Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_K13
(817 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P27867|DHSO_RAT Sorbitol dehydrogenase (L-iditol 2-dehyd... 229 5e-60
sp|Q64442|DHSO_MOUSE Sorbitol dehydrogenase (L-iditol 2-deh... 229 9e-60
sp|Q00796|DHSO_HUMAN Sorbitol dehydrogenase (L-iditol 2-deh... 225 1e-58
sp|P07846|DHSO_SHEEP Sorbitol dehydrogenase (L-iditol 2-deh... 224 2e-58
sp|Q02912|DHSO_BOMMO Sorbitol dehydrogenase (L-iditol 2-deh... 195 1e-49
sp|P35497|DHSO1_YEAST Sorbitol dehydrogenase 1 (L-iditol 2-... 192 9e-49
sp|Q07786|DHSO2_YEAST Sorbitol dehydrogenase 2 (L-iditol 2-... 190 5e-48
sp|P36624|DHSO_SCHPO Putative sorbitol dehydrogenase (L-idi... 188 1e-47
sp|Q06004|DHSO_BACSU Sorbitol dehydrogenase (L-iditol 2-deh... 178 1e-44
sp|P22144|XYL2_PICST D-xylulose reductase (Xylitol dehydrog... 177 4e-44
>sp|P27867|DHSO_RAT Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
Length = 399
Score = 229 bits (585), Expect = 5e-60
Identities = 111/215 (51%), Positives = 156/215 (72%)
Frame = +2
Query: 2 KSPIILGHETSAVVIKCGAKVTKLKEGDRVAIEPGVPCRRCTLCVSGRYNLCSKVVFHAT 181
K P++LGHE + V K G V LK GDRVAIEPGVP C GRYNL + F AT
Sbjct: 105 KKPMVLGHEAAGTVTKVGPMVKHLKPGDRVAIEPGVpreIDEFCKIGRYNLTPSIFFCAT 164
Query: 182 PPIDGTLCQYITHPEDFCFKLPDNVSNEEGALLEPLSVGVHACRRGNVTLGSKVLIIGAG 361
PP DG LC++ H DFC+KLPD+V+ EEGAL+EPLSVG++ACRRG+V+LG+KVL+ GAG
Sbjct: 165 PPDDGNLCRFYKHSADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVCGAG 224
Query: 362 TIGLVNLLVAQSLGADDIIIVDINESRLEVAKQLGANYTIQITKDSSNEYIISKIKEHIN 541
IG+V LLVA+++GA ++++D++ SRL AK++GA++TIQ+ K++ ++ I K++ +
Sbjct: 225 PIGIVTLLVAKAMGASQVVVIDLSASRLAKAKEVGADFTIQVAKETPHD-IAKKVESVLG 283
Query: 542 GLVDKTIECSGAPNAMNLAIEATVSGGCVVIVGNG 646
+ TIEC+GA +++ I AT SGG +V+VG G
Sbjct: 284 SKPEVTIECTGAESSVQDGIYATHSGGTLVVVGMG 318
Score = 66.6 bits (161), Expect = 8e-11
Identities = 30/61 (49%), Positives = 43/61 (70%)
Frame = +3
Query: 618 GGVLSLLGMGAPIVQAPLLSALIREVDIRGVFRYANCYSAALSLISQKRINVSSLVTKIF 797
GG L ++GMG ++ PL+ A +REVDI+GVFRY N + A+S+++ K +NV LVT F
Sbjct: 309 GGTLVVVGMGPEMINLPLVHAAVREVDIKGVFRYCNTWPMAVSMLASKTLNVKPLVTHRF 368
Query: 798 P 800
P
Sbjct: 369 P 369
>sp|Q64442|DHSO_MOUSE Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
Length = 375
Score = 229 bits (583), Expect = 9e-60
Identities = 113/215 (52%), Positives = 155/215 (72%)
Frame = +2
Query: 2 KSPIILGHETSAVVIKCGAKVTKLKEGDRVAIEPGVPCRRCTLCVSGRYNLCSKVVFHAT 181
K P++LGHE + V K G V LK GDRVAIEPGVP C GRYNL + F AT
Sbjct: 81 KKPMVLGHEAAGTVTKVGELVKHLKPGDRVAIEPGVpreVDEYCKIGRYNLTPTIFFCAT 140
Query: 182 PPIDGTLCQYITHPEDFCFKLPDNVSNEEGALLEPLSVGVHACRRGNVTLGSKVLIIGAG 361
PP DG LC++ H DFC+KLPD+V+ EEGAL+EPLSVG++ACRRG+V+LG+KVL+ GAG
Sbjct: 141 PPDDGNLCRFYKHNADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVCGAG 200
Query: 362 TIGLVNLLVAQSLGADDIIIVDINESRLEVAKQLGANYTIQITKDSSNEYIISKIKEHIN 541
+G+V LLVA+++GA +++ D++ SRL AK++GA++TIQ+ K++ E I SK++ +
Sbjct: 201 PVGMVTLLVAKAMGAAQVVVTDLSASRLTKAKEVGADFTIQVGKETPQE-IASKVESLLG 259
Query: 542 GLVDKTIECSGAPNAMNLAIEATVSGGCVVIVGNG 646
+ TIEC+GA +++ I AT SGG +VIVG G
Sbjct: 260 SKPEVTIECTGAESSVQTGIYATHSGGTLVIVGMG 294
Score = 70.1 bits (170), Expect = 7e-12
Identities = 33/61 (54%), Positives = 44/61 (72%)
Frame = +3
Query: 618 GGVLSLLGMGAPIVQAPLLSALIREVDIRGVFRYANCYSAALSLISQKRINVSSLVTKIF 797
GG L ++GMGA +V PL+ A IREVDI+GVFRY N + A+S+++ K +NV LVT F
Sbjct: 285 GGTLVIVGMGAEMVNLPLVHAAIREVDIKGVFRYCNTWPMAISMLASKTLNVKPLVTHRF 344
Query: 798 P 800
P
Sbjct: 345 P 345
>sp|Q00796|DHSO_HUMAN Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
Length = 357
Score = 225 bits (574), Expect = 1e-58
Identities = 113/215 (52%), Positives = 149/215 (69%)
Frame = +2
Query: 2 KSPIILGHETSAVVIKCGAKVTKLKEGDRVAIEPGVPCRRCTLCVSGRYNLCSKVVFHAT 181
K P++LGHE S V K G+ V LK GDRVAIEPG P C GRYNL + F AT
Sbjct: 63 KKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGApreNDEFCKMGRYNLSPSIFFCAT 122
Query: 182 PPIDGTLCQYITHPEDFCFKLPDNVSNEEGALLEPLSVGVHACRRGNVTLGSKVLIIGAG 361
PP DG LC++ H FC+KLPDNV+ EEGAL+EPLSVG+HACRRG VTLG KVL+ GAG
Sbjct: 123 PPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAG 182
Query: 362 TIGLVNLLVAQSLGADDIIIVDINESRLEVAKQLGANYTIQITKDSSNEYIISKIKEHIN 541
IG+V LLVA+++GA +++ D++ +RL AK++GA+ +QI+K+S E I K++ +
Sbjct: 183 PIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQE-IARKVEGLLG 241
Query: 542 GLVDKTIECSGAPNAMNLAIEATVSGGCVVIVGNG 646
+ TIEC+GA ++ I AT SGG +V+VG G
Sbjct: 242 CKPEVTIECTGAEASIQAGIYATRSGGTLVLVGLG 276
Score = 68.9 bits (167), Expect = 2e-11
Identities = 32/61 (52%), Positives = 43/61 (70%)
Frame = +3
Query: 618 GGVLSLLGMGAPIVQAPLLSALIREVDIRGVFRYANCYSAALSLISQKRINVSSLVTKIF 797
GG L L+G+G+ + PLL A IREVDI+GVFRY N + A+S+++ K +NV LVT F
Sbjct: 267 GGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRF 326
Query: 798 P 800
P
Sbjct: 327 P 327
>sp|P07846|DHSO_SHEEP Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
Length = 354
Score = 224 bits (571), Expect = 2e-58
Identities = 109/215 (50%), Positives = 151/215 (70%)
Frame = +2
Query: 2 KSPIILGHETSAVVIKCGAKVTKLKEGDRVAIEPGVPCRRCTLCVSGRYNLCSKVVFHAT 181
K P++LGHE S V+K G+ V L+ GDRVAI+PG P + C GRYNL + F AT
Sbjct: 60 KKPMVLGHEASGTVVKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCAT 119
Query: 182 PPIDGTLCQYITHPEDFCFKLPDNVSNEEGALLEPLSVGVHACRRGNVTLGSKVLIIGAG 361
PP DG LC++ H +FC+KLPDNV+ EEGAL+EPLSVG+HACRR VTLG+KVL+ GAG
Sbjct: 120 PPDDGNLCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAG 179
Query: 362 TIGLVNLLVAQSLGADDIIIVDINESRLEVAKQLGANYTIQITKDSSNEYIISKIKEHIN 541
IGLVNLL A+++GA +++ D++ SRL AK++GA++ ++I+ +S E I K++ +
Sbjct: 180 PIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEE-IAKKVEGLLG 238
Query: 542 GLVDKTIECSGAPNAMNLAIEATVSGGCVVIVGNG 646
+ TIEC+G ++ I AT SGG +V+VG G
Sbjct: 239 SKPEVTIECTGVETSIQAGIYATHSGGTLVLVGLG 273
Score = 65.9 bits (159), Expect = 1e-10
Identities = 30/61 (49%), Positives = 42/61 (68%)
Frame = +3
Query: 618 GGVLSLLGMGAPIVQAPLLSALIREVDIRGVFRYANCYSAALSLISQKRINVSSLVTKIF 797
GG L L+G+G+ + PL+ A REVDI+GVFRY N + A+S+++ K +NV LVT F
Sbjct: 264 GGTLVLVGLGSEMTSVPLVHAATREVDIKGVFRYCNTWPMAISMLASKSVNVKPLVTHRF 323
Query: 798 P 800
P
Sbjct: 324 P 324
>sp|Q02912|DHSO_BOMMO Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
Length = 348
Score = 195 bits (496), Expect = 1e-49
Identities = 90/211 (42%), Positives = 143/211 (67%)
Frame = +2
Query: 8 PIILGHETSAVVIKCGAKVTKLKEGDRVAIEPGVPCRRCTLCVSGRYNLCSKVVFHATPP 187
PI++GHE + V+K G KV+ L+ GDRVAIEP PCR C LC G+YNLC + + ++
Sbjct: 60 PIVIGHEGAGTVVKVGDKVSSLRVGDRVAIEPTQPCRSCELCKRGKYNLCVEPRYCSSMG 119
Query: 188 IDGTLCQYITHPEDFCFKLPDNVSNEEGALLEPLSVGVHACRRGNVTLGSKVLIIGAGTI 367
G LC+Y H DFC KLPDN++ EEGA ++PL++ +HAC R +TLGSK++I+GAG I
Sbjct: 120 APGNLCRYYKHVADFCHKLPDNLTMEEGAAVQPLAIVIHACNRAKITLGSKIVILGAGPI 179
Query: 368 GLVNLLVAQSLGADDIIIVDINESRLEVAKQLGANYTIQITKDSSNEYIISKIKEHINGL 547
G++ + A+++GA II+ D+ +SRL+ A +LGA+ + + ++ ++E ++ KI + +
Sbjct: 180 GILCAMSAKAMGASKIILTDVVQSRLDAALELGADNVLLVRREYTDEEVVEKIVKLLGDR 239
Query: 548 VDKTIECSGAPNAMNLAIEATVSGGCVVIVG 640
D +I+ G +A +A+ T + G V++VG
Sbjct: 240 PDVSIDACGYGSAQRVALLVTKTAGLVLVVG 270
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/65 (35%), Positives = 38/65 (58%)
Frame = +3
Query: 621 GVLSLLGMGAPIVQAPLLSALIREVDIRGVFRYANCYSAALSLISQKRINVSSLVTKIFP 800
G++ ++G+ V+ PL AL+REVD+ G FR N Y AL+ +S I + +T FP
Sbjct: 264 GLVLVVGIADKTVELPLSQALLREVDVVGSFRIMNTYQPALAAVSSGAIPLDKFITHRFP 323
Query: 801 FSDSE 815
+ ++
Sbjct: 324 LNKTK 328
>sp|P35497|DHSO1_YEAST Sorbitol dehydrogenase 1 (L-iditol 2-dehydrogenase 1)
Length = 357
Score = 192 bits (488), Expect = 9e-49
Identities = 102/224 (45%), Positives = 143/224 (63%), Gaps = 8/224 (3%)
Frame = +2
Query: 2 KSPIILGHETSAVVIKCGAKVTKLKEGDRVAIEPGVPCRRCTLCVSGRYNLCSKVVFHAT 181
K+P++LGHE+S V++ G VT++K GDRVAIEPGVP R GRYNLC + F AT
Sbjct: 61 KAPMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGRYNLCPHMAFAAT 120
Query: 182 PPIDGTLCQYITHPEDFCFKLPDNVSNEEGALLEPLSVGVHACRRGNVTLGSKVLIIGAG 361
PPIDGTL +Y PEDF KLP+ VS EEGA +EPLSVGVH+ + V G+KV++ GAG
Sbjct: 121 PPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAG 180
Query: 362 TIGLVNLLVAQSLGADDIIIVDINESRLEVAKQLGANYTIQITKDSSNEYIISKIKEHIN 541
+GL+ VA++ GA D+I VD+ +++L+ AK GA T +S+++ K ++ +
Sbjct: 181 PVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTF-----NSSQFSTDKAQDLAD 235
Query: 542 GL--------VDKTIECSGAPNAMNLAIEATVSGGCVVIVGNGR 649
G+ D ECSGA ++ A++ T GG +V VG G+
Sbjct: 236 GVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGK 279
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Frame = +3
Query: 600 LKLQFLGGVLSLLGMGAPIVQAPLLSALIREVDIRGVFRYA-NCYSAALSLISQKRINVS 776
+K +GG + +GMG P+ +E+ + G FRY+ Y A++L++ ++NV
Sbjct: 263 VKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVK 322
Query: 777 SLVTKIFPFSDS 812
L+T F F D+
Sbjct: 323 PLITHKFKFEDA 334
>sp|Q07786|DHSO2_YEAST Sorbitol dehydrogenase 2 (L-iditol 2-dehydrogenase 2)
Length = 357
Score = 190 bits (482), Expect = 5e-48
Identities = 101/224 (45%), Positives = 142/224 (63%), Gaps = 8/224 (3%)
Frame = +2
Query: 2 KSPIILGHETSAVVIKCGAKVTKLKEGDRVAIEPGVPCRRCTLCVSGRYNLCSKVVFHAT 181
K+P++LGHE+S V++ G VT++K GDRVAIEPGVP R G YNLC + F AT
Sbjct: 61 KAPMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAAT 120
Query: 182 PPIDGTLCQYITHPEDFCFKLPDNVSNEEGALLEPLSVGVHACRRGNVTLGSKVLIIGAG 361
PPIDGTL +Y PEDF KLP+ VS EEGA +EPLSVGVH+ + V G+KV++ GAG
Sbjct: 121 PPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAG 180
Query: 362 TIGLVNLLVAQSLGADDIIIVDINESRLEVAKQLGANYTIQITKDSSNEYIISKIKEHIN 541
+GL+ VA++ GA D+I VD+ +++L+ AK GA T +S+++ K ++ +
Sbjct: 181 PVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTF-----NSSQFSTDKAQDLAD 235
Query: 542 GL--------VDKTIECSGAPNAMNLAIEATVSGGCVVIVGNGR 649
G+ D ECSGA ++ A++ T GG +V VG G+
Sbjct: 236 GVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGK 279
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Frame = +3
Query: 600 LKLQFLGGVLSLLGMGAPIVQAPLLSALIREVDIRGVFRYA-NCYSAALSLISQKRINVS 776
+K +GG + +GMG P+ +E+ + G FRY+ Y A++L++ ++NV
Sbjct: 263 VKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVK 322
Query: 777 SLVTKIFPFSDS 812
L+T F F D+
Sbjct: 323 PLITHKFKFEDA 334
>sp|P36624|DHSO_SCHPO Putative sorbitol dehydrogenase (L-iditol 2-dehydrogenase) (Protein
tms1)
Length = 360
Score = 188 bits (478), Expect = 1e-47
Identities = 102/224 (45%), Positives = 138/224 (61%), Gaps = 7/224 (3%)
Frame = +2
Query: 2 KSPIILGHETSAVVIKCGAKVTKLKEGDRVAIEPGVPCRRCTLCVSGRYNLCSKVVFHAT 181
K P+ILGHE++ VV++ G V+ LK GD VA+EPG CR C C SGRYNLC + F AT
Sbjct: 60 KKPMILGHESAGVVVEVGKGVSSLKPGDPVAVEPGCVCRLCDYCRSGRYNLCPHMEFAAT 119
Query: 182 PPIDGTLCQYITHPEDFCFKLPDNVSNEEGALLEPLSVGVHACRRGNVTLGSKVLIIGAG 361
PP DGTL Y EDFC KLP +S EEGAL EP+SV VHA RGN+ GS+VL++G G
Sbjct: 120 PPYDGTLRTYYITTEDFCTKLPKQISVEEGALFEPMSVAVHAMTRGNLKCGSRVLVMGCG 179
Query: 362 TIGLVNLLVAQSLGADDIIIVDINESRLEVA-KQLGANYTIQITKDSSNEYIISKIKEHI 538
T+GL+ + VA++ GA DI+ VD + SR+E A K +GA I NE + + +
Sbjct: 180 TVGLLMMAVAKAYGAIDIVAVDASPSRVEFAQKYVGAKPFTPIAA-KENESLPDYAQRYK 238
Query: 539 NGLVDK------TIECSGAPNAMNLAIEATVSGGCVVIVGNGRP 652
+++K ++ +G ++ A+ A GG V GNG+P
Sbjct: 239 QAIIEKYGEFDFAVDATGVGICIHTAVLALKRGGTFVQAGNGKP 282
Score = 47.4 bits (111), Expect = 5e-05
Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Frame = +3
Query: 618 GGVLSLLGMGAPIVQAPLLSALIREVDIRGVFRYAN-CYSAALSLISQKRINVSSLVTKI 794
GG G G P++ P+ + E+++ G FRYA+ CY +L L+S ++V L+T
Sbjct: 271 GGTFVQAGNGKPVIDFPINHIINYEINVLGSFRYAHGCYKQSLFLVSNGLVDVKPLITHR 330
Query: 795 FPFSDS 812
F F D+
Sbjct: 331 FAFKDA 336
>sp|Q06004|DHSO_BACSU Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) (Glucitol
dehydrogenase)
Length = 353
Score = 178 bits (452), Expect = 1e-44
Identities = 95/213 (44%), Positives = 129/213 (60%)
Frame = +2
Query: 2 KSPIILGHETSAVVIKCGAKVTKLKEGDRVAIEPGVPCRRCTLCVSGRYNLCSKVVFHAT 181
+ P ILGHE + + G+ V + K GDRVA+EPGV C RC C GRYNLC V F AT
Sbjct: 63 EKPFILGHECAGEIAAVGSSVDQFKVGDRVAVEPGVTCGRCEACKEGRYNLCPDVQFLAT 122
Query: 182 PPIDGTLCQYITHPEDFCFKLPDNVSNEEGALLEPLSVGVHACRRGNVTLGSKVLIIGAG 361
PP+DG QYI +DF F +PD++S EE AL+EP SVG+HA R + GS + I+G G
Sbjct: 123 PPVDGAFVQYIKMRQDFVFLIPDSLSYEEAALIEPFSVGIHAAARTKLQPGSTIAIMGMG 182
Query: 362 TIGLVNLLVAQSLGADDIIIVDINESRLEVAKQLGANYTIQITKDSSNEYIISKIKEHIN 541
+GL+ + A++ GA II+ D+ RLE AK++GA + I I + + E I K +
Sbjct: 183 PVGLMAVAAAKAFGAGTIIVTDLEPLRLEAAKKMGATHIINIREQDALEEI--KTITNDR 240
Query: 542 GLVDKTIECSGAPNAMNLAIEATVSGGCVVIVG 640
G VD E +G P A+ A+ + GG + IVG
Sbjct: 241 G-VDVAWETAGNPAALQSALASVRRGGKLAIVG 272
Score = 35.4 bits (80), Expect = 0.19
Identities = 20/68 (29%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Frame = +3
Query: 618 GGVLSLLGMGAPIVQAPLLSALI--REVDIRGVFRYANCYSAALSLISQKRINVSSLVTK 791
GG L+++G+ + + PL I E+DI G+FRYAN Y + ++ ++ LVT
Sbjct: 265 GGKLAIVGLPSQN-EIPLNVPFIADNEIDIYGIFRYANTYPKGIEFLASGIVDTKHLVTD 323
Query: 792 IFPFSDSE 815
+ ++
Sbjct: 324 QYSLEQTQ 331
>sp|P22144|XYL2_PICST D-xylulose reductase (Xylitol dehydrogenase) (XDH)
Length = 363
Score = 177 bits (448), Expect = 4e-44
Identities = 97/219 (44%), Positives = 134/219 (61%), Gaps = 7/219 (3%)
Frame = +2
Query: 8 PIILGHETSAVVIKCGAKVTKLKEGDRVAIEPGVPCRRCTLCVSGRYNLCSKVVFHATPP 187
P++LGHE++ V++ G VT LK GD VAIEPG+P R SG YNLC + F ATP
Sbjct: 61 PMVLGHESAGTVVQVGKGVTSLKVGDNVAIEPGIPSRFSDEYKSGHYNLCPHMAFAATPN 120
Query: 188 ID-------GTLCQYITHPEDFCFKLPDNVSNEEGALLEPLSVGVHACRRGNVTLGSKVL 346
GTLC+Y PEDF KLPD+VS E GAL+EPLSVGVHA + G+V G V
Sbjct: 121 SKEGEPNPPGTLCKYFKSPEDFLVKLPDHVSLELGALVEPLSVGVHASKLGSVAFGDYVA 180
Query: 347 IIGAGTIGLVNLLVAQSLGADDIIIVDINESRLEVAKQLGANYTIQITKDSSNEYIISKI 526
+ GAG +GL+ VA++ GA +I+VDI +++L++AK +GA +K +E +I
Sbjct: 181 VFGAGPVGLLAAAVAKTFGAKGVIVVDIFDNKLKMAKDIGAATHTFNSKTGGSEELIKAF 240
Query: 527 KEHINGLVDKTIECSGAPNAMNLAIEATVSGGCVVIVGN 643
++ +V +EC+GA + L ++A GG V VGN
Sbjct: 241 GGNVPNVV---LECTGAEPCIKLGVDAIAPGGRFVQVGN 276
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,775,176
Number of Sequences: 369166
Number of extensions: 2039414
Number of successful extensions: 6604
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6017
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6336
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7811456130
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)