Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_I03
(876 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NQV7|PRDM9_HUMAN PR-domain zinc finger protein 9 90 7e-18
sp|Q9NQW5|PRDM7_HUMAN PR-domain zinc finger protein 7 90 9e-18
sp|Q9H4Q4|PRD12_HUMAN PR-domain zinc finger protein 12 69 1e-11
sp|Q9NQX0|PRDM6_HUMAN PR-domain zinc finger protein 6 67 5e-11
sp|Q9UKN5|PRDM4_HUMAN PR-domain zinc finger protein 4 64 7e-10
sp|Q13029|PRDM2_HUMAN PR-domain zinc finger protein 2 (Reti... 64 7e-10
sp|Q63755|PRDM2_RAT PR-domain zinc finger protein 2 (Retino... 63 9e-10
sp|Q9GZV8|PRD14_HUMAN PR-domain zinc finger protein 14 62 3e-09
sp|Q9HAZ2|PRD16_HUMAN PR-domain zinc finger protein 16 (Tra... 60 8e-09
sp|Q9NQX1|PRDM5_HUMAN PR-domain zinc finger protein 5 58 4e-08
>sp|Q9NQV7|PRDM9_HUMAN PR-domain zinc finger protein 9
Length = 689
Score = 90.1 bits (222), Expect = 7e-18
Identities = 54/118 (45%), Positives = 66/118 (55%), Gaps = 5/118 (4%)
Frame = +2
Query: 524 TLTTGLLIKKSKIPNAGLGVWTRKS-IVIGTTFGPYLGEIGFVKREKDYQFFKKSLNGYA 700
+L GL I S IP AGLGVW S + +G FGPY G I + + NGY+
Sbjct: 35 SLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAAN--------NGYS 86
Query: 701 WVVRENLD---GVETY-LVDANDSMRSNWLRYVNCARNAEEQNLVSIQYNGLIFYRAC 862
W+VR G Y VD D +NW+RYVNCAR+ EEQNLV+ QY+ IFYR C
Sbjct: 87 WLVRRACHFTKGRNCYEYVDGKDKSWANWMRYVNCARDDEEQNLVAFQYHRQIFYRTC 144
>sp|Q9NQW5|PRDM7_HUMAN PR-domain zinc finger protein 7
Length = 407
Score = 89.7 bits (221), Expect = 9e-18
Identities = 50/114 (43%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Frame = +2
Query: 524 TLTTGLLIKKSKIPNAGLGVWTRKS-IVIGTTFGPYLGEIGFVKREKDYQFFKKSLNGYA 700
+L GL I S IP AGLGVW S + +G FGPY G I + + +GY+
Sbjct: 35 SLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAAN--------SGYS 86
Query: 701 WVVRENLDGVETYLVDANDSMRSNWLRYVNCARNAEEQNLVSIQYNGLIFYRAC 862
W++ + + E VD D +NW+RYVNCAR+ EEQNLV+ QY+ IFYR C
Sbjct: 87 WLITKGRNCYE--YVDGKDKSSANWMRYVNCARDDEEQNLVAFQYHRQIFYRTC 138
>sp|Q9H4Q4|PRD12_HUMAN PR-domain zinc finger protein 12
Length = 367
Score = 69.3 bits (168), Expect = 1e-11
Identities = 40/111 (36%), Positives = 57/111 (51%)
Frame = +2
Query: 527 LTTGLLIKKSKIPNAGLGVWTRKSIVIGTTFGPYLGEIGFVKREKDYQFFKKSLNGYAWV 706
L ++I +S IP GLG++++ I GT GP+ G V + K N W
Sbjct: 84 LPAEVIIAQSSIPGEGLGIFSKTWIKAGTEMGPFTGR---VIAPEHVDICKN--NNLMWE 138
Query: 707 VRENLDGVETYLVDANDSMRSNWLRYVNCARNAEEQNLVSIQYNGLIFYRA 859
V N DG Y +DA+ +W+ Y+ CARN +EQNL +Q IFY+A
Sbjct: 139 VF-NEDGTVRYFIDASQEDHRSWMTYIKCARNEQEQNLEVVQIGTSIFYKA 188
>sp|Q9NQX0|PRDM6_HUMAN PR-domain zinc finger protein 6
Length = 608
Score = 67.4 bits (163), Expect = 5e-11
Identities = 35/106 (33%), Positives = 57/106 (53%)
Frame = +2
Query: 554 SKIPNAGLGVWTRKSIVIGTTFGPYLGEIGFVKREKDYQFFKKSLNGYAWVVRENLDGVE 733
S +P G+ + I GT GP+ G + + EK ++ + W + + DG
Sbjct: 266 STVPGLAYGICAAQRIQQGTWIGPFQGVL--LPPEKVQAGAVRNTQ-HLWEIYDQ-DGTL 321
Query: 734 TYLVDANDSMRSNWLRYVNCARNAEEQNLVSIQYNGLIFYRACVNI 871
+ +D + +S+W+RY+ CAR+ EQNL +QY IFYRAC++I
Sbjct: 322 QHFIDGGEPSKSSWMRYIRCARHCGEQNLTVVQYRSNIFYRACIDI 367
>sp|Q9UKN5|PRDM4_HUMAN PR-domain zinc finger protein 4
Length = 801
Score = 63.5 bits (153), Expect = 7e-10
Identities = 41/129 (31%), Positives = 67/129 (51%)
Frame = +2
Query: 467 EHGVVQCKCNNNEMKHVESTLTTGLLIKKSKIPNAGLGVWTRKSIVIGTTFGPYLGEIGF 646
EHG V + +L L++++S I A +GVWT ++I + T FGP +G+
Sbjct: 390 EHGPVTFVPDTPIESRARLSLPKQLVLRQS-IVGAEVGVWTGETIPVRTCFGPLIGQQSH 448
Query: 647 VKREKDYQFFKKSLNGYAWVVRENLDGVETYLVDANDSMRSNWLRYVNCARNAEEQNLVS 826
++ K++N + W + N GV + + D NW+ +V ARN EEQNLV+
Sbjct: 449 SMEVAEWT--DKAVN-HIWKIYHN--GVLEFCIITTDENECNWMMFVRKARNREEQNLVA 503
Query: 827 IQYNGLIFY 853
++G IF+
Sbjct: 504 YPHDGKIFF 512
>sp|Q13029|PRDM2_HUMAN PR-domain zinc finger protein 2 (Retinoblastoma protein-interacting
zinc-finger protein) (Zinc finger protein RIZ)
(MTE-binding protein) (MTB-ZF) (GATA-3 binding protein
G3B)
Length = 1718
Score = 63.5 bits (153), Expect = 7e-10
Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 1/117 (0%)
Frame = +2
Query: 509 KHVESTLTTGLLIKKSKIPNAGLGVWTRKSIVIGTTFGPYLGEIGFVKREKDYQFFKKSL 688
+HV L + + S + +GVW K I+ G FGP++G+ K+++ +
Sbjct: 20 EHVLRGLPEEVRLFPSAVDKTRIGVWATKPILKGKKFGPFVGD----KKKRS----QVKN 71
Query: 689 NGYAW-VVRENLDGVETYLVDANDSMRSNWLRYVNCARNAEEQNLVSIQYNGLIFYR 856
N Y W V NL + +DA D + NWLRYVN A + EEQNL ++ N I+Y+
Sbjct: 72 NVYMWEVYYPNLGWM---CIDATDPEKGNWLRYVNWACSGEEQNLFPLEINRAIYYK 125
>sp|Q63755|PRDM2_RAT PR-domain zinc finger protein 2 (Retinoblastoma protein-interacting
zinc-finger protein) (Zinc finger protein RIZ)
Length = 1706
Score = 63.2 bits (152), Expect = 9e-10
Identities = 41/117 (35%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
Frame = +2
Query: 509 KHVESTLTTGLLIKKSKIPNAGLGVWTRKSIVIGTTFGPYLGEIGFVKREKDYQFFKKSL 688
+HV L + + S + +GVW K I+ G FGP++G+ ++K Q
Sbjct: 19 EHVLRGLPEEVRLFPSAVDKTRIGVWATKPILKGKKFGPFVGD-----KKKRSQVRN--- 70
Query: 689 NGYAW-VVRENLDGVETYLVDANDSMRSNWLRYVNCARNAEEQNLVSIQYNGLIFYR 856
N Y W V NL + +DA D + NWLRYVN A + EEQNL ++ N I+Y+
Sbjct: 71 NVYMWEVYYPNLGWM---CIDATDPEKGNWLRYVNWACSGEEQNLFPLEINRAIYYK 124
>sp|Q9GZV8|PRD14_HUMAN PR-domain zinc finger protein 14
Length = 571
Score = 61.6 bits (148), Expect = 3e-09
Identities = 36/98 (36%), Positives = 49/98 (50%)
Frame = +2
Query: 578 GVWTRKSIVIGTTFGPYLGEIGFVKREKDYQFFKKSLNGYAWVVRENLDGVETYLVDAND 757
GV+ I G FGP+ G++ K Y N W + E DG ++ +D
Sbjct: 267 GVFCSSFIAKGVRFGPFQGKVVNASEVKTY-----GDNSVMWEIFE--DGHLSHFIDGKG 319
Query: 758 SMRSNWLRYVNCARNAEEQNLVSIQYNGLIFYRACVNI 871
NW+ YVNCAR +EQNLV++Q G IFY +C I
Sbjct: 320 GT-GNWMSYVNCARFPKEQNLVAVQCQGHIFYESCKEI 356
>sp|Q9HAZ2|PRD16_HUMAN PR-domain zinc finger protein 16 (Transcription factor MEL1)
Length = 1276
Score = 60.1 bits (144), Expect = 8e-09
Identities = 34/117 (29%), Positives = 60/117 (51%), Gaps = 7/117 (5%)
Frame = +2
Query: 545 IKKSKIPNAGLGVWTRKSIVIGTTFGPYLGEIGFVKREKDYQFFK-------KSLNGYAW 703
+++S IP AGLGVW ++ + G GP + +E D+ + + G
Sbjct: 86 LRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAAAKETDFGWEQILTDVEVSPQEGCIT 145
Query: 704 VVRENLDGVETYLVDANDSMRSNWLRYVNCARNAEEQNLVSIQYNGLIFYRACVNID 874
+ E+L G E + VDAN + +WL+Y+ A + ++QNL Q + I+Y+ +I+
Sbjct: 146 KISEDL-GSEKFCVDANQAGAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIE 201
>sp|Q9NQX1|PRDM5_HUMAN PR-domain zinc finger protein 5
Length = 630
Score = 57.8 bits (138), Expect = 4e-08
Identities = 37/113 (32%), Positives = 61/113 (53%), Gaps = 3/113 (2%)
Frame = +2
Query: 545 IKKSKIPNAGLGVWTRKSIVIGTTFGPYLGEIGF---VKREKDYQFFKKSLNGYAWVVRE 715
+K S++ + G+G++T + + G FGP+ GE + DY+ W VR
Sbjct: 12 LKSSRVQD-GMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLM--------WEVRG 62
Query: 716 NLDGVETYLVDANDSMRSNWLRYVNCARNAEEQNLVSIQYNGLIFYRACVNID 874
+ G Y++DA + SNWLR+V+ A + E++NL +IQ IFY A +I+
Sbjct: 63 S-KGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIE 114
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,900,004
Number of Sequences: 369166
Number of extensions: 2201872
Number of successful extensions: 5741
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5510
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5725
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8694177530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)