Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_B12
(835 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99KV1|DNJBB_MOUSE DnaJ homolog subfamily B member 11 pr... 325 1e-88
sp|Q9UBS4|DNJBB_HUMAN DnaJ homolog subfamily B member 11 pr... 323 5e-88
sp|Q8MPX3|DNJ20_CAEEL DnaJ homolog dnj-20 precursor (DnaJ d... 189 8e-48
sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (DNAJ-1) 133 7e-31
sp|Q04960|DNJH_CUCSA DnaJ protein homolog (DNAJ-1) 127 3e-29
sp|O60884|DNJA2_HUMAN DnaJ homolog subfamily A member 2 (HI... 127 3e-29
sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2 126 6e-29
sp|Q9QYJ0|DNJA2_MOUSE DnaJ homolog subfamily A member 2 (mDj3) 125 1e-28
sp|O35824|DNJA2_RAT DnaJ homolog subfamily A member 2 (RDJ2) 125 1e-28
sp|Q94AW8|DNAJ3_ARATH Chaperone protein dnaJ 3 (AtJ3) (AtDjA3) 124 3e-28
>sp|Q99KV1|DNJBB_MOUSE DnaJ homolog subfamily B member 11 precursor
Length = 358
Score = 325 bits (832), Expect = 1e-88
Identities = 160/256 (62%), Positives = 194/256 (75%), Gaps = 2/256 (0%)
Frame = +3
Query: 24 DPFSSFFGDVFFDMGGSRRQKD--IPRGGDVIMDLFVSLEELYNGNFVEVVRYKSVKKSA 197
D FS FFGD F GG+ RQ+D IPRG D+I+DL V+LEE+Y GNFVEVVR K V + A
Sbjct: 104 DIFSHFFGDFGFMFGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQA 163
Query: 198 HGTRKCNCRHEMKTIQTGPGRFTMTQEQVCDECPNVRFVPEEKLLEVEIEPGMRDGQLYP 377
G RKCNCR EM+T Q GPGRF MTQE VCDECPNV+ V EE+ LEVEIEPG+RDG YP
Sbjct: 164 PGKRKCNCRQEMRTTQLGPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYP 223
Query: 378 FVAEGEPHIDGEPGDLKFRIRQSKHARFERRGDDLYTNVTISLLDALQGFTMEIKHLDGH 557
F+ EGEPH+DGEPGDL+FRI+ KH FERRGDDLYTNVT+SL++AL GF M+I HLDGH
Sbjct: 224 FIGEGEPHVDGEPGDLRFRIKVVKHRIFERRGDDLYTNVTVSLVEALVGFEMDITHLDGH 283
Query: 558 KVKITREKVTWPGATIRKSNEGMPNYENNHVKGSLYITIDVAFPKDKVYSNEEKEIXXXX 737
KV I+R+K+T PGA + K EG+PN++NN++KGSL IT DV FPK+++ + E KE
Sbjct: 284 KVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQL-TEEAKEGIKQL 342
Query: 738 XXXXXKPQEYNGLGGF 785
+ YNGL G+
Sbjct: 343 LKQGPVQKVYNGLQGY 358
>sp|Q9UBS4|DNJBB_HUMAN DnaJ homolog subfamily B member 11 precursor (ER-associated dnaJ
protein 3) (ErJ3) (ER-associated Hsp40 co-chaperone)
(hDj9) (PWP1-interacting protein 4)
Length = 358
Score = 323 bits (827), Expect = 5e-88
Identities = 159/256 (62%), Positives = 194/256 (75%), Gaps = 2/256 (0%)
Frame = +3
Query: 24 DPFSSFFGDVFFDMGGSRRQKD--IPRGGDVIMDLFVSLEELYNGNFVEVVRYKSVKKSA 197
D FS FFGD F GG+ RQ+D IPRG D+I+DL V+LEE+Y GNFVEVVR K V + A
Sbjct: 104 DIFSHFFGDFGFMFGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQA 163
Query: 198 HGTRKCNCRHEMKTIQTGPGRFTMTQEQVCDECPNVRFVPEEKLLEVEIEPGMRDGQLYP 377
G RKCNCR EM+T Q GPGRF MTQE VCDECPNV+ V EE+ LEVEIEPG+RDG YP
Sbjct: 164 PGKRKCNCRQEMRTTQLGPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYP 223
Query: 378 FVAEGEPHIDGEPGDLKFRIRQSKHARFERRGDDLYTNVTISLLDALQGFTMEIKHLDGH 557
F+ EGEPH+DGEPGDL+FRI+ KH FERRGDDLYTNVTISL+++L GF M+I HLDGH
Sbjct: 224 FIGEGEPHVDGEPGDLRFRIKVVKHPIFERRGDDLYTNVTISLVESLVGFEMDITHLDGH 283
Query: 558 KVKITREKVTWPGATIRKSNEGMPNYENNHVKGSLYITIDVAFPKDKVYSNEEKEIXXXX 737
KV I+R+K+T PGA + K EG+PN++NN++KGSL IT DV FPK+++ + E +E
Sbjct: 284 KVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQL-TEEAREGIKQL 342
Query: 738 XXXXXKPQEYNGLGGF 785
+ YNGL G+
Sbjct: 343 LKQGSVQKVYNGLQGY 358
>sp|Q8MPX3|DNJ20_CAEEL DnaJ homolog dnj-20 precursor (DnaJ domain protein 20)
Length = 249
Score = 189 bits (480), Expect = 8e-48
Identities = 90/150 (60%), Positives = 109/150 (72%)
Frame = +3
Query: 9 GGSSMDPFSSFFGDVFFDMGGSRRQKDIPRGGDVIMDLFVSLEELYNGNFVEVVRYKSVK 188
GG DPFSSFFGD F GG ++ P+G DV +DLFV+LEE+YNG+FVE+ R K+V
Sbjct: 100 GGGGHDPFSSFFGDFFGGGGGHGGEEGTPKGADVTIDLFVTLEEVYNGHFVEIKRKKAVY 159
Query: 189 KSAHGTRKCNCRHEMKTIQTGPGRFTMTQEQVCDECPNVRFVPEEKLLEVEIEPGMRDGQ 368
K GTR+CNCRHEM+T Q G GRF M Q +VCDECPNV+ V E K+LEVE+E G +G
Sbjct: 160 KQTSGTRQCNCRHEMRTEQMGQGRFQMFQVKVCDECPNVKLVQENKVLEVEVEVGADNGH 219
Query: 369 LYPFVAEGEPHIDGEPGDLKFRIRQSKHAR 458
F EGEPHI+G+PGDLKF+IR KH R
Sbjct: 220 QQIFHGEGEPHIEGDPGDLKFKIRIQKHPR 249
>sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (DNAJ-1)
Length = 397
Score = 133 bits (334), Expect = 7e-31
Identities = 91/259 (35%), Positives = 126/259 (48%), Gaps = 32/259 (12%)
Frame = +3
Query: 9 GGSSMDPFS---SFFGDVFFDMGGSRRQKDIPRGGDVIMDLFVSLEELYNGNFVEVVRYK 179
GG DPF SFFG F GGS R + RG DV+ L VSLEELYNG ++ +
Sbjct: 64 GGGDHDPFDIFQSFFGGGGFGGGGSSRGRRQRRGEDVVHPLKVSLEELYNGTSKKLSLSR 123
Query: 180 SV---------KKSAHGTRKCNCRHEMKTI---QTGPGRFTMTQEQV------------- 284
+V KS R +C+ + Q GPG Q
Sbjct: 124 NVICSKCNGKGSKSGASMRCASCQGSGMKVSIRQLGPGMIQQMQHPCNDCKGTGEMINDK 183
Query: 285 --CDECPNVRFVPEEKLLEVEIEPGMRDGQLYPFVAEGEPHIDGEPGDLKFRIRQSKHAR 458
C C + V E+K+LEV +E GM++GQ F E + D GD+ F ++Q +H +
Sbjct: 184 DRCPLCKGEKVVQEKKVLEVHVEKGMQNGQRITFPGEADEAPDTVTGDIVFVLQQKEHPK 243
Query: 459 FERRGDDLYTNVTISLLDALQGFTMEIKHLDGHK--VKITREKVTWPGATIRKSNEGMPN 632
F+R+GDDL+ T+SL +AL GF + HLDG + +K +V P ++EGMP
Sbjct: 244 FQRKGDDLFYKHTLSLTEALCGFQFVLTHLDGRQLLIKSNPGEVVKPDQFKAINDEGMPM 303
Query: 633 YENNHVKGSLYITIDVAFP 689
Y+ ++G LYI V FP
Sbjct: 304 YQRPFMRGKLYIQFLVDFP 322
>sp|Q04960|DNJH_CUCSA DnaJ protein homolog (DNAJ-1)
Length = 413
Score = 127 bits (320), Expect = 3e-29
Identities = 90/259 (34%), Positives = 130/259 (50%), Gaps = 32/259 (12%)
Frame = +3
Query: 9 GGSSMDPFS---SFFGDVFFDMGGSRRQKDIPRGGDVIMDLFVSLEELYNGNFVEVVRYK 179
GG DPF SFFG F GGS R + RG DVI L VSLE+LYNG ++ +
Sbjct: 83 GGGGHDPFDIFQSFFGGSPFGGGGSSRGRRQRRGEDVIHPLKVSLEDLYNGTSKKLSLSR 142
Query: 180 SV-------KKSAHG-TRKC-NCR---HEMKTIQTGPGRF---------------TMTQE 278
+V K S G + KC C+ ++ GP T+ +
Sbjct: 143 NVICSKCKGKGSKSGASMKCPGCQGSGMKVSIRHLGPSMIQQMQHPCNECKGTGETINDK 202
Query: 279 QVCDECPNVRFVPEEKLLEVEIEPGMRDGQLYPFVAEGEPHIDGEPGDLKFRIRQSKHAR 458
C +C + V E+K+LEV +E GM++ Q F E + D GD+ F ++Q +H +
Sbjct: 203 DRCSQCKGEKVVQEKKVLEVIVEKGMQNAQKITFPGEADEAPDTVTGDIVFVLQQKEHPK 262
Query: 459 FERRGDDLYTNVTISLLDALQGFTMEIKHLDGHK--VKITREKVTWPGATIRKSNEGMPN 632
F+R+GDDL+ T+SL+++L GF + HLDG + +K +V P ++EGMP
Sbjct: 263 FKRKGDDLFVEHTLSLVESLCGFQFILTHLDGRQLLIKSLPGEVVKPDQFKAINDEGMPM 322
Query: 633 YENNHVKGSLYITIDVAFP 689
Y+ +KG LYI V FP
Sbjct: 323 YQRPFMKGKLYIHFSVEFP 341
>sp|O60884|DNJA2_HUMAN DnaJ homolog subfamily A member 2 (HIRA interacting protein 4)
(Cell cycle progression restoration gene 3 protein)
(Dnj3)
Length = 412
Score = 127 bits (320), Expect = 3e-29
Identities = 91/260 (35%), Positives = 122/260 (46%), Gaps = 31/260 (11%)
Frame = +3
Query: 9 GGSSMDPFSSFFGDVFFDMGG--SRRQKDIPRGGDVIMDLFVSLEELYNGNFVEVVRYKS 182
GG D FS FG F G SR + RG D++ L VSLE+LYNG ++ K+
Sbjct: 81 GGGMDDIFSHIFGGGLFGFMGNQSRSRNGRRRGEDMMHPLKVSLEDLYNGKTTKLQLSKN 140
Query: 183 VKKSA--------HGTRKCN-CRHEMKTI---QTGPGRFTMTQ---------------EQ 281
V SA +KC+ CR I Q PG Q +
Sbjct: 141 VLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKD 200
Query: 282 VCDECPNVRFVPEEKLLEVEIEPGMRDGQLYPFVAEGEPHIDGEPGDLKFRIRQSKHARF 461
C +C + + E K+LEV ++ GM+ GQ F E + EPGD+ +++ +H F
Sbjct: 201 RCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVF 260
Query: 462 ERRGDDLYTNVTISLLDALQGFTMEIKHLDGHK--VKITREKVTWPGATIRKSNEGMPNY 635
+R G+DL+ I L++AL GF KHLDG + VK KV PG EGMP Y
Sbjct: 261 QRDGNDLHMTYKIGLVEALCGFQFTFKHLDGRQIVVKYPPGKVIEPGCVRVVRGEGMPQY 320
Query: 636 ENNHVKGSLYITIDVAFPKD 695
N KG LYI DV FP++
Sbjct: 321 RNPFEKGDLYIKFDVQFPEN 340
>sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2
Length = 418
Score = 126 bits (317), Expect = 6e-29
Identities = 87/263 (33%), Positives = 126/263 (47%), Gaps = 36/263 (13%)
Frame = +3
Query: 9 GGSSMDPFS---SFFGDVFFDMGGSRRQKDIPRGGDVIMDLFVSLEELYNGNFVEVVRYK 179
GG DPF SFFG F GGS R + RG DV+ L VSLE+LYNG ++ +
Sbjct: 85 GGGVHDPFDIFQSFFGGGGFGGGGSSRGRRQRRGEDVVHPLKVSLEDLYNGTSKKLSLSR 144
Query: 180 SVK------KSAHGTRKCNCRH------EMKTIQTGPGRFTMTQEQV------------- 284
+V K + NC ++ Q GPG Q
Sbjct: 145 NVLCTKCKGKGSKSGASMNCASCQGSGMKVSIRQLGPGMIQQMQHPCNECKGTGEMISDK 204
Query: 285 --CDECPNVRFVPEEKLLEVEIEPGMRDGQLYPFVAEGEPHIDGEPGDLKFRIRQSKHAR 458
C +C + V ++K+LEV +E GM++GQ F E + D GD+ F ++Q +H +
Sbjct: 205 DRCPQCKGEKVVQQKKVLEVHVEKGMQNGQKITFPGEADEAPDTVTGDIVFVLQQKEHPK 264
Query: 459 FERRGDDLYTNVTISLLDALQGFTMEIKHLDGHKVKITREKVTWPGATIRK------SNE 620
F+R+GDDL+ ++SL +AL GF + HLD ++ I PG I+ ++E
Sbjct: 265 FKRKGDDLFYEHSLSLTEALCGFQFVLTHLDNRQLLIKSN----PGEVIKPDQFKGINDE 320
Query: 621 GMPNYENNHVKGSLYITIDVAFP 689
GMP Y+ ++G LYI V FP
Sbjct: 321 GMPMYQRPFMRGKLYIHFSVDFP 343
>sp|Q9QYJ0|DNJA2_MOUSE DnaJ homolog subfamily A member 2 (mDj3)
Length = 412
Score = 125 bits (314), Expect = 1e-28
Identities = 90/260 (34%), Positives = 121/260 (46%), Gaps = 31/260 (11%)
Frame = +3
Query: 9 GGSSMDPFSSFFGDVFFDMGG--SRRQKDIPRGGDVIMDLFVSLEELYNGNFVEVVRYKS 182
GG D FS FG F G SR + RG D++ L VSLE+LYNG ++ K+
Sbjct: 81 GGGMDDIFSHIFGGGLFGFMGNQSRSRNGRRRGEDMMHPLKVSLEDLYNGKTTKLQLSKN 140
Query: 183 VKKSA--------HGTRKCN-CRHEMKTI---QTGPGRFTMTQ---------------EQ 281
V SA +KC+ CR I Q PG Q +
Sbjct: 141 VLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKD 200
Query: 282 VCDECPNVRFVPEEKLLEVEIEPGMRDGQLYPFVAEGEPHIDGEPGDLKFRIRQSKHARF 461
C +C + + E K+LEV ++ GM+ GQ F E + EPGD+ +++ +H F
Sbjct: 201 RCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVF 260
Query: 462 ERRGDDLYTNVTISLLDALQGFTMEIKHLDGHK--VKITREKVTWPGATIRKSNEGMPNY 635
+R G+DL+ I L++AL GF KHLD + VK KV PG EGMP Y
Sbjct: 261 QRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQIVVKYPPGKVIEPGCVRVVRGEGMPQY 320
Query: 636 ENNHVKGSLYITIDVAFPKD 695
N KG LYI DV FP++
Sbjct: 321 RNPFEKGDLYIKFDVQFPEN 340
>sp|O35824|DNJA2_RAT DnaJ homolog subfamily A member 2 (RDJ2)
Length = 412
Score = 125 bits (314), Expect = 1e-28
Identities = 90/260 (34%), Positives = 121/260 (46%), Gaps = 31/260 (11%)
Frame = +3
Query: 9 GGSSMDPFSSFFGDVFFDMGG--SRRQKDIPRGGDVIMDLFVSLEELYNGNFVEVVRYKS 182
GG D FS FG F G SR + RG D++ L VSLE+LYNG ++ K+
Sbjct: 81 GGGMDDIFSHIFGGGLFGFMGNQSRSRNGRRRGEDMMHPLKVSLEDLYNGKTTKLQLSKN 140
Query: 183 VKKSA--------HGTRKCN-CRHEMKTI---QTGPGRFTMTQ---------------EQ 281
V SA +KC+ CR I Q PG Q +
Sbjct: 141 VLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKD 200
Query: 282 VCDECPNVRFVPEEKLLEVEIEPGMRDGQLYPFVAEGEPHIDGEPGDLKFRIRQSKHARF 461
C +C + + E K+LEV ++ GM+ GQ F E + EPGD+ +++ +H F
Sbjct: 201 RCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLFVQEKEHEVF 260
Query: 462 ERRGDDLYTNVTISLLDALQGFTMEIKHLDGHK--VKITREKVTWPGATIRKSNEGMPNY 635
+R G+DL+ I L++AL GF KHLD + VK KV PG EGMP Y
Sbjct: 261 QRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQIVVKYPPGKVIEPGCVRVVRGEGMPQY 320
Query: 636 ENNHVKGSLYITIDVAFPKD 695
N KG LYI DV FP++
Sbjct: 321 RNPFEKGDLYIKFDVQFPEN 340
>sp|Q94AW8|DNAJ3_ARATH Chaperone protein dnaJ 3 (AtJ3) (AtDjA3)
Length = 420
Score = 124 bits (311), Expect = 3e-28
Identities = 87/259 (33%), Positives = 129/259 (49%), Gaps = 32/259 (12%)
Frame = +3
Query: 9 GGSSMDPF---SSFFGDVFFDMGGSRRQKDIPRGGDVIMDLFVSLEELYNGNFVEVVRYK 179
GG DPF SSFFG F G + RQ+ RG DV+ L VSLE++Y G ++ +
Sbjct: 86 GGGGHDPFDIFSSFFGGGPFG-GNTSRQRRQRRGEDVVHPLKVSLEDVYLGTMKKLSLSR 144
Query: 180 SV---KKSAHGTR-----KCN-CRHEMKTI---QTGPGRF---------------TMTQE 278
+ K + G++ KC C+ + Q GPG T+
Sbjct: 145 NALCSKCNGKGSKSGASLKCGGCQGSGMKVSIRQLGPGMIQQMQHACNECKGTGETINDR 204
Query: 279 QVCDECPNVRFVPEEKLLEVEIEPGMRDGQLYPFVAEGEPHIDGEPGDLKFRIRQSKHAR 458
C +C + +PE+K+LEV +E GM+ Q F + + D GD+ F ++Q +H +
Sbjct: 205 DRCPQCKGDKVIPEKKVLEVNVEKGMQHSQKITFEGQADEAPDTVTGDIVFVLQQKEHPK 264
Query: 459 FERRGDDLYTNVTISLLDALQGFTMEIKHLDGHK--VKITREKVTWPGATIRKSNEGMPN 632
F+R+G+DL+ T+SL +AL GF + HLDG +K +V P + S+EGMP
Sbjct: 265 FKRKGEDLFVEHTLSLTEALCGFQFVLTHLDGRSLLIKSNPGEVVKPDSYKAISDEGMPI 324
Query: 633 YENNHVKGSLYITIDVAFP 689
Y+ +KG LYI V FP
Sbjct: 325 YQRPFMKGKLYIHFTVEFP 343
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,754,088
Number of Sequences: 369166
Number of extensions: 1910824
Number of successful extensions: 5722
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5124
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5367
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8100769320
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)