Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_F20
(496 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P04069|CBPB_ASTFL Carboxypeptidase B 94 2e-19
sp|Q9JHH6|CBPB2_MOUSE Carboxypeptidase B2 precursor (Carbox... 78 1e-14
sp|Q9EQV9|CBPB2_RAT Carboxypeptidase B2 precursor (Carboxyp... 77 3e-14
sp|P09954|CBPA1_PIG Carboxypeptidase A1 precursor 75 8e-14
sp|P00731|CBPA1_RAT Carboxypeptidase A1 precursor 75 1e-13
sp|Q9UI42|CBPA4_HUMAN Carboxypeptidase A4 precursor (Carbox... 74 2e-13
sp|Q7TPZ8|CBPA1_MOUSE Carboxypeptidase A1 precursor 74 2e-13
sp|P00730|CBPA1_BOVIN Carboxypeptidase A1 precursor 73 4e-13
sp|Q6P8K8|CBPA4_MOUSE Carboxypeptidase A4 precursor 72 9e-13
sp|P19222|CBPA2_RAT Carboxypeptidase A2 precursor 72 9e-13
>sp|P04069|CBPB_ASTFL Carboxypeptidase B
Length = 303
Score = 94.0 bits (232), Expect = 2e-19
Identities = 54/146 (36%), Positives = 78/146 (53%)
Frame = +3
Query: 3 LETQQFADFVNKLGLNLKLYFSFHAYAQFWFVPFAFGHTKPSDDSELRRVANIGNRALYG 182
+E + D + + N+K+Y +FH+Y+Q W P+ F P D +L +A AL
Sbjct: 166 VEMRNVRDQILEYAANIKVYLTFHSYSQLWMYPWGFTSDLPDDWQDLDTLATNAVDALTA 225
Query: 183 VNYETFYVGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYI 362
V+ + +GS +YAAAGG+ DW K + VKYAYT+ELR TG GFL P + I
Sbjct: 226 VHGTRYEIGSSTNTIYAAAGGSDDWAKGEGGVKYAYTIELR-----DTGNYGFLLPENQI 280
Query: 363 SRSGEEVYAGLLATVQAMTN*TKSKY 440
+GEE + G V+ + N K Y
Sbjct: 281 IPTGEETFEG----VKVVANFVKDTY 302
>sp|Q9JHH6|CBPB2_MOUSE Carboxypeptidase B2 precursor (Carboxypeptidase U)
(Thrombin-activatable fibrinolysis inhibitor) (TAFI)
(Carboxypeptidase R) (CPR)
Length = 422
Score = 78.2 bits (191), Expect = 1e-14
Identities = 49/131 (37%), Positives = 70/131 (53%), Gaps = 1/131 (0%)
Frame = +3
Query: 6 ETQQFADFVNKLGLNLKLYFSFHAYAQFWFVPFAFGHTKPSDDSELRRVANIGNRALYGV 185
E + ADF+ + ++K Y S H+Y+Q P+++ +K D EL VA+ RA+ +
Sbjct: 287 EVKAVADFLRRNIDHIKAYISMHSYSQQILFPYSYNRSKSKDHEELSLVASEAVRAIESI 346
Query: 186 NYETFYV-GSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYI 362
N T Y GS E LY A GG+ DWI +KY++T+ELR TG GFL P YI
Sbjct: 347 NKNTRYTHGSGSESLYLAPGGSDDWI-YDLGIKYSFTIELR-----DTGRYGFLLPERYI 400
Query: 363 SRSGEEVYAGL 395
+ E A +
Sbjct: 401 KPTCAEALAAI 411
>sp|Q9EQV9|CBPB2_RAT Carboxypeptidase B2 precursor (Carboxypeptidase U)
(Thrombin-activatable fibrinolysis inhibitor) (TAFI)
(Carboxypeptidase R) (CPR)
Length = 422
Score = 76.6 bits (187), Expect = 3e-14
Identities = 48/131 (36%), Positives = 70/131 (53%), Gaps = 1/131 (0%)
Frame = +3
Query: 6 ETQQFADFVNKLGLNLKLYFSFHAYAQFWFVPFAFGHTKPSDDSELRRVANIGNRALYGV 185
E + ADF+ + ++K Y S H+Y+Q P+++ +K D EL VA+ RA+ +
Sbjct: 287 EVKAVADFLRRNINHIKAYISMHSYSQQILFPYSYNRSKSKDHEELSLVASEAVRAIESI 346
Query: 186 NYETFYV-GSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYI 362
N T Y GS E LY A GG+ DWI +KY++T+ELR TG GFL P +I
Sbjct: 347 NKNTRYTHGSGSESLYLAPGGSDDWI-YDLGIKYSFTIELR-----DTGRYGFLLPERFI 400
Query: 363 SRSGEEVYAGL 395
+ E A +
Sbjct: 401 KPTCAEALAAV 411
>sp|P09954|CBPA1_PIG Carboxypeptidase A1 precursor
Length = 419
Score = 75.1 bits (183), Expect = 8e-14
Identities = 45/140 (32%), Positives = 70/140 (50%)
Frame = +3
Query: 3 LETQQFADFVNKLGLNLKLYFSFHAYAQFWFVPFAFGHTKPSDDSELRRVANIGNRALYG 182
+E + DFVN G N+K + S H+Y+Q P+ + P+D EL +++ AL
Sbjct: 284 VEVKSIVDFVNDHG-NIKAFISIHSYSQLLLYPYGYKTEAPADKDELDQISKSAVAALTS 342
Query: 183 VNYETFYVGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYI 362
+ F GS +Y A+GG DW + +KY+++ ELR TG GFL P S I
Sbjct: 343 LYGTKFQYGSIITTIYQASGGTIDWTYNQ-GIKYSFSFELR-----DTGRYGFLLPASQI 396
Query: 363 SRSGEEVYAGLLATVQAMTN 422
+ +E + LL ++ N
Sbjct: 397 IPTAQETWLALLTIMEHTLN 416
>sp|P00731|CBPA1_RAT Carboxypeptidase A1 precursor
Length = 419
Score = 74.7 bits (182), Expect = 1e-13
Identities = 45/132 (34%), Positives = 68/132 (51%)
Frame = +3
Query: 3 LETQQFADFVNKLGLNLKLYFSFHAYAQFWFVPFAFGHTKPSDDSELRRVANIGNRALYG 182
+E + DFV G N+K + S H+Y+Q P+ + D +EL ++A AL
Sbjct: 284 VEVKSIVDFVTSHG-NIKAFISIHSYSQLLLYPYGYTSEPAPDQAELDQLAKSAVTALTS 342
Query: 183 VNYETFYVGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYI 362
++ F GS + +Y A+G DW ++ +KY++T ELR TGL GFL P S I
Sbjct: 343 LHGTKFKYGSIIDTIYQASGSTIDWTYSQ-GIKYSFTFELR-----DTGLRGFLLPASQI 396
Query: 363 SRSGEEVYAGLL 398
+ EE + LL
Sbjct: 397 IPTAEETWLALL 408
>sp|Q9UI42|CBPA4_HUMAN Carboxypeptidase A4 precursor (Carboxypeptidase A3)
Length = 421
Score = 73.9 bits (180), Expect = 2e-13
Identities = 44/131 (33%), Positives = 66/131 (50%)
Frame = +3
Query: 3 LETQQFADFVNKLGLNLKLYFSFHAYAQFWFVPFAFGHTKPSDDSELRRVANIGNRALYG 182
+E + DF+ K G N K + H+Y+Q P+ + K D EL +VA + +AL
Sbjct: 286 VEVKSVVDFIQKHG-NFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALAS 344
Query: 183 VNYETFYVGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYI 362
V+ + VG +Y A+G + DW +K+A+T ELR TG GFL P + I
Sbjct: 345 VSGTEYQVGPTCTTVYPASGSSIDWAYDNG-IKFAFTFELR-----DTGTYGFLLPANQI 398
Query: 363 SRSGEEVYAGL 395
+ EE + GL
Sbjct: 399 IPTAEETWLGL 409
>sp|Q7TPZ8|CBPA1_MOUSE Carboxypeptidase A1 precursor
Length = 419
Score = 73.9 bits (180), Expect = 2e-13
Identities = 45/132 (34%), Positives = 67/132 (50%)
Frame = +3
Query: 3 LETQQFADFVNKLGLNLKLYFSFHAYAQFWFVPFAFGHTKPSDDSELRRVANIGNRALYG 182
+E + DFV G N+K + S H+Y+Q P+ + D EL ++A AL
Sbjct: 284 VEVKSIVDFVTSHG-NIKAFISIHSYSQLLLYPYGYTSEPAPDKEELDQLAKSAVTALTS 342
Query: 183 VNYETFYVGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYI 362
++ F GS + +Y A+G DW ++ +KY++T ELR TGL GFL P S I
Sbjct: 343 LHGTKFKYGSIIDTIYQASGSTIDWTYSQ-GIKYSFTFELR-----DTGLRGFLLPASQI 396
Query: 363 SRSGEEVYAGLL 398
+ EE + LL
Sbjct: 397 IPTAEETWLALL 408
>sp|P00730|CBPA1_BOVIN Carboxypeptidase A1 precursor
Length = 419
Score = 72.8 bits (177), Expect = 4e-13
Identities = 45/140 (32%), Positives = 69/140 (49%)
Frame = +3
Query: 3 LETQQFADFVNKLGLNLKLYFSFHAYAQFWFVPFAFGHTKPSDDSELRRVANIGNRALYG 182
+E + DFV G N K + S H+Y+Q P+ + D +EL +VA AL
Sbjct: 284 VEVKSIVDFVKDHG-NFKAFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVEALKS 342
Query: 183 VNYETFYVGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYI 362
+ ++ GS +Y A+GG+ DW +KY++T ELR TG GFL P S I
Sbjct: 343 LYGTSYKYGSIITTIYQASGGSIDW-SYNQGIKYSFTFELR-----DTGRYGFLLPASQI 396
Query: 363 SRSGEEVYAGLLATVQAMTN 422
+ +E + G+L ++ N
Sbjct: 397 IPTAQETWLGVLTIMEHTLN 416
>sp|Q6P8K8|CBPA4_MOUSE Carboxypeptidase A4 precursor
Length = 420
Score = 71.6 bits (174), Expect = 9e-13
Identities = 45/131 (34%), Positives = 64/131 (48%)
Frame = +3
Query: 3 LETQQFADFVNKLGLNLKLYFSFHAYAQFWFVPFAFGHTKPSDDSELRRVANIGNRALYG 182
+E + DF+ K G N K + H+Y+Q P+ + K D EL VA +AL
Sbjct: 285 VEVKSVVDFIQKHG-NFKCFIDLHSYSQLLMYPYGYTVKKAPDAEELDDVARNAAQALAS 343
Query: 183 VNYETFYVGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYI 362
++ + VG +Y A+G + DW +KYA+T ELR TG GFL P S I
Sbjct: 344 LSGTKYRVGPTCTTVYPASGSSVDWAYDNG-IKYAFTFELR-----DTGYYGFLLPASQI 397
Query: 363 SRSGEEVYAGL 395
+ EE + GL
Sbjct: 398 IPTAEETWLGL 408
>sp|P19222|CBPA2_RAT Carboxypeptidase A2 precursor
Length = 417
Score = 71.6 bits (174), Expect = 9e-13
Identities = 42/131 (32%), Positives = 68/131 (51%)
Frame = +3
Query: 3 LETQQFADFVNKLGLNLKLYFSFHAYAQFWFVPFAFGHTKPSDDSELRRVANIGNRALYG 182
+E + DF+ G +K + + H+Y+Q P+ + TKP D +EL VA +AL
Sbjct: 282 VEVKSIVDFIKSHG-KVKAFITLHSYSQLLMFPYGYKCTKPDDFNELDEVAQKAAQALKR 340
Query: 183 VNYETFYVGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYI 362
++ ++ VG ++Y A+GG+ DW +KY++ ELR + Y GFL P I
Sbjct: 341 LHGTSYKVGPICSVIYQASGGSIDW-AYDLGIKYSFAFELRDTAFY-----GFLLPAKQI 394
Query: 363 SRSGEEVYAGL 395
+ EE + GL
Sbjct: 395 LPTAEETWLGL 405
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,010,242
Number of Sequences: 369166
Number of extensions: 874842
Number of successful extensions: 2250
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2193
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2231
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3069744620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)