Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_G04
(614 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine ... 251 8e-67
sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine ... 250 2e-66
sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine ... 245 6e-65
sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine ca... 242 6e-64
sp|Q27257|DIF1_CAEEL Protein dif-1 223 4e-58
sp|Q9VQG4|COLT_DROME Congested-like trachea protein 207 2e-53
sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine ... 126 4e-29
sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1... 120 4e-27
sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1... 118 1e-26
sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier 113 4e-25
>sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 251 bits (642), Expect = 8e-67
Identities = 123/184 (66%), Positives = 144/184 (78%)
Frame = +1
Query: 4 IFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKG 183
+FAAGMLSGVFTT IMTPGERIKCLLQ+Q +S E KY G D +KLY+E GIR IYKG
Sbjct: 113 LFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGES-KYTGTLDCAKKLYQEFGIRGIYKG 171
Query: 184 TAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPD 363
T TL+RD+PA+G YFM+YEWLK I TPEG S LS R L AGGIAG+ NW V IPPD
Sbjct: 172 TVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPD 231
Query: 364 TLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSL 543
LKSR QTAP GKYP+G R V RE++ +EG+ LY+G + V+IRAFPANAACFLG+EV++
Sbjct: 232 VLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAM 291
Query: 544 KLLN 555
K LN
Sbjct: 292 KFLN 295
Score = 66.6 bits (161), Expect = 5e-11
Identities = 40/95 (42%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 289 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 453
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 454 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 558
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
Score = 63.9 bits (154), Expect = 3e-10
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 5/179 (2%)
Frame = +1
Query: 13 AGMLSGVFTTAIMTPGERIKCLLQVQGASK--EPPKYKGPGDVIRKLYKEGGIRSIYKGT 186
AG GV + P + +K LQ Q S +PP Y G D RK GI +Y+G
Sbjct: 16 AGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGM 75
Query: 187 AATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDT 366
AA ++ P F + K++ D LS + AG ++G+ + P +
Sbjct: 76 AAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDV--LSYPQLFAAGMLSGVFTTGIMTPGER 133
Query: 367 LKSRLQ---TAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 534
+K LQ ++ E KY G +++ GI G+Y+G L+R PA+ F+ YE
Sbjct: 134 IKCLLQIQASSGESKYT-GTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYE 191
>sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 250 bits (639), Expect = 2e-66
Identities = 121/184 (65%), Positives = 144/184 (78%)
Frame = +1
Query: 4 IFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKG 183
+FAAGMLSG+FTT IMTPGERIKCLLQ+Q +S E KY G D +KLY+E GIR IYKG
Sbjct: 113 LFAAGMLSGIFTTGIMTPGERIKCLLQIQASSGET-KYTGTLDCAKKLYQEFGIRGIYKG 171
Query: 184 TAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPD 363
T TL+RD+PA+G YFM+YEW+K I TPEG S LS R L AGGIAG+ NW V IPPD
Sbjct: 172 TVVTLMRDVPASGMYFMTYEWVKNIFTPEGKRVSELSVPRVLVAGGIAGIFNWAVAIPPD 231
Query: 364 TLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSL 543
LKSR QTAP GKYP+G R V RE++ +EG+ LY+G + V+IRAFPANAACFLG+EV++
Sbjct: 232 VLKSRFQTAPPGKYPNGFRDVLRELIPDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAM 291
Query: 544 KLLN 555
K LN
Sbjct: 292 KFLN 295
Score = 65.9 bits (159), Expect = 8e-11
Identities = 53/179 (29%), Positives = 81/179 (45%), Gaps = 5/179 (2%)
Frame = +1
Query: 13 AGMLSGVFTTAIMTPGERIKCLLQVQGASK--EPPKYKGPGDVIRKLYKEGGIRSIYKGT 186
AG GV + P + +K LQ Q S +PP Y G D RK GIR +Y+G
Sbjct: 16 AGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGIRGLYRGM 75
Query: 187 AATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDT 366
AA ++ P F + K++ D LS + AG ++G+ + P +
Sbjct: 76 AAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDV--LSYPQLFAAGMLSGIFTTGIMTPGER 133
Query: 367 LKSRLQ---TAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 534
+K LQ ++ E KY G +++ GI G+Y+G L+R PA+ F+ YE
Sbjct: 134 IKCLLQIQASSGETKYT-GTLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASGMYFMTYE 191
Score = 65.5 bits (158), Expect = 1e-10
Identities = 40/95 (42%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 289 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 453
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 454 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 558
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 IRGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
>sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC) (mCAC)
Length = 301
Score = 245 bits (626), Expect = 6e-65
Identities = 118/184 (64%), Positives = 140/184 (76%)
Frame = +1
Query: 4 IFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKG 183
+F AGMLSGVFTT IMTPGERIKCLLQ+Q +S E KY G D +KLY+E GIR YKG
Sbjct: 113 LFTAGMLSGVFTTGIMTPGERIKCLLQIQASSGEN-KYSGTLDCAKKLYQEFGIRGFYKG 171
Query: 184 TAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPD 363
T TL+RD+PA+G YFM+YEWLK + TPEG S LS R L AGG AG+ NW V IPPD
Sbjct: 172 TVLTLMRDVPASGMYFMTYEWLKNLFTPEGKSVSDLSVPRILVAGGFAGIFNWAVAIPPD 231
Query: 364 TLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSL 543
LKSR QTAP GKYP+G R V RE++ EG+ LY+G + V+IRAFPANAACFLG+E+++
Sbjct: 232 VLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIAM 291
Query: 544 KLLN 555
K LN
Sbjct: 292 KFLN 295
Score = 69.7 bits (169), Expect = 6e-12
Identities = 41/95 (43%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 289 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYP--HGLRSVFREMMANEG 453
+SP + L AGG GMC V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREG 67
Query: 454 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 558
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
Score = 64.3 bits (155), Expect = 2e-10
Identities = 50/179 (27%), Positives = 80/179 (44%), Gaps = 5/179 (2%)
Frame = +1
Query: 13 AGMLSGVFTTAIMTPGERIKCLLQVQ--GASKEPPKYKGPGDVIRKLYKEGGIRSIYKGT 186
AG G+ + P + +K LQ Q S +PP Y G D RK GI +Y+G
Sbjct: 16 AGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREGITGLYRGM 75
Query: 187 AATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDT 366
AA ++ P F + K++ + + LS + AG ++G+ + P +
Sbjct: 76 AAPIIGVTPMFAVCFFGFGLGKKL--QQKSPEDELSYPQLFTAGMLSGVFTTGIMTPGER 133
Query: 367 LKSRLQ---TAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 534
+K LQ ++ E KY G +++ GI G Y+G L+R PA+ F+ YE
Sbjct: 134 IKCLLQIQASSGENKY-SGTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYE 191
>sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 242 bits (617), Expect = 6e-64
Identities = 116/184 (63%), Positives = 139/184 (75%)
Frame = +1
Query: 4 IFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKG 183
+F AGMLSGVFTT IMTPGERIKCLLQ+Q AS KY G D +KLY+E GIR YKG
Sbjct: 113 LFTAGMLSGVFTTGIMTPGERIKCLLQIQ-ASSGKNKYSGTLDCAKKLYQEFGIRGFYKG 171
Query: 184 TAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPD 363
TA TL+RD+PA+G YFM+YEWLK + TP+G LS R L AGG G+ NW+V IPPD
Sbjct: 172 TALTLMRDVPASGMYFMTYEWLKNLFTPQGKSVHDLSVPRVLVAGGFRGIFNWVVAIPPD 231
Query: 364 TLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSL 543
LKSR QTAP GKYP+G R V RE++ EG+ LY+G + V+IRAFPANAACFLG+E+ +
Sbjct: 232 VLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIPM 291
Query: 544 KLLN 555
K+LN
Sbjct: 292 KILN 295
Score = 65.5 bits (158), Expect = 1e-10
Identities = 39/95 (41%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 289 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 453
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREG 67
Query: 454 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 558
I GLYRG++ +I P A CF G+ + +L K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQK 102
Score = 62.8 bits (151), Expect = 7e-10
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +1
Query: 13 AGMLSGVFTTAIMTPGERIKCLLQVQGASK--EPPKYKGPGDVIRKLYKEGGIRSIYKGT 186
AG GV + P + +K LQ Q S +PP Y G D RK GI +Y+G
Sbjct: 16 AGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREGITGLYRGM 75
Query: 187 AATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDT 366
AA ++ P F + K + + + L+ + AG ++G+ + P +
Sbjct: 76 AAPIIGVTPMFAVCFFGFGLGKRL--QQKSPEDELTYPQLFTAGMLSGVFTTGIMTPGER 133
Query: 367 LKSRLQ-TAPEGKYPH-GLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 534
+K LQ A GK + G +++ GI G Y+G + L+R PA+ F+ YE
Sbjct: 134 IKCLLQIQASSGKNKYSGTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYE 191
>sp|Q27257|DIF1_CAEEL Protein dif-1
Length = 312
Score = 223 bits (567), Expect = 4e-58
Identities = 111/179 (62%), Positives = 136/179 (75%), Gaps = 2/179 (1%)
Frame = +1
Query: 13 AGMLSGVFTTAIMTPGERIKCLLQVQ--GASKEPPKYKGPGDVIRKLYKEGGIRSIYKGT 186
AG L+GVFTT +M PGERIKCLLQVQ G++ Y GP DV++KLYK+GGI SIY+GT
Sbjct: 110 AGALAGVFTTIVMVPGERIKCLLQVQQAGSAGSGVHYDGPLDVVKKLYKQGGISSIYRGT 169
Query: 187 AATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDT 366
ATLLRDIPA+ Y YE+LK+ + EG ++ LSPG TL AGG+AG+ NW VCIP D
Sbjct: 170 GATLLRDIPASAAYLSVYEYLKKKFSGEGAQRT-LSPGATLMAGGLAGIANWGVCIPADV 228
Query: 367 LKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSL 543
LKSRLQTAPEGKYP G+R V RE++ EG L++G PV++RAFPANAACF G E++L
Sbjct: 229 LKSRLQTAPEGKYPDGIRGVLREVLREEGPRALFKGFWPVMLRAFPANAACFFGLELTL 287
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Frame = +1
Query: 313 AGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYPH--GLRSVFREMMANEGIVGLYRGV 477
AGG+ G C +V P DT+K R+QT P G+ P G + ++ EG LY+G+
Sbjct: 10 AGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYKGM 69
Query: 478 SPVLIRAFPANAACFLGYEV 537
+ L+ P A F G V
Sbjct: 70 AAPLVGVSPLFAVFFGGCAV 89
>sp|Q9VQG4|COLT_DROME Congested-like trachea protein
Length = 306
Score = 207 bits (527), Expect = 2e-53
Identities = 99/186 (53%), Positives = 133/186 (71%)
Frame = +1
Query: 4 IFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKG 183
IF AG SG+F+T IM PGERIK LLQ Q KY G D KLYKEGG+RS++KG
Sbjct: 118 IFVAGSFSGLFSTLIMAPGERIKVLLQTQQGQGGERKYNGMIDCAGKLYKEGGLRSVFKG 177
Query: 184 TAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPD 363
+ AT+LRD+PA G YF+ YE L+++ + + +S T+FAGG+AGM W++ +P D
Sbjct: 178 SCATMLRDLPANGLYFLVYEALQDVAKSKS-ETGQISTASTIFAGGVAGMAYWILGMPAD 236
Query: 364 TLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSL 543
LKSRLQ+APEG Y HG+RSVF++++ +G + LYRGV+P+++RAFPANAACF G E++
Sbjct: 237 VLKSRLQSAPEGTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFPANAACFFGIELAN 296
Query: 544 KLLNKV 561
K N V
Sbjct: 297 KFFNIV 302
Score = 67.8 bits (164), Expect = 2e-11
Identities = 52/182 (28%), Positives = 81/182 (44%), Gaps = 6/182 (3%)
Frame = +1
Query: 7 FAAGMLSGVFTTAIMTPGERIKCLLQV--QGASKEPPKYKGPGDVIRKLYKEGGIRSIYK 180
F G G+ P + IK LQ + A E P Y+G D K K G+R +YK
Sbjct: 19 FLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYK 78
Query: 181 GTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPP 360
G +A L P F Y K + + G+ + L+ + AG +G+ + L+ P
Sbjct: 79 GMSAPLTGVAPIFAMCFAGYALGKRL--QQRGEDAKLTYPQIFVAGSFSGLFSTLIMAPG 136
Query: 361 DTLKSRLQT----APEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLG 528
+ +K LQT E KY +G+ ++ G+ +++G ++R PAN FL
Sbjct: 137 ERIKVLLQTQQGQGGERKY-NGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLV 195
Query: 529 YE 534
YE
Sbjct: 196 YE 197
Score = 60.1 bits (144), Expect = 4e-09
Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 5/91 (5%)
Frame = +1
Query: 292 SPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEGI 456
+P ++ GG G+CN L P DT+K RLQT P G+ P G + + NEG+
Sbjct: 14 NPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGV 73
Query: 457 VGLYRGVSPVLIRAFPANAACFLGYEVSLKL 549
GLY+G+S L P A CF GY + +L
Sbjct: 74 RGLYKGMSAPLTGVAPIFAMCFAGYALGKRL 104
>sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine carrier-like protein (A BOUT
DE SOUFFLE) (Carnitine/acylcarnitine translocase-like
protein) (CAC-like protein)
Length = 300
Score = 126 bits (317), Expect = 4e-29
Identities = 76/190 (40%), Positives = 101/190 (53%), Gaps = 12/190 (6%)
Frame = +1
Query: 7 FAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPP---------KYKGPGDVIRKLYK-E 156
F AG +G + + P E IKC LQ QGA KY GP DV R + + E
Sbjct: 108 FVAGAGAGFAVSFLACPTELIKCRLQAQGALAGASTTSSVVAAVKYGGPMDVARHVLRSE 167
Query: 157 GGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMC 336
GG R ++KG T R++P T F +YE K L G D S L G + AGG+AG
Sbjct: 168 GGARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLAG-GSDTSSLGQGSLIMAGGVAGAS 226
Query: 337 NWLVCIPPDTLKSRLQTAPEGKYPH--GLRSVFREMMANEGIVGLYRGVSPVLIRAFPAN 510
W + P D +KS LQ + K P G FR+++ +EG+ GLY+G P + R+ PAN
Sbjct: 227 FWGIVYPTDVVKSVLQV-DDYKNPRYTGSMDAFRKILKSEGVKGLYKGFGPAMARSVPAN 285
Query: 511 AACFLGYEVS 540
AACFL YE++
Sbjct: 286 AACFLAYEMT 295
Score = 58.2 bits (139), Expect = 2e-08
Identities = 53/197 (26%), Positives = 79/197 (40%), Gaps = 16/197 (8%)
Frame = +1
Query: 10 AAGMLSGVFTTAIMTPGERIKCLLQVQG--ASKEPPKYKGPGDVIRKLYKEGGIRSIYKG 183
A+G + G + P + IK LQ Q A + P+Y G D +++ G + +YKG
Sbjct: 9 ASGTVGGAAQLVVGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKG 68
Query: 184 TAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPD 363
A L F ++ +L E G +S + AG AG + P +
Sbjct: 69 MGAPLATVAAFNAVLFTVRGQMEGLLRSEAGVPLTIS--QQFVAGAGAGFAVSFLACPTE 126
Query: 364 TLKSRLQT-------------APEGKYPHGLRSVFREMMANEGIV-GLYRGVSPVLIRAF 501
+K RLQ KY G V R ++ +EG GL++G+ P R
Sbjct: 127 LIKCRLQAQGALAGASTTSSVVAAVKYG-GPMDVARHVLRSEGGARGLFKGLFPTFAREV 185
Query: 502 PANAACFLGYEVSLKLL 552
P NA F YE + L
Sbjct: 186 PGNATMFAAYEAFKRFL 202
Score = 54.3 bits (129), Expect = 2e-07
Identities = 27/87 (31%), Positives = 45/87 (51%)
Frame = +1
Query: 1 AIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYK 180
++ AG ++G I+ P + +K +LQV P+Y G D RK+ K G++ +YK
Sbjct: 215 SLIMAGGVAGASFWGIVYPTDVVKSVLQVDDYKN--PRYTGSMDAFRKILKSEGVKGLYK 272
Query: 181 GTAATLLRDIPATGTYFMSYEWLKEIL 261
G + R +PA F++YE + L
Sbjct: 273 GFGPAMARSVPANAACFLAYEMTRSSL 299
>sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1 (Solute carrier family 25
member 15)
Length = 301
Score = 120 bits (300), Expect = 4e-27
Identities = 66/185 (35%), Positives = 95/185 (51%), Gaps = 4/185 (2%)
Frame = +1
Query: 10 AAGMLSGVFTTAIMTPGERIKCLLQ----VQGASKEPPKYKGPGDVIRKLYKEGGIRSIY 177
AAG + F ++ P E +KC LQ ++ + K V+++++++ G Y
Sbjct: 111 AAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFY 170
Query: 178 KGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIP 357
G ++TLLR++P +F YE L G K L P + +GG G+C WL P
Sbjct: 171 HGLSSTLLREVPGYFFFFGGYE-LSRSFFASGRSKDELGPVPLMLSGGFGGICLWLAVYP 229
Query: 358 PDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEV 537
D +KSR+Q GL F ++ NEGI LY G+ P +IRAFPAN A FL YE
Sbjct: 230 VDCIKSRIQVLSMTGKQTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEY 289
Query: 538 SLKLL 552
S KL+
Sbjct: 290 SRKLM 294
Score = 72.0 bits (175), Expect = 1e-12
Identities = 56/185 (30%), Positives = 83/185 (44%), Gaps = 9/185 (4%)
Frame = +1
Query: 13 AGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAA 192
AG G P + +K +Q P Y+G D K Y + G R YKGT+
Sbjct: 15 AGAAGGTACVLTGQPFDTMKVKMQTF-----PDLYRGLTDCCLKTYSQVGFRGFYKGTSP 69
Query: 193 TLLRDIPATGTYFMSYEWLKEILTPEGG--DKSHLSPGRTLFAGGIAGMCNWLVCIPPDT 366
L+ +I FM Y + ++++ G ++ LS + AG A LV P +
Sbjct: 70 ALIANIAENSVLFMCYGFCQQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAALVLCPTEL 129
Query: 367 LKSRLQTAPE----GKY---PHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFL 525
+K RLQT E GK + + SV +E+ +G +G Y G+S L+R P F
Sbjct: 130 VKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFG 189
Query: 526 GYEVS 540
GYE+S
Sbjct: 190 GYELS 194
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/85 (31%), Positives = 39/85 (45%)
Frame = +1
Query: 307 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 486
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 487 LIRAFPANAACFLGYEVSLKLLNKV 561
LI N+ F+ Y +++ KV
Sbjct: 71 LIANIAENSVLFMCYGFCQQVVRKV 95
>sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1 (Solute carrier family 25,
member 15)
Length = 301
Score = 118 bits (296), Expect = 1e-26
Identities = 66/185 (35%), Positives = 93/185 (50%), Gaps = 4/185 (2%)
Frame = +1
Query: 10 AAGMLSGVFTTAIMTPGERIKCLLQ----VQGASKEPPKYKGPGDVIRKLYKEGGIRSIY 177
AAG + F ++ P E +KC LQ ++ + K VI+ + ++ G Y
Sbjct: 111 AAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFY 170
Query: 178 KGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIP 357
G ++TLLR++P +F YE L G K L P + +GG+ G+C WL P
Sbjct: 171 HGLSSTLLREVPGYFFFFGGYE-LSRSFFASGRSKDELGPVPLMLSGGVGGICLWLAVYP 229
Query: 358 PDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEV 537
D +KSR+Q G F ++ NEGI LY G+ P +IRAFPAN A FL YE
Sbjct: 230 VDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEY 289
Query: 538 SLKLL 552
S KL+
Sbjct: 290 SRKLM 294
Score = 73.6 bits (179), Expect = 4e-13
Identities = 54/185 (29%), Positives = 82/185 (44%), Gaps = 9/185 (4%)
Frame = +1
Query: 13 AGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAA 192
AG G P + +K +Q P Y+G D K Y + G R YKGT+
Sbjct: 15 AGAAGGTACVLTGQPFDTMKVKMQTF-----PDLYRGLTDCCLKTYSQVGFRGFYKGTSP 69
Query: 193 TLLRDIPATGTYFMSYEWLKEILTPEGG--DKSHLSPGRTLFAGGIAGMCNWLVCIPPDT 366
L+ +I FM Y + ++++ G ++ LS + AG A LV P +
Sbjct: 70 ALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTEL 129
Query: 367 LKSRLQTAPE-------GKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFL 525
+K RLQT E K + + SV + ++ +G +G Y G+S L+R P F
Sbjct: 130 VKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFFFFG 189
Query: 526 GYEVS 540
GYE+S
Sbjct: 190 GYELS 194
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/85 (31%), Positives = 39/85 (45%)
Frame = +1
Query: 307 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 486
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 487 LIRAFPANAACFLGYEVSLKLLNKV 561
LI N+ F+ Y +++ KV
Sbjct: 71 LIANIAENSVLFMCYGFCQQVVRKV 95
>sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier
Length = 327
Score = 113 bits (282), Expect = 4e-25
Identities = 72/190 (37%), Positives = 101/190 (53%), Gaps = 7/190 (3%)
Frame = +1
Query: 10 AAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPG-DVIRKLYKEGGIRSIYKGT 186
AAG +S + TT + P ER+K +LQ KG + + KEGGI S++KG+
Sbjct: 146 AAGFISAIPTTLVTAPTERVKVVLQTSS--------KGSFIQAAKTIVKEGGIASLFKGS 197
Query: 187 AATLLRDIPATGTYFMSYEWLKEILT-----PEGGDKSHLSPGRTLFAGGIAGMCNWLVC 351
ATL RD P + YF SYE K L + G ++ AGGIAGM WL
Sbjct: 198 LATLARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAV 257
Query: 352 IPPDTLKSRLQTAPEGKYPHGLRSVFREM-MANEGIVGLYRGVSPVLIRAFPANAACFLG 528
P DT+K++LQ + + + S +E+ + GI G + G+ P L+R+FPANAA FLG
Sbjct: 258 FPIDTIKTKLQASSTRQ---NMLSATKEIYLQRGGIKGFFPGLGPALLRSFPANAATFLG 314
Query: 529 YEVSLKLLNK 558
E++ L K
Sbjct: 315 VEMTHSLFKK 324
Score = 47.4 bits (111), Expect = 3e-05
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 7/91 (7%)
Frame = +1
Query: 301 RTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREM-------MANEGIV 459
++ AGG+ G+C P D +K R Q H + ++ +E + +
Sbjct: 37 KSFVAGGVGGVCAVFTGHPFDLIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLFTNSVK 96
Query: 460 GLYRGVSPVLIRAFPANAACFLGYEVSLKLL 552
G Y+GV P L+ P A F GY+V KL+
Sbjct: 97 GFYKGVIPPLLGVTPIFAVSFWGYDVGKKLV 127
Score = 29.6 bits (65), Expect = 6.4
Identities = 21/88 (23%), Positives = 35/88 (39%), Gaps = 1/88 (1%)
Frame = +1
Query: 13 AGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLY-KEGGIRSIYKGTA 189
AG ++G+ + P + IK LQ + +++Y + GGI+ + G
Sbjct: 245 AGGIAGMSMWLAVFPIDTIKTKLQASSTRQNMLS------ATKEIYLQRGGIKGFFPGLG 298
Query: 190 ATLLRDIPATGTYFMSYEWLKEILTPEG 273
LLR PA F+ E + G
Sbjct: 299 PALLRSFPANAATFLGVEMTHSLFKKYG 326
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,637,381
Number of Sequences: 369166
Number of extensions: 1690324
Number of successful extensions: 5030
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4319
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4715
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4846822695
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)