Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_B10
(800 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8WW22|DNJA4_HUMAN DnaJ homolog subfamily A member 4 259 5e-69
sp|Q9JMC3|DNJA4_MOUSE DnaJ homolog subfamily A member 4 (Mm... 256 4e-68
sp|P31689|DNJA1_HUMAN DnaJ homolog subfamily A member 1 (He... 253 4e-67
sp|P63036|DNJA1_RAT DnaJ homolog subfamily A member 1 (DnaJ... 253 4e-67
sp|O60884|DNJA2_HUMAN DnaJ homolog subfamily A member 2 (HI... 236 4e-62
sp|Q9QYJ0|DNJA2_MOUSE DnaJ homolog subfamily A member 2 (mDj3) 235 9e-62
sp|O35824|DNJA2_RAT DnaJ homolog subfamily A member 2 (RDJ2) 233 3e-61
sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2 233 5e-61
sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (DNAJ-1) 231 1e-60
sp|Q94AW8|DNAJ3_ARATH Chaperone protein dnaJ 3 (AtJ3) (AtDjA3) 221 2e-57
>sp|Q8WW22|DNJA4_HUMAN DnaJ homolog subfamily A member 4
Length = 397
Score = 259 bits (663), Expect = 5e-69
Identities = 128/248 (51%), Positives = 176/248 (70%)
Frame = +2
Query: 2 EVHIRQLGPGMVQQMQTTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTD 181
++HI+Q+GPGMVQQ+QT C CKG+ E IN +DRC+ C G KV+REKK++EVH++KGM D
Sbjct: 160 QIHIQQIGPGMVQQIQTVCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKGMKD 219
Query: 182 GQQIKFNGEGDQEPGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTIT 361
GQ+I F+GEGDQEP LEPGD+ IVL++K H+VF R+ DLI MK+ L ++LCGFK+TI
Sbjct: 220 GQKILFHGEGDQEPELEPGDVIIVLDQKDHSVFQRRGHDLIMKMKIQLSEALCGFKKTIK 279
Query: 362 TLDNRILVVETKPGEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDK 541
TLDNRILV+ +K GEVIK+ + R + +EGMP YK+P E+G LIIQF V+FPE ++L +K
Sbjct: 280 TLDNRILVITSKAGEVIKHGDLRCVRDEGMPIYKAPLEKGILIIQFLVIFPEKHWLSLEK 339
Query: 542 LNKLRSILPPSQFSSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMP 721
L +L ++LPP Q D+M + E L + P+ N + + Y+ D++G
Sbjct: 340 LPQLEALLPPRQKVRITDDMDQVE---LKEFCPNEQN------WRQHREAYEEDEDGPQA 390
Query: 722 GGAQRVQC 745
G VQC
Sbjct: 391 G----VQC 394
>sp|Q9JMC3|DNJA4_MOUSE DnaJ homolog subfamily A member 4 (MmDjA4)
Length = 397
Score = 256 bits (655), Expect = 4e-68
Identities = 127/248 (51%), Positives = 174/248 (70%)
Frame = +2
Query: 2 EVHIRQLGPGMVQQMQTTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTD 181
+VHI+Q+GPGMVQQ+QT C CKG+ E IN +DRC+ C G KV REKK++EVH++KGM D
Sbjct: 160 QVHIQQIGPGMVQQIQTVCIECKGQGERINPKDRCENCSGAKVTREKKIIEVHVEKGMKD 219
Query: 182 GQQIKFNGEGDQEPGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTIT 361
GQ+I F+GEGDQEP L+PGD+ IVL++K H+VF R+ DLI MK+ L ++LCGFK+TI
Sbjct: 220 GQKILFHGEGDQEPELDPGDVIIVLDQKDHSVFQRRGQDLIMKMKIQLSEALCGFKKTIK 279
Query: 362 TLDNRILVVETKPGEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDK 541
TLD+R+LV+ +K GEVIK+ + + I NEGMP YK+P E+G +IIQF VVFPE +L +K
Sbjct: 280 TLDDRVLVISSKSGEVIKHGDLKCIRNEGMPIYKAPLEKGVMIIQFLVVFPEKQWLSQEK 339
Query: 542 LNKLRSILPPSQFSSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMP 721
L +L ++LPP Q D+M + E L ++P ++ + + Y+ DDE
Sbjct: 340 LPQLEALLPPRQKVRITDDMDQVE---LKEFNP------NEQSWRQHREAYEEDDEEPRA 390
Query: 722 GGAQRVQC 745
G VQC
Sbjct: 391 G----VQC 394
>sp|P31689|DNJA1_HUMAN DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4)
(DnaJ protein homolog 2) (HSJ-2) (HSDJ)
Length = 397
Score = 253 bits (646), Expect = 4e-67
Identities = 125/244 (51%), Positives = 169/244 (69%)
Frame = +2
Query: 2 EVHIRQLGPGMVQQMQTTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTD 181
++ I Q+GPGMVQQ+Q+ C C+G E I+ +DRCK C G+K+VREKK+LEVHIDKGM D
Sbjct: 159 QIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKD 218
Query: 182 GQQIKFNGEGDQEPGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTIT 361
GQ+I F+GEGDQEPGLEPGDI IVL++K H VFTR+ DL M + LV++LCGF++ I+
Sbjct: 219 GQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPIS 278
Query: 362 TLDNRILVVETKPGEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDK 541
TLDNR +V+ + PG+++K+ + + + NEGMP Y+ P+E+GRLII+F V FPEN FL DK
Sbjct: 279 TLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDK 338
Query: 542 LNKLRSILPPSQFSSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMP 721
L+ L +LP + D M + E L +DP+ + R H Y+ DDE
Sbjct: 339 LSLLEKLLPERKEVEETDEMDQVE---LVDFDPN-----QERRRHYNGEAYE-DDEHHPR 389
Query: 722 GGAQ 733
GG Q
Sbjct: 390 GGVQ 393
>sp|P63036|DNJA1_RAT DnaJ homolog subfamily A member 1 (DnaJ-like protein 1)
sp|P63037|DNJA1_MOUSE DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4)
(DnaJ protein homolog 2) (HSJ-2)
Length = 397
Score = 253 bits (646), Expect = 4e-67
Identities = 125/244 (51%), Positives = 169/244 (69%)
Frame = +2
Query: 2 EVHIRQLGPGMVQQMQTTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTD 181
++ I Q+GPGMVQQ+Q+ C C+G E I+ +DRCK C G+K+VREKK+LEVHIDKGM D
Sbjct: 159 QIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKD 218
Query: 182 GQQIKFNGEGDQEPGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTIT 361
GQ+I F+GEGDQEPGLEPGDI IVL++K H VFTR+ DL M + LV++LCGF++ I+
Sbjct: 219 GQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPIS 278
Query: 362 TLDNRILVVETKPGEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDK 541
TLDNR +V+ + PG+++K+ + + + NEGMP Y+ P+E+GRLII+F V FPEN FL DK
Sbjct: 279 TLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDK 338
Query: 542 LNKLRSILPPSQFSSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMP 721
L+ L +LP + D M + E L +DP+ + R H Y+ DDE
Sbjct: 339 LSLLEKLLPERKEVEETDEMDQVE---LVDFDPN-----QERRRHYNGEAYE-DDEHHPR 389
Query: 722 GGAQ 733
GG Q
Sbjct: 390 GGVQ 393
>sp|O60884|DNJA2_HUMAN DnaJ homolog subfamily A member 2 (HIRA interacting protein 4)
(Cell cycle progression restoration gene 3 protein)
(Dnj3)
Length = 412
Score = 236 bits (603), Expect = 4e-62
Identities = 123/248 (49%), Positives = 161/248 (64%)
Frame = +2
Query: 5 VHIRQLGPGMVQQMQTTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDG 184
+ IRQL PGMVQQMQ+ C C GE EVINE+DRCKKCEG+KV++E K+LEVH+DKGM G
Sbjct: 169 IMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHG 228
Query: 185 QQIKFNGEGDQEPGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITT 364
Q+I F GE DQ PG+EPGDI ++L+EK H VF R DL K+ LV++LCGF+ T
Sbjct: 229 QRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKH 288
Query: 365 LDNRILVVETKPGEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKL 544
LD R +VV+ PG+VI+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL
Sbjct: 289 LDGRQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKL 348
Query: 545 NKLRSILPPSQFSSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPG 724
++L +LP ++ + E EE L +D + + Q R DS DE
Sbjct: 349 SELEDLLPSRPEVPNI--IGETEEVELQEFDSTRGSGGGQ----RREAYNDSSDEESSSH 402
Query: 725 GAQRVQCA 748
VQCA
Sbjct: 403 HGPGVQCA 410
>sp|Q9QYJ0|DNJA2_MOUSE DnaJ homolog subfamily A member 2 (mDj3)
Length = 412
Score = 235 bits (600), Expect = 9e-62
Identities = 123/248 (49%), Positives = 161/248 (64%)
Frame = +2
Query: 5 VHIRQLGPGMVQQMQTTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDG 184
+ IRQL PGMVQQMQ+ C C GE EVINE+DRCKKCEG+KV++E K+LEVH+DKGM G
Sbjct: 169 IMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHG 228
Query: 185 QQIKFNGEGDQEPGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITT 364
Q+I F GE DQ PG+EPGDI ++L+EK H VF R DL K+ LV++LCGF+ T
Sbjct: 229 QRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKH 288
Query: 365 LDNRILVVETKPGEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKL 544
LD R +VV+ PG+VI+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL
Sbjct: 289 LDARQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKL 348
Query: 545 NKLRSILPPSQFSSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPG 724
++L +LP ++ + E EE L +D + + Q R DS DE
Sbjct: 349 SELEDLLPSRPEVPNV--IGETEEVELQEFDSTRGSGGGQ----RREAYNDSSDEESSSH 402
Query: 725 GAQRVQCA 748
VQCA
Sbjct: 403 HGPGVQCA 410
>sp|O35824|DNJA2_RAT DnaJ homolog subfamily A member 2 (RDJ2)
Length = 412
Score = 233 bits (595), Expect = 3e-61
Identities = 122/248 (49%), Positives = 160/248 (64%)
Frame = +2
Query: 5 VHIRQLGPGMVQQMQTTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDG 184
+ IRQL PGMVQQMQ+ C C GE EVINE+DRCKKCEG+KV++E K+LEVH+DKGM G
Sbjct: 169 IMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHG 228
Query: 185 QQIKFNGEGDQEPGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITT 364
Q+I F GE DQ PG+EPGDI + ++EK H VF R DL K+ LV++LCGF+ T
Sbjct: 229 QRITFTGEADQAPGVEPGDIVLFVQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKH 288
Query: 365 LDNRILVVETKPGEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKL 544
LD R +VV+ PG+VI+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL
Sbjct: 289 LDARQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKL 348
Query: 545 NKLRSILPPSQFSSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPG 724
++L +LP ++ + E EE L +D + + Q R DS DE
Sbjct: 349 SELEDLLPSRPEVPNV--IGETEEVELQEFDSTRGSGGGQ----RREAYNDSSDEESSSH 402
Query: 725 GAQRVQCA 748
VQCA
Sbjct: 403 HGPGVQCA 410
>sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2
Length = 418
Score = 233 bits (594), Expect = 5e-61
Identities = 121/251 (48%), Positives = 170/251 (67%), Gaps = 2/251 (0%)
Frame = +2
Query: 2 EVHIRQLGPGMVQQMQTTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTD 181
+V IRQLGPGM+QQMQ C CKG E+I+++DRC +C+G+KVV++KKVLEVH++KGM +
Sbjct: 173 KVSIRQLGPGMIQQMQHPCNECKGTGEMISDKDRCPQCKGEKVVQQKKVLEVHVEKGMQN 232
Query: 182 GQQIKFNGEGDQEPGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTIT 361
GQ+I F GE D+ P GDI VL++K H F RK DL Y L L ++LCGF+ +T
Sbjct: 233 GQKITFPGEADEAPDTVTGDIVFVLQQKEHPKFKRKGDDLFYEHSLSLTEALCGFQFVLT 292
Query: 362 TLDNRILVVETKPGEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDK 541
LDNR L++++ PGEVIK +++ I++EGMP Y+ PF +G+L I F V FP++ L D+
Sbjct: 293 HLDNRQLLIKSNPGEVIKPDQFKGINDEGMPMYQRPFMRGKLYIHFSVDFPDS--LTPDQ 350
Query: 542 LNKLRSILPPSQFSSSLDNMK--EAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGG 715
L S+L PS+ +S L +M+ E EE +H D ++ + ++ + YD DDEG
Sbjct: 351 CKALESVL-PSRNASRLTDMEIDECEETTMH--DVNIEEEMRRKQHQQAQEAYDEDDEG- 406
Query: 716 MPGGAQRVQCA 748
GGAQRVQCA
Sbjct: 407 -HGGAQRVQCA 416
>sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (DNAJ-1)
Length = 397
Score = 231 bits (590), Expect = 1e-60
Identities = 120/250 (48%), Positives = 164/250 (65%), Gaps = 1/250 (0%)
Frame = +2
Query: 2 EVHIRQLGPGMVQQMQTTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTD 181
+V IRQLGPGM+QQMQ C CKG E+IN++DRC C+G+KVV+EKKVLEVH++KGM +
Sbjct: 152 KVSIRQLGPGMIQQMQHPCNDCKGTGEMINDKDRCPLCKGEKVVQEKKVLEVHVEKGMQN 211
Query: 182 GQQIKFNGEGDQEPGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTIT 361
GQ+I F GE D+ P GDI VL++K H F RK DL Y L L ++LCGF+ +T
Sbjct: 212 GQRITFPGEADEAPDTVTGDIVFVLQQKEHPKFQRKGDDLFYKHTLSLTEALCGFQFVLT 271
Query: 362 TLDNRILVVETKPGEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDK 541
LD R L++++ PGEV+K +++AI++EGMP Y+ PF +G+L IQF V FP++ L D+
Sbjct: 272 HLDGRQLLIKSNPGEVVKPDQFKAINDEGMPMYQRPFMRGKLYIQFLVDFPDS--LTPDQ 329
Query: 542 LNKLRSILPPSQFSSSLD-NMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGM 718
+ S+LP S S D + E EE +H D ++ + ++ YD DDEG
Sbjct: 330 CKVIESVLPRSASSQLTDMEIDECEETTMH--DVNIEEEMRRKQHQHAQEAYDEDDEG-- 385
Query: 719 PGGAQRVQCA 748
GG QRVQCA
Sbjct: 386 HGGGQRVQCA 395
>sp|Q94AW8|DNAJ3_ARATH Chaperone protein dnaJ 3 (AtJ3) (AtDjA3)
Length = 420
Score = 221 bits (563), Expect = 2e-57
Identities = 116/250 (46%), Positives = 157/250 (62%), Gaps = 1/250 (0%)
Frame = +2
Query: 2 EVHIRQLGPGMVQQMQTTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTD 181
+V IRQLGPGM+QQMQ C CKG E IN+RDRC +C+G KV+ EKKVLEV+++KGM
Sbjct: 173 KVSIRQLGPGMIQQMQHACNECKGTGETINDRDRCPQCKGDKVIPEKKVLEVNVEKGMQH 232
Query: 182 GQQIKFNGEGDQEPGLEPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTIT 361
Q+I F G+ D+ P GDI VL++K H F RK DL L L ++LCGF+ +T
Sbjct: 233 SQKITFEGQADEAPDTVTGDIVFVLQQKEHPKFKRKGEDLFVEHTLSLTEALCGFQFVLT 292
Query: 362 TLDNRILVVETKPGEVIKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDK 541
LD R L++++ PGEV+K Y+AI +EGMP Y+ PF +G+L I F V FP++ L D+
Sbjct: 293 HLDGRSLLIKSNPGEVVKPDSYKAISDEGMPIYQRPFMKGKLYIHFTVEFPDS--LSPDQ 350
Query: 542 LNKLRSILP-PSQFSSSLDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGM 718
L ++LP PS S + E EE LH D ++ + + +R D D++
Sbjct: 351 TKALEAVLPKPSTAQLSDMEIDECEETTLH--DVNIEDEMRRKAQAQREAYDDDDEDDDH 408
Query: 719 PGGAQRVQCA 748
PGGAQRVQCA
Sbjct: 409 PGGAQRVQCA 418
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,234,209
Number of Sequences: 369166
Number of extensions: 1670970
Number of successful extensions: 5543
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5056
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5286
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7570361805
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)