Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_G07
(891 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9P7C7|PRP11_SCHPO Probable ATP-dependent RNA helicase p... 181 2e-45
sp|P24784|DBP1_YEAST Probable ATP-dependent RNA helicase DB... 130 4e-30
sp|P09052|VASA_DROME Vasa protein (Antigen Mab46F11) 130 5e-30
sp|Q5RF43|DDX3Y_PONPY DEAD-box protein 3, Y-chromosomal 130 6e-30
sp|O00571|DDX3X_HUMAN DEAD-box protein 3, X-chromosomal (He... 129 8e-30
sp|P06634|DED1_YEAST Probable ATP-dependent RNA helicase DED1 129 8e-30
sp|P24346|AN3_XENLA Putative ATP-dependent RNA helicase An3 128 2e-29
sp|Q62167|DDX3X_MOUSE DEAD-box protein 3, X-chromosomal (DE... 127 3e-29
sp|Q5RC67|DDX23_PONPY Probable ATP-dependent RNA helicase D... 126 7e-29
sp|Q9BUQ8|DDX23_HUMAN Probable ATP-dependent RNA helicase D... 126 7e-29
>sp|Q9P7C7|PRP11_SCHPO Probable ATP-dependent RNA helicase prp11
Length = 1014
Score = 181 bits (459), Expect = 2e-45
Identities = 103/260 (39%), Positives = 159/260 (61%), Gaps = 3/260 (1%)
Frame = +2
Query: 5 IEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEF---KYRGKSL 175
+EA+A+K++K+P+E+ V G + V ++V Q V + E KF +L+ELL E + ++L
Sbjct: 613 MEALARKVLKKPVEITVGGRSVVASEVEQIVEVRPEESKFSRLLELLGELYNNQLDVRTL 672
Query: 176 VFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFRSGTVPVLIATSIAARGL 355
VFV+ QE+A L S+L +G+ + IHGG Q R+ + ++++G VLIATS+ ARGL
Sbjct: 673 VFVDRQESADALLSDLMKRGYTSNSIHGGKDQHDRDSTISDYKAGVFDVLIATSVVARGL 732
Query: 356 DVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLLKALRENGQ 535
DV L +VVNYDCPNH EDYVHR GRTGRAG+ G + TF+T +QE ++ KAL+ + Q
Sbjct: 733 DVKSLQLVVNYDCPNHMEDYVHRVGRTGRAGHTGVAVTFITPEQEKYAVDIAKALKMSKQ 792
Query: 536 EIQKELVDAYARYTERMVAEGKTIKAPSGFRGHGYKFDAAEAMKEKGKKLQELFKYCPEE 715
+ KEL +++ E++ A GK A GF G G E + K ++ + E+
Sbjct: 793 PVPKELQTLASQFLEKVKA-GKEKAAGGGFGGKGLS-RLDETRNAERKMQRKAYGEDEED 850
Query: 716 ITEEDEAVLEEMQLTSHRAS 775
+ E EA ++T +++
Sbjct: 851 VETEAEAKSPLEKITPEKST 870
>sp|P24784|DBP1_YEAST Probable ATP-dependent RNA helicase DBP1 (Helicase CA1)
Length = 617
Score = 130 bits (328), Expect = 4e-30
Identities = 68/185 (36%), Positives = 112/185 (60%)
Frame = +2
Query: 5 IEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFV 184
I+ +A+ + I + V ++ Q + +D+ DK L++LLS +++G +L+FV
Sbjct: 360 IQHLARDFLDNYIFLSVGRVGSTSENITQRILYVDDMDKKSALLDLLSA-EHKGLTLIFV 418
Query: 185 ETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFRSGTVPVLIATSIAARGLDVN 364
ET+ A L+ L Q F+ + IHG TQ +RE + F++ +L+AT++AARGLD+
Sbjct: 419 ETKRMADQLTDFLIMQNFKATAIHGDRTQAERERALSAFKANVADILVATAVAARGLDIP 478
Query: 365 DLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLLKALRENGQEIQ 544
++ V+NYD P+ +DYVHR GRTGRAGN G + +F S+ + ++ L++ L E QE+
Sbjct: 479 NVTHVINYDLPSDIDDYVHRIGRTGRAGNTGVATSFFNSNNQNIVKGLMEILNEANQEVP 538
Query: 545 KELVD 559
L D
Sbjct: 539 TFLSD 543
>sp|P09052|VASA_DROME Vasa protein (Antigen Mab46F11)
Length = 661
Score = 130 bits (327), Expect = 5e-30
Identities = 69/180 (38%), Positives = 115/180 (63%), Gaps = 1/180 (0%)
Frame = +2
Query: 5 IEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFV 184
I+ +A + +K + V + C+DV Q +Y +++ K KL+E+LSE ++VFV
Sbjct: 439 IQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVNKYAKRSKLIEILSE--QADGTIVFV 496
Query: 185 ETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFRSGTVPVLIATSIAARGLDVN 364
ET+ A L+S L+ + F + IHG Q +RE+ + +F++G++ VLIATS+A+RGLD+
Sbjct: 497 ETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIK 556
Query: 365 DLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQE-VMIGNLLKALRENGQEI 541
++ V+NYD P+ +DYVHR GRTGR GN G + +F +++ + +L+K L +GQ +
Sbjct: 557 NIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDPEKDRAIAADLVKILEGSGQTV 616
>sp|Q5RF43|DDX3Y_PONPY DEAD-box protein 3, Y-chromosomal
Length = 658
Score = 130 bits (326), Expect = 6e-30
Identities = 73/213 (34%), Positives = 118/213 (55%)
Frame = +2
Query: 5 IEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFV 184
I+ +A+ + E I + V ++ Q V +++ DK L++LL +LVFV
Sbjct: 387 IQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDLLGATGRDSLTLVFV 446
Query: 185 ETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFRSGTVPVLIATSIAARGLDVN 364
ET++ A L L H+G+ + IHG +Q REE + FRSG P+L+AT++AARGLD++
Sbjct: 447 ETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDIS 506
Query: 365 DLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLLKALRENGQEIQ 544
++ V+N+D P+ E+YVHR GRTGR GN G + +F + +LL L E QE+
Sbjct: 507 NVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVP 566
Query: 545 KELVDAYARYTERMVAEGKTIKAPSGFRGHGYK 643
L + + + + G++ + GF Y+
Sbjct: 567 SWLENMAYEHHYKGGSRGRSKRFSGGFGARDYR 599
>sp|O00571|DDX3X_HUMAN DEAD-box protein 3, X-chromosomal (Helicase-like protein 2) (HLP2)
(DEAD-box, X isoform)
Length = 662
Score = 129 bits (325), Expect = 8e-30
Identities = 77/215 (35%), Positives = 119/215 (55%), Gaps = 2/215 (0%)
Frame = +2
Query: 5 IEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFV 184
I+ +A+ + E I + V ++ Q V ++E+DK L++LL+ +LVFV
Sbjct: 389 IQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFV 448
Query: 185 ETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFRSGTVPVLIATSIAARGLDVN 364
ET++ A L L H+G+ + IHG +Q REE + FRSG P+L+AT++AARGLD++
Sbjct: 449 ETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDIS 508
Query: 365 DLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLLKALRENGQEIQ 544
++ V+N+D P+ E+YVHR GRTGR GN G + +F + +LL L E QE+
Sbjct: 509 NVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVP 568
Query: 545 KELVD-AYA-RYTERMVAEGKTIKAPSGFRGHGYK 643
L + AY Y K+ + GF Y+
Sbjct: 569 SWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYR 603
>sp|P06634|DED1_YEAST Probable ATP-dependent RNA helicase DED1
Length = 604
Score = 129 bits (325), Expect = 8e-30
Identities = 72/186 (38%), Positives = 107/186 (57%)
Frame = +2
Query: 5 IEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFV 184
I+ +A+ + + I + V ++ Q V ++ DK L++LLS G +L+FV
Sbjct: 348 IQHLARDFLSDYIFLSVGRVGSTSENITQKVLYVENQDKKSALLDLLSA-STDGLTLIFV 406
Query: 185 ETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFRSGTVPVLIATSIAARGLDVN 364
ET+ A L+ L Q F + IHG TQ +RE + FRSG +L+AT++AARGLD+
Sbjct: 407 ETKRMADQLTDFLIMQNFRATAIHGDRTQSERERALAAFRSGAATLLVATAVAARGLDIP 466
Query: 365 DLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLLKALRENGQEIQ 544
++ V+NYD P+ +DYVHR GRTGRAGN G + F S+ ++ L + L E QE+
Sbjct: 467 NVTHVINYDLPSDVDDYVHRIGRTGRAGNTGLATAFFNSENSNIVKGLHEILTEANQEVP 526
Query: 545 KELVDA 562
L DA
Sbjct: 527 SFLKDA 532
>sp|P24346|AN3_XENLA Putative ATP-dependent RNA helicase An3
Length = 697
Score = 128 bits (322), Expect = 2e-29
Identities = 76/213 (35%), Positives = 118/213 (55%)
Frame = +2
Query: 5 IEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFV 184
I+ +A+ + E I + V ++ Q V ++E DK L++LL+ +LVFV
Sbjct: 430 IQILARDFLDEYIFLAVGRVGSTSENITQKVVWVEEMDKRSFLLDLLNATGKDSLTLVFV 489
Query: 185 ETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFRSGTVPVLIATSIAARGLDVN 364
ET++ A L L H+G+ + IHG +Q REE + FRSG P+L+AT++AARGLD++
Sbjct: 490 ETKKGADALEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDIS 549
Query: 365 DLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLLKALRENGQEIQ 544
++ V+N+D P+ E+YVHR GRTGR GN G + +F + +LL L E QE+
Sbjct: 550 NVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNINITKDLLDLLVEAKQEVP 609
Query: 545 KELVDAYARYTERMVAEGKTIKAPSGFRGHGYK 643
L + + + G++ SG G G K
Sbjct: 610 SWLENMAYEQHHKSSSRGRSKSRFSG--GFGAK 640
>sp|Q62167|DDX3X_MOUSE DEAD-box protein 3, X-chromosomal (DEAD-box RNA helicase DEAD3)
(mDEAD3) (Embryonic RNA helicase) (D1Pas1-related
sequence 2)
Length = 662
Score = 127 bits (320), Expect = 3e-29
Identities = 75/215 (34%), Positives = 119/215 (55%), Gaps = 2/215 (0%)
Frame = +2
Query: 5 IEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFV 184
I+ +A+ + E I + V ++ Q V ++E DK L++LL+ +LVFV
Sbjct: 389 IQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNATGKDSLTLVFV 448
Query: 185 ETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFRSGTVPVLIATSIAARGLDVN 364
ET++ A L L H+G+ + IHG +Q REE + FRSG P+L+AT++AARGLD++
Sbjct: 449 ETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDIS 508
Query: 365 DLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLLKALRENGQEIQ 544
++ V+N+D P+ E+YVHR GRTGR GN G + +F + +LL L E QE+
Sbjct: 509 NVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVP 568
Query: 545 KELVDAYARYTERMVAEG--KTIKAPSGFRGHGYK 643
L + + + + G K+ + GF Y+
Sbjct: 569 SWLENMAFEHHYKGSSRGRSKSSRFSGGFGARDYR 603
>sp|Q5RC67|DDX23_PONPY Probable ATP-dependent RNA helicase DDX23 (DEAD-box protein 23)
Length = 820
Score = 126 bits (317), Expect = 7e-29
Identities = 61/175 (34%), Positives = 103/175 (58%)
Frame = +2
Query: 5 IEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFV 184
+E +A+ ++ P V + K V Q V+L+ E++K KL+ +L + + ++FV
Sbjct: 613 VERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQ-GFDPPIIIFV 671
Query: 185 ETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFRSGTVPVLIATSIAARGLDVN 364
++ +L+ +L G+ +HGG QE+RE + N ++G +L+AT +A RG+D+
Sbjct: 672 NQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQ 731
Query: 365 DLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLLKALREN 529
D+ MVVNYD + EDY+HR GRTGRAG G + TF+T + + L +A+ E+
Sbjct: 732 DVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILES 786
>sp|Q9BUQ8|DDX23_HUMAN Probable ATP-dependent RNA helicase DDX23 (DEAD-box protein 23) (100
kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog)
Length = 820
Score = 126 bits (317), Expect = 7e-29
Identities = 61/175 (34%), Positives = 103/175 (58%)
Frame = +2
Query: 5 IEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFV 184
+E +A+ ++ P V + K V Q V+L+ E++K KL+ +L + + ++FV
Sbjct: 613 VERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQ-GFDPPIIIFV 671
Query: 185 ETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFRSGTVPVLIATSIAARGLDVN 364
++ +L+ +L G+ +HGG QE+RE + N ++G +L+AT +A RG+D+
Sbjct: 672 NQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQ 731
Query: 365 DLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLLKALREN 529
D+ MVVNYD + EDY+HR GRTGRAG G + TF+T + + L +A+ E+
Sbjct: 732 DVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILES 786
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,655,702
Number of Sequences: 369166
Number of extensions: 1633747
Number of successful extensions: 6042
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5741
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5998
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8934348180
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)