Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_A14
(293 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P07858|CATB_HUMAN Cathepsin B precursor (Cathepsin B1) (... 146 1e-35
sp|P07688|CATB_BOVIN Cathepsin B precursor [Contains: Cathe... 140 9e-34
sp|P25792|CYSP_SCHMA Cathepsin B-like cysteine proteinase p... 135 3e-32
sp|P00787|CATB_RAT Cathepsin B precursor (Cathepsin B1) (RS... 133 1e-31
sp|P10605|CATB_MOUSE Cathepsin B precursor (Cathepsin B1) [... 133 1e-31
sp|P43233|CATB_CHICK Cathepsin B precursor (Cathepsin B1) [... 132 3e-31
sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4... 129 2e-30
sp|P43157|CYSP_SCHJA Cathepsin B-like cysteine proteinase p... 127 1e-29
sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5... 126 2e-29
sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precu... 122 3e-28
>sp|P07858|CATB_HUMAN Cathepsin B precursor (Cathepsin B1) (APP secretase) (APPS)
[Contains: Cathepsin B light chain; Cathepsin B heavy
chain]
Length = 339
Score = 146 bits (369), Expect = 1e-35
Identities = 65/78 (83%), Positives = 69/78 (88%)
Frame = +2
Query: 2 FSVYADFPNYKSGVYQHVTGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKI 181
FSVY+DF YKSGVYQHVTG M+GGHAI+ILGWGVEN TPYWLVANSWN WGDNG+FKI
Sbjct: 253 FSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKI 312
Query: 182 LRGSDECGIEDEVVAGIP 235
LRG D CGIE EVVAGIP
Sbjct: 313 LRGQDHCGIESEVVAGIP 330
>sp|P07688|CATB_BOVIN Cathepsin B precursor [Contains: Cathepsin B light chain; Cathepsin
B heavy chain]
Length = 335
Score = 140 bits (353), Expect = 9e-34
Identities = 60/78 (76%), Positives = 68/78 (87%)
Frame = +2
Query: 2 FSVYADFPNYKSGVYQHVTGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKI 181
FSVY+DF YKSGVYQHV+G ++GGHAI+ILGWGVEN TPYWLV NSWN WGDNG+FKI
Sbjct: 253 FSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKI 312
Query: 182 LRGSDECGIEDEVVAGIP 235
LRG D CGIE E+VAG+P
Sbjct: 313 LRGQDHCGIESEIVAGMP 330
>sp|P25792|CYSP_SCHMA Cathepsin B-like cysteine proteinase precursor (Antigen Sm31)
Length = 340
Score = 135 bits (340), Expect = 3e-32
Identities = 55/76 (72%), Positives = 66/76 (86%)
Frame = +2
Query: 2 FSVYADFPNYKSGVYQHVTGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKI 181
F+VY DF NYKSG+Y+H+TG LGGHAI+I+GWGVEN TPYWL+ANSWN WG+NGYF+I
Sbjct: 262 FTVYEDFLNYKSGIYKHITGEALGGHAIRIIGWGVENKTPYWLIANSWNEDWGENGYFRI 321
Query: 182 LRGSDECGIEDEVVAG 229
+RG DEC IE EV+AG
Sbjct: 322 VRGRDECSIESEVIAG 337
>sp|P00787|CATB_RAT Cathepsin B precursor (Cathepsin B1) (RSG-2) [Contains: Cathepsin B
light chain; Cathepsin B heavy chain]
Length = 339
Score = 133 bits (334), Expect = 1e-31
Identities = 55/78 (70%), Positives = 66/78 (84%)
Frame = +2
Query: 2 FSVYADFPNYKSGVYQHVTGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKI 181
F+V++DF YKSGVY+H G ++GGHAI+ILGWG+EN PYWLVANSWN WGDNG+FKI
Sbjct: 253 FTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKI 312
Query: 182 LRGSDECGIEDEVVAGIP 235
LRG + CGIE E+VAGIP
Sbjct: 313 LRGENHCGIESEIVAGIP 330
>sp|P10605|CATB_MOUSE Cathepsin B precursor (Cathepsin B1) [Contains: Cathepsin B light
chain; Cathepsin B heavy chain]
Length = 339
Score = 133 bits (334), Expect = 1e-31
Identities = 56/78 (71%), Positives = 65/78 (83%)
Frame = +2
Query: 2 FSVYADFPNYKSGVYQHVTGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKI 181
F+V++DF YKSGVY+H G M+GGHAI+ILGWGVEN PYWL ANSWN WGDNG+FKI
Sbjct: 253 FTVFSDFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGFFKI 312
Query: 182 LRGSDECGIEDEVVAGIP 235
LRG + CGIE E+VAGIP
Sbjct: 313 LRGENHCGIESEIVAGIP 330
>sp|P43233|CATB_CHICK Cathepsin B precursor (Cathepsin B1) [Contains: Cathepsin B light
chain; Cathepsin B heavy chain]
Length = 340
Score = 132 bits (331), Expect = 3e-31
Identities = 57/78 (73%), Positives = 63/78 (80%)
Frame = +2
Query: 2 FSVYADFPNYKSGVYQHVTGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKI 181
F VY DF YKSGVYQHV+G +GGHAI+ILGWGVEN TPYWL ANSWN WG G+FKI
Sbjct: 254 FIVYEDFLMYKSGVYQHVSGEQVGGHAIRILGWGVENGTPYWLAANSWNTDWGITGFFKI 313
Query: 182 LRGSDECGIEDEVVAGIP 235
LRG D CGIE E+VAG+P
Sbjct: 314 LRGEDHCGIESEIVAGVP 331
>sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4 precursor (Cysteine
protease-related 4)
Length = 335
Score = 129 bits (325), Expect = 2e-30
Identities = 54/78 (69%), Positives = 64/78 (82%)
Frame = +2
Query: 2 FSVYADFPNYKSGVYQHVTGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKI 181
F+VY DF YK+GVY H TG LGGHAI+ILGWG +N TPYWLVANSWN WG+NGYF+I
Sbjct: 256 FTVYEDFYQYKTGVYVHTTGQELGGHAIRILGWGTDNGTPYWLVANSWNVNWGENGYFRI 315
Query: 182 LRGSDECGIEDEVVAGIP 235
+RG++ECGIE VV G+P
Sbjct: 316 IRGTNECGIEHAVVGGVP 333
>sp|P43157|CYSP_SCHJA Cathepsin B-like cysteine proteinase precursor (Antigen Sj31)
Length = 342
Score = 127 bits (318), Expect = 1e-29
Identities = 51/77 (66%), Positives = 64/77 (83%)
Frame = +2
Query: 2 FSVYADFPNYKSGVYQHVTGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKI 181
F VY DF NYKSG+Y+HVTG ++GGHAI+I+GWGVE TPYWL+ANSWN WG+ G F++
Sbjct: 263 FDVYEDFLNYKSGIYRHVTGSIVGGHAIRIIGWGVEKRTPYWLIANSWNEDWGEKGLFRM 322
Query: 182 LRGSDECGIEDEVVAGI 232
+RG DEC IE +VVAG+
Sbjct: 323 VRGRDECSIESDVVAGL 339
>sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5 precursor (Cysteine
protease-related 5)
Length = 344
Score = 126 bits (316), Expect = 2e-29
Identities = 53/78 (67%), Positives = 61/78 (78%)
Frame = +2
Query: 2 FSVYADFPNYKSGVYQHVTGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKI 181
F+VY DF Y +GVY H G LGGHA+KILGWGV+N TPYWLVANSWN WG+ GYF+I
Sbjct: 261 FTVYEDFYQYTTGVYVHTAGASLGGHAVKILGWGVDNGTPYWLVANSWNVAWGEKGYFRI 320
Query: 182 LRGSDECGIEDEVVAGIP 235
+RG +ECGIE VAGIP
Sbjct: 321 IRGLNECGIEHSAVAGIP 338
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor
Length = 329
Score = 122 bits (306), Expect = 3e-28
Identities = 52/76 (68%), Positives = 60/76 (78%)
Frame = +2
Query: 2 FSVYADFPNYKSGVYQHVTGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKI 181
FSVY DF YKSGVY+H G LGGHAIKI+GWG E+ +PYWLVANSW WG++G+FKI
Sbjct: 250 FSVYEDFYKYKSGVYKHTAGKYLGGHAIKIIGWGTESGSPYWLVANSWGVNWGESGFFKI 309
Query: 182 LRGSDECGIEDEVVAG 229
RG D+CGIE VVAG
Sbjct: 310 YRGDDQCGIESAVVAG 325
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,677,266
Number of Sequences: 369166
Number of extensions: 686725
Number of successful extensions: 1768
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1722
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1738
length of database: 68,354,980
effective HSP length: 67
effective length of database: 55,977,735
effective search space used: 1679332050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)