Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_013_C04 (768 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q96B97|SH3K1_HUMAN SH3-domain kinase binding protein 1 (... 33 0.65 sp|Q07157|ZO1_HUMAN Tight junction protein ZO-1 (Zonula occ... 33 1.1 sp|P08297|NO75_SOYBN Early nodulin 75 precursor (N-75) (NGM... 32 1.9 sp|P39447|ZO1_MOUSE Tight junction protein ZO-1 (Zonula occ... 32 1.9 sp|Q64028|PHC1_MOUSE Polyhomeotic-like protein 1 (Early dev... 32 2.5 sp|Q8R550|SH3K1_MOUSE SH3-domain kinase binding protein 1 (... 32 2.5 sp|Q925Q9|SH3K1_RAT SH3-domain kinase binding protein 1 (SH... 32 2.5 sp|P25558|BUD3_YEAST Bud site selection protein BUD3 31 3.2 sp|Q9PGD4|PBPA_XYLFA Penicillin-binding protein 1A (PBP-1a)... 30 5.5 sp|P16329|NO75_PEA Early nodulin 75 protein (N-75) (NGM-75) 30 7.2
>sp|Q96B97|SH3K1_HUMAN SH3-domain kinase binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase binding protein 1) (HSB-1) (CD2 binding protein 3) (CD2BP3) Length = 665 Score = 33.5 bits (75), Expect = 0.65 Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 3/77 (3%) Frame = +3 Query: 405 PLMKVNQQSEPEIIKKPENNAHL---KQTMTAYKPKQAQPTNRIPKTVYKAKNVSRPPQT 575 P M N+ E E +PE L K ++ A PK+ +P PKT ++SRP Sbjct: 369 PEMLPNRTEEKE---RPEREPKLDLQKPSVPAIPPKKPRP----PKT----NSLSRPG-A 416 Query: 576 LPKKEPTRPVGPACLTK 626 LP + P RPVGP T+ Sbjct: 417 LPPRRPERPVGPLTHTR 433
>sp|Q07157|ZO1_HUMAN Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1) Length = 1748 Score = 32.7 bits (73), Expect = 1.1 Identities = 14/42 (33%), Positives = 27/42 (64%) Frame = +3 Query: 447 KKPENNAHLKQTMTAYKPKQAQPTNRIPKTVYKAKNVSRPPQ 572 + P+ N +L + TA+KP + T PKT+ K+ ++++PP+ Sbjct: 1544 ESPKFNHNLLPSETAHKPDLSSKTPTSPKTLVKSHSLAQPPE 1585
>sp|P08297|NO75_SOYBN Early nodulin 75 precursor (N-75) (NGM-75) Length = 309 Score = 32.0 bits (71), Expect = 1.9 Identities = 20/76 (26%), Positives = 29/76 (38%) Frame = +3 Query: 405 PLMKVNQQSEPEIIKKPENNAHLKQTMTAYKPKQAQPTNRIPKTVYKAKNVSRPPQTLPK 584 P K + P PE ++ Y+P Q +P + P Y+ + PP+ P Sbjct: 184 PHEKPPEHQPPHEKPPPEYQPPHEKPPPEYQPPQEKPPHEKPPPEYQPPHEKPPPEHQPP 243 Query: 585 KEPTRPVGPACLTKKP 632 E PV P K P Sbjct: 244 HEKPPPVYPPPYEKPP 259
>sp|P39447|ZO1_MOUSE Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1) Length = 1745 Score = 32.0 bits (71), Expect = 1.9 Identities = 14/42 (33%), Positives = 26/42 (61%) Frame = +3 Query: 447 KKPENNAHLKQTMTAYKPKQAQPTNRIPKTVYKAKNVSRPPQ 572 + P+ N +L + T +KP+ + T PKT+ KA + ++PP+ Sbjct: 1541 ESPKFNHNLLPSETVHKPELSSKTPTSPKTLMKAHSSTQPPE 1582
>sp|Q64028|PHC1_MOUSE Polyhomeotic-like protein 1 (Early development regulator protein 1) (MPH1) (RAE-28) Length = 1012 Score = 31.6 bits (70), Expect = 2.5 Identities = 23/114 (20%), Positives = 44/114 (38%), Gaps = 8/114 (7%) Frame = +3 Query: 315 QREIVLSHMKNLNELQXXXXXXXXXXXXXXPLMKVNQQSEPEIIKKPENNAHLKQTMTAY 494 Q++I + H + Q + QQ + + ++ + T+TA Sbjct: 396 QQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQQQQQQQQQQGTTLTAP 455 Query: 495 KPKQAQPTNRIP--------KTVYKAKNVSRPPQTLPKKEPTRPVGPACLTKKP 632 +P Q PT ++P +T+ + P TLP + ++P P + KP Sbjct: 456 QPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLTLPPEPTSKP--PIPIQSKP 507
>sp|Q8R550|SH3K1_MOUSE SH3-domain kinase binding protein 1 (SH3 containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk) Length = 709 Score = 31.6 bits (70), Expect = 2.5 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 3/63 (4%) Frame = +3 Query: 447 KKPENNAHL---KQTMTAYKPKQAQPTNRIPKTVYKAKNVSRPPQTLPKKEPTRPVGPAC 617 ++PE L K ++ A PK+ +P PKT N P LP + P RPVGP Sbjct: 424 ERPEREPKLDLQKPSVPAIPPKKPRP----PKT-----NSLNRPGALPPRRPERPVGPLT 474 Query: 618 LTK 626 T+ Sbjct: 475 HTR 477
>sp|Q925Q9|SH3K1_RAT SH3-domain kinase binding protein 1 (SH3 containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk) Length = 709 Score = 31.6 bits (70), Expect = 2.5 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 3/63 (4%) Frame = +3 Query: 447 KKPENNAHL---KQTMTAYKPKQAQPTNRIPKTVYKAKNVSRPPQTLPKKEPTRPVGPAC 617 ++PE L K ++ A PK+ +P PKT N P LP + P RPVGP Sbjct: 424 ERPEREPKLDLQKPSVPAIPPKKPRP----PKT-----NSLNRPGVLPPRRPERPVGPLT 474 Query: 618 LTK 626 T+ Sbjct: 475 HTR 477
>sp|P25558|BUD3_YEAST Bud site selection protein BUD3 Length = 1636 Score = 31.2 bits (69), Expect = 3.2 Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 7/87 (8%) Frame = +3 Query: 414 KVNQQSEPEIIKKPENNAHLKQTMTAYKPKQAQPTNRIPKTVYKAKNVSRP------PQT 575 K + + EI KK + NA + + KP + + + K V+ +K+ S+P P+ Sbjct: 816 KKSSKKpreIQKKTKTNASKAEHIEKKKPNKGKGFFGVLKNVFGSKSKSKPSPVQRVPKK 875 Query: 576 LPKKEPTRPV-GPACLTKKPNNVRIVI 653 + ++ P PV P KK + R V+ Sbjct: 876 ISQRHPKSPVKKPMTSEKKSSPKRAVV 902
>sp|Q9PGD4|PBPA_XYLFA Penicillin-binding protein 1A (PBP-1a) (PBP1a) [Includes: Penicillin-insensitive transglycosylase (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (DD-transpeptidase)] Length = 809 Score = 30.4 bits (67), Expect = 5.5 Identities = 10/27 (37%), Positives = 17/27 (62%) Frame = +3 Query: 549 KNVSRPPQTLPKKEPTRPVGPACLTKK 629 KN + PPQT+P +P P+ P + ++ Sbjct: 642 KNNNEPPQTIPSPDPNTPMAPRAIDER 668
>sp|P16329|NO75_PEA Early nodulin 75 protein (N-75) (NGM-75) Length = 112 Score = 30.0 bits (66), Expect = 7.2 Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 9/49 (18%) Frame = +3 Query: 492 YKPKQAQPTNRIPKTVYKAKNVSRPP---------QTLPKKEPTRPVGP 611 Y+P +P + P VYK + PP Q P +P+RP GP Sbjct: 58 YQPPHEKPPHENPPPVYKPPYENSPPPHVYHRPLFQAPPPVKPSRPFGP 106
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 57,845,852 Number of Sequences: 369166 Number of extensions: 899291 Number of successful extensions: 2701 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2556 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2685 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 7115329200 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)