Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_L09
(843 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9EQU5|SET_MOUSE SET protein (Phosphatase 2A inhibitor I... 191 2e-48
sp|Q63945|SET_RAT SET protein (Phosphatase 2A inhibitor I2P... 191 2e-48
sp|Q01105|SET_HUMAN SET protein (Phosphatase 2A inhibitor I... 190 5e-48
sp|P53997|SET_DROME SET protein 176 6e-44
sp|Q18240|SPR2_CAEEL Suppressor of presenilin 2 159 7e-39
sp|Q9UJ04|TSYL4_HUMAN Testis-specific Y-encoded-like protei... 120 4e-27
sp|O88852|TSYL1_MOUSE Testis-specific Y-encoded-like protei... 119 1e-26
sp|Q9H0U9|TSYL1_HUMAN Testis-specific Y-encoded-like protei... 118 2e-26
sp|P13825|ASP_PLAFS Aspartic acid-rich protein precursor 115 1e-25
sp|Q8VD63|TSYL4_MOUSE Testis-specific Y-encoded-like protei... 113 7e-25
>sp|Q9EQU5|SET_MOUSE SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I)
Length = 289
Score = 191 bits (486), Expect = 2e-48
Identities = 98/209 (46%), Positives = 130/209 (62%), Gaps = 1/209 (0%)
Frame = +2
Query: 5 KTESNGKVDQDQVLNSLIEKIDEVQSDIDKLNEQASEEILEVEKKFNQKRQPLFQQRANL 184
K+ S G ++ IE IDEVQ++ID+LNEQASEEIL+VE+K+N+ RQP FQ+R+ L
Sbjct: 27 KSASPGLPKGEKEQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSEL 86
Query: 185 IKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYF 364
I IPNFW+ NHPQ+ L+ E DE+ L LT ++V EF+DIKSG++I F N YF
Sbjct: 87 IAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYF 146
Query: 365 NNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQW 541
N ++K H+ ES + + + WK GK+ K +++ N P SF W
Sbjct: 147 ENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQN--KASRKRQHEEPESFFTW 204
Query: 542 FTSDIANSMVELGEVIKDDLWPNPLQYYL 628
FT ELGEVIKDD+WPNPLQYYL
Sbjct: 205 FTDHSDAGADELGEVIKDDIWPNPLQYYL 233
>sp|Q63945|SET_RAT SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I) (Liver
regeneration-related protein LRRGR00002)
Length = 289
Score = 191 bits (486), Expect = 2e-48
Identities = 98/209 (46%), Positives = 130/209 (62%), Gaps = 1/209 (0%)
Frame = +2
Query: 5 KTESNGKVDQDQVLNSLIEKIDEVQSDIDKLNEQASEEILEVEKKFNQKRQPLFQQRANL 184
K+ S G ++ IE IDEVQ++ID+LNEQASEEIL+VE+K+N+ RQP FQ+R+ L
Sbjct: 27 KSASPGLPKGEKEQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSEL 86
Query: 185 IKTIPNFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYF 364
I IPNFW+ NHPQ+ L+ E DE+ L LT ++V EF+DIKSG++I F N YF
Sbjct: 87 IAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYF 146
Query: 365 NNTTITKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQW 541
N ++K H+ ES + + + WK GK+ K +++ N P SF W
Sbjct: 147 ENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQN--KASRKRQHEEPESFFTW 204
Query: 542 FTSDIANSMVELGEVIKDDLWPNPLQYYL 628
FT ELGEVIKDD+WPNPLQYYL
Sbjct: 205 FTDHSDAGADELGEVIKDDIWPNPLQYYL 233
>sp|Q01105|SET_HUMAN SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I) (HLA-DR
associated protein II) (PHAPII) (Inhibitor of granzyme
A-activated DNase) (IGAAD)
Length = 290
Score = 190 bits (482), Expect = 5e-48
Identities = 95/192 (49%), Positives = 124/192 (64%), Gaps = 1/192 (0%)
Frame = +2
Query: 56 IEKIDEVQSDIDKLNEQASEEILEVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQ 235
IE IDEVQ++ID+LNEQASEEIL+VE+K+N+ RQP FQ+R+ LI IPNFW+ NHPQ
Sbjct: 45 IEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQ 104
Query: 236 LMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EI 412
+ L+ E DE+ L LT ++V EF+DIKSG++I F N YF N ++K H+ ES +
Sbjct: 105 VSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDP 164
Query: 413 KTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIK 592
+ + WK GK+ K +++ N P SF WFT ELGEVIK
Sbjct: 165 SSKSTEIKWKSGKDLTKRSSQTQN--KASRKRQHEEPESFFTWFTDHSDAGADELGEVIK 222
Query: 593 DDLWPNPLQYYL 628
DD+WPNPLQYYL
Sbjct: 223 DDIWPNPLQYYL 234
>sp|P53997|SET_DROME SET protein
Length = 269
Score = 176 bits (447), Expect = 6e-44
Identities = 86/198 (43%), Positives = 124/198 (62%), Gaps = 7/198 (3%)
Frame = +2
Query: 56 IEKIDEVQSDIDKLNEQASEEILEVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQ 235
+E+ID Q++ID LNE+ASEEIL+VE+K+N+ R+P +++R+ L+K IPNFW+ + NHPQ
Sbjct: 33 LEQIDACQNEIDALNEKASEEILKVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQ 92
Query: 236 LMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGESEIK 415
+ ++ E +E+ L +L L+VEEF+DIKSG++I F N YF N +TK H+ +
Sbjct: 93 VSGILDEEEEECLHALNKLEVEEFEDIKSGYRINFHFDENPYFENKVLTKEFHLNSAAAS 152
Query: 416 -------TTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVE 574
+T P+ WKEGKN +K L L +F WF+ + E
Sbjct: 153 ENGDWPASTSTPIKWKEGKNLLKLL---LTKPYGNKKKRNSEYKTFFDWFSDNTDPVNDE 209
Query: 575 LGEVIKDDLWPNPLQYYL 628
+ E+IKDDLWPNPLQYYL
Sbjct: 210 IAELIKDDLWPNPLQYYL 227
>sp|Q18240|SPR2_CAEEL Suppressor of presenilin 2
Length = 312
Score = 159 bits (403), Expect = 7e-39
Identities = 85/196 (43%), Positives = 113/196 (57%)
Frame = +2
Query: 41 VLNSLIEKIDEVQSDIDKLNEQASEEILEVEKKFNQKRQPLFQQRANLIKTIPNFWINAL 220
V LIE +D +Q +D ++E A+EE+L+VE+ FNQKR P++++R L I NFW A
Sbjct: 27 VKEKLIE-LDAIQHQLDVMSENAAEEVLKVEQIFNQKRLPIYEKRKKLTTKIDNFWQTAF 85
Query: 221 SNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVG 400
NH L T I E EDLL +L L+V+EF+D++SGFKIIMTF PNEYF N ITKS H+
Sbjct: 86 LNHHLLSTAIPEEQEDLLAALRDLEVQEFEDLRSGFKIIMTFDPNEYFTNEVITKSYHLQ 145
Query: 401 ESEIKTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELG 580
T ++WKE K +F++W T E+
Sbjct: 146 SESPSTEITEIEWKENKK-------------PPFPEDGDSAHTFLEWLTYAALPDSDEIA 192
Query: 581 EVIKDDLWPNPLQYYL 628
EVIKDDL+ NPLQYY+
Sbjct: 193 EVIKDDLYVNPLQYYV 208
>sp|Q9UJ04|TSYL4_HUMAN Testis-specific Y-encoded-like protein 4 (TSPY-like 4)
Length = 414
Score = 120 bits (302), Expect = 4e-27
Identities = 60/196 (30%), Positives = 102/196 (52%), Gaps = 1/196 (0%)
Frame = +2
Query: 44 LNSLIEKIDEVQSDIDKLNEQASEEILEVEKKFNQKRQPLFQQRANLIKTIPNFWINALS 223
+N+ ++ ++ + ++ +N QA L++E+KF + R+ Q+R+ +I+ IP FW+ A
Sbjct: 200 INNCMDSLEAIDQELSNVNAQADRAFLQLERKFGRMRRLHMQRRSFIIQNIPGFWVTAFR 259
Query: 224 NHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGE 403
NHPQL +I+ DED+L+ + +L+VEE ++G K F N YF N + K
Sbjct: 260 NHPQLSPMISGQDEDMLRYMINLEVEELKHPRAGCKFKFIFQGNPYFRNEGLVKEYERRS 319
Query: 404 S-EIKTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELG 580
S + + P+ W G++ ++ + SF WF+ +
Sbjct: 320 SGRVVSLSTPIRWHRGQDPQAHIHRNREGNTIP---------SFFNWFSDHSLLEFDRIA 370
Query: 581 EVIKDDLWPNPLQYYL 628
E+IK +LWPNPLQYYL
Sbjct: 371 EIIKGELWPNPLQYYL 386
>sp|O88852|TSYL1_MOUSE Testis-specific Y-encoded-like protein 1 (TSPY-like 1)
Length = 379
Score = 119 bits (297), Expect = 1e-26
Identities = 63/192 (32%), Positives = 100/192 (52%), Gaps = 4/192 (2%)
Frame = +2
Query: 65 IDEVQSDIDKLNEQASEEILEVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMT 244
++ +Q ++D +N QA +E+KF + R+ ++R +I+ IP FW+ A NHPQL
Sbjct: 174 LEAIQLELDTVNAQADRAFQHLEQKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQLSA 233
Query: 245 LITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EIKTT 421
+I D ++L+ +TSL+V+E K+G K F N YF N I K V S + +
Sbjct: 234 MIRGRDAEMLRYVTSLEVKELRHPKTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRVVSL 293
Query: 422 CDPVDWKEG---KNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIK 592
P+ W+ G ++F++ + + SF WF+ + E+IK
Sbjct: 294 STPIIWRRGHEPQSFIRRNQDLI--------------CSFFTWFSDHSLPESDRIAEIIK 339
Query: 593 DDLWPNPLQYYL 628
+DLWPNPLQYYL
Sbjct: 340 EDLWPNPLQYYL 351
>sp|Q9H0U9|TSYL1_HUMAN Testis-specific Y-encoded-like protein 1 (TSPY-like 1)
Length = 438
Score = 118 bits (295), Expect = 2e-26
Identities = 61/195 (31%), Positives = 103/195 (52%), Gaps = 4/195 (2%)
Frame = +2
Query: 56 IEKIDEVQSDIDKLNEQASEEILEVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQ 235
++ ++ +Q ++D +N QA ++E KF + R+ ++R +I+ IP FW+ A NHPQ
Sbjct: 230 MDPLEAIQLELDTVNAQADRAFQQLEHKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQ 289
Query: 236 LMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EI 412
L +I D ++L+ +T+L+V+E ++G K F N YF N I K V S +
Sbjct: 290 LSAMIRGQDAEMLRYITNLEVKELRHPRTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRV 349
Query: 413 KTTCDPVDWKEG---KNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGE 583
+ P+ W+ G ++F++ + + SF WF+ ++ E
Sbjct: 350 VSLSTPIIWRRGHEPQSFIRRNQDLI--------------CSFFTWFSDHSLPESDKIAE 395
Query: 584 VIKDDLWPNPLQYYL 628
+IK+DLWPNPLQYYL
Sbjct: 396 IIKEDLWPNPLQYYL 410
>sp|P13825|ASP_PLAFS Aspartic acid-rich protein precursor
Length = 253
Score = 115 bits (289), Expect = 1e-25
Identities = 59/190 (31%), Positives = 104/190 (54%), Gaps = 3/190 (1%)
Frame = +2
Query: 74 VQSDIDKLNEQASEEILEVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQLMTLIT 253
VQ DI++L+ + + E + ++K++++K++PLF++R +I+ IP FW N L HP L ++
Sbjct: 20 VQKDIEQLDIKCAHEQMNIQKQYDEKKKPLFEKRDEIIQKIPGFWANTLRKHPALSDIVP 79
Query: 254 EHDEDLLQSLTSLDVEEFDDIKSGFKIIMTF--SPNEYFNNTTITKSIHVGESEIKTT-C 424
E D D+L L LD+++ D +KI F E+ T+ K + ++ K C
Sbjct: 80 E-DIDILNHLVKLDLKDNMDNNGSYKITFIFGEKAKEFMEPLTLVKHVTFDNNQEKVVEC 138
Query: 425 DPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIKDDLW 604
+ WKEGKN + ++ + + S +WFT+D ++GE+I+ ++W
Sbjct: 139 TRIKWKEGKNPIAAVTHNRSDLDNEIPKW-----SIFEWFTTDELQDKPDVGELIRREIW 193
Query: 605 PNPLQYYLAV 634
NPL YYL +
Sbjct: 194 HNPLSYYLGL 203
>sp|Q8VD63|TSYL4_MOUSE Testis-specific Y-encoded-like protein 4 (TSPY-like 4)
Length = 406
Score = 113 bits (282), Expect = 7e-25
Identities = 57/192 (29%), Positives = 96/192 (50%), Gaps = 1/192 (0%)
Frame = +2
Query: 56 IEKIDEVQSDIDKLNEQASEEILEVEKKFNQKRQPLFQQRANLIKTIPNFWINALSNHPQ 235
++ ++ + ++ +N QA L++E+KF + R+ Q+R+ +I+ IP FW+ A NHPQ
Sbjct: 196 MDSLEAIDQELSNVNAQADRAFLQLERKFGRMRRLHMQRRSFIIQNIPGFWVTAFRNHPQ 255
Query: 236 LMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTITKSIHVGES-EI 412
L +I+ DED+++ + +L+VEE + G K F N YF N + K S +
Sbjct: 256 LSPMISGQDEDMMRYMINLEVEELKQPRVGCKFKFIFQSNPYFRNEGLVKEYERRSSGRV 315
Query: 413 KTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIANSMVELGEVIK 592
+ P+ W G+ ++ + SF WF+ + E+IK
Sbjct: 316 VSLSTPIRWHRGQEPQAHIHRNREGNTIP---------SFFNWFSDHSLLEFDRIAEIIK 366
Query: 593 DDLWPNPLQYYL 628
+LW NPLQYYL
Sbjct: 367 GELWSNPLQYYL 378
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,502,817
Number of Sequences: 369166
Number of extensions: 1475510
Number of successful extensions: 5010
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4782
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4972
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8245425915
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)