Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_F24
(830 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9ET22|DPP2_MOUSE Dipeptidyl-peptidase II precursor (DPP... 229 7e-60
sp|Q9EPB1|DPP2_RAT Dipeptidyl-peptidase II precursor (DPP I... 223 4e-58
sp|Q9UHL4|DPP2_HUMAN Dipeptidyl-peptidase II precursor (DPP... 218 1e-56
sp|Q5RBU7|PCP_PONPY Lysosomal Pro-X carboxypeptidase precur... 147 3e-35
sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase precur... 147 4e-35
sp|Q7TMR0|PCP_MOUSE Lysosomal Pro-X carboxypeptidase precur... 142 1e-33
sp|P34676|YO26_CAEEL Putative serine protease Z688.6 precursor 123 5e-28
sp|P34610|PCP1_CAEEL Putative serine protease pcp-1 precursor 105 1e-22
sp|Q9NQE7|TSSP_HUMAN Thymus-specific serine protease precursor 58 4e-08
sp|Q9QXE5|TSSP_MOUSE Thymus-specific serine protease precursor 57 6e-08
>sp|Q9ET22|DPP2_MOUSE Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl
aminopeptidase II) (Quiescent cell proline dipeptidase)
(Dipeptidyl peptidase 7)
Length = 506
Score = 229 bits (584), Expect = 7e-60
Identities = 118/256 (46%), Positives = 166/256 (64%)
Frame = -2
Query: 829 FGQMRYLATQGQQGFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATNFM 650
F Q++ L QG + IS+ TC+ L+S D+ + RN F +LAMMDYPY T+F+
Sbjct: 234 FQQIKDLFLQG--AYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTDFL 291
Query: 649 GNLPAHPVRVACQNILANKDNSIVALREAGAVYYNTSQTSTCFSPFDLYIECSDITGCGL 470
G LPA+PV+V CQ +L N+ I+ LR + YN+S T C+ + LY C+D TGCG
Sbjct: 292 GPLPANPVKVGCQRLL-NEGQRIMGLRALAGLVYNSSGTEPCYDIYRLYQSCADPTGCGT 350
Query: 469 GPDSLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLE 290
G D+ AWD+QACTE+ L DSN + DMFP++P + + ++C+ + V + L+
Sbjct: 351 GSDARAWDYQACTEINLTFDSNNVT-DMFPEIPFSEELRQQYCLDTWGVWPRQDWLQTSF 409
Query: 289 WGDYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPS 110
WG ++ A+NIIFSNGDLDPW+ GGI N L +S +A+ I+GGAHHLDLR+SN DPPS
Sbjct: 410 WGGDLKAASNIIFSNGDLDPWAGGGIQSN--LSTSVIAVTIQGGAHHLDLRASNSEDPPS 467
Query: 109 VQQARQSEEFYIRKWL 62
V + R+ E IR+W+
Sbjct: 468 VVEVRKLESTLIREWV 483
>sp|Q9EPB1|DPP2_RAT Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl
aminopeptidase II) (Quiescent cell proline dipeptidase)
(Dipeptidyl peptidase 7)
Length = 500
Score = 223 bits (569), Expect = 4e-58
Identities = 115/256 (44%), Positives = 165/256 (64%)
Frame = -2
Query: 829 FGQMRYLATQGQQGFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATNFM 650
F Q++ L QG + IS+ TC+ L+S D+ + RN F +LAMMDYPY TNF+
Sbjct: 234 FQQIKDLFLQG--AYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTNFL 291
Query: 649 GNLPAHPVRVACQNILANKDNSIVALREAGAVYYNTSQTSTCFSPFDLYIECSDITGCGL 470
G LPA+PV+V C+ +L ++ I+ LR + YN+S CF + +Y C+D TGCG
Sbjct: 292 GPLPANPVKVGCERLL-SEGQRIMGLRALAGLVYNSSGMEPCFDIYQMYQSCADPTGCGT 350
Query: 469 GPDSLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLE 290
G ++ AWD+QACTE+ L DSN + DMFP++P + + ++C+ + V + L+
Sbjct: 351 GSNARAWDYQACTEINLTFDSNNVT-DMFPEIPFSDELRQQYCLDTWGVWPRPDWLQTSF 409
Query: 289 WGDYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPS 110
WG ++ A+NIIFSNGDLDPW+ GGI N L +S +A+ I+GGAHHLDLR+SN DPPS
Sbjct: 410 WGGDLKAASNIIFSNGDLDPWAGGGIQRN--LSTSIIAVTIQGGAHHLDLRASNSEDPPS 467
Query: 109 VQQARQSEEFYIRKWL 62
V + R+ E IR+W+
Sbjct: 468 VVEVRKLEATLIREWV 483
>sp|Q9UHL4|DPP2_HUMAN Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl
aminopeptidase II) (Quiescent cell proline dipeptidase)
(Dipeptidyl peptidase 7)
Length = 492
Score = 218 bits (556), Expect = 1e-56
Identities = 115/256 (44%), Positives = 159/256 (62%)
Frame = -2
Query: 829 FGQMRYLATQGQQGFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATNFM 650
F Q++ L QG + + TC+PL+ D+ + RN F +LAMMDYPY T+F+
Sbjct: 224 FRQIKDLFLQG--AYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFL 281
Query: 649 GNLPAHPVRVACQNILANKDNSIVALREAGAVYYNTSQTSTCFSPFDLYIECSDITGCGL 470
G LPA+PV+V C +L+ I LR + YN S + C+ + LY C+D TGCG
Sbjct: 282 GPLPANPVKVGCDRLLSEAQR-ITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGT 340
Query: 469 GPDSLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLE 290
GPD+ AWD+QACTE+ L SN + DMFPDLP T + ++C+ + V + L
Sbjct: 341 GPDARAWDYQACTEINLTFASNNVT-DMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSF 399
Query: 289 WGDYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPS 110
WG +R A+NIIFSNG+LDPW+ GGI N L +S +A+ I+GGAHHLDLR+S+P DP S
Sbjct: 400 WGGDLRAASNIIFSNGNLDPWAGGGIRRN--LSASVIAVTIQGGAHHLDLRASHPEDPAS 457
Query: 109 VQQARQSEEFYIRKWL 62
V +AR+ E I +W+
Sbjct: 458 VVEARKLEATIIGEWV 473
>sp|Q5RBU7|PCP_PONPY Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase)
(PRCP) (Proline carboxypeptidase)
Length = 496
Score = 147 bits (372), Expect = 3e-35
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 3/248 (1%)
Frame = -2
Query: 790 GFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATNFMGNLPAHPVRVACQ 611
G Q ++ L C PLTS D+ + W+ +V LAM+DYPYA+NF+ LPA P++V CQ
Sbjct: 253 GLQWLTGALHLCSPLTS-QDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQ 311
Query: 610 NIL-ANKDNSIVA--LREAGAVYYNTSQTSTCFSPFDLYIECSDITGCGLGPDSLAWDFQ 440
+ N +S++ + +A VYYN S C + S+ LG +L W +Q
Sbjct: 312 YLKNPNVSDSLLLQNIFQALNVYYNYSGQVKC-------LNISETATSSLG--TLGWSYQ 362
Query: 439 ACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGDYVRTATN 260
ACTE+ + +N DMF +++ C +++ V + + + G + + TN
Sbjct: 363 ACTEVVMPFCTNGVD-DMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTN 421
Query: 259 IIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQQARQSEEF 80
I+FSNG+LDPWS GG+T++ + + VA+ I GAHHLDLR+ N DP SV AR E
Sbjct: 422 IVFSNGELDPWSGGGVTKD--ITDTLVAVTISEGAHHLDLRTKNALDPTSVLLARSLEVR 479
Query: 79 YIRKWLNE 56
+++ W+ +
Sbjct: 480 HMKNWIRD 487
>sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase)
(PRCP) (Proline carboxypeptidase) (Angiotensinase C)
(Lysosomal carboxypeptidase C)
Length = 496
Score = 147 bits (371), Expect = 4e-35
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 3/248 (1%)
Frame = -2
Query: 790 GFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATNFMGNLPAHPVRVACQ 611
G Q ++ L C PLTS D+ + W+ +V LAM+DYPYA+NF+ LPA P++V CQ
Sbjct: 253 GLQWLTGALHLCSPLTS-QDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQ 311
Query: 610 NIL-ANKDNSIVA--LREAGAVYYNTSQTSTCFSPFDLYIECSDITGCGLGPDSLAWDFQ 440
+ N +S++ + +A VYYN S C + S+ LG +L W +Q
Sbjct: 312 YLKNPNVSDSLLLQNIFQALNVYYNYSGQVKC-------LNISETATSSLG--TLGWSYQ 362
Query: 439 ACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGDYVRTATN 260
ACTE+ + +N DMF +++ C +++ V + + + G + + TN
Sbjct: 363 ACTEVVMPFCTNGVD-DMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTN 421
Query: 259 IIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQQARQSEEF 80
I+FSNG+LDPWS GG+T++ + + VA+ I GAHHLDLR+ N DP SV AR E
Sbjct: 422 IVFSNGELDPWSGGGVTKD--ITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVR 479
Query: 79 YIRKWLNE 56
+++ W+ +
Sbjct: 480 HMKNWIRD 487
>sp|Q7TMR0|PCP_MOUSE Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase)
(PRCP) (Proline carboxypeptidase)
Length = 491
Score = 142 bits (358), Expect = 1e-33
Identities = 89/246 (36%), Positives = 131/246 (53%), Gaps = 3/246 (1%)
Frame = -2
Query: 790 GFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATNFMGNLPAHPVRVACQ 611
G Q ++ L C PLTS + W+ +V LAM++YPYA NF+ LPA P++ CQ
Sbjct: 251 GLQSLTNILHLCSPLTS-EKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQ 309
Query: 610 NILANKDNSIVALR---EAGAVYYNTSQTSTCFSPFDLYIECSDITGCGLGPDSLAWDFQ 440
+ + V L+ +A +VYYN S + C + S T LG S+ W FQ
Sbjct: 310 YLKNPNVSDTVLLQNIFQALSVYYNYSGQAAC-------LNISQTTTSSLG--SMGWSFQ 360
Query: 439 ACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGDYVRTATN 260
ACTEM + +N DMF ++ C ++ V + + + G + + +N
Sbjct: 361 ACTEMVMPFCTNGID-DMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSN 419
Query: 259 IIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQQARQSEEF 80
IIFSNG+LDPWS GG+T + + + VA+ I GAHHLDLR+ N DP SV +R E
Sbjct: 420 IIFSNGELDPWSGGGVTRD--ITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVK 477
Query: 79 YIRKWL 62
+++KW+
Sbjct: 478 HMKKWI 483
>sp|P34676|YO26_CAEEL Putative serine protease Z688.6 precursor
Length = 507
Score = 123 bits (309), Expect = 5e-28
Identities = 83/263 (31%), Positives = 132/263 (50%), Gaps = 15/263 (5%)
Frame = -2
Query: 799 GQQGFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATNFMGNLPAHPVRV 620
G+Q ++ K L L + D+ + +++R +AM++YPY T+F+ +LPA PV+
Sbjct: 246 GRQYLNVLYK-LDPKSKLENKDDIGFLKQYIRESMEAMAMVNYPYPTSFLSSLPAWPVKE 304
Query: 619 ACQNILA---NKDNSIVALREAGAVYYN-TSQTSTCFSPFDLYIECSDITGC----GLGP 464
AC++ ++ S L + +YYN T ST C++ C G
Sbjct: 305 ACKSASQPGKTQEESAEQLYKIVNLYYNYTGDKST---------HCANAAKCDSAYGSLG 355
Query: 463 DSLAWDFQACTEMKLYDDSNATSGDMF-PDLPLTRQQVDKHCIKKFE-VDRADNQLKYLE 290
D L W FQ CTEM + + D F D P T ++ + C++ F + L+ L
Sbjct: 356 DPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLA 415
Query: 289 WG-----DYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNP 125
G + +A+NI+FSNG LDPWS GG + + S +++ +K GAHH DLR ++P
Sbjct: 416 GGLAFGATSLPSASNIVFSNGYLDPWSGGGYDHSDKVQGSVISVILKQGAHHYDLRGAHP 475
Query: 124 ADPPSVQQARQSEEFYIRKWLNE 56
D V++ R E I+KW+ E
Sbjct: 476 QDTEEVKKVRAMETQAIKKWIKE 498
>sp|P34610|PCP1_CAEEL Putative serine protease pcp-1 precursor
Length = 565
Score = 105 bits (263), Expect = 1e-22
Identities = 77/233 (33%), Positives = 114/233 (48%), Gaps = 13/233 (5%)
Frame = -2
Query: 712 WLRNGFVMLAMMDYPYATNFMGNLPAHPVRVACQNILAN----KDNSIV-ALREAGAVYY 548
+LR +AM+DYPY T F+ LPA PV VAC + AN D +V A+ A +YY
Sbjct: 281 YLREAIEYMAMVDYPYPTGFLEPLPAWPVTVACGYMNANGTSFSDKDLVKAVANAANIYY 340
Query: 547 NTSQTSTCFSPFDLYIECSDITGCGLGPDSLAWDFQACTEMKLYDDSNATSGDMF----- 383
N ++ D I C D GLG D L W +Q C+E+ + ++ S D+F
Sbjct: 341 NYNRDPNFTYCIDFSI-CGDQGTGGLGGDELGWPWQECSEIIMAMCASGGSNDVFWNECG 399
Query: 382 PDLPLTRQQVDKHCIKKFEVDRADNQLKYLE--WGDYVRTATNIIFSNGDLDPWSLGGIT 209
D+ T QQ K + + ++ +G + ++N+I + G LDPWS GG
Sbjct: 400 KDIYQTLQQGCVSIFKSMGWTPKNWNIDAVKTLYGYDLSGSSNLILTQGHLDPWSGGGYK 459
Query: 208 ENASLPSSSV-ALWIKGGAHHLDLRSSNPADPPSVQQARQSEEFYIRKWLNEN 53
+ + + + L I G AHHLDLR N DP +V AR ++ W++ N
Sbjct: 460 VDQNNAARGIYVLEIPGSAHHLDLRQPNTCDPNTVTNARFQIIQILKCWVDPN 512
>sp|Q9NQE7|TSSP_HUMAN Thymus-specific serine protease precursor
Length = 514
Score = 57.8 bits (138), Expect = 4e-08
Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%)
Frame = -2
Query: 451 WDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLE----WG 284
W +Q CTE Y F LP Q+D C + F + + +G
Sbjct: 373 WLYQTCTEFGFYVTCENPRCP-FSQLPALPSQLDL-CEQVFGLSALSVAQAVAQTNSYYG 430
Query: 283 DYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQ 104
A ++F NGD DPW + +T+ +L SS L I+ G+H LD+ P+D PS++
Sbjct: 431 GQTPGANKVLFVNGDTDPWHVLSVTQ--ALGSSESTLLIRTGSHCLDMAPERPSDSPSLR 488
Query: 103 QARQSEEFYIRKWL 62
RQ+ ++ WL
Sbjct: 489 LGRQNIFQQLQTWL 502
>sp|Q9QXE5|TSSP_MOUSE Thymus-specific serine protease precursor
Length = 509
Score = 57.0 bits (136), Expect = 6e-08
Identities = 46/176 (26%), Positives = 70/176 (39%), Gaps = 4/176 (2%)
Frame = -2
Query: 571 REAGAVYYNTSQTSTCFSPFDLYIECSDITGCGLGPDSLAWDFQACTEMKLYDDSNATSG 392
R V + Q FS + + S+ G W +Q CTE Y
Sbjct: 332 RAVQIVLRSMGQKCLSFSRAETVAQLSNTEPQVSGVGDRQWLYQTCTEFGFYVTCEGLQC 391
Query: 391 DMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGDYVRT----ATNIIFSNGDLDPWS 224
F LP Q++ C + F + A + Y AT ++F NGD DPW
Sbjct: 392 P-FSQLPALPFQLEL-CEQVFGLSPASVAQAVAQTNSYYGGQSPGATQVLFVNGDTDPWH 449
Query: 223 LGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQQARQSEEFYIRKWLNE 56
+ +T++ L S AL I +H D+ P+D PS++ RQ ++ WL +
Sbjct: 450 VLSVTQDLGL--SEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKISQQLQDWLKD 503
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,829,159
Number of Sequences: 369166
Number of extensions: 1995436
Number of successful extensions: 4708
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4532
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4679
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8052550455
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)