Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_A23
(329 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9XSK2|CD63_BOVIN CD63 antigen 47 1e-05
sp|Q28709|CD63_RABIT CD63 antigen 45 7e-05
sp|P28648|CD63_RAT CD63 antigen (AD1 antigen) 44 1e-04
sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated anti... 42 3e-04
sp|P41731|CD63_MOUSE CD63 antigen 40 0.001
sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane... 39 0.003
sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane... 39 0.004
sp|P62080|TSN5_MOUSE Tetraspanin-5 (Tspan-5) (Transmembrane... 39 0.005
sp|Q68VK5|TSN5_RAT Tetraspanin-5 (Tspan-5) (Transmembrane 4... 39 0.005
sp|P27701|CD82_HUMAN CD82 antigen (Inducible membrane prote... 38 0.006
>sp|Q9XSK2|CD63_BOVIN CD63 antigen
Length = 237
Score = 47.0 bits (110), Expect = 1e-05
Identities = 24/65 (36%), Positives = 35/65 (53%)
Frame = +3
Query: 3 PSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAF 182
P SCC IT C K T+GC+ K+ ++ + +V+ LGIAF EI +V A
Sbjct: 165 PDSCCVNITHNCGINFVVKDIHTEGCVEKIAAWLRKNVLVVVAAALGIAFVEILGIVLAC 224
Query: 183 CLCRN 197
CL ++
Sbjct: 225 CLVKS 229
>sp|Q28709|CD63_RABIT CD63 antigen
Length = 238
Score = 44.7 bits (104), Expect = 7e-05
Identities = 22/65 (33%), Positives = 34/65 (52%)
Frame = +3
Query: 3 PSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAF 182
P SCC +TS C K + +GC+ K+ + + +V LGIAF E+ +V A
Sbjct: 166 PDSCCVNVTSGCGVKFNVKDIYVEGCVEKIGLWLRKNVLVVAAAALGIAFVEVLGIVFAC 225
Query: 183 CLCRN 197
CL ++
Sbjct: 226 CLVKS 230
>sp|P28648|CD63_RAT CD63 antigen (AD1 antigen)
Length = 238
Score = 43.5 bits (101), Expect = 1e-04
Identities = 21/65 (32%), Positives = 33/65 (50%)
Frame = +3
Query: 3 PSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAF 182
P SCC IT C + T GC+ + ++ + LV G LGIAF E+ ++ +
Sbjct: 166 PDSCCINITVGCGNDFKESTIHTQGCVETIAAWLRKNVLLVAGAALGIAFVEVLGIIFSC 225
Query: 183 CLCRN 197
CL ++
Sbjct: 226 CLVKS 230
>sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated antigen ME491)
(Lysosome-associated membrane glycoprotein 3) (LAMP-3)
(Ocular melanoma-associated antigen) (OMA81H)
(Granulophysin) (Tetraspanin-30) (Tspan-30)
Length = 238
Score = 42.4 bits (98), Expect = 3e-04
Identities = 21/65 (32%), Positives = 33/65 (50%)
Frame = +3
Query: 3 PSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAF 182
P SCC +T C +K +GC+ K+ + + +V LGIAF E+ +V A
Sbjct: 166 PDSCCINVTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFAC 225
Query: 183 CLCRN 197
CL ++
Sbjct: 226 CLVKS 230
>sp|P41731|CD63_MOUSE CD63 antigen
Length = 238
Score = 40.4 bits (93), Expect = 0.001
Identities = 20/65 (30%), Positives = 31/65 (47%)
Frame = +3
Query: 3 PSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAF 182
P SCC IT C + T GC+ + + + LV LGIAF E+ ++ +
Sbjct: 166 PDSCCINITVGCGNDFKESTIHTQGCVETIAIWLRKNILLVAAAALGIAFVEVLGIIFSC 225
Query: 183 CLCRN 197
CL ++
Sbjct: 226 CLVKS 230
>sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6)
Length = 245
Score = 39.3 bits (90), Expect = 0.003
Identities = 20/70 (28%), Positives = 34/70 (48%)
Frame = +3
Query: 3 PSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAF 182
P SCC C+ K +GC K+ + ++ +V GI+ G+A F++ + A+
Sbjct: 174 PKSCCK--LEGCYPQRDADKVNEEGCFIKVMTTIESEMGVVAGISFGVACFQLIGIFLAY 231
Query: 183 CLCRNTVQHQ 212
CL R +Q
Sbjct: 232 CLSRAITNNQ 241
>sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6)
(T245 protein) (Tetraspanin TM4-D) (A15 homolog)
Length = 245
Score = 38.9 bits (89), Expect = 0.004
Identities = 20/70 (28%), Positives = 33/70 (47%)
Frame = +3
Query: 3 PSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAF 182
P SCC C K +GC K+ + ++ +V GI+ G+A F++ + A+
Sbjct: 174 PKSCCK--LEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAY 231
Query: 183 CLCRNTVQHQ 212
CL R +Q
Sbjct: 232 CLSRAITNNQ 241
>sp|P62080|TSN5_MOUSE Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9)
(Tetraspan NET-4)
sp|P62079|TSN5_HUMAN Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9)
(Tetraspan NET-4)
Length = 268
Score = 38.5 bits (88), Expect = 0.005
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 16/83 (19%)
Frame = +3
Query: 3 PSSCC------DPITSPCWELGYDKKA----------FTDGCIPKMFSYAKTYFPLVIGI 134
P SCC D I + C GYD + +T GC+P+ + + +V GI
Sbjct: 183 PFSCCTKDPAEDVINTQC---GYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGI 239
Query: 135 TLGIAFFEIFVVVCAFCLCRNTV 203
+GIA +IF CL +N V
Sbjct: 240 FIGIALLQIF----GICLAQNLV 258
>sp|Q68VK5|TSN5_RAT Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9)
Length = 268
Score = 38.5 bits (88), Expect = 0.005
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 16/83 (19%)
Frame = +3
Query: 3 PSSCC------DPITSPCWELGYDKKA----------FTDGCIPKMFSYAKTYFPLVIGI 134
P SCC D I + C GYD + +T GC+P+ + + +V GI
Sbjct: 183 PFSCCTKDPAEDVINTQC---GYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGI 239
Query: 135 TLGIAFFEIFVVVCAFCLCRNTV 203
+GIA +IF CL +N V
Sbjct: 240 FIGIALLQIF----GICLAQNLV 258
>sp|P27701|CD82_HUMAN CD82 antigen (Inducible membrane protein R2) (C33 antigen) (IA4)
(Metastasis suppressor Kangai 1) (Suppressor of
tumorigenicity-6) (Tetraspanin-27) (Tspan-27)
Length = 267
Score = 38.1 bits (87), Expect = 0.006
Identities = 13/48 (27%), Positives = 30/48 (62%)
Frame = +3
Query: 54 DKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 197
D + +GC+ K+ ++ + +++G+ +G+A E+ +V + CLCR+
Sbjct: 208 DWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRH 255
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,385,929
Number of Sequences: 369166
Number of extensions: 709589
Number of successful extensions: 1773
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1747
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1773
length of database: 68,354,980
effective HSP length: 78
effective length of database: 53,945,650
effective search space used: 1672315150
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)