Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_G05
(885 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein ... 152 9e-37
sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 ... 149 1e-35
sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 ... 147 3e-35
sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) 139 8e-33
sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) 139 1e-32
sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) 139 1e-32
sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein ... 108 2e-23
sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprote... 80 6e-15
sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprote... 80 6e-15
sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprote... 75 2e-13
>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding
protein PPTB-1)
Length = 531
Score = 152 bits (385), Expect = 9e-37
Identities = 72/133 (54%), Positives = 95/133 (71%)
Frame = +3
Query: 486 GNSNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVT 665
G NSV++V+NLN +R+ P +LFILFGVYGDVQRVKIL+NKK AL+Q DG A A++
Sbjct: 333 GAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMS 392
Query: 666 NLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYP 845
+LN L+GKP+R+ SKH ++ +P+ E Q L KDY NS LHRFK+ S+ QNI+P
Sbjct: 393 HLNGHKLHGKPIRITLSKHQNVQLPR-EGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFP 451
Query: 846 PGTVLHLAGLPDS 884
P LHL+ +P S
Sbjct: 452 PSATLHLSNIPPS 464
Score = 37.0 bits (84), Expect = 0.073
Identities = 20/45 (44%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Frame = +3
Query: 6 VTAHVAKLQLGGSNAFYGH-PVRIEFSTRKSLDIKHESDTGRDYT 137
V+A AKL L G N + +RI+FS SL++K+ +D RDYT
Sbjct: 232 VSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYT 276
>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 557
Score = 149 bits (376), Expect = 1e-35
Identities = 71/133 (53%), Positives = 94/133 (70%)
Frame = +3
Query: 486 GNSNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVT 665
G NSV++V+NLN +R+ P +LFILFGVY DVQRVKIL+NKK AL+Q DG A A++
Sbjct: 359 GAGNSVLLVSNLNPERVTPQSLFILFGVYCDVQRVKILFNKKENALVQMADGSQAQLAMS 418
Query: 666 NLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYP 845
+LN L+GKP+R+ SKH ++ +P+ E Q L KDY NS LHRFK+ S+ QNI+P
Sbjct: 419 HLNGHKLHGKPVRITLSKHQNVQLPR-EGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFP 477
Query: 846 PGTVLHLAGLPDS 884
P LHL+ +P S
Sbjct: 478 PSATLHLSNIPPS 490
Score = 37.0 bits (84), Expect = 0.073
Identities = 20/45 (44%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Frame = +3
Query: 6 VTAHVAKLQLGGSNAFYGH-PVRIEFSTRKSLDIKHESDTGRDYT 137
V+A AKL L G N + +RI+FS SL++K+ +D RDYT
Sbjct: 232 VSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYT 276
>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding
protein) (PYBP)
Length = 555
Score = 147 bits (372), Expect = 3e-35
Identities = 70/133 (52%), Positives = 94/133 (70%)
Frame = +3
Query: 486 GNSNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVT 665
G NSV++V+NLN +R+ P +LFILFGVYGDVQRVKIL+NKK AL++ DG A A++
Sbjct: 357 GAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVEMADGSQAQLAMS 416
Query: 666 NLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYP 845
+LN L+GK +R+ SKH S+ +P+ E Q L KDY +S LHRFK+ S+ QNI+P
Sbjct: 417 HLNGHKLHGKSVRITLSKHQSVQLPR-EGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFP 475
Query: 846 PGTVLHLAGLPDS 884
P LHL+ +P S
Sbjct: 476 PSATLHLSNIPPS 488
Score = 37.0 bits (84), Expect = 0.073
Identities = 20/45 (44%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Frame = +3
Query: 6 VTAHVAKLQLGGSNAFYGH-PVRIEFSTRKSLDIKHESDTGRDYT 137
V+A AKL L G N + +RI+FS SL++K+ +D RDYT
Sbjct: 231 VSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYT 275
>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1)
Length = 521
Score = 139 bits (351), Expect = 8e-33
Identities = 68/130 (52%), Positives = 87/130 (66%)
Frame = +3
Query: 495 NSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLN 674
NSV++V NLN D I P LFILFGVYGDV RVKI++NKK AL+Q D A A+ +L+
Sbjct: 326 NSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLS 385
Query: 675 NVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGT 854
LYGK +R SKH ++ +P+ E Q L KD+SNS LHRFK+ S+ QNI+PP
Sbjct: 386 GQRLYGKVLRATLSKHQAVQLPR-EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSA 444
Query: 855 VLHLAGLPDS 884
LHL+ +P S
Sbjct: 445 TLHLSNIPPS 454
Score = 37.7 bits (86), Expect = 0.043
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Frame = +3
Query: 6 VTAHVAKLQLGGSNAFYGH-PVRIEFSTRKSLDIKHESDTGRDYT 137
V AH AK+ L G N + +RI+FS SL++K+ +D RD+T
Sbjct: 199 VNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFT 243
>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1)
Length = 523
Score = 139 bits (350), Expect = 1e-32
Identities = 68/130 (52%), Positives = 87/130 (66%)
Frame = +3
Query: 495 NSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLN 674
NSV++V NLN D I P LFILFGVYGDV RVKI++NKK AL+Q D A A+ +L+
Sbjct: 328 NSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLS 387
Query: 675 NVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGT 854
LYGK +R SKH ++ +P+ E Q L KD+SNS LHRFK+ S+ QNI+PP
Sbjct: 388 GQRLYGKVLRATLSKHQAVQLPR-EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSA 446
Query: 855 VLHLAGLPDS 884
LHL+ +P S
Sbjct: 447 TLHLSNIPPS 456
Score = 34.7 bits (78), Expect = 0.36
Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Frame = +3
Query: 6 VTAHVAKLQLGGSNAFYGH-PVRIEFSTRKSLDIKHESDTGRDYT 137
V A AK+ L G N + +RI+FS SL++K+ +D RD+T
Sbjct: 201 VNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFT 245
>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1)
Length = 523
Score = 139 bits (349), Expect = 1e-32
Identities = 68/130 (52%), Positives = 87/130 (66%)
Frame = +3
Query: 495 NSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLN 674
NSV++V NLN D I P LFILFGVYGDV RVKI++NKK AL+Q D A A+ +L+
Sbjct: 328 NSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQIAMNHLS 387
Query: 675 NVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGT 854
LYGK +R SKH ++ +P+ E Q L KD+SNS LHRFK+ S+ QNI+PP
Sbjct: 388 GQRLYGKVLRATLSKHQAVQLPR-EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSA 446
Query: 855 VLHLAGLPDS 884
LHL+ +P S
Sbjct: 447 TLHLSNIPPS 456
Score = 34.7 bits (78), Expect = 0.36
Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Frame = +3
Query: 6 VTAHVAKLQLGGSNAFYGH-PVRIEFSTRKSLDIKHESDTGRDYT 137
V A AK+ L G N + +RI+FS SL++K+ +D RD+T
Sbjct: 201 VNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFT 245
>sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 527
Score = 108 bits (270), Expect = 2e-23
Identities = 59/133 (44%), Positives = 80/133 (60%)
Frame = +3
Query: 486 GNSNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVT 665
G NSV++V+NLN +R+ P +LFILFGVYGDVQRVKIL+NKK AL+Q DG A +
Sbjct: 331 GAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQ--LG 388
Query: 666 NLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYP 845
+ + + +++ S E Q L KDY +S L RFK+ S+ QNI+P
Sbjct: 389 EPPERAQAAREVSAHYTVQASECAAAREGQEDQGLTKDYGSSPL-RFKKPGSKNFQNIFP 447
Query: 846 PGTVLHLAGLPDS 884
P LHL+ +P S
Sbjct: 448 PSATLHLSNIPPS 460
Score = 37.0 bits (84), Expect = 0.073
Identities = 20/45 (44%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Frame = +3
Query: 6 VTAHVAKLQLGGSNAFYGH-PVRIEFSTRKSLDIKHESDTGRDYT 137
V+A AKL L G N + +RI+FS SL++K+ +D RDYT
Sbjct: 231 VSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYT 275
>sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprotein L-like
Length = 591
Score = 80.5 bits (197), Expect = 6e-15
Identities = 47/130 (36%), Positives = 75/130 (57%), Gaps = 1/130 (0%)
Frame = +3
Query: 492 SNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNL 671
S SVV+V+ L++ ++N +F LF +YG++++VK + TAL++ D RAVT+L
Sbjct: 382 SGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHL 441
Query: 672 NNVSLYGKPMRVNFSK-HTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPP 848
NNV L+GK + V SK H+ + E ++ KD++ S+ +RF A + I PP
Sbjct: 442 NNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPP 501
Query: 849 GTVLHLAGLP 878
VLH +P
Sbjct: 502 SCVLHYYNVP 511
>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal
RNA-regulating factor) (BLOCK24 protein)
Length = 542
Score = 80.5 bits (197), Expect = 6e-15
Identities = 47/130 (36%), Positives = 75/130 (57%), Gaps = 1/130 (0%)
Frame = +3
Query: 492 SNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNL 671
S SVV+V+ L++ ++N +F LF +YG++++VK + TAL++ D RAVT+L
Sbjct: 333 SGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHL 392
Query: 672 NNVSLYGKPMRVNFSK-HTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPP 848
NNV L+GK + V SK H+ + E ++ KD++ S+ +RF A + I PP
Sbjct: 393 NNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPP 452
Query: 849 GTVLHLAGLP 878
VLH +P
Sbjct: 453 SCVLHYYNVP 462
>sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 555
Score = 75.1 bits (183), Expect = 2e-13
Identities = 45/129 (34%), Positives = 70/129 (54%), Gaps = 3/129 (2%)
Frame = +3
Query: 501 VVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNV 680
V++V L++ ++N D +F +F +YG+V++VK + +K A+++ DG RA+T+LNN
Sbjct: 349 VLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNN 408
Query: 681 SLYGKPMRVNFSKHTSISMPKPE---EQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPG 851
++G+ M V SK +I MP E S KD+S SR +RF I P
Sbjct: 409 FMFGQKMNVCVSKQPAI-MPGQSYGLEDGSCSY-KDFSESRNNRFSTPEQAAKNRIQHPS 466
Query: 852 TVLHLAGLP 878
VLH P
Sbjct: 467 NVLHFFNAP 475
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,275,244
Number of Sequences: 369166
Number of extensions: 1841737
Number of successful extensions: 4187
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3952
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4169
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8838279920
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)