQFREMLIEKQVSAFSTWEKELHKIV 630
KD I RA++P++ R+ QF++ML+E+ VSAFSTWEKELHKIV
Sbjct: 636 ---KD-IDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIV 691
Query: 631 FDPRYLLLVSKERKIAFENYVXXXXXXXXXXXXNQVRENKDLFKKLLKEASLNHXXXXXX 810
FDPRYLLL KERK F+ YV N++ + K+ FKK+++EA N
Sbjct: 692 FDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSE 751
Query: 811 XXXXXXXXERFKAIEKARDRETMF 882
RFKAIEK +DRE +F
Sbjct: 752 FAAKHAKDSRFKAIEKMKDREALF 775
Score = 44.3 bits (103), Expect = 5e-04
Identities = 26/110 (23%), Positives = 46/110 (41%)
Frame = +1
Query: 145 WCIVWTGDGRVFYFNPAKRLSVWDRPDDLKDRTDVDKILQEPPXXXXXXXXXXXXXXTND 324
W T DG+ +Y+N S W++P +LK++ +D+ ++EP
Sbjct: 437 WTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLDEKIKEP--------------IKEA 482
Query: 325 SDEPPAKKQKINAGEEEKVASDTSEENEDEKEGSSASQNDANDISKDSIP 474
S+EP + + +EE V E E+E + A ++ IP
Sbjct: 483 SEEPLPMETEEEDPKEEPVKEIKEEPKEEEMTEEEKAAQKAKPVATTPIP 532
Score = 33.1 bits (74), Expect = 1.1
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +1
Query: 145 WCIVWTGDGRVFYFNPAKRLSVWDRPDDLK 234
W T DG+V+Y+N R S W +PD +K
Sbjct: 137 WVENKTPDGKVYYYNARTRESAWTKPDGVK 166
>sp|O14776|TCRG1_HUMAN Transcription elongation regulator 1 (TATA box-binding
protein-associated factor 2S) (Transcription factor
CA150)
Length = 1098
Score = 204 bits (519), Expect = 3e-52
Identities = 113/264 (42%), Positives = 150/264 (56%)
Frame = +1
Query: 91 KARDKSKPISSTPVSGTPWCIVWTGDGRVFYFNPAKRLSVWDRPDDLKDRTDVDKILQEP 270
KA K+KP+++ P+ GTPWC+VWTGD RVF++NP RLS+WDRPDDL R DVDKI+QEP
Sbjct: 516 KAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEP 575
Query: 271 PXXXXXXXXXXXXXXTNDSDEPPAKKQKINAGEEEKVASDTSEENEDEKEGSSASQNDAN 450
P T + ++A +EE+ + E NEDE + + D N
Sbjct: 576 PHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELME--EINEDEPVKAKKRKRDDN 633
Query: 451 DISKDSIPLSXXXXXXXXXXXXXXRALLPMDVRVAQFREMLIEKQVSAFSTWEKELHKIV 630
KD I RA++P++ R+ QF++ML+E+ VSAFSTWEKELHKIV
Sbjct: 634 ---KD-IDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIV 689
Query: 631 FDPRYLLLVSKERKIAFENYVXXXXXXXXXXXXNQVRENKDLFKKLLKEASLNHXXXXXX 810
FDPRYLLL KERK F+ YV N++ + K+ FKK+++EA N
Sbjct: 690 FDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSE 749
Query: 811 XXXXXXXXERFKAIEKARDRETMF 882
RFKAIEK +DRE +F
Sbjct: 750 FAAKHAKDSRFKAIEKMKDREALF 773
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/110 (21%), Positives = 46/110 (41%)
Frame = +1
Query: 145 WCIVWTGDGRVFYFNPAKRLSVWDRPDDLKDRTDVDKILQEPPXXXXXXXXXXXXXXTND 324
W T DG+ +Y+N S W++P +LK++ +++ ++EP
Sbjct: 435 WTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEP--------------IKEP 480
Query: 325 SDEPPAKKQKINAGEEEKVASDTSEENEDEKEGSSASQNDANDISKDSIP 474
S+EP + + +EE + E E+E + A ++ IP
Sbjct: 481 SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIP 530
Score = 33.1 bits (74), Expect = 1.1
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +1
Query: 145 WCIVWTGDGRVFYFNPAKRLSVWDRPDDLK 234
W T DG+V+Y+N R S W +PD +K
Sbjct: 137 WVENKTPDGKVYYYNARTRESAWTKPDGVK 166
>sp|Q9R1C7|FNBP3_MOUSE Formin-binding protein 3 (Formin-binding protein 11) (FBP 11)
Length = 953
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +1
Query: 559 FREMLIEKQVSAFSTWEKELHKIVFDPRYLLLVS-KERKIAFENYVXXXXXXXXXXXXNQ 735
F+E+L EK+V + ++WE+ + I+ DPRY L E+K AF Y ++
Sbjct: 396 FKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSK 455
Query: 736 VRENKDLFKKLLK 774
+E K+ F++ L+
Sbjct: 456 YKEAKESFQRFLE 468
Score = 37.4 bits (85), Expect = 0.058
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 166 DGRVFYFNPAKRLSVWDRPDDLKDRTDVDKILQEPP 273
DGR +Y+N + S W++PDDLK T +++L + P
Sbjct: 153 DGRTYYYNTETKQSTWEKPDDLK--TPAEQLLSKCP 186
>sp|O75400|FNBP3_HUMAN Formin-binding protein 3 (Huntingtin yeast partner A)
(Huntingtin-interacting protein HYPA/FBP11) (Fas-ligand
associated factor 1) (NY-REN-6 antigen)
Length = 957
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +1
Query: 559 FREMLIEKQVSAFSTWEKELHKIVFDPRYLLLVS-KERKIAFENYVXXXXXXXXXXXXNQ 735
F+E+L EK+V + ++WE+ + I+ DPRY L E+K AF Y ++
Sbjct: 400 FKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSK 459
Query: 736 VRENKDLFKKLLK 774
+E K+ F++ L+
Sbjct: 460 YKEAKESFQRFLE 472
Score = 37.4 bits (85), Expect = 0.058
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 166 DGRVFYFNPAKRLSVWDRPDDLKDRTDVDKILQEPP 273
DGR +Y+N + S W++PDDLK T +++L + P
Sbjct: 153 DGRTYYYNTETKQSTWEKPDDLK--TPAEQLLSKCP 186
>sp|Q09685|HGP1_SCHPO Hyphal growth protein 1
Length = 411
Score = 39.7 bits (91), Expect = 0.012
Identities = 44/197 (22%), Positives = 70/197 (35%), Gaps = 15/197 (7%)
Frame = +1
Query: 145 WCIVWTGDGRVFYFNPAKRLSVWDRPDDL-KD--------RTDVDKILQEPPXXXXXXXX 297
W +V+T R F+ N S W+ P ++ KD R + K +
Sbjct: 95 WVVVFTKKNRYFFHNLKSHESYWEPPLEISKDLKILRLPIRKQISKDSSQSQNVDSGKTN 154
Query: 298 XXXXXXTNDSDEPPAKKQKINAGEEEKVAS-----DTSEENEDEKEGSSASQNDANDISK 462
+ + + EE V + S+E EDE++ SA + + +
Sbjct: 155 HEEIHESRHLQTEIEEPSGLEESSEESVLYSEEFYEKSDEEEDEEKSHSAEELEFGE-ED 213
Query: 463 DSIPLSXXXXXXXXXXXXXXRALLPMDVRVAQFREMLIEKQVSAFSTWEKELHKIVFDPR 642
L L D F E+L +K + A+ WE K++ D R
Sbjct: 214 IMYQLQQLDDETVSYDIQEQATNLSTDDARRVFTELLKDKNIGAYQPWELVYPKLLDDDR 273
Query: 643 YLLLVSKE-RKIAFENY 690
+ +L S E RK FE Y
Sbjct: 274 FYVLDSGERRKEVFEEY 290
>sp|Q9U7E0|ATRX_CAEEL Transcriptional regulator ATRX homolog (X-linked nuclear protein 1)
Length = 1359
Score = 36.6 bits (83), Expect = 0.099
Identities = 18/50 (36%), Positives = 29/50 (58%)
Frame = +1
Query: 319 NDSDEPPAKKQKINAGEEEKVASDTSEENEDEKEGSSASQNDANDISKDS 468
+D DE P+KK K G ++K S++ E+EDEKE + + + K+S
Sbjct: 186 SDEDEKPSKKSK--KGLKKKAKSESESESEDEKEVKKSKKKSKKVVKKES 233
Score = 30.4 bits (67), Expect = 7.1
Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +1
Query: 322 DSDEPPAKKQKINAGEEEK-VASDTSEENEDEKEGSSASQNDANDISK 462
DSDE +K K + + +K +S++SEE+E+E++ + +N + K
Sbjct: 131 DSDEEREQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKSVKK 178
>sp|Q5F457|WBP4_CHICK WW domain-binding protein 4 (WBP-4)
Length = 398
Score = 34.7 bits (78), Expect = 0.38
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 4/104 (3%)
Frame = +1
Query: 118 SSTPVSGTPWCIVWTGDGRVFYFNPAKRLSVWDRPDDL----KDRTDVDKILQEPPXXXX 285
S T +G+ W + DG +Y+N +S W++PD D + K +E
Sbjct: 172 SKTSHTGSVWVEGVSEDGHTYYYNTQTGVSTWEKPDGFVSSSNDNSQRGKHSEE------ 225
Query: 286 XXXXXXXXXXTNDSDEPPAKKQKINAGEEEKVASDTSEENEDEK 417
+DS++ ++ + + G K + EE+E EK
Sbjct: 226 ----ADSRASESDSEQEDSESEGQSPGTNLKRKGENDEESEKEK 265
>sp|Q9UIF8|BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain 2B (hWALp4)
Length = 1972
Score = 32.3 bits (72), Expect = 1.9
Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Frame = +1
Query: 322 DSDEPPAK-KQKINAGEEEKVASDTSEENEDEKEGSSASQNDANDIS 459
DSD P +K + N EEE + E++ED++ S S++D+N S
Sbjct: 399 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSES 445
>sp|P33203|PRP40_YEAST Pre-mRNA processing protein PRP40
Length = 583
Score = 31.6 bits (70), Expect = 3.2
Identities = 43/216 (19%), Positives = 80/216 (37%), Gaps = 3/216 (1%)
Frame = +1
Query: 145 WCIVWTGDGRVFYFNPAKRLSVWDRPDDLKDRTDVDKILQEPPXXXXXXXXXXXXXXTND 324
W T DG+V+Y+NP R + W P K V+ I ++ T
Sbjct: 45 WKAAKTADGKVYYYNPTTRETSWTIPAFEK---KVEPIAEQ-------------KHDTVS 88
Query: 325 SDEPPAKKQKINAGEEEKVASDTSEENEDEKEGSSASQNDANDISKDSIPLSXXXXXXXX 504
+ + + AGE+++ +EE E + +S N +++
Sbjct: 89 HAQVNGNRIALTAGEKQEPGRTINEE-ESQYANNSKLLNVRRRTKEEA------------ 135
Query: 505 XXXXXXRALLPMDVRVAQFREMLIEKQVSAFSTWEKELHKI-VFDPRYLLLVSKE--RKI 675
+F ML E QV + ++ + + ++ DPRY ++ +K
Sbjct: 136 ---------------EKEFITMLKENQVDSTWSFSRIISELGTRDPRYWMVDDDPLWKKE 180
Query: 676 AFENYVXXXXXXXXXXXXNQVRENKDLFKKLLKEAS 783
FE Y+ N+ + K+ F+K+L+ S
Sbjct: 181 MFEKYLSNRSADQLLKEHNETSKFKEAFQKMLQNNS 216
>sp|P18418|CRTC_RAT Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (CALBP)
(Calcium-binding protein 3) (CABP3)
Length = 416
Score = 31.6 bits (70), Expect = 3.2
Identities = 15/48 (31%), Positives = 25/48 (52%)
Frame = +1
Query: 328 DEPPAKKQKINAGEEEKVASDTSEENEDEKEGSSASQNDANDISKDSI 471
+E KK+K E+K D +E+EDE++ + DA +KD +
Sbjct: 369 EEEEDKKRKEEEEAEDKEDEDDRDEDEDEEDEKEEDEEDATGQAKDEL 416
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.315 0.132 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,916,009
Number of Sequences: 369166
Number of extensions: 1480120
Number of successful extensions: 6517
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5218
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6159
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9174518830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)