Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_D09
(646 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O89013|OBRG_MOUSE Leptin receptor gene-related protein (... 127 2e-29
sp|O15243|OBRG_HUMAN Leptin receptor gene-related protein (... 127 2e-29
sp|O95214|LERL1_HUMAN Leptin receptor overlapping transcrip... 127 2e-29
sp|Q9CQ74|LERL1_MOUSE Leptin receptor overlapping transcrip... 125 7e-29
sp|Q9JLS8|OBRG_RAT Leptin receptor gene-related protein (OB... 125 7e-29
sp|Q18319|YTO2_CAEEL Hypothetical protein C30B5.2 in chromo... 96 6e-20
sp|P47111|VPS55_YEAST Vacuolar protein sorting protein 55 57 3e-08
sp|P03893|NU2M_MOUSE NADH-ubiquinone oxidoreductase chain 2... 34 0.37
sp|P0AA93|YPDA_ECOLI Inner membrane protein ypdA 33 0.63
sp|Q9NR82|CIQ5_HUMAN Potassium voltage-gated channel subfam... 31 2.4
>sp|O89013|OBRG_MOUSE Leptin receptor gene-related protein (OB-R gene related protein)
(OB-RGRP)
Length = 131
Score = 127 bits (320), Expect = 2e-29
Identities = 64/126 (50%), Positives = 86/126 (68%), Gaps = 2/126 (1%)
Frame = +3
Query: 6 LAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKK--YSDSSESSTLWDN 179
L+F ++G+TFL+L CALE Y +WPLFVL+F+ +SP+P IAK+ Y + SS +
Sbjct: 10 LSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKRVTYDSDATSSACREL 69
Query: 180 CIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGFFCLFGRENE 359
F T+ IVVS +GLP+VLA +IKWGAC LV+A N VIF TI GFF +FGR ++
Sbjct: 70 AYFFTTGIVVSAFGLPVVLARV----DVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDD 125
Query: 360 FSYSGW 377
FS+ W
Sbjct: 126 FSWEQW 131
>sp|O15243|OBRG_HUMAN Leptin receptor gene-related protein (OB-R gene related protein)
(OB-RGRP) (Leptin receptor overlapping transcript
protein)
Length = 131
Score = 127 bits (320), Expect = 2e-29
Identities = 63/126 (50%), Positives = 85/126 (67%), Gaps = 2/126 (1%)
Frame = +3
Query: 6 LAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKK--YSDSSESSTLWDN 179
L+F ++G+TFL+L CALE Y +WPLFVL+FH +SP+P IAK+ Y + SS +
Sbjct: 10 LSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFHAISPIPHFIAKRVTYDSDATSSACREL 69
Query: 180 CIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGFFCLFGRENE 359
F T+ IVVS +G P++LA +IKWGAC LV+A N VIF TI GFF +FGR ++
Sbjct: 70 AYFFTTGIVVSAFGFPVILARV----AVIKWGACGLVLAGNAVIFLTIQGFFLIFGRGDD 125
Query: 360 FSYSGW 377
FS+ W
Sbjct: 126 FSWEQW 131
>sp|O95214|LERL1_HUMAN Leptin receptor overlapping transcript-like 1
Length = 131
Score = 127 bits (320), Expect = 2e-29
Identities = 65/126 (51%), Positives = 89/126 (70%), Gaps = 2/126 (1%)
Frame = +3
Query: 6 LAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKKYSDSSE--SSTLWDN 179
L+F ++G+ FL+L CAL YNK+WPLFVL F+ LSP+P IA++ D ++ S+ +
Sbjct: 10 LSFGGAIGLMFLMLGCALPIYNKYWPLFVLFFYILSPIPYCIARRLVDDTDAMSNACKEL 69
Query: 180 CIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGFFCLFGRENE 359
IF+T+ IVVS +GLPIV A A L I+WGAC LV+ NTVIF+TILGFF +FG ++
Sbjct: 70 AIFLTTGIVVSAFGLPIVFARAHL----IEWGACALVLTGNTVIFATILGFFLVFGSNDD 125
Query: 360 FSYSGW 377
FS+ W
Sbjct: 126 FSWQQW 131
>sp|Q9CQ74|LERL1_MOUSE Leptin receptor overlapping transcript-like 1
Length = 131
Score = 125 bits (315), Expect = 7e-29
Identities = 63/126 (50%), Positives = 89/126 (70%), Gaps = 2/126 (1%)
Frame = +3
Query: 6 LAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKKYSDSSE--SSTLWDN 179
L+F ++G+ FL+L CAL YN++WPLFVL F+ LSP+P IA++ D ++ S+ +
Sbjct: 10 LSFGGAIGLMFLMLGCALPIYNQYWPLFVLFFYILSPIPYCIARRLVDDTDAMSNACKEL 69
Query: 180 CIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGFFCLFGRENE 359
IF+T+ IVVS +GLP+V A A L I+WGAC LV+ NTVIF+TILGFF +FG ++
Sbjct: 70 AIFLTTGIVVSAFGLPVVFARAHL----IEWGACALVLTGNTVIFATILGFFLVFGSNDD 125
Query: 360 FSYSGW 377
FS+ W
Sbjct: 126 FSWQQW 131
>sp|Q9JLS8|OBRG_RAT Leptin receptor gene-related protein (OB-R gene related protein)
(OB-RGRP)
Length = 131
Score = 125 bits (315), Expect = 7e-29
Identities = 62/126 (49%), Positives = 85/126 (67%), Gaps = 2/126 (1%)
Frame = +3
Query: 6 LAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKK--YSDSSESSTLWDN 179
L+F ++G+TFL+L CALE Y +WPLFVL+F+ +SP+P IAK+ Y + SS +
Sbjct: 10 LSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKRVTYDSDATSSACREL 69
Query: 180 CIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGFFCLFGRENE 359
F T+ IVVS +G P++LA +IKWGAC LV+A N VIF TI GFF +FGR ++
Sbjct: 70 AYFFTTGIVVSAFGFPVILARV----AVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDD 125
Query: 360 FSYSGW 377
FS+ W
Sbjct: 126 FSWEQW 131
>sp|Q18319|YTO2_CAEEL Hypothetical protein C30B5.2 in chromosome II
Length = 132
Score = 96.3 bits (238), Expect = 6e-20
Identities = 53/123 (43%), Positives = 79/123 (64%), Gaps = 1/123 (0%)
Frame = +3
Query: 6 LAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKKY-SDSSESSTLWDNC 182
LAF +G+TFL+L CAL +Y W P+FV+ F+ LSPVP LIA+++ D + ++ +
Sbjct: 10 LAFAGVVGLTFLVLGCALPRYGTWTPMFVITFYVLSPVPLLIARRFQEDMTGTNACIELA 69
Query: 183 IFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGFFCLFGRENEF 362
+FIT+ IV+S + LPIVLA A G I ACFLV + ++F TI+ +F L ++
Sbjct: 70 LFITTGIVISAFALPIVLAHA---GTIAN-SACFLVNTGSVIMFGTIIAYFYLHRDDDSG 125
Query: 363 SYS 371
S+S
Sbjct: 126 SWS 128
>sp|P47111|VPS55_YEAST Vacuolar protein sorting protein 55
Length = 140
Score = 57.4 bits (137), Expect = 3e-08
Identities = 43/121 (35%), Positives = 66/121 (54%), Gaps = 7/121 (5%)
Frame = +3
Query: 12 FLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLI---AKKY--SD--SSESSTL 170
FLA LG +IL+CAL ++ ++PLF +L L+P+P I KY SD S S+T
Sbjct: 18 FLA-LGFLLVILSCAL--FHNYYPLFDILIFLLAPIPNTIFNAGNKYHTSDFMSDSSNTG 74
Query: 171 WDNCIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGFFCLFGR 350
D F+T ++V SG LP+V L G + +C + M +I+S+I+ F F +
Sbjct: 75 QDLAHFLTGMLVTSGIALPVVFYHCQLIGHL----SCIMCMIGGLIIYSSIVIFKWFFKK 130
Query: 351 E 353
+
Sbjct: 131 D 131
>sp|P03893|NU2M_MOUSE NADH-ubiquinone oxidoreductase chain 2 (NADH dehydrogenase subunit
2)
Length = 345
Score = 33.9 bits (76), Expect = 0.37
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 6/102 (5%)
Frame = +3
Query: 54 ALEQYNKWWPLFVLLFHFLSPVPCLIAKKYSDS---SESSTLWDNC---IFITSIIVVSG 215
A+ YN L L+ + + P +A ++S + S LW+ + + S++++S
Sbjct: 192 AILPYNPSLTLLNLMIYIILTAPMFMALMLNNSMTINSISLLWNKTPAMLTMISLMLLSL 251
Query: 216 YGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGFFCL 341
GLP PLTG + KW +M +N +I +T++ L
Sbjct: 252 GGLP------PLTGFLPKWIIITELMKNNCLIMATLMAMMAL 287
>sp|P0AA93|YPDA_ECOLI Inner membrane protein ypdA
Length = 565
Score = 33.1 bits (74), Expect = 0.63
Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Frame = -1
Query: 325 RIVENITVLLAITKKQAPHFMIGPVNGATAKTIGRP*PDTTIMLVINIQ--LSHNVELSD 152
R + N L A+ K PHF+ +N ++ R PDT L+ N+ L +N+EL D
Sbjct: 353 REMANKAELRALQSKINPHFLFNALNAISSSI--RLNPDTARQLIFNLSRYLRYNIELKD 410
Query: 151 ESE 143
+ +
Sbjct: 411 DEQ 413
>sp|Q9NR82|CIQ5_HUMAN Potassium voltage-gated channel subfamily KQT member 5
(Voltage-gated potassium channel subunit Kv7.5)
(Potassium channel alpha subunit KvLQT5) (KQT-like 5)
Length = 897
Score = 31.2 bits (69), Expect = 2.4
Identities = 14/55 (25%), Positives = 25/55 (45%)
Frame = +3
Query: 78 WPLFVLLFHFLSPVPCLIAKKYSDSSESSTLWDNCIFITSIIVVSGYGLPIVLAV 242
W F FL CLI +S E + L +C+ I +++ +GL ++ +
Sbjct: 90 WAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRI 144
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,425,185
Number of Sequences: 369166
Number of extensions: 1467552
Number of successful extensions: 3389
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3300
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3376
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5267491560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)