Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_P24
(800 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P57737|CORO7_HUMAN Coronin-7 (70 kDa WD repeat tumor rej... 41 0.003
sp|Q8BG40|KTNB1_MOUSE Katanin p80 WD40-containing subunit B... 40 0.006
sp|Q9BVA0|KTNB1_HUMAN Katanin p80 WD40-containing subunit B... 40 0.006
sp|P56093|TUP1_CANAL Transcriptional repressor TUP1 40 0.006
sp|Q7ZUV2|KTNB1_BRARE Katanin p80 WD40-containing subunit B... 40 0.006
sp|P07834|CDC4_YEAST Cell division control protein 4 40 0.006
sp|P61964|WDR5_HUMAN WD-repeat protein 5 (BMP2-induced 3-kb... 40 0.010
sp|P25635|PWP2_YEAST Periodic tryptophan protein 2 (U3 smal... 39 0.013
sp|P56094|TUP1_KLULA Transcriptional repressor TUP1 39 0.013
sp|Q8YTC2|Y2800_ANASP Hypothetical WD-repeat protein alr2800 39 0.013
>sp|P57737|CORO7_HUMAN Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog)
Length = 925
Score = 41.2 bits (95), Expect = 0.003
Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Frame = +1
Query: 508 FDGGRCVTAGEDSVIRVYDLVAK--KEINKCYSTNSADKMDGHIMRICAVQYHPRGQTEE 681
FD R AGED+ IR++ + A+ +E+ T + GH +IC++++HP
Sbjct: 555 FDPHRLAVAGEDARIRLWRVPAEGLEEV----LTTPETVLTGHTEKICSLRFHP------ 604
Query: 682 LYSHIFISGGWDDSIQIWD 738
L +++ S +D +++IWD
Sbjct: 605 LAANVLASSSYDLTVRIWD 623
>sp|Q8BG40|KTNB1_MOUSE Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1)
(p80 katanin)
Length = 658
Score = 40.4 bits (93), Expect = 0.006
Identities = 24/83 (28%), Positives = 37/83 (44%)
Frame = +1
Query: 526 VTAGEDSVIRVYDLVAKKEINKCYSTNSADKMDGHIMRICAVQYHPRGQTEELYSHIFIS 705
V + IRV+DL A K + + GH IC++ +HP Y S
Sbjct: 79 VAGSQSGSIRVWDLEAAKILRT---------LMGHKANICSLDFHP-------YGEFVAS 122
Query: 706 GGWDDSIQIWDDRHSRSLWQYYG 774
G D +I++WD R +++Y G
Sbjct: 123 GSQDTNIKLWDIRRKGCVFRYRG 145
>sp|Q9BVA0|KTNB1_HUMAN Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1)
(p80 katanin)
Length = 655
Score = 40.4 bits (93), Expect = 0.006
Identities = 24/83 (28%), Positives = 37/83 (44%)
Frame = +1
Query: 526 VTAGEDSVIRVYDLVAKKEINKCYSTNSADKMDGHIMRICAVQYHPRGQTEELYSHIFIS 705
V + IRV+DL A K + + GH IC++ +HP Y S
Sbjct: 79 VAGSQSGSIRVWDLEAAKILRT---------LMGHKANICSLDFHP-------YGEFVAS 122
Query: 706 GGWDDSIQIWDDRHSRSLWQYYG 774
G D +I++WD R +++Y G
Sbjct: 123 GSQDTNIKLWDIRRKGCVFRYRG 145
>sp|P56093|TUP1_CANAL Transcriptional repressor TUP1
Length = 514
Score = 40.4 bits (93), Expect = 0.006
Identities = 40/147 (27%), Positives = 63/147 (42%), Gaps = 2/147 (1%)
Frame = +1
Query: 319 IATYASGHMKIWHYTAATAKSRLVASFLEEKILRPNEPRKSITGKEGKVIVKQYNQIMTC 498
IAT + ++++ T LVA ++E NE + T G + ++
Sbjct: 217 IATGCNKTTQVFNVTTG----ELVAKLIDES---SNENKDDNTTASGDLYIR-------- 261
Query: 499 SVSF--DGGRCVTAGEDSVIRVYDLVAKKEINKCYSTNSADKMDGHIMRICAVQYHPRGQ 672
SV F DG T ED +IR++DL K+ I + GH I ++ + P G
Sbjct: 262 SVCFSPDGKLLATGAEDKLIRIWDLSTKRIIK---------ILRGHEQDIYSLDFFPDGD 312
Query: 673 TEELYSHIFISGGWDDSIQIWDDRHSR 753
+SG D S++IWD R S+
Sbjct: 313 R-------LVSGSGDRSVRIWDLRTSQ 332
>sp|Q7ZUV2|KTNB1_BRARE Katanin p80 WD40-containing subunit B1 homolog
Length = 694
Score = 40.4 bits (93), Expect = 0.006
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Frame = +1
Query: 472 KQYNQIMTC-SVSFDGGRCVTAGEDSVIRVYDLVAKKEINKCYSTNSADKMDGHIMRICA 648
K + Q + C + S DG +A +DS ++++DL+A K I + S SA +
Sbjct: 144 KGHTQAVRCLAFSPDGKWLASASDDSTVKLWDLIAGKMITEFTSHTSA---------VNV 194
Query: 649 VQYHPRGQTEELYSHIFISGGWDDSIQIWD 738
VQ+HP ++ SG D ++++WD
Sbjct: 195 VQFHPN-------EYLLASGSADRTVKLWD 217
>sp|P07834|CDC4_YEAST Cell division control protein 4
Length = 779
Score = 40.4 bits (93), Expect = 0.006
Identities = 31/127 (24%), Positives = 55/127 (43%)
Frame = +1
Query: 358 YTAATAKSRLVASFLEEKILRPNEPRKSITGKEGKVIVKQYNQIMTCSVSFDGGRCVTAG 537
Y + + RL SFLE + N + + ++TC + F+ +T
Sbjct: 342 YPKLSQQDRLRLSFLENIFILKNWYNPKFVPQR-TTLRGHMTSVITC-LQFEDNYVITGA 399
Query: 538 EDSVIRVYDLVAKKEINKCYSTNSADKMDGHIMRICAVQYHPRGQTEELYSHIFISGGWD 717
+D +IRVYD + KK + + + GH + A++Y G I +SG D
Sbjct: 400 DDKMIRVYDSINKKFLLQ---------LSGHDGGVWALKYAHGG--------ILVSGSTD 442
Query: 718 DSIQIWD 738
++++WD
Sbjct: 443 RTVRVWD 449
Score = 35.4 bits (80), Expect = 0.18
Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 6/90 (6%)
Frame = +1
Query: 520 RCVTAGEDSVIRVYDLVAKKEINKC-YSTNSADKMDGHIMRICAVQYHPRGQTE-----E 681
RC++A D+ IR++DL +C Y+TNSA +I Y +G T
Sbjct: 584 RCISASMDTTIRIWDLENIWNNGECSYATNSASP----CAKILGAMYTLQGHTALVGLLR 639
Query: 682 LYSHIFISGGWDDSIQIWDDRHSRSLWQYY 771
L +S D SI+ WD + Y+
Sbjct: 640 LSDKFLVSAAADGSIRGWDANDYSRKFSYH 669
>sp|P61964|WDR5_HUMAN WD-repeat protein 5 (BMP2-induced 3-kb gene protein)
sp|P61965|WDR5_MOUSE WD-repeat protein 5 (BMP2-induced 3-kb gene protein) (WD-repeat
protein BIG-3)
Length = 334
Score = 39.7 bits (91), Expect = 0.010
Identities = 32/142 (22%), Positives = 63/142 (44%)
Frame = +1
Query: 334 SGHMKIWHYTAATAKSRLVASFLEEKILRPNEPRKSITGKEGKVIVKQYNQIMTCSVSFD 513
+GH K + +AS +K+++ + GK K I I + S D
Sbjct: 42 AGHTKAVSSVKFSPNGEWLASSSADKLIKI---WGAYDGKFEKTISGHKLGISDVAWSSD 98
Query: 514 GGRCVTAGEDSVIRVYDLVAKKEINKCYSTNSADKMDGHIMRICAVQYHPRGQTEELYSH 693
V+A +D ++++D+ + KC T + GH + ++P+ S+
Sbjct: 99 SNLLVSASDDKTLKIWDVSS----GKCLKT-----LKGHSNYVFCCNFNPQ-------SN 142
Query: 694 IFISGGWDDSIQIWDDRHSRSL 759
+ +SG +D+S++IWD + + L
Sbjct: 143 LIVSGSFDESVRIWDVKTGKCL 164
>sp|P25635|PWP2_YEAST Periodic tryptophan protein 2 (U3 small nucleolar RNA-associated
protein 1) (U3 snoRNA-associated protein 1)
Length = 923
Score = 39.3 bits (90), Expect = 0.013
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 3/94 (3%)
Frame = +1
Query: 466 IVKQ---YNQIMTCSVSFDGGRCVTAGEDSVIRVYDLVAKKEINKCYSTNSADKMDGHIM 636
I+KQ ++ + + S DG R VTA ED I+V+D+ + C +T + H
Sbjct: 338 ILKQQGHFDSTNSLAYSPDGSRVVTASEDGKIKVWDITS----GFCLAT-----FEEHTS 388
Query: 637 RICAVQYHPRGQTEELYSHIFISGGWDDSIQIWD 738
+ AVQ+ RGQ + S D +++ WD
Sbjct: 389 SVTAVQFAKRGQ-------VMFSSSLDGTVRAWD 415
>sp|P56094|TUP1_KLULA Transcriptional repressor TUP1
Length = 682
Score = 39.3 bits (90), Expect = 0.013
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 2/100 (2%)
Frame = +1
Query: 445 TGKEGKVIVKQYNQIMTCSVSF--DGGRCVTAGEDSVIRVYDLVAKKEINKCYSTNSADK 618
TG + + + SV F DG T ED +IR++DL KK +
Sbjct: 393 TGNQNSAASTASSDLYIRSVCFSPDGKFLATGAEDKLIRIWDLETKKIVM---------T 443
Query: 619 MDGHIMRICAVQYHPRGQTEELYSHIFISGGWDDSIQIWD 738
+ GH I ++ Y P G +SG D +++IWD
Sbjct: 444 LKGHEQDIYSLDYFPSGNK-------LVSGSGDRTVRIWD 476
>sp|Q8YTC2|Y2800_ANASP Hypothetical WD-repeat protein alr2800
Length = 1258
Score = 39.3 bits (90), Expect = 0.013
Identities = 28/110 (25%), Positives = 49/110 (44%)
Frame = +1
Query: 445 TGKEGKVIVKQYNQIMTCSVSFDGGRCVTAGEDSVIRVYDLVAKKEINKCYSTNSADKMD 624
TG+ K + N + + + S D V+ D I+++D + + C T +
Sbjct: 841 TGECLKTYIGHTNSVYSIAYSPDSKILVSGSGDRTIKLWDC----QTHICIKT-----LH 891
Query: 625 GHIMRICAVQYHPRGQTEELYSHIFISGGWDDSIQIWDDRHSRSLWQYYG 774
GH +C+V + P GQT S D S+++W+ R + L +YG
Sbjct: 892 GHTNEVCSVAFSPDGQTLACVS-------LDQSVRLWNCRTGQCLKAWYG 934
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,946,301
Number of Sequences: 369166
Number of extensions: 2043766
Number of successful extensions: 5384
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4978
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5339
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7570361805
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)