Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_B19
(427 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P37167|ACTP_ACACA Actophorin 57 2e-08
sp|P18359|DEST_CHICK Destrin (Actin-depolymerizing factor) ... 55 8e-08
sp|P23528|COF1_HUMAN Cofilin-1 (Cofilin, non-muscle isoform... 53 2e-07
sp|P45592|COF1_RAT Cofilin-1 (Cofilin, non-muscle isoform) 53 2e-07
sp|Q9Y281|COF2_HUMAN Cofilin-2 (Cofilin, muscle isoform) 53 3e-07
sp|P18760|COF1_MOUSE Cofilin-1 (Cofilin, non-muscle isoform) 53 3e-07
sp|P45591|COF2_MOUSE Cofilin-2 (Cofilin, muscle isoform) 53 3e-07
sp|P10668|COF1_PIG Cofilin-1 (Cofilin, non-muscle isoform) ... 52 4e-07
sp|P21566|COF2_CHICK Cofilin-2 (Cofilin, muscle isoform) 52 4e-07
sp|P60982|DEST_PIG Destrin (Actin-depolymerizing factor) (A... 52 5e-07
>sp|P37167|ACTP_ACACA Actophorin
Length = 138
Score = 57.0 bits (136), Expect = 2e-08
Identities = 29/113 (25%), Positives = 53/113 (46%), Gaps = 8/113 (7%)
Frame = +2
Query: 5 YGLNKEKNRIIKLETGDLGTPYEKFKQHIIETYAQEGCYALYDYE--------GTLAFIS 160
+ +N ++ G YE FK + E + YA++DYE + FI
Sbjct: 28 FKMNASNTEVVVEHVGGPNATYEDFKSQLPERDCR---YAIFDYEFQVDGGQRNKITFIL 84
Query: 161 WIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEIDESVIKEKTASKV 319
W P++ I S+M+ ++K I ++VG++ +++A EI E + E+ V
Sbjct: 85 WAPDSAPIKSKMMYTSTKDSIKKKLVGIQVEVQATDAAEISEDAVSERAKKDV 137
>sp|P18359|DEST_CHICK Destrin (Actin-depolymerizing factor) (ADF)
Length = 165
Score = 54.7 bits (130), Expect = 8e-08
Identities = 36/115 (31%), Positives = 57/115 (49%), Gaps = 14/115 (12%)
Frame = +2
Query: 2 IYGLNKEKNRIIKLE-----TGDLGTPYEKFKQHIIETYAQEGC-YALYDY--------E 139
I+ L+ +K II E GD+G +H +E ++ C YALYD +
Sbjct: 37 IFCLSPDKKCIIVEEGKEILVGDVGVTVTDPFKHFVEMLPEKDCRYALYDASFETKESKK 96
Query: 140 GTLAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEIDESVIKEK 304
L F W PE + S+MI A+SK I + G+K + +AN ++++ + I EK
Sbjct: 97 EELMFFLWAPEQAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEK 151
>sp|P23528|COF1_HUMAN Cofilin-1 (Cofilin, non-muscle isoform) (18 kDa phosphoprotein)
(p18)
Length = 166
Score = 53.1 bits (126), Expect = 2e-07
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 15/116 (12%)
Frame = +2
Query: 2 IYGLNKEKNRIIKLE-----TGDLGTPYEKFKQHIIETYAQEGC-YALYD--YEGT---- 145
++ L+++K II E GD+G + ++ + C YALYD YE
Sbjct: 37 LFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKK 96
Query: 146 --LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEK 304
L FI W PE+ + S+MI A+SK I ++ G+K +++AN +E+ D + EK
Sbjct: 97 EDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEK 152
>sp|P45592|COF1_RAT Cofilin-1 (Cofilin, non-muscle isoform)
Length = 166
Score = 53.1 bits (126), Expect = 2e-07
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 15/116 (12%)
Frame = +2
Query: 2 IYGLNKEKNRIIKLE-----TGDLGTPYEKFKQHIIETYAQEGC-YALYD--YEGT---- 145
++ L+++K II E GD+G + ++ + C YALYD YE
Sbjct: 37 LFCLSEDKKNIILEEGKEILVGDVGQTVDDPYTTFVKMLPDKDCRYALYDATYETKESKK 96
Query: 146 --LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEK 304
L FI W PE+ + S+MI A+SK I ++ G+K +++AN +E+ D + EK
Sbjct: 97 EDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEK 152
>sp|Q9Y281|COF2_HUMAN Cofilin-2 (Cofilin, muscle isoform)
Length = 166
Score = 52.8 bits (125), Expect = 3e-07
Identities = 40/121 (33%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Frame = +2
Query: 2 IYGLNKEKNRIIKLET-----GDLGTPYEKFKQHIIETYAQEGC-YALYD--YEGT---- 145
++ L+ +K +II E GD+G E ++ C YALYD YE
Sbjct: 37 LFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKK 96
Query: 146 --LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEKTASK 316
L FI W PE+ + S+MI A+SK I + G+K + + N D+I D S + EK
Sbjct: 97 EDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGN 156
Query: 317 V 319
V
Sbjct: 157 V 157
>sp|P18760|COF1_MOUSE Cofilin-1 (Cofilin, non-muscle isoform)
Length = 166
Score = 52.8 bits (125), Expect = 3e-07
Identities = 37/116 (31%), Positives = 59/116 (50%), Gaps = 15/116 (12%)
Frame = +2
Query: 2 IYGLNKEKNRIIKLE-----TGDLGTPYEKFKQHIIETYAQEGC-YALYD--YEGT---- 145
++ L+++K II E GD+G + ++ + C YALYD YE
Sbjct: 37 LFCLSEDKKNIILEEGKEILVGDVGQTVDDPYTTFVKMLPDKDCRYALYDATYETKESKK 96
Query: 146 --LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEK 304
L FI W PE + S+MI A+SK I ++ G+K +++AN +E+ D + EK
Sbjct: 97 EDLVFIFWAPENAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEK 152
>sp|P45591|COF2_MOUSE Cofilin-2 (Cofilin, muscle isoform)
Length = 166
Score = 52.8 bits (125), Expect = 3e-07
Identities = 40/121 (33%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Frame = +2
Query: 2 IYGLNKEKNRIIKLET-----GDLGTPYEKFKQHIIETYAQEGC-YALYD--YEGT---- 145
++ L+ +K +II E GD+G E ++ C YALYD YE
Sbjct: 37 LFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKK 96
Query: 146 --LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEKTASK 316
L FI W PE+ + S+MI A+SK I + G+K + + N D+I D S + EK
Sbjct: 97 EDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGS 156
Query: 317 V 319
V
Sbjct: 157 V 157
>sp|P10668|COF1_PIG Cofilin-1 (Cofilin, non-muscle isoform)
sp|Q6B7M7|COF1_SHEEP Cofilin-1 (Cofilin, non-muscle isoform)
Length = 166
Score = 52.4 bits (124), Expect = 4e-07
Identities = 37/116 (31%), Positives = 59/116 (50%), Gaps = 15/116 (12%)
Frame = +2
Query: 2 IYGLNKEKNRIIKLE-----TGDLGTPYEKFKQHIIETYAQEGC-YALYD--YEGT---- 145
++ L+++K II E GD+G + ++ + C YALYD YE
Sbjct: 37 LFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKK 96
Query: 146 --LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEK 304
L FI W PE + S+MI A+SK I ++ G+K +++AN +E+ D + EK
Sbjct: 97 EDLVFIFWAPECAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEK 152
>sp|P21566|COF2_CHICK Cofilin-2 (Cofilin, muscle isoform)
Length = 166
Score = 52.4 bits (124), Expect = 4e-07
Identities = 40/121 (33%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Frame = +2
Query: 2 IYGLNKEKNRIIKLET-----GDLGTPYEKFKQHIIETYAQEGC-YALYD--YEGT---- 145
++ L+ +K +II E GD+G E ++ C YALYD YE
Sbjct: 37 LFCLSDDKKQIIVEEAKQILVGDIGDTVEDPYTAFVKLLPLNDCRYALYDATYETKESKK 96
Query: 146 --LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEKTASK 316
L FI W PE+ + S+MI A+SK I + G+K + + N D+I D S + EK
Sbjct: 97 EDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGN 156
Query: 317 V 319
V
Sbjct: 157 V 157
>sp|P60982|DEST_PIG Destrin (Actin-depolymerizing factor) (ADF)
sp|P60981|DEST_HUMAN Destrin (Actin-depolymerizing factor) (ADF)
Length = 165
Score = 52.0 bits (123), Expect = 5e-07
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 14/115 (12%)
Frame = +2
Query: 2 IYGLNKEKNRIIKLE-----TGDLGTPYEKFKQHIIETYAQEGC-YALYDY--------E 139
I+ L+ +K II E GD+G +H + ++ C YALYD +
Sbjct: 37 IFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETKESRK 96
Query: 140 GTLAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEIDESVIKEK 304
L F W PE + S+MI A+SK I + G+K + +AN ++++ + I EK
Sbjct: 97 EELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEK 151
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,524,113
Number of Sequences: 369166
Number of extensions: 678511
Number of successful extensions: 1616
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1582
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1613
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 2102781030
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)