Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_P23
(719 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q01105|SET_HUMAN SET protein (Phosphatase 2A inhibitor I... 154 2e-37
sp|Q9EQU5|SET_MOUSE SET protein (Phosphatase 2A inhibitor I... 154 2e-37
sp|Q63945|SET_RAT SET protein (Phosphatase 2A inhibitor I2P... 154 2e-37
sp|P53997|SET_DROME SET protein 147 2e-35
sp|Q18240|SPR2_CAEEL Suppressor of presenilin 2 139 8e-33
sp|O88852|TSYL1_MOUSE Testis-specific Y-encoded-like protei... 107 3e-23
sp|Q9H0U9|TSYL1_HUMAN Testis-specific Y-encoded-like protei... 105 9e-23
sp|Q9UJ04|TSYL4_HUMAN Testis-specific Y-encoded-like protei... 105 9e-23
sp|P13825|ASP_PLAFS Aspartic acid-rich protein precursor 104 3e-22
sp|Q8VD63|TSYL4_MOUSE Testis-specific Y-encoded-like protei... 101 2e-21
>sp|Q01105|SET_HUMAN SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I) (HLA-DR
associated protein II) (PHAPII) (Inhibitor of granzyme
A-activated DNase) (IGAAD)
Length = 290
Score = 154 bits (389), Expect = 2e-37
Identities = 76/169 (44%), Positives = 102/169 (60%), Gaps = 1/169 (0%)
Frame = +1
Query: 1 EVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEE 180
+VE+K+N+ RQP FQ+R+ LI IPNFW+ NHPQ+ L+ E DE+ L LT ++V E
Sbjct: 68 KVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTE 127
Query: 181 FDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESL 357
F+DIKSG++I F N YF N ++K H+ ES + + + WK GK+ K +++
Sbjct: 128 FEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQ 187
Query: 358 NXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 504
N P SF WFT ELGEVIKDD+WPNPLQYYL
Sbjct: 188 N--KASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYL 234
>sp|Q9EQU5|SET_MOUSE SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I)
Length = 289
Score = 154 bits (389), Expect = 2e-37
Identities = 76/169 (44%), Positives = 102/169 (60%), Gaps = 1/169 (0%)
Frame = +1
Query: 1 EVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEE 180
+VE+K+N+ RQP FQ+R+ LI IPNFW+ NHPQ+ L+ E DE+ L LT ++V E
Sbjct: 67 KVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTE 126
Query: 181 FDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESL 357
F+DIKSG++I F N YF N ++K H+ ES + + + WK GK+ K +++
Sbjct: 127 FEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQ 186
Query: 358 NXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 504
N P SF WFT ELGEVIKDD+WPNPLQYYL
Sbjct: 187 N--KASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYL 233
>sp|Q63945|SET_RAT SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I) (Liver
regeneration-related protein LRRGR00002)
Length = 289
Score = 154 bits (389), Expect = 2e-37
Identities = 76/169 (44%), Positives = 102/169 (60%), Gaps = 1/169 (0%)
Frame = +1
Query: 1 EVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEE 180
+VE+K+N+ RQP FQ+R+ LI IPNFW+ NHPQ+ L+ E DE+ L LT ++V E
Sbjct: 67 KVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTE 126
Query: 181 FDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESL 357
F+DIKSG++I F N YF N ++K H+ ES + + + WK GK+ K +++
Sbjct: 127 FEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQ 186
Query: 358 NXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 504
N P SF WFT ELGEVIKDD+WPNPLQYYL
Sbjct: 187 N--KASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYL 233
>sp|P53997|SET_DROME SET protein
Length = 269
Score = 147 bits (372), Expect = 2e-35
Identities = 71/175 (40%), Positives = 104/175 (59%), Gaps = 7/175 (4%)
Frame = +1
Query: 1 EVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEE 180
+VE+K+N+ R+P +++R+ L+K IPNFW+ + NHPQ+ ++ E +E+ L +L L+VEE
Sbjct: 56 KVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEE 115
Query: 181 FDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGESEIK-------TTCDPVDWKEGKNFVK 339
F+DIKSG++I F N YF N +TK H+ + +T P+ WKEGKN +K
Sbjct: 116 FEDIKSGYRINFHFDENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLK 175
Query: 340 SLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 504
L L +F WF+ + E+ E+IKDDLWPNPLQYYL
Sbjct: 176 LL---LTKPYGNKKKRNSEYKTFFDWFSDNTDPVNDEIAELIKDDLWPNPLQYYL 227
>sp|Q18240|SPR2_CAEEL Suppressor of presenilin 2
Length = 312
Score = 139 bits (350), Expect = 8e-33
Identities = 73/168 (43%), Positives = 94/168 (55%)
Frame = +1
Query: 1 EVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEE 180
+VE+ FNQKR P++++R L I NFW A NH L T I E EDLL +L L+V+E
Sbjct: 54 KVEQIFNQKRLPIYEKRKKLTTKIDNFWQTAFLNHHLLSTAIPEEQEDLLAALRDLEVQE 113
Query: 181 FDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGESEIKTTCDPVDWKEGKNFVKSLNESLN 360
F+D++SGFKIIMTF PNEYF N ITKS H+ T ++WKE K
Sbjct: 114 FEDLRSGFKIIMTFDPNEYFTNEVITKSYHLQSESPSTEITEIEWKENKK---------- 163
Query: 361 XXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 504
+F++W T E+ EVIKDDL+ NPLQYY+
Sbjct: 164 ---PPFPEDGDSAHTFLEWLTYAALPDSDEIAEVIKDDLYVNPLQYYV 208
>sp|O88852|TSYL1_MOUSE Testis-specific Y-encoded-like protein 1 (TSPY-like 1)
Length = 379
Score = 107 bits (267), Expect = 3e-23
Identities = 58/171 (33%), Positives = 89/171 (52%), Gaps = 4/171 (2%)
Frame = +1
Query: 4 VEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEF 183
+E+KF + R+ ++R +I+ IP FW+ A NHPQL +I D ++L+ +TSL+V+E
Sbjct: 195 LEQKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQLSAMIRGRDAEMLRYVTSLEVKEL 254
Query: 184 DDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEG---KNFVKSLNE 351
K+G K F N YF N I K V S + + P+ W+ G ++F++ +
Sbjct: 255 RHPKTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRVVSLSTPIIWRRGHEPQSFIRRNQD 314
Query: 352 SLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 504
+ SF WF+ + E+IK+DLWPNPLQYYL
Sbjct: 315 LI--------------CSFFTWFSDHSLPESDRIAEIIKEDLWPNPLQYYL 351
>sp|Q9H0U9|TSYL1_HUMAN Testis-specific Y-encoded-like protein 1 (TSPY-like 1)
Length = 438
Score = 105 bits (263), Expect = 9e-23
Identities = 56/172 (32%), Positives = 90/172 (52%), Gaps = 4/172 (2%)
Frame = +1
Query: 1 EVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEE 180
++E KF + R+ ++R +I+ IP FW+ A NHPQL +I D ++L+ +T+L+V+E
Sbjct: 253 QLEHKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQLSAMIRGQDAEMLRYITNLEVKE 312
Query: 181 FDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEG---KNFVKSLN 348
++G K F N YF N I K V S + + P+ W+ G ++F++
Sbjct: 313 LRHPRTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRVVSLSTPIIWRRGHEPQSFIRRNQ 372
Query: 349 ESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 504
+ + SF WF+ ++ E+IK+DLWPNPLQYYL
Sbjct: 373 DLI--------------CSFFTWFSDHSLPESDKIAEIIKEDLWPNPLQYYL 410
>sp|Q9UJ04|TSYL4_HUMAN Testis-specific Y-encoded-like protein 4 (TSPY-like 4)
Length = 414
Score = 105 bits (263), Expect = 9e-23
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
Frame = +1
Query: 1 EVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEE 180
++E+KF + R+ Q+R+ +I+ IP FW+ A NHPQL +I+ DED+L+ + +L+VEE
Sbjct: 227 QLERKFGRMRRLHMQRRSFIIQNIPGFWVTAFRNHPQLSPMISGQDEDMLRYMINLEVEE 286
Query: 181 FDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESL 357
++G K F N YF N + K S + + P+ W G++ ++ +
Sbjct: 287 LKHPRAGCKFKFIFQGNPYFRNEGLVKEYERRSSGRVVSLSTPIRWHRGQDPQAHIHRNR 346
Query: 358 NXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 504
SF WF+ + E+IK +LWPNPLQYYL
Sbjct: 347 EGNTIP---------SFFNWFSDHSLLEFDRIAEIIKGELWPNPLQYYL 386
>sp|P13825|ASP_PLAFS Aspartic acid-rich protein precursor
Length = 253
Score = 104 bits (259), Expect = 3e-22
Identities = 53/172 (30%), Positives = 92/172 (53%), Gaps = 3/172 (1%)
Frame = +1
Query: 4 VEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEF 183
++K++++K++PLF++R +I+ IP FW N L HP L ++ E D D+L L LD+++
Sbjct: 38 IQKQYDEKKKPLFEKRDEIIQKIPGFWANTLRKHPALSDIVPE-DIDILNHLVKLDLKDN 96
Query: 184 DDIKSGFKIIMTF--SPNEYFNNTTITKSIHVGESEIKTT-CDPVDWKEGKNFVKSLNES 354
D +KI F E+ T+ K + ++ K C + WKEGKN + ++ +
Sbjct: 97 MDNNGSYKITFIFGEKAKEFMEPLTLVKHVTFDNNQEKVVECTRIKWKEGKNPIAAVTHN 156
Query: 355 LNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYLAV 510
+ S +WFT+D ++GE+I+ ++W NPL YYL +
Sbjct: 157 RSDLDNEIPKW-----SIFEWFTTDELQDKPDVGELIRREIWHNPLSYYLGL 203
>sp|Q8VD63|TSYL4_MOUSE Testis-specific Y-encoded-like protein 4 (TSPY-like 4)
Length = 406
Score = 101 bits (251), Expect = 2e-21
Identities = 53/169 (31%), Positives = 84/169 (49%), Gaps = 1/169 (0%)
Frame = +1
Query: 1 EVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEE 180
++E+KF + R+ Q+R+ +I+ IP FW+ A NHPQL +I+ DED+++ + +L+VEE
Sbjct: 219 QLERKFGRMRRLHMQRRSFIIQNIPGFWVTAFRNHPQLSPMISGQDEDMMRYMINLEVEE 278
Query: 181 FDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESL 357
+ G K F N YF N + K S + + P+ W G+ ++ +
Sbjct: 279 LKQPRVGCKFKFIFQSNPYFRNEGLVKEYERRSSGRVVSLSTPIRWHRGQEPQAHIHRNR 338
Query: 358 NXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLWPNPLQYYL 504
SF WF+ + E+IK +LW NPLQYYL
Sbjct: 339 EGNTIP---------SFFNWFSDHSLLEFDRIAEIIKGELWSNPLQYYL 378
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,189,608
Number of Sequences: 369166
Number of extensions: 1197071
Number of successful extensions: 3074
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2982
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3041
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6413660220
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)