Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_J16
(905 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q37376|NU2M_ACACA NADH-ubiquinone oxidoreductase chain 2... 50 9e-06
sp|O99817|NU2M_RHISA NADH-ubiquinone oxidoreductase chain 2... 48 4e-05
sp|P24499|ATP6_TRYBB ATP synthase a chain (ATPase protein 6) 34 0.64
sp|P48902|NU2M_ALBCO NADH-ubiquinone oxidoreductase chain 2... 33 0.84
sp|P15577|NU2M_PARTE NADH-ubiquinone oxidoreductase chain 2... 32 1.9
sp|P18931|NU4M_DROME NADH-ubiquinone oxidoreductase chain 4... 32 1.9
sp|P56911|NUON2_RHIME NADH-quinone oxidoreductase chain N 2... 31 5.4
sp|O47478|NU6M_LOLBL NADH-ubiquinone oxidoreductase chain 6... 31 5.4
sp|O24982|LNT_HELPY Apolipoprotein N-acyltransferase (ALP N... 31 5.4
sp|P26361|CFTR_MOUSE Cystic fibrosis transmembrane conducta... 30 7.1
>sp|Q37376|NU2M_ACACA NADH-ubiquinone oxidoreductase chain 2 (NADH dehydrogenase subunit 2)
Length = 527
Score = 50.1 bits (118), Expect = 9e-06
Identities = 68/285 (23%), Positives = 109/285 (38%), Gaps = 28/285 (9%)
Frame = +2
Query: 107 IIHYFGGLSYNINSLF----YILAVLL-SDILVMSGFIVVSFDYLFFGFMLKLSFFPFLW 271
I + G LSY +LF Y+ +L S SGF++ F L GF+ KL PF
Sbjct: 212 IYGFTGLLSYTDLTLFLSEVYVTNFILDSSFFSFSGFLI-GFLLLTVGFLFKLGSAPFHM 270
Query: 272 LVPNLFLGMSYWLIGFLVFFHKAVIVXXXXXXXXXXXXXHVFLILLSIF-VSRLYLILNK 448
+P+++ G + +L K ++ VFL +F ++ L+ IL
Sbjct: 271 WMPDVYEGSPLLITAYLSTLPKISLIFVIFKLYYYVFF-EVFLFSQGLFTLTALFSILLG 329
Query: 449 DC-------LKSLIIWSSNIHCGXXXXXXXXXXXXVFGYMLIYLIFGIAFLIYLCYSF-- 601
LK ++ +S + G + YLI I +I L + F
Sbjct: 330 SIAAIYQVKLKRMLTYSMITNTGYLLLGLSFGDISGIYITIFYLISYIFIMIGLFFCFLS 389
Query: 602 -----------EYNYFSDVVGLDNGYGXXXXXXXXXXCRFPPMLG*VLKFTVYSTILKYT 748
N FS+++ ++ PP+LG KF ++ LKY
Sbjct: 390 LRDRSSGLLVKRINLFSNLLEVNPSLSFSIFILLFSIAGIPPLLGFYSKFFLFLFSLKYK 449
Query: 749 ILFFLILVNLFSTFGYLVVLRSFFVLLPY*NHFK--IYFYSLPFI 877
+ + IL +FS +R V L Y N I+ Y +PF+
Sbjct: 450 MYWMTILFVIFSVVSVFYYIR--LVKLMYFNRTTGWIFLYDIPFL 492
>sp|O99817|NU2M_RHISA NADH-ubiquinone oxidoreductase chain 2 (NADH dehydrogenase subunit
2)
Length = 313
Score = 47.8 bits (112), Expect = 4e-05
Identities = 50/256 (19%), Positives = 97/256 (37%), Gaps = 11/256 (4%)
Frame = +2
Query: 92 ISLFAIIHYFGGLSYNINSLFYILAVLLSDILVMSGFIVVSFDYLFFGFMLKLSFFPFLW 271
+S I++ F +YN ++I+ S + F + SF Y F L S
Sbjct: 31 MSFIPIMNDFKMKNYNSMITYFIIQSFSSSL-----FFISSFQYSLFNMELFFSLINISV 85
Query: 272 LVPNLFLGMSYWLIGF---LVFFHKAVIVXXXXXXXXXXXXXHVFLILLSIFVSRLYL-- 436
L+ + +WLI L F+ +++ + +++ +F+ L
Sbjct: 86 LIKLGMIPFHFWLIMISESLTFYSLLILLTIQKIIPLLIIEKFMNSLMIPLFIMSSLLAS 145
Query: 437 --ILNKDCLKSLIIWSSNIHCGXXXXXXXXXXXXVFGYMLIYLIFGIAFLIYLCYSFEYN 610
+ +K ++I+SS H G Y+++Y I I +I C +N
Sbjct: 146 IMAMKYKLIKQILIFSSISHQGWILCLIAKKMNFWVSYLMLYSII-IYSIIINCKEMNFN 204
Query: 611 YFSDVV--GLDNGYGXXXXXXXXXXCRFPPMLG*VLKFTVYSTILKYTILFFLILV--NL 778
D+ + + PP +G +K ++K ++F +IL+ +L
Sbjct: 205 KLCDLTKKKISSKMKNTMIMSMMSLAGMPPFIGFFMKIMAIFFLMKMNLIFMMILIISSL 264
Query: 779 FSTFGYLVVLRSFFVL 826
+ F YL +L F +
Sbjct: 265 INLFFYLRILTPLFFI 280
>sp|P24499|ATP6_TRYBB ATP synthase a chain (ATPase protein 6)
Length = 229
Score = 33.9 bits (76), Expect = 0.64
Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 1/116 (0%)
Frame = +2
Query: 542 YMLIYLIFGIAFLIYLCYSFEYNYFSDVVGLDNGYGXXXXXXXXXXCRFPPMLG*VLKF- 718
Y+ +YL+F I FL+Y+ + F + + D L N RF +L F
Sbjct: 78 YLNLYLLFCIVFLLYIAFLFLFCFLCDFF-LFNNLLVGDSFMDVFFIRF------LLCFL 130
Query: 719 TVYSTILKYTILFFLILVNLFSTFGYLVVLRSFFVLLPY*NHFKIYFYSLPFIIVF 886
+S + + F + NL S+ L++ FF + + ++ Y + FI VF
Sbjct: 131 ECFSLLCRCLSTFLRLFCNLLSSHFLLLMFFDFFYFIFVFFFYGVFCYFILFIFVF 186
>sp|P48902|NU2M_ALBCO NADH-ubiquinone oxidoreductase chain 2 (NADH dehydrogenase subunit
2)
Length = 307
Score = 33.5 bits (75), Expect = 0.84
Identities = 54/286 (18%), Positives = 110/286 (38%), Gaps = 19/286 (6%)
Frame = +2
Query: 92 ISLFAIIHYFGGLSYNINS----LFYILAVLLSDILVMSGFIVV-----SFDYLFFGF-- 238
ISL + Y+ + ++ +++++ + S +++++G + S+ YLF
Sbjct: 34 ISLLGFVSYYMLMKKIMSGEGIMMYFLIQSVSSTVMLLNGLYIFVNHASSYIYLFIFITM 93
Query: 239 -MLKLSFFPF-LWLVPNLFLGMSYWLIGFLVFFHKAVIVXXXXXXXXXXXXXHVFLILLS 412
MLK+ FP W++P ++ +SY IG + K V + + +LS
Sbjct: 94 LMLKIGMFPLHFWIIP-VYSKLSYLNIGIVGLLLKIVPMWILMHMGCITSEMLNLITMLS 152
Query: 413 IFVSRLYLILNKDCLKSLIIWSSNIHCGXXXXXXXXXXXXVFGYMLIYLIFGIAFLIYLC 592
+ ++ + K ++ ++ +F Y + Y + L++L
Sbjct: 153 VTSMLFGALIGMNLSKMRMVLGASTITHNGWLGMSCISGSLFKYFITYGFSLVILLVFLY 212
Query: 593 YSFEYNYFSDVVGLDNGYGXXXXXXXXXXCRFPPMLG*VLKFTV----YSTILKYTILFF 760
+ + ++ L PP + + K V T L + +L F
Sbjct: 213 LGDKMSISLSLLSLSG---------------LPPFMLFIGKINVLLMMMETNLWFIVLVF 257
Query: 761 LILVNLFSTFGYLVVLRSFFVLLP--Y*NHFKIYFYSLPFIIVFFG 892
IL + S YL FF+ + Y H+K+ + L + V FG
Sbjct: 258 AILSAVISLVYYLKFSVMFFMNMKNNYLKHYKMAMFLL--VNVTFG 301
>sp|P15577|NU2M_PARTE NADH-ubiquinone oxidoreductase chain 2 (NADH dehydrogenase subunit
2)
Length = 193
Score = 32.3 bits (72), Expect = 1.9
Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 14/86 (16%)
Frame = +2
Query: 689 PPMLG*VLKFTVYSTILKYTILFFLIL---VNLFSTFGYLVVLRSFF-----VLLPY*NH 844
PP+LG LKF ++ + T L F+++ N+ + F YL ++SF +L N
Sbjct: 96 PPLLGFFLKFLIFFFLFFKTNLAFILIFLGFNMATLFFYLSTVKSFVNRKQASVLNSFNF 155
Query: 845 F------KIYFYSLPFIIVFFG*FLL 904
F +YF++ + +FF F L
Sbjct: 156 FIRAELSFLYFFNFFYFFLFFAFFFL 181
>sp|P18931|NU4M_DROME NADH-ubiquinone oxidoreductase chain 4 (NADH dehydrogenase subunit
4)
Length = 446
Score = 32.3 bits (72), Expect = 1.9
Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 8/78 (10%)
Frame = +2
Query: 239 MLKLSFFPFLWLVPNLFLGMSYWLIGFLVFFHKAVIVXXXXXXXXXXXXXHVF------- 397
MLK+ FF L+L+P F+ YW++ ++FF + + +
Sbjct: 1 MLKIIFF-LLFLIPFCFINNMYWMVQIMMFFISFIFLLMNNFMNYWSEISYFLGCDMLSY 59
Query: 398 -LILLSIFVSRLYLILNK 448
LILLS+++ L L+ ++
Sbjct: 60 GLILLSLWICSLMLLASE 77
>sp|P56911|NUON2_RHIME NADH-quinone oxidoreductase chain N 2 (NADH dehydrogenase I, chain
N 2) (NDH-1, chain N 2)
Length = 479
Score = 30.8 bits (68), Expect = 5.4
Identities = 45/231 (19%), Positives = 87/231 (37%), Gaps = 21/231 (9%)
Frame = +2
Query: 203 IVVSFDYLFFGFMLKLSFFPFLWLVPNLFLGMSYWLIGFLVFFHKAV--IVXXXXXXXXX 376
++++ ++ G + K+ PF VP+++ G + F+ KA V
Sbjct: 206 LLLAVVFIVAGLVFKIGAVPFHMWVPDVYEGAPTTITAFMSVAPKAAGFAVILRVFLNPL 265
Query: 377 XXXXHVFLILLSIFVSRL----YLILNKDCLKSLIIWSSNIHCG----XXXXXXXXXXXX 532
+ ++I+ +I V+ + ++ L +D K L+ +SS H G
Sbjct: 266 VEASNAWIIVAAIAVATMALGSFVALVQDNFKRLLAYSSIAHAGFAIFGVVAGGQDGIAS 325
Query: 533 VFGYMLIYL-----IFGIAFLIYLCYSFEYNYFSDVVGLDN---GYGXXXXXXXXXXCRF 688
V Y+LIY IFG A ++ F D G G
Sbjct: 326 VMLYLLIYTFMNLGIFG-AVIMMRNGDFSGEVIEDYAGFAKFHPGLALLMLLYLFSLAGI 384
Query: 689 PPMLG*VLKFTVYSTILK---YTILFFLILVNLFSTFGYLVVLRSFFVLLP 832
PP G KF V +++ + +L+++ S + Y+ ++ ++ P
Sbjct: 385 PPTAGFFAKFYVLVALVERGFVALAVIAVLLSVVSAYFYIRIVMVIYMREP 435
>sp|O47478|NU6M_LOLBL NADH-ubiquinone oxidoreductase chain 6 (NADH dehydrogenase subunit
6)
Length = 168
Score = 30.8 bits (68), Expect = 5.4
Identities = 22/100 (22%), Positives = 45/100 (45%)
Frame = +2
Query: 116 YFGGLSYNINSLFYILAVLLSDILVMSGFIVVSFDYLFFGFMLKLSFFPFLWLVPNLFLG 295
Y GG+ +F + L+ +++ +S + F ++FFGFM+ ++FF LV
Sbjct: 57 YVGGMLV----MFMYVISLIPNLIFLSNKVFAYFFFIFFGFMM-MNFFVMKELVSVEVKS 111
Query: 296 MSYWLIGFLVFFHKAVIVXXXXXXXXXXXXXHVFLILLSI 415
MS + G++ +I+ + +L+S+
Sbjct: 112 MSLFDYGYMSMGGSGIIMLYDNFFCYVLLAVILLFVLISV 151
>sp|O24982|LNT_HELPY Apolipoprotein N-acyltransferase (ALP N-acyltransferase)
Length = 425
Score = 30.8 bits (68), Expect = 5.4
Identities = 20/78 (25%), Positives = 36/78 (46%), Gaps = 8/78 (10%)
Frame = +2
Query: 104 AIIHYFGGLSYNINSLFYILAVLLSDILVMSGFIVVSFDYLFFGFMLKLSF--------F 259
A++ Y+ LS+ + Y+L +++ I ++ G + Y + LSF F
Sbjct: 70 ALLFYWCALSFRYSDFTYLLPLIIVLIALVYGVLFYLLLYFENPYFRLLSFLGSSFIHPF 129
Query: 260 PFLWLVPNLFLGMSYWLI 313
F WLVP+ F S + +
Sbjct: 130 GFDWLVPDSFFSYSVFRV 147
>sp|P26361|CFTR_MOUSE Cystic fibrosis transmembrane conductance regulator (CFTR)
(cAMP-dependent chloride channel)
Length = 1476
Score = 30.4 bits (67), Expect = 7.1
Identities = 11/32 (34%), Positives = 22/32 (68%)
Frame = +2
Query: 716 FTVYSTILKYTILFFLILVNLFSTFGYLVVLR 811
F V+ ++L YT++ ++L +F+T + +VLR
Sbjct: 316 FVVFLSVLPYTVINGIVLRKIFTTISFCIVLR 347
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,375,495
Number of Sequences: 369166
Number of extensions: 1071608
Number of successful extensions: 3338
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3140
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3326
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9174518830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)