Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_L21
(841 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9V3C0|ABS_DROME DEAD-box protein abstrakt 358 1e-98
sp|Q9UJV9|DDX41_HUMAN Probable ATP-dependent helicase DDX41... 354 1e-97
sp|Q91VN6|DDX41_MOUSE Probable ATP-dependent helicase DDX41... 353 3e-97
sp|O13370|DED1_SCHPO ATP-dependent RNA helicase ded1 179 1e-44
sp|P24784|DBP1_YEAST Probable ATP-dependent RNA helicase DB... 178 1e-44
sp|P06634|DED1_YEAST Probable ATP-dependent RNA helicase DED1 175 1e-43
sp|P24346|AN3_XENLA Putative ATP-dependent RNA helicase An3 168 1e-41
sp|P16381|PL10_MOUSE Putative ATP-dependent RNA helicase PL10 168 1e-41
sp|Q62095|DDX3Y_MOUSE DEAD-box protein 3, Y-chromosomal (DE... 166 1e-40
sp|P09052|VASA_DROME Vasa protein (Antigen Mab46F11) 166 1e-40
>sp|Q9V3C0|ABS_DROME DEAD-box protein abstrakt
Length = 619
Score = 358 bits (918), Expect = 1e-98
Identities = 179/284 (63%), Positives = 222/284 (78%), Gaps = 5/284 (1%)
Frame = +2
Query: 2 YLVLDEADRMIDMGFEEEIRTVFSYFRHQRQTLLFSATMPRKIQQFAKSALVKPXXXXXX 181
YL +DEADRMIDMGFEE++RT+FS+F+ QRQTLLFSATMP+KIQ FA+SALVKP
Sbjct: 336 YLCMDEADRMIDMGFEEDVRTIFSFFKGQRQTLLFSATMPKKIQNFARSALVKPVTINVG 395
Query: 182 XXXXXXLNIRQDVEYVKHEGKLQRLLDCLQKTKPPVIIFTEQKSEVDYIHEYLLIKGVDA 361
+N+ Q VEYVK E K+ LLDCLQKT PPV+IF E+K +VD IHEYLL+KGV+A
Sbjct: 396 RAGAASMNVTQQVEYVKQEAKVVYLLDCLQKTAPPVLIFAEKKQDVDCIHEYLLLKGVEA 455
Query: 362 ASIHSGMPQEERLRSIDSFKAGQKDVLVATDVAGKGLDFPKIRHVINYDMPDDIEIYVHR 541
+IH G QEER R++D+++ G+KDVLVATDVA KGLDFP ++HVINYDMPDDIE YVHR
Sbjct: 456 VAIHGGKDQEERSRAVDAYRVGKKDVLVATDVASKGLDFPNVQHVINYDMPDDIENYVHR 515
Query: 542 IGRTGRHKKRGVATTFINKSCNESILLDLKLLLQEANQTIPEFL--LAIETQGLVENQGD 715
IGRTGR +G+ATT INK+ +S+LLDLK LL E Q +P+FL LA ET+ + GD
Sbjct: 516 IGRTGRSNTKGLATTLINKTTEQSVLLDLKHLLIEGKQEVPDFLDELAPETEHQHLDLGD 575
Query: 716 I-GCSYCGGLGHRIIMCPKRESLQNRQAHDIGRKE--SHASADY 838
GC+YCGGLGHRI CPK E++QN+QA +IGR++ S+ +ADY
Sbjct: 576 SHGCTYCGGLGHRITECPKLEAVQNKQASNIGRRDYLSNTAADY 619
>sp|Q9UJV9|DDX41_HUMAN Probable ATP-dependent helicase DDX41 (DEAD-box protein 41) (DEAD-box
protein abstrakt homolog)
Length = 622
Score = 354 bits (909), Expect = 1e-97
Identities = 174/283 (61%), Positives = 221/283 (78%), Gaps = 4/283 (1%)
Frame = +2
Query: 2 YLVLDEADRMIDMGFEEEIRTVFSYFRHQRQTLLFSATMPRKIQQFAKSALVKPXXXXXX 181
YL LDEADRMIDMGFE +IRT+FSYF+ QRQTLLFSATMP+KIQ FAKSALVKP
Sbjct: 340 YLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVG 399
Query: 182 XXXXXXLNIRQDVEYVKHEGKLQRLLDCLQKTKPPVIIFTEQKSEVDYIHEYLLIKGVDA 361
L++ Q+VEYVK E K+ LL+CLQKT PPV+IF E+K++VD IHEYLL+KGV+A
Sbjct: 400 RAGAASLDVIQEVEYVKEEAKMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEA 459
Query: 362 ASIHSGMPQEERLRSIDSFKAGQKDVLVATDVAGKGLDFPKIRHVINYDMPDDIEIYVHR 541
+IH G QEER ++I++F+ G+KDVLVATDVA KGLDFP I+HVINYDMP++IE YVHR
Sbjct: 460 VAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHR 519
Query: 542 IGRTGRHKKRGVATTFINKSCNESILLDLKLLLQEANQTIPEFLLAIE--TQGLVENQGD 715
IGRTGR G+ATTFINK+C+ES+L+DLK LL EA Q +P L + + +++ G+
Sbjct: 520 IGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDIGGE 579
Query: 716 IGCSYCGGLGHRIIMCPKRESLQNRQAHDIGRKE--SHASADY 838
GC++CGGLGHRI CPK E++Q +Q +IGRK+ +H+S D+
Sbjct: 580 RGCAFCGGLGHRITDCPKLEAMQTKQVSNIGRKDYLAHSSMDF 622
>sp|Q91VN6|DDX41_MOUSE Probable ATP-dependent helicase DDX41 (DEAD-box protein 41)
Length = 622
Score = 353 bits (907), Expect = 3e-97
Identities = 174/283 (61%), Positives = 221/283 (78%), Gaps = 4/283 (1%)
Frame = +2
Query: 2 YLVLDEADRMIDMGFEEEIRTVFSYFRHQRQTLLFSATMPRKIQQFAKSALVKPXXXXXX 181
YL LDEADRMIDMGFE +IRT+FSYF+ QRQTLLFSATMP+KIQ FAKSALVKP
Sbjct: 340 YLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVG 399
Query: 182 XXXXXXLNIRQDVEYVKHEGKLQRLLDCLQKTKPPVIIFTEQKSEVDYIHEYLLIKGVDA 361
L++ Q+VEYVK E K+ LL+CLQKT PPV+IF E+K++VD IHEYLL+KGV+A
Sbjct: 400 RAGAASLDVIQEVEYVKEEAKMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEA 459
Query: 362 ASIHSGMPQEERLRSIDSFKAGQKDVLVATDVAGKGLDFPKIRHVINYDMPDDIEIYVHR 541
+IH G QEER ++I++F+ G+KDVLVATDVA KGLDFP I+HVINYDMP++IE YVHR
Sbjct: 460 VAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHR 519
Query: 542 IGRTGRHKKRGVATTFINKSCNESILLDLKLLLQEANQTIPEFLLAIE--TQGLVENQGD 715
IGRTGR G+ATTFINK+C+ES+L+DLK LL EA Q +P L + + +++ G+
Sbjct: 520 IGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPGLQVLHCGDESMLDIGGE 579
Query: 716 IGCSYCGGLGHRIIMCPKRESLQNRQAHDIGRKE--SHASADY 838
GC++CGGLGHRI CPK E++Q +Q +IGRK+ +H+S D+
Sbjct: 580 RGCAFCGGLGHRITDCPKLEAMQTKQVSNIGRKDYLAHSSMDF 622
>sp|O13370|DED1_SCHPO ATP-dependent RNA helicase ded1
Length = 636
Score = 179 bits (453), Expect = 1e-44
Identities = 108/244 (44%), Positives = 139/244 (56%), Gaps = 7/244 (2%)
Frame = +2
Query: 2 YLVLDEADRMIDMGFEEEIRTVFSYFR----HQRQTLLFSATMPRKIQQFAKSALVKPXX 169
+LVLDEADRM+DMGFE +IR + +RQTL+FSAT PR IQ A+ L
Sbjct: 332 FLVLDEADRMLDMGFEPQIRHIVEGADMTSVEERQTLMFSATFPRDIQLLARDFLKDYVF 391
Query: 170 XXXXXXXXXXLNIRQDVEYVKHEGKLQRLLDCLQKTKPP---VIIFTEQKSEVDYIHEYL 340
NI Q V +V+ K LLD L T PP +IF E K D + +YL
Sbjct: 392 LSVGRVGSTSENITQKVVHVEDSEKRSYLLDILH-TLPPEGLTLIFVETKRMADTLTDYL 450
Query: 341 LIKGVDAASIHSGMPQEERLRSIDSFKAGQKDVLVATDVAGKGLDFPKIRHVINYDMPDD 520
L A SIH Q ER R+++ F++G+ ++VAT VA +GLD P + HVINYD+P D
Sbjct: 451 LNSNFPATSIHGDRTQRERERALELFRSGRTSIMVATAVASRGLDIPNVTHVINYDLPTD 510
Query: 521 IEIYVHRIGRTGRHKKRGVATTFINKSCNESILLDLKLLLQEANQTIPEFLLAIETQGLV 700
I+ YVHRIGRTGR G A F N++ N+ I +L LLQEANQ P FL+A+ +
Sbjct: 511 IDDYVHRIGRTGRAGNTGQAVAFFNRN-NKGIAKELIELLQEANQECPSFLIAMARESSF 569
Query: 701 ENQG 712
G
Sbjct: 570 GGNG 573
>sp|P24784|DBP1_YEAST Probable ATP-dependent RNA helicase DBP1 (Helicase CA1)
Length = 617
Score = 178 bits (452), Expect = 1e-44
Identities = 106/235 (45%), Positives = 136/235 (57%), Gaps = 5/235 (2%)
Frame = +2
Query: 2 YLVLDEADRMIDMGFEEEIRTVFSYFR----HQRQTLLFSATMPRKIQQFAKSALVKPXX 169
YLVLDEADRM+DMGFE +IR + RQTL+FSAT P IQ A+ L
Sbjct: 314 YLVLDEADRMLDMGFEPQIRHIVEECDMPSVENRQTLMFSATFPVDIQHLARDFLDNYIF 373
Query: 170 XXXXXXXXXXLNIRQDVEYVKHEGKLQRLLDCLQ-KTKPPVIIFTEQKSEVDYIHEYLLI 346
NI Q + YV K LLD L + K +IF E K D + ++L++
Sbjct: 374 LSVGRVGSTSENITQRILYVDDMDKKSALLDLLSAEHKGLTLIFVETKRMADQLTDFLIM 433
Query: 347 KGVDAASIHSGMPQEERLRSIDSFKAGQKDVLVATDVAGKGLDFPKIRHVINYDMPDDIE 526
+ A +IH Q ER R++ +FKA D+LVAT VA +GLD P + HVINYD+P DI+
Sbjct: 434 QNFKATAIHGDRTQAERERALSAFKANVADILVATAVAARGLDIPNVTHVINYDLPSDID 493
Query: 527 IYVHRIGRTGRHKKRGVATTFINKSCNESILLDLKLLLQEANQTIPEFLLAIETQ 691
YVHRIGRTGR GVAT+F N S N++I+ L +L EANQ +P FL + Q
Sbjct: 494 DYVHRIGRTGRAGNTGVATSFFN-SNNQNIVKGLMEILNEANQEVPTFLSDLSRQ 547
>sp|P06634|DED1_YEAST Probable ATP-dependent RNA helicase DED1
Length = 604
Score = 175 bits (444), Expect = 1e-43
Identities = 107/253 (42%), Positives = 142/253 (56%), Gaps = 5/253 (1%)
Frame = +2
Query: 2 YLVLDEADRMIDMGFEEEIRTVFSYFRH----QRQTLLFSATMPRKIQQFAKSALVKPXX 169
YLVLDEADRM+DMGFE +IR + +RQTL+FSAT P IQ A+ L
Sbjct: 302 YLVLDEADRMLDMGFEPQIRHIVEDCDMTPVGERQTLMFSATFPADIQHLARDFLSDYIF 361
Query: 170 XXXXXXXXXXLNIRQDVEYVKHEGKLQRLLDCLQ-KTKPPVIIFTEQKSEVDYIHEYLLI 346
NI Q V YV+++ K LLD L T +IF E K D + ++L++
Sbjct: 362 LSVGRVGSTSENITQKVLYVENQDKKSALLDLLSASTDGLTLIFVETKRMADQLTDFLIM 421
Query: 347 KGVDAASIHSGMPQEERLRSIDSFKAGQKDVLVATDVAGKGLDFPKIRHVINYDMPDDIE 526
+ A +IH Q ER R++ +F++G +LVAT VA +GLD P + HVINYD+P D++
Sbjct: 422 QNFRATAIHGDRTQSERERALAAFRSGAATLLVATAVAARGLDIPNVTHVINYDLPSDVD 481
Query: 527 IYVHRIGRTGRHKKRGVATTFINKSCNESILLDLKLLLQEANQTIPEFLLAIETQGLVEN 706
YVHRIGRTGR G+AT F N S N +I+ L +L EANQ +P FL ++
Sbjct: 482 DYVHRIGRTGRAGNTGLATAFFN-SENSNIVKGLHEILTEANQEVPSFL----KDAMMSA 536
Query: 707 QGDIGCSYCGGLG 745
G S GG G
Sbjct: 537 PGSRSNSRRGGFG 549
>sp|P24346|AN3_XENLA Putative ATP-dependent RNA helicase An3
Length = 697
Score = 168 bits (426), Expect = 1e-41
Identities = 103/256 (40%), Positives = 143/256 (55%), Gaps = 8/256 (3%)
Frame = +2
Query: 2 YLVLDEADRMIDMGFEEEIRTVFSYF----RHQRQTLLFSATMPRKIQQFAKSALVKPXX 169
YLVLDEADRM+DMGFE +IR + + RQT++FSAT P++IQ A+ L +
Sbjct: 384 YLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRQTMMFSATFPKEIQILARDFLDEYIF 443
Query: 170 XXXXXXXXXXLNIRQDVEYVKHEGKLQRLLDCLQKTKPP--VIIFTEQKSEVDYIHEYLL 343
NI Q V +V+ K LLD L T ++F E K D + ++L
Sbjct: 444 LAVGRVGSTSENITQKVVWVEEMDKRSFLLDLLNATGKDSLTLVFVETKKGADALEDFLY 503
Query: 344 IKGVDAASIHSGMPQEERLRSIDSFKAGQKDVLVATDVAGKGLDFPKIRHVINYDMPDDI 523
+G SIH Q +R ++ F++G+ +LVAT VA +GLD ++HVIN+D+P DI
Sbjct: 504 HEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDI 563
Query: 524 EIYVHRIGRTGRHKKRGVATTFINKSCNESILLDLKLLLQEANQTIPEFL--LAIETQGL 697
E YVHRIGRTGR G+AT+F N+ N +I DL LL EA Q +P +L +A E
Sbjct: 564 EEYVHRIGRTGRVGNLGLATSFFNEK-NINITKDLLDLLVEAKQEVPSWLENMAYEQHHK 622
Query: 698 VENQGDIGCSYCGGLG 745
++G + GG G
Sbjct: 623 SSSRGRSKSRFSGGFG 638
>sp|P16381|PL10_MOUSE Putative ATP-dependent RNA helicase PL10
Length = 660
Score = 168 bits (426), Expect = 1e-41
Identities = 103/258 (39%), Positives = 144/258 (55%), Gaps = 8/258 (3%)
Frame = +2
Query: 2 YLVLDEADRMIDMGFEEEIRTVFSYF----RHQRQTLLFSATMPRKIQQFAKSALVKPXX 169
YLVLDEADRM+DMGFE +IR + + R T++FSAT P++IQ A+ L +
Sbjct: 342 YLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIF 401
Query: 170 XXXXXXXXXXLNIRQDVEYVKHEGKLQRLLDCLQKTKPP--VIIFTEQKSEVDYIHEYLL 343
NI Q V +V+ K LLD L T +++F E K D + ++L
Sbjct: 402 LAVGRVGSTSENITQKVVWVEEADKRSFLLDLLNATGKDSLILVFVETKKGADSLEDFLY 461
Query: 344 IKGVDAASIHSGMPQEERLRSIDSFKAGQKDVLVATDVAGKGLDFPKIRHVINYDMPDDI 523
+G SIH Q +R ++ F++G+ +LVAT VA +GLD ++HVIN+D+P DI
Sbjct: 462 HEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDI 521
Query: 524 EIYVHRIGRTGRHKKRGVATTFINKSCNESILLDLKLLLQEANQTIPEFL--LAIETQGL 697
E YVHRIGRTGR G+AT+F N+ N +I DL LL EA Q +P +L +A E
Sbjct: 522 EEYVHRIGRTGRVGNLGLATSFFNER-NINITKDLLDLLVEAKQEVPSWLENMAFEHHYK 580
Query: 698 VENQGDIGCSYCGGLGHR 751
++G + GG G R
Sbjct: 581 GGSRGRSKSRFSGGFGAR 598
>sp|Q62095|DDX3Y_MOUSE DEAD-box protein 3, Y-chromosomal (DEAD-box RNA helicase DEAD2)
(mDEAD2) (D1Pas1-related sequence 1)
Length = 658
Score = 166 bits (419), Expect = 1e-40
Identities = 103/258 (39%), Positives = 143/258 (55%), Gaps = 8/258 (3%)
Frame = +2
Query: 2 YLVLDEADRMIDMGFEEEIRTVFSYF----RHQRQTLLFSATMPRKIQQFAKSALVKPXX 169
YLVLDEADRM+DMGFE +IR + + R T++FSAT P++IQ A+ L +
Sbjct: 342 YLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIF 401
Query: 170 XXXXXXXXXXLNIRQDVEYVKHEGKLQRLLDCLQKTKPP--VIIFTEQKSEVDYIHEYLL 343
NI Q V +V+ K LLD L T ++F E K D + +L
Sbjct: 402 LAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNATGKDSLTLVFVETKKGADSLENFLF 461
Query: 344 IKGVDAASIHSGMPQEERLRSIDSFKAGQKDVLVATDVAGKGLDFPKIRHVINYDMPDDI 523
+ SIH Q++R ++ F++G+K +LVAT VA +GLD ++HVIN+D+P DI
Sbjct: 462 QERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAARGLDISNVKHVINFDLPSDI 521
Query: 524 EIYVHRIGRTGRHKKRGVATTFINKSCNESILLDLKLLLQEANQTIPEFL--LAIETQGL 697
E YVHRIGRTGR G+AT+F N+ N +I DL LL EA Q +P +L +A E
Sbjct: 522 EEYVHRIGRTGRVGNLGLATSFFNER-NLNITKDLLDLLVEAKQEVPSWLESMAYEHHYK 580
Query: 698 VENQGDIGCSYCGGLGHR 751
++G + GG G R
Sbjct: 581 GSSRGRSKSRFSGGFGAR 598
>sp|P09052|VASA_DROME Vasa protein (Antigen Mab46F11)
Length = 661
Score = 166 bits (419), Expect = 1e-40
Identities = 89/226 (39%), Positives = 130/226 (57%), Gaps = 2/226 (0%)
Frame = +2
Query: 2 YLVLDEADRMIDMGFEEEIRTVFSY--FRHQRQTLLFSATMPRKIQQFAKSALVKPXXXX 175
++VLDEADRM+DMGF E++R + ++ R + QTL+FSAT P +IQ+ A L
Sbjct: 395 FVVLDEADRMLDMGFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAGEFLKNYVFVA 454
Query: 176 XXXXXXXXLNIRQDVEYVKHEGKLQRLLDCLQKTKPPVIIFTEQKSEVDYIHEYLLIKGV 355
+++Q + V K +L++ L + I+F E K D++ +L K
Sbjct: 455 IGIVGGACSDVKQTIYEVNKYAKRSKLIEILSEQADGTIVFVETKRGADFLASFLSEKEF 514
Query: 356 DAASIHSGMPQEERLRSIDSFKAGQKDVLVATDVAGKGLDFPKIRHVINYDMPDDIEIYV 535
SIH Q +R +++ FK G VL+AT VA +GLD I+HVINYDMP I+ YV
Sbjct: 515 PTTSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYV 574
Query: 536 HRIGRTGRHKKRGVATTFINKSCNESILLDLKLLLQEANQTIPEFL 673
HRIGRTGR G AT+F + + +I DL +L+ + QT+P+FL
Sbjct: 575 HRIGRTGRVGNNGRATSFFDPEKDRAIAADLVKILEGSGQTVPDFL 620
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,528,676
Number of Sequences: 369166
Number of extensions: 2048880
Number of successful extensions: 7602
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6926
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7315
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8197207050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)