Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_O23
(321 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O88281|EGFL3_RAT Multiple EGF-like-domain protein 3 prec... 33 0.20
sp|O35806|LTBP2_RAT Latent transforming growth factor-beta-... 30 1.3
sp|O08999|LTBP2_MOUSE Latent transforming growth factor-bet... 30 1.3
sp|Q01705|NOTC1_MOUSE Neurogenic locus notch homolog protei... 30 1.7
sp|Q07008|NOTC1_RAT Neurogenic locus notch homolog protein ... 30 1.7
sp|Q9XUC4|YGJK_CAEEL Hypothetical protein T28F3.3 in chromo... 30 2.2
sp|Q80V70|EGFL3_MOUSE Multiple EGF-like-domain protein 3 30 2.2
sp|P24821|TENA_HUMAN Tenascin precursor (TN) (Hexabrachion)... 30 2.2
sp|P11047|LAMC1_HUMAN Laminin gamma-1 chain precursor (Lami... 29 2.9
sp|Q99466|NOTC4_HUMAN Neurogenic locus notch homolog protei... 29 3.8
>sp|O88281|EGFL3_RAT Multiple EGF-like-domain protein 3 precursor (Multiple epidermal
growth factor-like domains 6)
Length = 1574
Score = 33.1 bits (74), Expect = 0.20
Identities = 12/26 (46%), Positives = 14/26 (53%)
Frame = +3
Query: 75 PGVTAGHCDDGCHDTKAKPHCDDGCH 152
PGV+ HC+DGC HC CH
Sbjct: 591 PGVSGAHCEDGCPKGFYGKHCRKKCH 616
>sp|O35806|LTBP2_RAT Latent transforming growth factor-beta-binding protein 2 precursor
(LTBP-2)
Length = 1764
Score = 30.4 bits (67), Expect = 1.3
Identities = 14/42 (33%), Positives = 22/42 (52%)
Frame = +3
Query: 60 DDCHKPGVTAGHCDDGCHDTKAKPHCDDGCHAPGVKSDHCKD 185
D+C +PGV +G C +T+ HC+ V+ HC+D
Sbjct: 922 DECEQPGVCSG---GRCSNTEGSYHCECDQGYVMVRRGHCQD 960
>sp|O08999|LTBP2_MOUSE Latent transforming growth factor-beta-binding protein 2 precursor
(LTBP-2)
Length = 1813
Score = 30.4 bits (67), Expect = 1.3
Identities = 14/42 (33%), Positives = 22/42 (52%)
Frame = +3
Query: 60 DDCHKPGVTAGHCDDGCHDTKAKPHCDDGCHAPGVKSDHCKD 185
D+C +PGV +G C +T+ HC+ V+ HC+D
Sbjct: 923 DECEQPGVCSG---GRCSNTEGSYHCECDRGYIMVRKGHCQD 961
>sp|Q01705|NOTC1_MOUSE Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch
A) (mT14) (p300) [Contains: Notch 1 extracellular
truncation; Notch 1 intracellular domain]
Length = 2531
Score = 30.0 bits (66), Expect = 1.7
Identities = 15/48 (31%), Positives = 20/48 (41%), Gaps = 13/48 (27%)
Frame = +3
Query: 51 HCKDDCHKPG---------VTAGHC----DDGCHDTKAKPHCDDGCHA 155
HC C+ G +T G C D C D + HCD GC++
Sbjct: 1504 HCDSQCNSAGCLFDGFDCQLTEGQCNPLYDQYCKDHFSDGHCDQGCNS 1551
>sp|Q07008|NOTC1_RAT Neurogenic locus notch homolog protein 1 precursor (Notch 1)
[Contains: Notch 1 extracellular truncation; Notch 1
intracellular domain]
Length = 2531
Score = 30.0 bits (66), Expect = 1.7
Identities = 15/48 (31%), Positives = 20/48 (41%), Gaps = 13/48 (27%)
Frame = +3
Query: 51 HCKDDCHKPG---------VTAGHC----DDGCHDTKAKPHCDDGCHA 155
HC C+ G +T G C D C D + HCD GC++
Sbjct: 1504 HCDSQCNSAGCLFDGFDCQLTEGQCNPLYDQYCKDHFSDGHCDQGCNS 1551
>sp|Q9XUC4|YGJK_CAEEL Hypothetical protein T28F3.3 in chromosome IV
Length = 393
Score = 29.6 bits (65), Expect = 2.2
Identities = 12/29 (41%), Positives = 15/29 (51%)
Frame = -1
Query: 174 DLTSHQEHDIHHHNEALLLYRDNHHRNAQ 88
+L H EHD HH+E L+ HR Q
Sbjct: 46 ELHDHHEHDHDHHDEQLIRKNHTSHREIQ 74
>sp|Q80V70|EGFL3_MOUSE Multiple EGF-like-domain protein 3
Length = 656
Score = 29.6 bits (65), Expect = 2.2
Identities = 12/38 (31%), Positives = 15/38 (39%), Gaps = 1/38 (2%)
Frame = +3
Query: 51 HCKDDCH-KPGVTAGHCDDGCHDTKAKPHCDDGCHAPG 161
H +CH PG T C+ C C+ C PG
Sbjct: 271 HVSGECHCPPGFTGPGCEQACQPGTFGKDCEHPCQCPG 308
Score = 28.9 bits (63), Expect = 3.8
Identities = 10/25 (40%), Positives = 13/25 (52%)
Frame = +3
Query: 75 PGVTAGHCDDGCHDTKAKPHCDDGC 149
PG T GHC+ GC + C+ C
Sbjct: 410 PGKTGGHCERGCPQDRFGKGCEHKC 434
>sp|P24821|TENA_HUMAN Tenascin precursor (TN) (Hexabrachion) (Cytotactin) (Neuronectin)
(GMEM) (JI) (Miotendinous antigen)
(Glioma-associated-extracellular matrix antigen) (GP
150-225) (Tenascin-C) (TN-C)
Length = 2201
Score = 29.6 bits (65), Expect = 2.2
Identities = 19/68 (27%), Positives = 24/68 (35%), Gaps = 21/68 (30%)
Frame = +3
Query: 54 CKDDCHKPGVTAGH---CDDG-----CHDTKAKPHC-------------DDGCHAPGVKS 170
C +DCH+ G CDDG C D + C +DG P
Sbjct: 470 CPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAE 529
Query: 171 DHCKDDCH 194
C +DCH
Sbjct: 530 LSCPNDCH 537
>sp|P11047|LAMC1_HUMAN Laminin gamma-1 chain precursor (Laminin B2 chain)
Length = 1609
Score = 29.3 bits (64), Expect = 2.9
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 21/68 (30%)
Frame = +3
Query: 48 EHCKDDCHKPGVTAGHCDDGCHDTKAKP-----HCDD----------------GCHAPGV 164
E C DCH G T G CD + +P HC+ CH G
Sbjct: 933 ERC--DCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGS 990
Query: 165 KSDHCKDD 188
S CKDD
Sbjct: 991 LSLQCKDD 998
>sp|Q99466|NOTC4_HUMAN Neurogenic locus notch homolog protein 4 precursor (Notch 4)
(hNotch4) [Contains: Notch 4 extracellular truncation;
Notch 4 intracellular domain]
Length = 2003
Score = 28.9 bits (63), Expect = 3.8
Identities = 11/30 (36%), Positives = 13/30 (43%)
Frame = +3
Query: 63 DCHKPGVTAGHCDDGCHDTKAKPHCDDGCH 152
DC P D CHD HC+ GC+
Sbjct: 1244 DCETPPACTPAYDQYCHDHFHNGHCEKGCN 1273
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,432,632
Number of Sequences: 369166
Number of extensions: 621141
Number of successful extensions: 1974
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1732
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1943
length of database: 68,354,980
effective HSP length: 75
effective length of database: 54,499,855
effective search space used: 1689495505
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)