Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_G20
(769 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9H6R6|ZDHC6_HUMAN Probable palmitoyltransferase ZDHHC6 ... 262 7e-70
sp|Q9CPV7|ZDHC6_MOUSE Probable palmitoyltransferase ZDHHC6 ... 254 2e-67
sp|Q4PE27|PFA4_USTMA Palmitoyltransferase PFA4 (Protein fat... 122 1e-27
sp|Q9ESG8|ZDH16_MOUSE Probable palmitoyltransferase ZDHHC16... 108 2e-23
sp|Q5KLN1|PFA4_CRYNE Palmitoyltransferase PFA4 (Protein fat... 108 2e-23
sp|Q58CU4|ZDH16_BOVIN Probable palmitoyltransferase ZDHHC16... 103 4e-22
sp|Q969W1|ZDH16_HUMAN Probable palmitoyltransferase ZDHHC16... 102 1e-21
sp|Q4R7E2|ZDH16_MACFA Probable palmitoyltransferase ZDHHC16... 102 1e-21
sp|Q5BD15|PFA4_EMENI Palmitoyltransferase PFA4 (Protein fat... 97 5e-20
sp|Q6BLY8|PFA4_DEBHA Palmitoyltransferase PFA4 (Protein fat... 93 7e-19
>sp|Q9H6R6|ZDHC6_HUMAN Probable palmitoyltransferase ZDHHC6 (Zinc finger DHHC
domain-containing protein 6) (DHHC-6) (Zinc finger
protein 376) (Transmembrane protein H4)
sp|Q5REH2|ZDHC6_PONPY Probable palmitoyltransferase ZDHHC6 (Zinc finger DHHC
domain-containing protein 6) (DHHC-6)
Length = 413
Score = 262 bits (670), Expect = 7e-70
Identities = 123/265 (46%), Positives = 168/265 (63%), Gaps = 13/265 (4%)
Frame = +3
Query: 12 IHFSIYVYEFYLVVNNYLNASFIGPGFVNLGWEPKLEDDKQFLQYCELCEGYKPPRSHHC 191
++F + + +++ NY NA F+GPGFV LGW+P++ D +LQYC++C+ YK PRSHHC
Sbjct: 56 VNFIMLINWTVMILYNYFNAMFVGPGFVPLGWKPEISQDTMYLQYCKVCQAYKAPRSHHC 115
Query: 192 RKCDRCVMKMDHHCPWINTCCGHLNHGYFVYFLFFAPIGCIHSTYILGLTLYYAIYVDYF 371
RKC+RCVMKMDHHCPWIN CCG+ NH F FL AP+GCIH+ +I +T+Y +Y
Sbjct: 116 RKCNRCVMKMDHHCPWINNCCGYQNHASFTLFLLLAPLGCIHAAFIFVMTMYTQLYHRLS 175
Query: 372 FNF------------DDQYIVILSLMEFLCSFFXXXXXXXXXXXXXSLWVIQMRSIMKNE 515
F + D IV L F + F L+ IQM+ I++N+
Sbjct: 176 FGWNTVKIDMSAARRDPLPIVPFGLAAFATTLFALGLALGTTIAVGMLFFIQMKIILRNK 235
Query: 516 TGVESWIKEKSQLRIQENNNSNERFVYPYDLG-RIRNMKEILTWSGRCRGDGITWTVKDG 692
T +ESWI+EK++ RIQ +E FV+PYD+G R RN K++ TWSG GDG+ W V++G
Sbjct: 236 TSIESWIEEKAKDRIQ-YYQLDEVFVFPYDMGSRWRNFKQVFTWSGVPEGDGLEWPVREG 294
Query: 693 CGQYDLTIEQIKQKRDKVLHSQNYE 767
C QY LTIEQ+KQK DK + S Y+
Sbjct: 295 CHQYSLTIEQLKQKADKRVRSVRYK 319
>sp|Q9CPV7|ZDHC6_MOUSE Probable palmitoyltransferase ZDHHC6 (Zinc finger DHHC
domain-containing protein 6) (DHHC-6) (H4 homolog)
Length = 413
Score = 254 bits (649), Expect = 2e-67
Identities = 117/265 (44%), Positives = 164/265 (61%), Gaps = 13/265 (4%)
Frame = +3
Query: 12 IHFSIYVYEFYLVVNNYLNASFIGPGFVNLGWEPKLEDDKQFLQYCELCEGYKPPRSHHC 191
++F + + +++ NY NA F GPGFV GW+P+ D +LQYC++C+ YK PRSHHC
Sbjct: 56 VNFIMLINWTVMILYNYFNAMFAGPGFVPRGWKPEKSQDSMYLQYCKVCQAYKAPRSHHC 115
Query: 192 RKCDRCVMKMDHHCPWINTCCGHLNHGYFVYFLFFAPIGCIHSTYILGLTLYYAIYVDYF 371
RKC+RCVMKMDHHCPWIN CCGH NH F FL AP+GC H+ +I +T+Y +Y
Sbjct: 116 RKCNRCVMKMDHHCPWINNCCGHQNHASFTLFLLLAPLGCTHAAFIFVMTMYTQLYNRLS 175
Query: 372 FNF------------DDQYIVILSLMEFLCSFFXXXXXXXXXXXXXSLWVIQMRSIMKNE 515
F + D IV L F + F L+ IQ++ I++N+
Sbjct: 176 FGWNTVKIDMSAARRDPPPIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQIKIILRNK 235
Query: 516 TGVESWIKEKSQLRIQENNNSNERFVYPYDLG-RIRNMKEILTWSGRCRGDGITWTVKDG 692
T +ESWI+EK++ RIQ +E F++PYD+G + +N K++ TWSG GDG+ W +++G
Sbjct: 236 TSIESWIEEKAKDRIQ-YYQLDEVFIFPYDMGSKWKNFKQVFTWSGVPEGDGLEWPIREG 294
Query: 693 CGQYDLTIEQIKQKRDKVLHSQNYE 767
C QY LTIEQ+KQK DK + S Y+
Sbjct: 295 CDQYSLTIEQLKQKADKRVRSVRYK 319
>sp|Q4PE27|PFA4_USTMA Palmitoyltransferase PFA4 (Protein fatty acyltransferase 4)
Length = 604
Score = 122 bits (305), Expect = 1e-27
Identities = 65/210 (30%), Positives = 106/210 (50%), Gaps = 12/210 (5%)
Frame = +3
Query: 108 EPKLEDDKQFLQ--YCELCEGYKPPRSHHCRKCDRCVMKMDHHCPWINTCCGHLNHGYFV 281
EP LE + + YC+ C +KPPRSHHC+ C RCV++MDHHCPW+ C GH NH +F+
Sbjct: 168 EPSLELKQAIYRPRYCKTCSAFKPPRSHHCKTCQRCVLRMDHHCPWLANCVGHFNHAHFI 227
Query: 282 YFLFFAPIGCIHSTYILGLTLYYAIYVDYFFNFDDQYIVILSLMEFLCSFFXXXXXXXXX 461
FLF+ + C++ ++ + +D F ++ + +L +
Sbjct: 228 RFLFYVDVTCLYHLIMISCRV-----LDSFNSYTYWREPCARELVWLVVNYALCIPVILL 282
Query: 462 XXXXSLWVIQMRSIMKNETGVESWIKEKSQLRIQENNNSNERFVYPYDLGRIRNMKEI-- 635
SL+ ++ N+T +ESW K+++ I+ + YPYDLG RN++++
Sbjct: 283 VGIFSLYHFYCLAV--NQTTIESWEKDRTATMIRRGR--VRKVKYPYDLGLWRNVRQVLG 338
Query: 636 ---LTW-----SGRCRGDGITWTVKDGCGQ 701
L W R GDG+ + V +G G+
Sbjct: 339 ASPLVWCLPGAGARMAGDGLKYPVANGLGK 368
>sp|Q9ESG8|ZDH16_MOUSE Probable palmitoyltransferase ZDHHC16 (Zinc finger DHHC
domain-containing protein 16) (DHHC-16) (Abl-philin 2)
Length = 361
Score = 108 bits (269), Expect = 2e-23
Identities = 71/217 (32%), Positives = 102/217 (47%), Gaps = 9/217 (4%)
Frame = +3
Query: 15 HFSIYVYEFYLVVNNYLNASFIGPGFVNLGWEPKLEDDKQFLQYCELCEGYKPPRSHHCR 194
HF + L+V +Y A PG+ P+ +D + C+ C KP R+HHC
Sbjct: 118 HFFYSHWNLILIVFHYYQAITTPPGY-----PPQGRNDIATVSICKKCIYPKPARTHHCS 172
Query: 195 KCDRCVMKMDHHCPWINTCCGHLNHGYFVYFLFFAPIGCIHSTY---ILGLTLYYAIYVD 365
C+RCV+KMDHHCPW+N C GH NH YF F FF +GC++ +Y L Y AI
Sbjct: 173 ICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIETY 232
Query: 366 Y-----FFNFDDQYI-VILSLMEFLCSFFXXXXXXXXXXXXXSLWVIQMRSIMKNETGVE 527
+ F+F ++ L + FLCS ++W + I + ET +E
Sbjct: 233 HQTPPPTFSFRERITHKSLVYLWFLCS------SVALALGALTMWHAVL--ISRGETSIE 284
Query: 528 SWIKEKSQLRIQENNNSNERFVYPYDLGRIRNMKEIL 638
I +K + R+Q F PY+ G + N K L
Sbjct: 285 RHINKKERRRLQAKGRV---FRNPYNYGCLDNWKVFL 318
>sp|Q5KLN1|PFA4_CRYNE Palmitoyltransferase PFA4 (Protein fatty acyltransferase 4)
Length = 456
Score = 108 bits (269), Expect = 2e-23
Identities = 65/236 (27%), Positives = 109/236 (46%), Gaps = 15/236 (6%)
Frame = +3
Query: 42 YLVVNNYLNASFIGPGFVNLGWEPKL--------EDDKQFLQYCELCEGYKPPRSHHCRK 197
+++ NY PG V GW P + + +YC+ CE YKPPR+HHCR+
Sbjct: 54 FMIFWNYRLCVITSPGSVPEGWRPNIGAMDGMEVKKGTHTPRYCKNCEHYKPPRAHHCRQ 113
Query: 198 CDRCVMKMDHHCPWINTCCGHLNHGYFVYFLFFAPIGCIHSTYILGLTLYYAIYVDYFFN 377
C C + +HCPWI C G N G+F+ FL + IG +T+ L + + +Y+ +++
Sbjct: 114 CKTCWV---NHCPWIGNCVGFYNQGHFIRFLLWVDIG---TTFHLIIMVRRVLYIAEYYH 167
Query: 378 FDDQYIVILSLMEFLCSFFXXXXXXXXXXXXXSLWVIQMRSIMKNETGVESWIKEKSQLR 557
+ +L FL F S++ + + N T +E W K+K
Sbjct: 168 QEPTLADVL----FLVFNFATCVPVWLCVGMFSIYHVYL--ACGNSTTIEGWEKDKVATL 221
Query: 558 IQENNNSNERFVYPYDLGRIRNMKEIL-------TWSGRCRGDGITWTVKDGCGQY 704
I+ + YPY++G +N+K +L W + +GDG+++ V G +
Sbjct: 222 IRRGKIKEVK--YPYNIGIYKNIKSVLGPNPFLWLWPQKMQGDGLSFPVNPSAGDH 275
>sp|Q58CU4|ZDH16_BOVIN Probable palmitoyltransferase ZDHHC16 (Zinc finger DHHC
domain-containing protein 16) (DHHC-16)
Length = 377
Score = 103 bits (258), Expect = 4e-22
Identities = 44/104 (42%), Positives = 60/104 (57%)
Frame = +3
Query: 15 HFSIYVYEFYLVVNNYLNASFIGPGFVNLGWEPKLEDDKQFLQYCELCEGYKPPRSHHCR 194
HF + L+V +Y A PG+ P+ +D + C+ C KP R+HHC
Sbjct: 118 HFFYSHWNLILIVFHYYQAITTPPGY-----PPQGRNDMTTVSICKKCINPKPARTHHCS 172
Query: 195 KCDRCVMKMDHHCPWINTCCGHLNHGYFVYFLFFAPIGCIHSTY 326
C+RCV+KMDHHCPW+N C GH NH YF F FF +GC++ +Y
Sbjct: 173 ICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSY 216
>sp|Q969W1|ZDH16_HUMAN Probable palmitoyltransferase ZDHHC16 (Zinc finger DHHC
domain-containing protein 16) (DHHC-16)
Length = 377
Score = 102 bits (253), Expect = 1e-21
Identities = 44/104 (42%), Positives = 60/104 (57%)
Frame = +3
Query: 15 HFSIYVYEFYLVVNNYLNASFIGPGFVNLGWEPKLEDDKQFLQYCELCEGYKPPRSHHCR 194
HF + L+V +Y A PG+ P+ +D + C+ C KP R+HHC
Sbjct: 118 HFFYSHWNLILIVFHYYQAITTPPGY-----PPQGRNDIATVSICKKCIYPKPARTHHCS 172
Query: 195 KCDRCVMKMDHHCPWINTCCGHLNHGYFVYFLFFAPIGCIHSTY 326
C+RCV+KMDHHCPW+N C GH NH YF F FF +GC++ +Y
Sbjct: 173 ICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSY 216
>sp|Q4R7E2|ZDH16_MACFA Probable palmitoyltransferase ZDHHC16 (Zinc finger DHHC
domain-containing protein 16) (DHHC-16)
Length = 377
Score = 102 bits (253), Expect = 1e-21
Identities = 44/104 (42%), Positives = 60/104 (57%)
Frame = +3
Query: 15 HFSIYVYEFYLVVNNYLNASFIGPGFVNLGWEPKLEDDKQFLQYCELCEGYKPPRSHHCR 194
HF + L+V +Y A PG+ P+ +D + C+ C KP R+HHC
Sbjct: 118 HFFYSHWNLILIVFHYYQAITTPPGY-----PPQGRNDIATVSICKKCIYPKPARTHHCS 172
Query: 195 KCDRCVMKMDHHCPWINTCCGHLNHGYFVYFLFFAPIGCIHSTY 326
C+RCV+KMDHHCPW+N C GH NH YF F FF +GC++ +Y
Sbjct: 173 ICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSY 216
>sp|Q5BD15|PFA4_EMENI Palmitoyltransferase PFA4 (Protein fatty acyltransferase 4)
Length = 435
Score = 97.1 bits (240), Expect = 5e-20
Identities = 41/89 (46%), Positives = 54/89 (60%), Gaps = 6/89 (6%)
Frame = +3
Query: 60 YLNASFIGPGFVNLGWEP----KLEDDKQF--LQYCELCEGYKPPRSHHCRKCDRCVMKM 221
Y A + PG V GW P +L+ D+ ++C CE YKPPR+HHC+ C+RCV KM
Sbjct: 58 YYRACTVDPGHVPKGWMPSDRERLKADRASGRQRWCRRCEAYKPPRAHHCKTCERCVPKM 117
Query: 222 DHHCPWINTCCGHLNHGYFVYFLFFAPIG 308
DHHCPW + C H +F FLF+A +G
Sbjct: 118 DHHCPWTSNCVSHFTFPHFARFLFYAVVG 146
>sp|Q6BLY8|PFA4_DEBHA Palmitoyltransferase PFA4 (Protein fatty acyltransferase 4)
Length = 402
Score = 93.2 bits (230), Expect = 7e-19
Identities = 41/104 (39%), Positives = 63/104 (60%), Gaps = 2/104 (1%)
Frame = +3
Query: 30 VYEFYLVVN--NYLNASFIGPGFVNLGWEPKLEDDKQFLQYCELCEGYKPPRSHHCRKCD 203
+YE Y+ + +Y A + PG + PK ++ ++C+ C+ YKP RSHHC+ C+
Sbjct: 42 LYEVYVCIVWLSYYLAIVVDPGSPPKNFTPKA---GEWRRWCKKCQNYKPERSHHCKTCN 98
Query: 204 RCVMKMDHHCPWINTCCGHLNHGYFVYFLFFAPIGCIHSTYILG 335
+CV+KMDHHCPW C GH N +F+ F+FF +G + + LG
Sbjct: 99 KCVLKMDHHCPWTYNCVGHNNLPHFLRFVFFLIVGMTYVLFQLG 142
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,501,690
Number of Sequences: 369166
Number of extensions: 2058168
Number of successful extensions: 7158
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6476
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7027
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7115329200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)