Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_J14
(713 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P05661|MYSA_DROME Myosin heavy chain, muscle 239 4e-63
sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscle 232 6e-61
sp|P02566|MYO4_CAEEL Myosin-4 (Myosin heavy chain B) (MHC B... 216 4e-56
sp|P12844|MYO3_CAEEL Myosin-3 (Myosin heavy chain A) (MHC A) 202 6e-52
sp|P02565|MYH3_CHICK Myosin heavy chain, fast skeletal musc... 191 1e-48
sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac muscle alp... 191 2e-48
sp|P13539|MYH6_MESAU Myosin heavy chain, cardiac muscle alp... 191 2e-48
sp|Q02566|MYH6_MOUSE Myosin heavy chain, cardiac muscle alp... 191 2e-48
sp|P02563|MYH6_RAT Myosin heavy chain, cardiac muscle alpha... 191 2e-48
sp|Q5SX40|MYH1_MOUSE Myosin-1 (Myosin heavy chain, skeletal... 189 6e-48
>sp|P05661|MYSA_DROME Myosin heavy chain, muscle
Length = 1962
Score = 239 bits (611), Expect = 4e-63
Identities = 122/200 (61%), Positives = 155/200 (77%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLD 180
SDL+E NEA+ + E+AKKA+ D++RL DE+R EQ+HAQ +K++K LE Q KELQ +LD
Sbjct: 1738 SDLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLD 1797
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
E+E NA+ EQRVRELE+ELD EQ+RH + QKN RK ERR+KE+ Q++ED+
Sbjct: 1798 EAEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDR 1857
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
KN ER+QDLV+KLQ KIKTYKRQ+EEAEEIAA+NLAK+RK QQE+E++EERAD AEQA+
Sbjct: 1858 KNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAIS 1917
Query: 541 KLRTKNRSSVSTARGGSMAP 600
K R K R+ S RG S AP
Sbjct: 1918 KFRAKGRAG-SVGRGASPAP 1936
Score = 63.2 bits (152), Expect = 7e-10
Identities = 51/209 (24%), Positives = 95/209 (45%), Gaps = 36/209 (17%)
Frame = +1
Query: 13 EASNEARQANEQAKKAVADSSR-LFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESE 189
E E +A + K +AD + L D+I + + +I+K +K+LEA+ ELQA L+E+E
Sbjct: 1488 EEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAE 1547
Query: 190 N----------NAMXXXXXXXXXXEQRVRELESE------------------LDAEQKRH 285
A ++R++E E E L+AE K
Sbjct: 1548 AALEQEENKVLRAQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGK 1607
Query: 286 VETQKNTRKIERRLKEIGLQTD-------EDKKNQERLQDLVEKLQGKIKTYKRQVEEAE 444
E + +K+E + E+ + D E +KN +R Q ++ +Q ++ +R ++A
Sbjct: 1608 AEALRMKKKLEADINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAR 1667
Query: 445 EIAAVNLAKYRKIQQEIEDSEERADQAEQ 531
E ++ + +Q E+E+S +QA++
Sbjct: 1668 EQLGISERRANALQNELEESRTLLEQADR 1696
Score = 60.8 bits (146), Expect = 3e-09
Identities = 41/178 (23%), Positives = 85/178 (47%), Gaps = 5/178 (2%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQE-----QEHAQQIDKIKKQLEAQNKELQ 168
+L+ A EA A EQ + V + ++RQE QE ++ + +K + +Q
Sbjct: 1538 ELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQ 1597
Query: 169 AKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQT 348
A L E+E E + ELE LD K + E QKN ++ +++LK+I
Sbjct: 1598 ASL-EAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQKNIKRYQQQLKDIQTAL 1656
Query: 349 DEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQ 522
+E+++ ++ ++ + + + + ++EE+ + R+ +QE+ D+ E+ ++
Sbjct: 1657 EEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQAEQELADAHEQLNE 1714
Score = 60.1 bits (144), Expect = 6e-09
Identities = 39/180 (21%), Positives = 85/180 (47%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
D+E+ ++A + L DEI + E +++K KK N++ +L
Sbjct: 952 DIEDLELNVQKAEQDKATKDHQIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQA 1011
Query: 184 SENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKK 363
+E+ + EQ + ELE L+ E+K + +K+ RK+E LK + ++
Sbjct: 1012 AEDK-INHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLER 1070
Query: 364 NQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
N++ L+ +++ ++ + ++E+ + + + + +++Q IE+ EE + QA K
Sbjct: 1071 NKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAK 1130
Score = 58.9 bits (141), Expect = 1e-08
Identities = 52/194 (26%), Positives = 93/194 (47%), Gaps = 11/194 (5%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVAD----SSRLFDEIRQEQEHAQQIDKIKKQLEA----QNKE 162
LE+ +E + E+ KK D ++ +++ QE +++ KK+LE ++KE
Sbjct: 1026 LEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKE 1085
Query: 163 LQ---AKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKE 333
L AKL E E + + R+ ELE E++AE++ + +K + R L+E
Sbjct: 1086 LSSITAKL-EDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEE 1144
Query: 334 IGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEER 513
+G + +E +L +K + ++ +R +EEA LA RK + + E
Sbjct: 1145 LGERLEEAGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRK--KHNDAVAEM 1202
Query: 514 ADQAEQALQKLRTK 555
A+Q +Q L KL+ K
Sbjct: 1203 AEQVDQ-LNKLKAK 1215
Score = 46.2 bits (108), Expect = 9e-05
Identities = 41/196 (20%), Positives = 88/196 (44%), Gaps = 5/196 (2%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHA-----QQIDKIKKQLEAQNKELQ 168
+LEE RQA +A+K AD +R +E+ + E A QI+ + K+ EA+ +L+
Sbjct: 1116 ELEEEVEAERQARAKAEKQRADLARELEELGERLEEAGGATSAQIE-LNKKREAELSKLR 1174
Query: 169 AKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQT 348
L+E+ V E+ ++D K + + + + L +
Sbjct: 1175 RDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEHDRQTCHNELNQTRTAC 1234
Query: 349 DEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAE 528
D+ +++ + + ++LQ + + +++E A +K+ E D + ++AE
Sbjct: 1235 DQLGRDKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENSDLLRQLEEAE 1294
Query: 529 QALQKLRTKNRSSVST 576
+ +L +K + S++T
Sbjct: 1295 SQVSQL-SKIKISLTT 1309
Score = 46.2 bits (108), Expect = 9e-05
Identities = 43/196 (21%), Positives = 81/196 (41%), Gaps = 15/196 (7%)
Frame = +1
Query: 13 EASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQI-------DKIKKQLEAQNKELQA 171
E + + Q N+ KA D +E+ Q + Q+ +KI KQL+ E+Q+
Sbjct: 1201 EMAEQVDQLNKLKAKAEHDRQTCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQS 1260
Query: 172 KLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTD 351
KLDE+ N + +L +L+ + + + K + +L++ D
Sbjct: 1261 KLDET-NRTLNDFDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLAD 1319
Query: 352 EDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIE--------DSE 507
E+ + + L L+ + + QVEE E A + K E + D
Sbjct: 1320 EESRERATLLGKFRNLEHDLDNLREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGV 1379
Query: 508 ERADQAEQALQKLRTK 555
R+++ E+A +KL+ +
Sbjct: 1380 ARSEELEEAKRKLQAR 1395
Score = 43.5 bits (101), Expect = 6e-04
Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 12/167 (7%)
Frame = +1
Query: 46 QAKKAVADSSRLFDEIRQEQEHAQQID-------KIKKQLEAQNKELQAKLDESENNAMX 204
Q K + + SR+ DEI + +E A++ + K++K+LEA N +L A E A+
Sbjct: 833 QKVKPLLNVSRIEDEIARLEEKAKKAEELHAAEVKVRKELEALNAKLLA-----EKTALL 887
Query: 205 XXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQ----- 369
Q +E ++L A QK +E Q R I+ RL + +ED +NQ
Sbjct: 888 DSLSGEKGALQDYQERNAKLTA-QKNDLENQ--LRDIQERLTQ-----EEDARNQLFQQK 939
Query: 370 ERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEE 510
++ + L+ I+ + V++AE+ A + R + EI +E
Sbjct: 940 KKADQEISGLKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAHQDE 986
>sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscle
Length = 1938
Score = 232 bits (592), Expect = 6e-61
Identities = 114/194 (58%), Positives = 150/194 (77%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLD 180
+DL+E E + A+E+ KKA+AD++RL DE+R EQ+H+ Q++K++K LE+Q KE Q +LD
Sbjct: 1736 TDLDEMHGELKGADERCKKAMADAARLADELRAEQDHSNQVEKVRKNLESQVKEFQIRLD 1795
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
E+E +++ E RV ELE+ELD EQ+RH ETQKN RK +RRLKE+ Q DED+
Sbjct: 1796 EAEASSLKGGKKMIQKLESRVHELEAELDNEQRRHAETQKNMRKADRRLKELAFQADEDR 1855
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
KNQERLQ+L++KL KIKT+KRQVEEAEEIAA+NLAKYRK Q E+E++EERAD A+ LQ
Sbjct: 1856 KNQERLQELIDKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAEERADTADSTLQ 1915
Query: 541 KLRTKNRSSVSTAR 582
K R K+RSSVS R
Sbjct: 1916 KFRAKSRSSVSVQR 1929
Score = 75.1 bits (183), Expect = 2e-13
Identities = 51/193 (26%), Positives = 97/193 (50%), Gaps = 10/193 (5%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQE----QEHAQQIDKIKKQLEAQNKELQAK 174
LE+A +E E+ KK D + ++ Q+ QE+ + ++++K++LE + +A+
Sbjct: 1024 LEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVEDLERVKRELEENVRRKEAE 1083
Query: 175 LD------ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEI 336
+ E E N + + R+ ELE EL+AE+ + +K ++ R L+E+
Sbjct: 1084 ISSLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEAERNARAKVEKQRAELNRELEEL 1143
Query: 337 GLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERA 516
G + DE +L +K + ++ +R +EEA ++ RK Q+ + E A
Sbjct: 1144 GERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQHEAQISALRKKHQDA--ANEMA 1201
Query: 517 DQAEQALQKLRTK 555
DQ +Q LQK+++K
Sbjct: 1202 DQVDQ-LQKVKSK 1213
Score = 71.6 bits (174), Expect = 2e-12
Identities = 47/190 (24%), Positives = 93/190 (48%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
D+ + N ++A + S L EI Q+ EH +++K KK LE NK+ L +
Sbjct: 950 DIGDLENTLQKAEQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKALEEANKKTSDSL-Q 1008
Query: 184 SENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKK 363
+E + EQ + ELE L+ E+K + +K RK+E+ LK ++ ++
Sbjct: 1009 AEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVEDLER 1068
Query: 364 NQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
+ L++ V + + +I + ++E+ + + + K +++Q IE+ EE + A K
Sbjct: 1069 VKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEAERNARAK 1128
Query: 544 LRTKNRSSVS 573
+ K R+ ++
Sbjct: 1129 VE-KQRAELN 1137
Score = 60.5 bits (145), Expect = 4e-09
Identities = 44/195 (22%), Positives = 89/195 (45%), Gaps = 9/195 (4%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDES 186
LE++ + Q + A++S L ++ + + K K QL +Q ++ + L+E
Sbjct: 1260 LEDSQRSINELQSQKSRLQAENSDLTRQLEDAEHRVSVLSKEKSQLSSQLEDARRSLEEE 1319
Query: 187 ENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTD----- 351
+ VR + +++DA +++ E Q++ ++R+L + +
Sbjct: 1320 TR--------ARSKLQNEVRNMHADMDAIREQLEEEQESKSDVQRQLSKANNEIQQWRSK 1371
Query: 352 ---EDKKNQERLQDLVEKLQGKIKTYKRQVEEAE-EIAAVNLAKYRKIQQEIEDSEERAD 519
E E L+D KL GK+ ++ E A + +A+ AK R +QQE+ED D
Sbjct: 1372 FESEGANRTEELEDQKRKLLGKLSEAEQTTEAANAKCSALEKAKSR-LQQELEDMSIEVD 1430
Query: 520 QAEQALQKLRTKNRS 564
+A ++ ++ K R+
Sbjct: 1431 RANASVNQMEKKQRA 1445
Score = 57.4 bits (137), Expect = 4e-08
Identities = 49/215 (22%), Positives = 95/215 (44%), Gaps = 37/215 (17%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLD 180
+ +EE + + K + L D++ + ++DK +++LE + +ELQA L+
Sbjct: 1483 ASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGGRSTHELDKARRRLEMEKEELQAALE 1542
Query: 181 ESEN----------NAMXXXXXXXXXXEQRVRELESE------------------LDAEQ 276
E+E A ++R++E E E L+AE
Sbjct: 1543 EAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASLEAEA 1602
Query: 277 KRHVETQKNTRKIERRLKEIGLQTD-------EDKKNQERLQDLVEKLQGKIKTYKRQVE 435
K + + +K+E+ + E+ + D E +K +R Q + ++Q I+ +RQ +
Sbjct: 1603 KGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQRQRD 1662
Query: 436 EAEEIAAVNLAKYR--KIQQEIEDSEERADQAEQA 534
EA E + N+A+ R + E+E+ +QAE+A
Sbjct: 1663 EARE--SYNMAERRCTLMSGEVEELRAALEQAERA 1695
Score = 53.9 bits (128), Expect = 4e-07
Identities = 35/186 (18%), Positives = 83/186 (44%), Gaps = 1/186 (0%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEI-RQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
LEEA Q + +A + + + +EI ++ QE ++ D ++ + + +QA L E
Sbjct: 1541 LEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKEEEFDNTRRNHQRALESMQASL-E 1599
Query: 184 SENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKK 363
+E EQ + ELE LDA + E +K ++ +++++E+ +E+++
Sbjct: 1600 AEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREMQTSIEEEQR 1659
Query: 364 NQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
++ ++ + + +VEE + E+ D+ +R ++ +
Sbjct: 1660 QRDEARESYNMAERRCTLMSGEVEELRAALEQAERARKASDNELADANDRVNELTSQVSS 1719
Query: 544 LRTKNR 561
++ + R
Sbjct: 1720 VQGQKR 1725
Score = 43.1 bits (100), Expect = 7e-04
Identities = 35/196 (17%), Positives = 85/196 (43%), Gaps = 10/196 (5%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLD 180
S LE+ N Q + K+ A L +E+ E+ +++K + +L + +EL +LD
Sbjct: 1089 SKLEDEQNLVSQLQRKIKELQARIEELEEELEAERNARAKVEKQRAELNRELEELGERLD 1148
Query: 181 ES----------ENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLK 330
E+ E+ + E+++ A +K+H + +L+
Sbjct: 1149 EAGGATSAQIELNKKREAELLKIRRDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQ 1208
Query: 331 EIGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEE 510
++ + ++DKK+ +R D L+ ++ + +E++ ++ + +EDS+
Sbjct: 1209 KVKSKLEKDKKDLKREMD---DLESQMTHNMKNKGCSEKVMKQFESQMSDLNARLEDSQR 1265
Query: 511 RADQAEQALQKLRTKN 558
++ + +L+ +N
Sbjct: 1266 SINELQSQKSRLQAEN 1281
Score = 43.1 bits (100), Expect = 7e-04
Identities = 36/190 (18%), Positives = 85/190 (44%)
Frame = +1
Query: 10 EEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESE 189
EE + R+ +++A +++ S + E + +IKK+LE EL+ LD S
Sbjct: 1577 EEEFDNTRRNHQRALESMQAS------LEAEAKGKADAMRIKKKLEQDINELEVALDAS- 1629
Query: 190 NNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQ 369
N +Q++RE+++ ++ EQ++ E +++ ERR + + +E +
Sbjct: 1630 NRGKAEMEKTVKRYQQQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAAL 1689
Query: 370 ERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLR 549
E+ + + ++ +V E + + RK++ +I + D+ L+
Sbjct: 1690 EQAERARKASDNELADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGAD 1749
Query: 550 TKNRSSVSTA 579
+ + +++ A
Sbjct: 1750 ERCKKAMADA 1759
>sp|P02566|MYO4_CAEEL Myosin-4 (Myosin heavy chain B) (MHC B) (Uncoordinated protein 54)
Length = 1966
Score = 216 bits (551), Expect = 4e-56
Identities = 106/195 (54%), Positives = 149/195 (76%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLD 180
+DL+E NE + A E++KKA+AD++RL +E+RQEQEH+Q +D+++K LE Q KE+Q +LD
Sbjct: 1751 ADLDETLNEYKAAEERSKKAIADATRLAEELRQEQEHSQHVDRLRKGLEQQLKEIQVRLD 1810
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
E+E A+ EQRVRELESELD EQ+R + KN + +RR++E+ Q DEDK
Sbjct: 1811 EAEAAALKGGKKVIAKLEQRVRELESELDGEQRRFQDANKNLGRADRRVRELQFQVDEDK 1870
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
KN ERLQDL++KLQ K+KT K+QVEEAEE+A +NL KY+++ ++ED+EERADQAE +L
Sbjct: 1871 KNFERLQDLIDKLQQKLKTQKKQVEEAEELANLNLQKYKQLTHQLEDAEERADQAENSLS 1930
Query: 541 KLRTKNRSSVSTARG 585
K+R+K+R+S S A G
Sbjct: 1931 KMRSKSRASASVAPG 1945
Score = 57.8 bits (138), Expect = 3e-08
Identities = 47/182 (25%), Positives = 81/182 (44%), Gaps = 5/182 (2%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQE-----QEHAQQIDKIKKQLEAQNKELQ 168
+L+ A +EA A E + V + +IR E QE ++ + +K + +Q
Sbjct: 1551 ELQHALDEAEAALEAEESKVLRAQVEVSQIRSEIEKRIQEKEEEFENTRKNHARALESMQ 1610
Query: 169 AKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQT 348
A L E+E E + ELE LD K + + QKN ++ + +++E+ LQ
Sbjct: 1611 ASL-ETEAKGKAELLRIKKKLEGDINELEIALDHANKANADAQKNLKRYQEQVRELQLQV 1669
Query: 349 DEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAE 528
+E+++N D E+ K E EE+ N A R +Q ++ + DQA
Sbjct: 1670 EEEQRNG---ADTREQFFNAEKRATLLQSEKEELLVANEAAERARKQAEYEAADARDQAN 1726
Query: 529 QA 534
+A
Sbjct: 1727 EA 1728
Score = 55.8 bits (133), Expect = 1e-07
Identities = 47/185 (25%), Positives = 89/185 (48%), Gaps = 9/185 (4%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
+L E R+ N+ + + D L D++ + ++ KI ++LE + +ELQ LDE
Sbjct: 1502 ELAEVVEGLRRENKSLSQEIKD---LTDQLGEGGRSVHEMQKIIRRLEIEKEELQHALDE 1558
Query: 184 SENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIE-RRLKEIGLQTDEDK 360
+E A+ + V ++ SE++ + E +NTRK R L+ + + +
Sbjct: 1559 AE-AALEAEESKVLRAQVEVSQIRSEIEKRIQEKEEEFENTRKNHARALESMQASLETEA 1617
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEI---AAVNLAKY----RKIQQEIEDSEER-A 516
K + L + +KL+G I + ++ A + A NL +Y R++Q ++E+ + A
Sbjct: 1618 KGKAELLRIKKKLEGDINELEIALDHANKANADAQKNLKRYQEQVRELQLQVEEEQRNGA 1677
Query: 517 DQAEQ 531
D EQ
Sbjct: 1678 DTREQ 1682
Score = 51.2 bits (121), Expect = 3e-06
Identities = 46/220 (20%), Positives = 88/220 (40%), Gaps = 28/220 (12%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
DL+ ++ N+ K L D + +E+ +DK K+++E + K Q +DE
Sbjct: 1021 DLQSEEDKGNHQNKVKAKLEQTLDDLEDSLEREKRARADLDKQKRKVEGELKIAQENIDE 1080
Query: 184 S-------ENNA--------------------MXXXXXXXXXXEQRVRELESELDAEQKR 282
S ENN + + R+ ELE EL+ E++
Sbjct: 1081 SGRQRHDLENNLKKKESELHSVSSRLEDEQALVSKLQRQIKDGQSRISELEEELENERQS 1140
Query: 283 HVETQKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVN 462
+ + ++R L+E+G + DE ++ +K + ++ +R +EEA
Sbjct: 1141 RSKADRAKSDLQRELEELGEKLDEQGGATAAQVEVNKKREAELAKLRRDLEEANMNHENQ 1200
Query: 463 LAKYRKIQQE-IEDSEERADQAEQALQKLRTKNRSSVSTA 579
L RK + + + ++ DQ +A K+ +V A
Sbjct: 1201 LGGLRKKHTDAVAELTDQLDQLNKAKAKVEKDKAQAVRDA 1240
Score = 47.0 bits (110), Expect = 5e-05
Identities = 40/195 (20%), Positives = 91/195 (46%), Gaps = 2/195 (1%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFD-EIRQEQEHAQQIDKIKKQLEAQNKELQAKL 177
S++E+ E + E +K A + + E + ++ +IKK+LE EL+ L
Sbjct: 1582 SEIEKRIQEKEEEFENTRKNHARALESMQASLETEAKGKAELLRIKKKLEGDINELEIAL 1641
Query: 178 DESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDED 357
D + N A +++VREL+ +++ EQ+ +T++ E+R + + +E
Sbjct: 1642 DHA-NKANADAQKNLKRYQEQVRELQLQVEEEQRNGADTREQFFNAEKRATLLQSEKEEL 1700
Query: 358 KKNQERLQDLVEKLQGKIKTYKRQVEEAE-EIAAVNLAKYRKIQQEIEDSEERADQAEQA 534
E + ++ + + + Q EA +++++ AK RK++ EI+ D+
Sbjct: 1701 LVANEAAERARKQAEYEAADARDQANEANAQVSSLTSAK-RKLEGEIQAIHADLDETLNE 1759
Query: 535 LQKLRTKNRSSVSTA 579
+ +++ +++ A
Sbjct: 1760 YKAAEERSKKAIADA 1774
Score = 32.3 bits (72), Expect = 1.3
Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 9/71 (12%)
Frame = +1
Query: 394 KLQGKIKTYKRQVEEAEEIAAVN---------LAKYRKIQQEIEDSEERADQAEQALQKL 546
KL GK+K + +EAEE+ +N LAK K+++E+E+S + + + +L
Sbjct: 843 KLYGKVKPMLKAGKEAEELEKINDKVKALEDSLAKEEKLRKELEESSAKLVEEKTSLFTN 902
Query: 547 RTKNRSSVSTA 579
++ +S A
Sbjct: 903 LESTKTQLSDA 913
>sp|P12844|MYO3_CAEEL Myosin-3 (Myosin heavy chain A) (MHC A)
Length = 1969
Score = 202 bits (515), Expect = 6e-52
Identities = 103/193 (53%), Positives = 141/193 (73%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLD 180
++LEE +NE + A EQ +KA AD++RL +E+RQEQEH+ I++I+K LE Q KE+Q +LD
Sbjct: 1752 AELEEIANELKNAVEQGQKASADAARLAEELRQEQEHSMHIERIRKGLELQIKEMQIRLD 1811
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
++EN A+ E R+R +E ELD EQ+RH +T+KN RK ERR+KE+ Q E+K
Sbjct: 1812 DAENAALKGGKKIIAQLEARIRAIEQELDGEQRRHQDTEKNWRKAERRVKEVEFQVVEEK 1871
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
KN+ERL +LV+KLQ K+K +KRQVEEAEE+AA NL KY+ + + E +EERAD AE AL
Sbjct: 1872 KNEERLTELVDKLQCKLKIFKRQVEEAEEVAASNLNKYKVLTAQFEQAEERADIAENALS 1931
Query: 541 KLRTKNRSSVSTA 579
K+R K R+S S A
Sbjct: 1932 KMRNKIRASASMA 1944
Score = 55.8 bits (133), Expect = 1e-07
Identities = 42/179 (23%), Positives = 83/179 (46%)
Frame = +1
Query: 31 RQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESENNAMXXX 210
R+A ++ + + L DE+ + E +++K KK E N++L L +SE + +
Sbjct: 975 RKAEQEKQSRDHNIRSLQDEMANQDEAVAKLNKEKKHQEESNRKLNEDL-QSEEDKVNHL 1033
Query: 211 XXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQERLQDLV 390
EQ++ ELE +D E++ + +K RK+E LK DE K + ++ +
Sbjct: 1034 EKIRNKLEQQMDELEENIDREKRSRGDIEKAKRKVEGDLKVAQENIDEITKQKHDVETTL 1093
Query: 391 EKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRTKNRSS 567
++ + + ++ E I A K+Q+ I++ R + E+ L+ R + S
Sbjct: 1094 KRKEEDLHHTNAKLAENNSIIA-------KLQRLIKELTARNAELEEELEAERNSRQKS 1145
Score = 54.3 bits (129), Expect = 3e-07
Identities = 48/212 (22%), Positives = 95/212 (44%), Gaps = 35/212 (16%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
+L E + R+ N+ + V D L D++ + ++ KI ++LE + +ELQ LDE
Sbjct: 1503 ELAEYLDSTRRENKSLAQEVKD---LTDQLGEGGRSVAELQKIVRKLEVEKEELQKALDE 1559
Query: 184 SEN----------NAMXXXXXXXXXXEQRVRELESE------------------LDAEQK 279
+E A E+R++E E E L+AE K
Sbjct: 1560 AEAALEAEEAKVLRAQIEVSQIRSEIEKRIQEKEEEFENTRRNHQRALESMQATLEAETK 1619
Query: 280 RHVETQKNTRKIERRLKEIGLQTD-------EDKKNQERLQDLVEKLQGKIKTYKRQVEE 438
+ E + +K+E + ++ + D + +K ++ + V++LQ +I+ +RQ +E
Sbjct: 1620 QKEEALRIKKKLESDINDLEIALDHANRAYADAQKTIKKYMETVQELQFQIEEEQRQKDE 1679
Query: 439 AEEIAAVNLAKYRKIQQEIEDSEERADQAEQA 534
E + + +Q E ++ ++A+ AE+A
Sbjct: 1680 IREQFLASEKRNAILQSEKDELAQQAEAAERA 1711
Score = 38.9 bits (89), Expect = 0.014
Identities = 27/108 (25%), Positives = 52/108 (48%)
Frame = +1
Query: 232 EQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGKI 411
+++ +L SELDA Q+ + + + K + E+ D ++ + L V+ L ++
Sbjct: 1470 KKKTDDLSSELDAAQRDNRQLSTDLFKAKTANDELAEYLDSTRRENKSLAQEVKDLTDQL 1529
Query: 412 KTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRTK 555
R V E ++I RK++ E E+ ++ D+AE AL+ K
Sbjct: 1530 GEGGRSVAELQKIV-------RKLEVEKEELQKALDEAEAALEAEEAK 1570
Score = 38.9 bits (89), Expect = 0.014
Identities = 36/195 (18%), Positives = 82/195 (42%), Gaps = 19/195 (9%)
Frame = +1
Query: 16 ASNEARQANEQAKKAVADSSRLFDEIRQEQEHA---------------QQIDKIKKQLEA 150
A E Q + +K + + F+ R+ + A ++ +IKK+LE+
Sbjct: 1574 AQIEVSQIRSEIEKRIQEKEEEFENTRRNHQRALESMQATLEAETKQKEEALRIKKKLES 1633
Query: 151 QNKELQAKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLK 330
+L+ LD + N A + V+EL+ +++ EQ++ E ++ E+R
Sbjct: 1634 DINDLEIALDHA-NRAYADAQKTIKKYMETVQELQFQIEEEQRQKDEIREQFLASEKRNA 1692
Query: 331 EIGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEI----E 498
+ + DE + E + + + + Q + + + RK++ E+
Sbjct: 1693 ILQSEKDELAQQAEAAERARRNAEAECIELREQNNDLNAHVSALTGQRRKLEGELLAAHA 1752
Query: 499 DSEERADQAEQALQK 543
+ EE A++ + A+++
Sbjct: 1753 ELEEIANELKNAVEQ 1767
>sp|P02565|MYH3_CHICK Myosin heavy chain, fast skeletal muscle, embryonic
Length = 1940
Score = 191 bits (486), Expect = 1e-48
Identities = 96/187 (51%), Positives = 137/187 (73%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLD 180
S++E+ EAR A E+AKKA+ D++ + +E+++EQ+ + ++++KK L+ K+LQ +LD
Sbjct: 1744 SEMEDTIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLD 1803
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
E+E A+ E RVRELE E+DAEQKR E K RK ERR+KE+ Q++ED+
Sbjct: 1804 EAEQLALKGGKKQIQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDR 1863
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
KN RLQDLV+KLQ K+K+YKRQ EEAEE++ VNL+K+RKIQ E+E++EERAD AE +
Sbjct: 1864 KNVLRLQDLVDKLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVN 1923
Query: 541 KLRTKNR 561
KLR K+R
Sbjct: 1924 KLRAKSR 1930
Score = 56.2 bits (134), Expect = 8e-08
Identities = 40/166 (24%), Positives = 85/166 (51%), Gaps = 8/166 (4%)
Frame = +1
Query: 52 KKAVADS-SRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESENNAMXXXXXXXXX 228
KKA+ ++ + D+++ E++ + K K +LE Q +L+ L++ + M
Sbjct: 1001 KKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDL------- 1053
Query: 229 XEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGK 408
E+ R+LE +L Q+ ++ + + ++++ +LK+ + + + E Q L +LQ K
Sbjct: 1054 -ERAKRKLEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKK 1112
Query: 409 IKTYKRQVE------EAEEIAAVNLAKYR-KIQQEIEDSEERADQA 525
IK + ++E EAE + K+R + +E+E+ ER ++A
Sbjct: 1113 IKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEA 1158
Score = 53.9 bits (128), Expect = 4e-07
Identities = 43/199 (21%), Positives = 90/199 (45%), Gaps = 5/199 (2%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQE-----QEHAQQIDKIKKQLEAQNKEL 165
S+L+ A EA + E + + ++++ + E ++ID++K+ +
Sbjct: 1543 SELQTALEEAEASLEHEEGKILRVQLELNQVKSDIDRKIAEKDEEIDQLKRNHLRVVDSM 1602
Query: 166 QAKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQ 345
Q+ LD +E + E + E+E +L ++ E QKN R + LK+ +
Sbjct: 1603 QSTLD-AEIRSRNEALRLKKKMEGDLNEIEIQLSHANRQAAEAQKNLRNTQGVLKDTQIH 1661
Query: 346 TDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQA 525
D+ ++QE L++ V ++ + + ++EE + +QE+ D+ ER
Sbjct: 1662 LDDALRSQEDLKEQVAMVERRANLLQAEIEELRAALEQTERSRKVAEQELLDASER---- 1717
Query: 526 EQALQKLRTKNRSSVSTAR 582
+Q L T+N S ++T +
Sbjct: 1718 ---VQLLHTQNTSLINTKK 1733
Score = 49.3 bits (116), Expect = 1e-05
Identities = 32/148 (21%), Positives = 78/148 (52%), Gaps = 2/148 (1%)
Frame = +1
Query: 115 QQIDKIKKQLEAQNKELQAKLDE--SENNAMXXXXXXXXXXEQRVRELESELDAEQKRHV 288
+ I K+ K+ +A + Q LD+ +E + + EQ+V +LE L+ E+K +
Sbjct: 992 ETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRM 1051
Query: 289 ETQKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLA 468
+ ++ RK+E LK T + + ++++L + ++K +I + ++E+ + +
Sbjct: 1052 DLERAKRKLEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGM---- 1107
Query: 469 KYRKIQQEIEDSEERADQAEQALQKLRT 552
++Q++I++ + R ++ E+ ++ RT
Sbjct: 1108 ---QLQKKIKELQARIEELEEEIEAERT 1132
Score = 47.0 bits (110), Expect = 5e-05
Identities = 38/177 (21%), Positives = 75/177 (42%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
DLEEA+ + +K ADS+ E + ++K++LE + EL+ ++D+
Sbjct: 1182 DLEEATLQHEATAAALRKKHADSTA------DVGEQIDNLQRVKQKLEKEKSELKMEIDD 1235
Query: 184 SENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKK 363
L S +++ K +K R +E +L EI + +E ++
Sbjct: 1236 ----------------------LASNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQR 1273
Query: 364 NQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQA 534
+ +LQ + Y RQVEE + + + + Q+IE+ + ++ +A
Sbjct: 1274 TINDISAQKARLQTESGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKA 1330
Score = 40.4 bits (93), Expect = 0.005
Identities = 43/200 (21%), Positives = 90/200 (45%), Gaps = 17/200 (8%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQID----KIKKQLEA-QNK---- 159
++E + A E + A +L DE + ++ ++ K++K+ A +NK
Sbjct: 924 IKELTERAEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 983
Query: 160 -ELQAKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEI 336
E A LDE+ +Q + +L++E E K + T+ T K+E+++ ++
Sbjct: 984 TEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAE---EDKVNTLTKAKT-KLEQQVDDL 1039
Query: 337 GLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRK-------IQQEI 495
+++KK + L+ KL+G +K + + E K +K IQ +I
Sbjct: 1040 EGSLEQEKKLRMDLERAKRKLEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQIQSKI 1099
Query: 496 EDSEERADQAEQALQKLRTK 555
ED + Q ++ +++L+ +
Sbjct: 1100 EDEQALGMQLQKKIKELQAR 1119
Score = 39.7 bits (91), Expect = 0.008
Identities = 45/203 (22%), Positives = 80/203 (39%), Gaps = 10/203 (4%)
Frame = +1
Query: 7 LEEASNEARQAN-----EQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQA 171
L+ A +E AN E+ K+ +A S E+ ++ Q +K QL+ Q E
Sbjct: 845 LKSAESEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVSLLQ-EKNDLQLQVQ-AEADG 902
Query: 172 KLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTD 351
D E E +++EL + E++ + E RK+E E+ D
Sbjct: 903 LADAEER--CDQLIKTKIQLEAKIKELTERAEDEEEMNAELTAKKRKLEDECSELKKDID 960
Query: 352 EDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKI-----QQEIEDSEERA 516
+ + +++ + K+K ++ +E A L K +K QQ ++D +
Sbjct: 961 DLELTLAKVEKEKHATENKVKNLTEEMAALDETIA-KLTKEKKALQEAHQQTLDDLQAEE 1019
Query: 517 DQAEQALQKLRTKNRSSVSTARG 585
D+ L K +TK V G
Sbjct: 1020 DKV-NTLTKAKTKLEQQVDDLEG 1041
Score = 33.5 bits (75), Expect = 0.58
Identities = 30/188 (15%), Positives = 73/188 (38%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDES 186
LEE + + A D L ++ +EQE ++ + + ++ + + K +
Sbjct: 1324 LEEEIKAKKCPAHALQSARHDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETD 1383
Query: 187 ENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKN 366
QR+++ E ++A + +K ++++ ++++ +
Sbjct: 1384 AIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDV------ 1437
Query: 367 QERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKL 546
ER L K K + + + E ++ KY + Q E+E S++ + L K+
Sbjct: 1438 -ERSNAACAALDKKQKNFDKILSEWKQ-------KYEETQAELEASQKESRSLSTELFKM 1489
Query: 547 RTKNRSSV 570
+ S+
Sbjct: 1490 KNAYEESL 1497
>sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha)
Length = 1939
Score = 191 bits (485), Expect = 2e-48
Identities = 97/187 (51%), Positives = 136/187 (72%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLD 180
S++EEA E R A E+AKKA+ D++ + +E+++EQ+ + ++++KK +E K+LQ +LD
Sbjct: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
E+E A+ E RVRELE EL+AEQKR+ E+ K RK ERR+KE+ QT+EDK
Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
KN RLQDLV+KLQ K+K YKRQ EEAEE A NL+K+RK+Q E++++EERAD AE +
Sbjct: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
Query: 541 KLRTKNR 561
KLR K+R
Sbjct: 1921 KLRAKSR 1927
Score = 56.2 bits (134), Expect = 8e-08
Identities = 41/166 (24%), Positives = 83/166 (50%), Gaps = 8/166 (4%)
Frame = +1
Query: 52 KKAVADS-SRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESENNAMXXXXXXXXX 228
KKA+ ++ + D+++ E++ + K K +LE Q +L+ L++ + M
Sbjct: 998 KKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDL------- 1050
Query: 229 XEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGK 408
E+ R+LE +L Q+ ++ + + ++E +LK+ ++ E Q L +LQ K
Sbjct: 1051 -ERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKK 1109
Query: 409 IKTYKRQVE------EAEEIAAVNLAKYRK-IQQEIEDSEERADQA 525
+K + ++E EAE A + K R + +E+E+ ER ++A
Sbjct: 1110 LKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEA 1155
Score = 54.7 bits (130), Expect = 2e-07
Identities = 37/182 (20%), Positives = 91/182 (50%), Gaps = 2/182 (1%)
Frame = +1
Query: 10 EEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESE 189
EE+ + K + S L +++ + ++ +++K++KQLE + ELQ+ L+E+E
Sbjct: 1491 EESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAE 1550
Query: 190 NNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQ 369
++ + ++++E++ + E + ++ +R+ + LQT D + +
Sbjct: 1551 -ASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVD-SLQTSLDAETR 1608
Query: 370 ERLQDL--VEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
R + L +K++G + + Q+ A +AA + + +Q ++D++ + D A +A
Sbjct: 1609 SRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDD 1668
Query: 544 LR 549
L+
Sbjct: 1669 LK 1670
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/186 (21%), Positives = 83/186 (44%), Gaps = 5/186 (2%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQ-----QIDKIKKQLEAQNKELQ 168
+LEE R A + +K +D SR +EI + E A QI+ KK+ EA+ ++++
Sbjct: 1119 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMR 1177
Query: 169 AKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQT 348
L+E+ V EL ++D Q+ + +K + + L ++
Sbjct: 1178 RDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1237
Query: 349 DEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAE 528
++ K + L+ + L+ + Y+ ++EEA+ + K+Q E + + ++ E
Sbjct: 1238 EQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKE 1297
Query: 529 QALQKL 546
+ +L
Sbjct: 1298 ALISQL 1303
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/115 (24%), Positives = 60/115 (52%), Gaps = 5/115 (4%)
Frame = +1
Query: 238 RVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKN--QERLQDLVE---KLQ 402
R++E + +A +K E + + E+ ++ +Q ++D N +ER L++ +L+
Sbjct: 860 RIKETLEKSEARRKELEEKMVSLLQ-EKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLE 918
Query: 403 GKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRTKNRSS 567
K+K ++E+ EE+ A AK RK++ E + ++ D E L K+ + ++
Sbjct: 919 AKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 973
Score = 39.7 bits (91), Expect = 0.008
Identities = 40/200 (20%), Positives = 81/200 (40%), Gaps = 7/200 (3%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKI--KKQLEAQNKELQAKLD 180
L+ A E A + + + E R+++ + + + K L+ Q + Q L+
Sbjct: 842 LKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLN 901
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
++E E +V+E+ L+ E++ + E RK+E E+ D+ +
Sbjct: 902 DAEERC-DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKI-----QQEIEDSEERADQA 525
+++ + K+K ++ +EI A L K +K QQ ++D + D+
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIA-KLTKEKKALQEAHQQALDDLQVEEDKV 1019
Query: 526 EQALQKLRTKNRSSVSTARG 585
+L K + K V G
Sbjct: 1020 -NSLSKSKVKLEQQVDDLEG 1038
Score = 38.1 bits (87), Expect = 0.023
Identities = 38/181 (20%), Positives = 75/181 (41%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
DLEEA+ + +K ADS + + E + ++K++LE + E + +LD+
Sbjct: 1179 DLEEATLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDD 1232
Query: 184 SENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKK 363
+N EQ + K +K +R +E + E ++ +E ++
Sbjct: 1233 VTSNM-----------EQII-----------KAKANLEKVSRTLEDQANEYRVKLEEAQR 1270
Query: 364 NQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
+ KLQ + RQ+EE E + + Q++ED + + ++ +A
Sbjct: 1271 SLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNA 1330
Query: 544 L 546
L
Sbjct: 1331 L 1331
Score = 38.1 bits (87), Expect = 0.023
Identities = 46/231 (19%), Positives = 88/231 (38%), Gaps = 43/231 (18%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQ-----------EHAQQIDKIKKQLEAQ 153
LEEA Q K ++ L ++ +++ + QQ++ +K+QLE +
Sbjct: 1265 LEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEE 1324
Query: 154 NKELQAKL------------------DESENNAMXXXXXXXXXXEQRVRELESELDAEQK 279
K A +E+E A E + E DA Q+
Sbjct: 1325 GKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1384
Query: 280 RHVETQKNTRKIERRLKE-------IGLQTDEDKKNQERLQDLVEKLQGKIK-------T 417
E ++ +K+ +RL++ + + +K + RLQ+ +E L ++
Sbjct: 1385 TE-ELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1443
Query: 418 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRTKNRSSV 570
++ ++I A KY + Q E+E S++ A L KL+ S+
Sbjct: 1444 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL 1494
Score = 35.8 bits (81), Expect = 0.12
Identities = 40/220 (18%), Positives = 89/220 (40%), Gaps = 31/220 (14%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
+L +A Q + + A + + + E+E ++ K++LE + EL+ +D+
Sbjct: 899 NLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958
Query: 184 SE-------------NNAMXXXXXXXXXXEQRVRELESELDAEQKRHVET---------- 294
E N + ++ + +L E A Q+ H +
Sbjct: 959 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDK 1018
Query: 295 ----QKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVN 462
K+ K+E+++ ++ +++KK + L+ KL+G +K + + + E
Sbjct: 1019 VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQL 1078
Query: 463 LAKYRKIQQEIEDSEERADQAEQA----LQKLRTKNRSSV 570
K +K + +I + + EQA LQK +N++ +
Sbjct: 1079 EEKLKKKEFDINQQNSKIED-EQALALQLQKKLKENQARI 1117
Score = 29.6 bits (65), Expect = 8.4
Identities = 20/120 (16%), Positives = 53/120 (44%), Gaps = 8/120 (6%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQ--------IDKIKKQLEAQNK 159
+LE ++ N ++ K + S R E+ + E ++ +DK++ +++A +
Sbjct: 1823 ELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKR 1882
Query: 160 ELQAKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIG 339
+ + +++ N + R+++ ELD ++R + K+ + ++IG
Sbjct: 1883 QAEEAEEQANTNL------------SKFRKVQHELDEAEERADIAESQVNKLRAKSRDIG 1930
>sp|P13539|MYH6_MESAU Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha)
Length = 1939
Score = 191 bits (484), Expect = 2e-48
Identities = 96/187 (51%), Positives = 137/187 (73%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLD 180
+++EEA E R A E+AKKA+ D++ + +E+++EQ+ + ++++KK +E K+LQ +LD
Sbjct: 1741 TEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
E+E A+ E RVRELE+EL+AEQKR+ E+ K RK ERR+KE+ QT+EDK
Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
KN RLQDLV+KLQ K+K YKRQ EEAEE A NL+K+RK+Q E++++EERAD AE +
Sbjct: 1861 KNLVRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
Query: 541 KLRTKNR 561
KLR K+R
Sbjct: 1921 KLRAKSR 1927
Score = 56.2 bits (134), Expect = 8e-08
Identities = 41/166 (24%), Positives = 83/166 (50%), Gaps = 8/166 (4%)
Frame = +1
Query: 52 KKAVADS-SRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESENNAMXXXXXXXXX 228
KKA+ ++ + D+++ E++ + K K +LE Q +L+ L++ + M
Sbjct: 998 KKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDL------- 1050
Query: 229 XEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGK 408
E+ R+LE +L+ Q+ ++ + + ++E +LK+ + E Q L +LQ K
Sbjct: 1051 -ERAKRKLEGDLNVTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKK 1109
Query: 409 IKTYKRQVE------EAEEIAAVNLAKYRK-IQQEIEDSEERADQA 525
+K + ++E EAE A + K R + +E+E+ ER ++A
Sbjct: 1110 LKENQARIEELEEELEAERTARAKVEKLRSDLTRELEEISERLEEA 1155
Score = 53.1 bits (126), Expect = 7e-07
Identities = 37/182 (20%), Positives = 88/182 (48%), Gaps = 2/182 (1%)
Frame = +1
Query: 10 EEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESE 189
EE+ + K + S L +++ + ++ +++K++KQLE + ELQ+ L+E+E
Sbjct: 1491 EESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKMELQSALEEAE 1550
Query: 190 NNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQ 369
++ + ++++E++ + E + ++ R+ + LQT D + +
Sbjct: 1551 -ASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVD-SLQTSLDAETR 1608
Query: 370 ERLQDL--VEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
R + L +K++G + + Q+ +A IA+ + Q ++D++ + D A A
Sbjct: 1609 SRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNAQAHLKDTQLQLDDALHANDD 1668
Query: 544 LR 549
L+
Sbjct: 1669 LK 1670
Score = 46.6 bits (109), Expect = 7e-05
Identities = 37/176 (21%), Positives = 85/176 (48%), Gaps = 2/176 (1%)
Frame = +1
Query: 31 RQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE--SENNAMX 204
+ A E K + + DEI I K+ K+ +A + Q LD+ +E + +
Sbjct: 970 KHATENKVKNLTEEMAGLDEI---------IAKLTKEKKALQEAHQQALDDLQAEEDKVN 1020
Query: 205 XXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQERLQD 384
EQ+V +LE L+ E+K ++ ++ RK+E L + + ++ +L++
Sbjct: 1021 TLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLNVTQESIMDLENDKLQLEE 1080
Query: 385 LVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRT 552
++K + I ++E+ + +A ++Q+++++++ R ++ E+ L+ RT
Sbjct: 1081 KLKKKEFDISQQNSKIEDEQALAL-------QLQKKLKENQARIEELEEELEAERT 1129
Score = 43.9 bits (102), Expect = 4e-04
Identities = 40/190 (21%), Positives = 79/190 (41%), Gaps = 2/190 (1%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKI--KKQLEAQNKELQAKLD 180
L+ A E AN + + S E R+++ + + + K L+ Q + Q L+
Sbjct: 842 LKSAETEKEMANMKEEFGRVKESLEKSEARRKELEEKMVSLLQEKNDLQFQVQAEQDNLN 901
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
++E E +V+E+ L+ E++ + E RK+E E+ D+ +
Sbjct: 902 DAEERC-DQLIKNKIQLEAKVKEMTERLEDEEEMNAELTSKKRKLEDECSELKKDIDDLE 960
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
+++ + K+K ++ +EI A L K +K QE ++ D +
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIA-KLTKEKKALQEAH--QQALDDLQAEED 1017
Query: 541 KLRTKNRSSV 570
K+ T +S V
Sbjct: 1018 KVNTLTKSKV 1027
Score = 38.9 bits (89), Expect = 0.014
Identities = 38/181 (20%), Positives = 75/181 (41%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
DLEEA+ + +K ADS + + E + ++K++LE + E + +LD+
Sbjct: 1179 DLEEATLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDD 1232
Query: 184 SENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKK 363
+N EQ + K +K +R +E + E ++ +E ++
Sbjct: 1233 VTSNM-----------EQII-----------KAKANLEKVSRTLEDQANEYRVKLEESQR 1270
Query: 364 NQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
+ KLQ + RQ+EE E + + Q++ED + + ++ +A
Sbjct: 1271 SLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNA 1330
Query: 544 L 546
L
Sbjct: 1331 L 1331
Score = 36.2 bits (82), Expect = 0.089
Identities = 45/231 (19%), Positives = 87/231 (37%), Gaps = 43/231 (18%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQ-----------EHAQQIDKIKKQLEAQ 153
LEE+ Q K ++ L ++ +++ + QQ++ +K+QLE +
Sbjct: 1265 LEESQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEE 1324
Query: 154 NKELQAKL------------------DESENNAMXXXXXXXXXXEQRVRELESELDAEQK 279
K A +E E A E + E DA Q+
Sbjct: 1325 GKAKNALAHALQSARHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1384
Query: 280 RHVETQKNTRKIERRLKE-------IGLQTDEDKKNQERLQDLVEKLQGKIK-------T 417
E ++ +K+ +RL++ + + +K + RLQ+ +E L ++
Sbjct: 1385 TE-ELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1443
Query: 418 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRTKNRSSV 570
++ ++I A KY + Q E+E S++ A L KL+ S+
Sbjct: 1444 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL 1494
Score = 34.7 bits (78), Expect = 0.26
Identities = 39/220 (17%), Positives = 88/220 (40%), Gaps = 31/220 (14%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
+L +A Q + + A + + + E+E ++ K++LE + EL+ +D+
Sbjct: 899 NLNDAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTSKKRKLEDECSELKKDIDD 958
Query: 184 SE-------------NNAMXXXXXXXXXXEQRVRELESELDAEQKRHVET---------- 294
E N + ++ + +L E A Q+ H +
Sbjct: 959 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 1018
Query: 295 ----QKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVN 462
K+ K+E+++ ++ +++KK + L+ KL+G + + + + E
Sbjct: 1019 VNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLNVTQESIMDLENDKLQL 1078
Query: 463 LAKYRKIQQEIEDSEERADQAEQA----LQKLRTKNRSSV 570
K +K + +I + + EQA LQK +N++ +
Sbjct: 1079 EEKLKKKEFDISQQNSKIED-EQALALQLQKKLKENQARI 1117
Score = 30.4 bits (67), Expect = 4.9
Identities = 20/120 (16%), Positives = 53/120 (44%), Gaps = 8/120 (6%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQ--------IDKIKKQLEAQNK 159
+LE ++ N ++ K + S R E+ + E ++ +DK++ +++A +
Sbjct: 1823 ELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKR 1882
Query: 160 ELQAKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIG 339
+ + +++ N + R+++ ELD ++R + K+ + ++IG
Sbjct: 1883 QAEEAEEQANTNL------------SKFRKVQHELDEAEERADIAESQVNKLRAKSRDIG 1930
>sp|Q02566|MYH6_MOUSE Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha)
Length = 1938
Score = 191 bits (484), Expect = 2e-48
Identities = 96/187 (51%), Positives = 137/187 (73%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLD 180
+++EEA E R A E+AKKA+ D++ + +E+++EQ+ + ++++KK +E K+LQ +LD
Sbjct: 1741 TEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
E+E A+ E RVRELE+EL+AEQKR+ E+ K RK ERR+KE+ QT+EDK
Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
KN RLQDLV+KLQ K+K YKRQ EEAEE A NL+K+RK+Q E++++EERAD AE +
Sbjct: 1861 KNLMRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
Query: 541 KLRTKNR 561
KLR K+R
Sbjct: 1921 KLRAKSR 1927
Score = 55.5 bits (132), Expect = 1e-07
Identities = 41/166 (24%), Positives = 82/166 (49%), Gaps = 8/166 (4%)
Frame = +1
Query: 52 KKAVADS-SRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESENNAMXXXXXXXXX 228
KKA+ ++ + D+++ E++ + K K +LE Q +L+ L++ + M
Sbjct: 998 KKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDL------- 1050
Query: 229 XEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGK 408
E+ R+LE +L Q+ ++ + + ++E +LK+ + E Q L +LQ K
Sbjct: 1051 -ERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKK 1109
Query: 409 IKTYKRQVE------EAEEIAAVNLAKYRK-IQQEIEDSEERADQA 525
+K + ++E EAE A + K R + +E+E+ ER ++A
Sbjct: 1110 LKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEA 1155
Score = 53.5 bits (127), Expect = 5e-07
Identities = 38/182 (20%), Positives = 88/182 (48%), Gaps = 2/182 (1%)
Frame = +1
Query: 10 EEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESE 189
EE+ + K + S L +++ + ++ +++KI+KQLE + ELQ+ L+E+E
Sbjct: 1491 EESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAE 1550
Query: 190 NNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQ 369
++ + ++++E++ + E + ++ R+ + LQT D + +
Sbjct: 1551 -ASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRMVD-SLQTSLDAETR 1608
Query: 370 ERLQDL--VEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
R + L +K++G + + Q+ +A IA+ + Q ++D++ + D A A
Sbjct: 1609 SRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDD 1668
Query: 544 LR 549
L+
Sbjct: 1669 LK 1670
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/186 (21%), Positives = 83/186 (44%), Gaps = 5/186 (2%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQ-----QIDKIKKQLEAQNKELQ 168
+LEE R A + +K +D SR +EI + E A QI+ KK+ EA+ ++++
Sbjct: 1119 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMR 1177
Query: 169 AKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQT 348
L+E+ V EL ++D Q+ + +K + + L ++
Sbjct: 1178 RDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1237
Query: 349 DEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAE 528
++ K + L+ + L+ + Y+ ++EEA+ + K+Q E + + ++ E
Sbjct: 1238 EQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKE 1297
Query: 529 QALQKL 546
+ +L
Sbjct: 1298 ALISQL 1303
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/190 (20%), Positives = 79/190 (41%), Gaps = 2/190 (1%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKI--KKQLEAQNKELQAKLD 180
L+ A E AN + + + E R+++ + + + K L+ Q + Q L+
Sbjct: 842 LKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLN 901
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
++E E +V+E+ L+ E++ + E RK+E E+ D+ +
Sbjct: 902 DAEERC-DQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
+++ + K+K ++ +EI A L K +K QE ++ D +
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIA-KLTKEKKALQEAH--QQALDDLQAEED 1017
Query: 541 KLRTKNRSSV 570
K+ T +S V
Sbjct: 1018 KVNTLTKSKV 1027
Score = 38.9 bits (89), Expect = 0.014
Identities = 40/188 (21%), Positives = 78/188 (41%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
DLEEA+ + +K ADS + + E + ++K++LE + E + +LD+
Sbjct: 1179 DLEEATLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDD 1232
Query: 184 SENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKK 363
+N EQ + K +K +R +E + E ++ +E ++
Sbjct: 1233 VTSNM-----------EQII-----------KAKANLEKVSRTLEDQANEYRVKLEEAQR 1270
Query: 364 NQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
+ KLQ + RQ+EE E + + Q++ED + + ++ +A
Sbjct: 1271 SLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNA 1330
Query: 544 LRTKNRSS 567
L +SS
Sbjct: 1331 LAHALQSS 1338
Score = 37.4 bits (85), Expect = 0.040
Identities = 46/231 (19%), Positives = 87/231 (37%), Gaps = 43/231 (18%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQ-----------EHAQQIDKIKKQLEAQ 153
LEEA Q K ++ L ++ +++ + QQ++ +K+QLE +
Sbjct: 1265 LEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEE 1324
Query: 154 NKELQAKL------------------DESENNAMXXXXXXXXXXEQRVRELESELDAEQK 279
K A +E E A E + E DA Q+
Sbjct: 1325 GKAKNALAHALQSSRHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1384
Query: 280 RHVETQKNTRKIERRLKE-------IGLQTDEDKKNQERLQDLVEKLQGKIK-------T 417
E ++ +K+ +RL++ + + +K + RLQ+ +E L ++
Sbjct: 1385 TE-ELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1443
Query: 418 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRTKNRSSV 570
++ ++I A KY + Q E+E S++ A L KL+ S+
Sbjct: 1444 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL 1494
Score = 35.8 bits (81), Expect = 0.12
Identities = 40/220 (18%), Positives = 89/220 (40%), Gaps = 31/220 (14%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
+L +A Q + + A + + + E+E ++ K++LE + EL+ +D+
Sbjct: 899 NLNDAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958
Query: 184 SE-------------NNAMXXXXXXXXXXEQRVRELESELDAEQKRHVET---------- 294
E N + ++ + +L E A Q+ H +
Sbjct: 959 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 1018
Query: 295 ----QKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVN 462
K+ K+E+++ ++ +++KK + L+ KL+G +K + + + E
Sbjct: 1019 VNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQL 1078
Query: 463 LAKYRKIQQEIEDSEERADQAEQA----LQKLRTKNRSSV 570
K +K + +I + + EQA LQK +N++ +
Sbjct: 1079 EEKLKKKEFDISQQNSKIED-EQALALQLQKKLKENQARI 1117
Score = 32.0 bits (71), Expect = 1.7
Identities = 21/128 (16%), Positives = 57/128 (44%), Gaps = 8/128 (6%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQ--------IDKIKKQLEAQNK 159
+LE ++ N ++ K + S R E+ + E ++ +DK++ +++A +
Sbjct: 1823 ELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQLKVKAYKR 1882
Query: 160 ELQAKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIG 339
+ + +++ N + R+++ ELD ++R + K+ + ++IG
Sbjct: 1883 QAEEAEEQANTNL------------SKFRKVQHELDEAEERADIAESQVNKLRAKSRDIG 1930
Query: 340 LQTDEDKK 363
+ D++
Sbjct: 1931 AKKMHDEE 1938
>sp|P02563|MYH6_RAT Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha)
Length = 1938
Score = 191 bits (484), Expect = 2e-48
Identities = 96/187 (51%), Positives = 137/187 (73%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLD 180
+++EEA E R A E+AKKA+ D++ + +E+++EQ+ + ++++KK +E K+LQ +LD
Sbjct: 1740 TEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1799
Query: 181 ESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
E+E A+ E RVRELE+EL+AEQKR+ E+ K RK ERR+KE+ QT+EDK
Sbjct: 1800 EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1859
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
KN RLQDLV+KLQ K+K YKRQ EEAEE A NL+K+RK+Q E++++EERAD AE +
Sbjct: 1860 KNLVRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1919
Query: 541 KLRTKNR 561
KLR K+R
Sbjct: 1920 KLRAKSR 1926
Score = 55.1 bits (131), Expect = 2e-07
Identities = 41/166 (24%), Positives = 82/166 (49%), Gaps = 8/166 (4%)
Frame = +1
Query: 52 KKAVADS-SRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESENNAMXXXXXXXXX 228
KKA+ ++ + D+++ E++ + K K +LE Q +L+ L++ + M
Sbjct: 997 KKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDL------- 1049
Query: 229 XEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGK 408
E+ R+LE +L Q+ ++ + + ++E +LK+ + E Q L +LQ K
Sbjct: 1050 -ERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKK 1108
Query: 409 IKTYKRQVE------EAEEIAAVNLAKYRK-IQQEIEDSEERADQA 525
+K + ++E EAE A + K R + +E+E+ ER ++A
Sbjct: 1109 LKENQARIEELEEELEAERTARAKVEKLRSDLTRELEEISERLEEA 1154
Score = 53.9 bits (128), Expect = 4e-07
Identities = 38/182 (20%), Positives = 89/182 (48%), Gaps = 2/182 (1%)
Frame = +1
Query: 10 EEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESE 189
EE+ + K + S L +++ + ++ +++KI+KQLE + ELQ+ L+E+E
Sbjct: 1490 EESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAE 1549
Query: 190 NNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQ 369
++ + ++++E++ + E + ++ R+ + LQT D + +
Sbjct: 1550 -ASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVD-SLQTSLDAETR 1607
Query: 370 ERLQDL--VEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
R + L +K++G + + Q+ +A IA+ + Q ++D++ + D A +A
Sbjct: 1608 SRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNAQAHLKDTQLQLDDAVRANDD 1667
Query: 544 LR 549
L+
Sbjct: 1668 LK 1669
Score = 43.9 bits (102), Expect = 4e-04
Identities = 39/186 (20%), Positives = 83/186 (44%), Gaps = 5/186 (2%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQ-----QIDKIKKQLEAQNKELQ 168
+LEE R A + +K +D +R +EI + E A QI+ KK+ EA+ ++++
Sbjct: 1118 ELEEELEAERTARAKVEKLRSDLTRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMR 1176
Query: 169 AKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQT 348
L+E+ V EL ++D Q+ + +K + + L ++
Sbjct: 1177 RDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSHM 1236
Query: 349 DEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAE 528
++ K + L+ + L+ + Y+ ++EEA+ + K+Q E + + ++ E
Sbjct: 1237 EQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKE 1296
Query: 529 QALQKL 546
+ +L
Sbjct: 1297 ALIWQL 1302
Score = 42.7 bits (99), Expect = 0.001
Identities = 37/194 (19%), Positives = 80/194 (41%), Gaps = 6/194 (3%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDES 186
L+ A E AN + + R+ D + + + +++++ L + +LQ ++
Sbjct: 841 LKSAETEKEMANMKE-----EFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 895
Query: 187 ENNAMXXXXXXXXXX------EQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQT 348
++N E +V+E+ L+ E++ + E RK+E E+
Sbjct: 896 QDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDI 955
Query: 349 DEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAE 528
D+ + +++ + K+K ++ +EI A L K +K QE ++ D +
Sbjct: 956 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIA-KLTKEKKALQEAH--QQALDDLQ 1012
Query: 529 QALQKLRTKNRSSV 570
K+ T +S V
Sbjct: 1013 AEEDKVNTLTKSKV 1026
Score = 37.4 bits (85), Expect = 0.040
Identities = 46/231 (19%), Positives = 87/231 (37%), Gaps = 43/231 (18%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQ-----------EHAQQIDKIKKQLEAQ 153
LEEA Q K ++ L ++ +++ + QQ++ +K+QLE +
Sbjct: 1264 LEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALIWQLTRGKLSYTQQMEDLKRQLEEE 1323
Query: 154 NKELQAKL------------------DESENNAMXXXXXXXXXXEQRVRELESELDAEQK 279
K A +E E A E + E DA Q+
Sbjct: 1324 GKAKNALAHALQSARHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1383
Query: 280 RHVETQKNTRKIERRLKE-------IGLQTDEDKKNQERLQDLVEKLQGKIK-------T 417
E ++ +K+ +RL++ + + +K + RLQ+ +E L ++
Sbjct: 1384 TE-ELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1442
Query: 418 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRTKNRSSV 570
++ ++I A KY + Q E+E S++ A L KL+ S+
Sbjct: 1443 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL 1493
Score = 35.4 bits (80), Expect = 0.15
Identities = 40/220 (18%), Positives = 89/220 (40%), Gaps = 31/220 (14%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
+L +A Q + + A + + + E+E ++ K++LE + EL+ +D+
Sbjct: 898 NLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDD 957
Query: 184 SE-------------NNAMXXXXXXXXXXEQRVRELESELDAEQKRHVET---------- 294
E N + ++ + +L E A Q+ H +
Sbjct: 958 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 1017
Query: 295 ----QKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVN 462
K+ K+E+++ ++ +++KK + L+ KL+G +K + + + E
Sbjct: 1018 VNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQL 1077
Query: 463 LAKYRKIQQEIEDSEERADQAEQA----LQKLRTKNRSSV 570
K +K + +I + + EQA LQK +N++ +
Sbjct: 1078 EEKLKKKEFDISQQNSKIED-EQALALQLQKKLKENQARI 1116
Score = 30.4 bits (67), Expect = 4.9
Identities = 20/120 (16%), Positives = 53/120 (44%), Gaps = 8/120 (6%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQ--------IDKIKKQLEAQNK 159
+LE ++ N ++ K + S R E+ + E ++ +DK++ +++A +
Sbjct: 1822 ELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKR 1881
Query: 160 ELQAKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIG 339
+ + +++ N + R+++ ELD ++R + K+ + ++IG
Sbjct: 1882 QAEEAEEQANTNL------------SKFRKVQHELDEAEERADIAESQVNKLRAKSRDIG 1929
>sp|Q5SX40|MYH1_MOUSE Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1)
Length = 1942
Score = 189 bits (480), Expect = 6e-48
Identities = 97/186 (52%), Positives = 135/186 (72%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDE 183
++E+ EAR A E+AKKA+ D++ + +E+++EQ+ + ++++KK LE K+LQ +LDE
Sbjct: 1747 EMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1806
Query: 184 SENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKK 363
+E A+ E RVRELE E++ EQKR+VE K RK ERR+KE+ QT+ED+K
Sbjct: 1807 AEQLALKGGKKQIQKLEARVRELEGEVENEQKRNVEAIKGLRKHERRVKELTYQTEEDRK 1866
Query: 364 NQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
N RLQDLV+KLQ K+K YKRQ EEAEE + VNLAK+RKIQ E+E++EERAD AE + K
Sbjct: 1867 NVLRLQDLVDKLQSKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNK 1926
Query: 544 LRTKNR 561
LR K+R
Sbjct: 1927 LRVKSR 1932
Score = 58.2 bits (139), Expect = 2e-08
Identities = 42/183 (22%), Positives = 90/183 (49%), Gaps = 3/183 (1%)
Frame = +1
Query: 10 EEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESE 189
EE+ + + K + S L ++I + + +++KIKKQ+E + ELQA L+E+E
Sbjct: 1496 EESLDHLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQIEQEKSELQAALEEAE 1555
Query: 190 NNAMXXXXXXXXXXEQRVRELESELD---AEQKRHVETQKNTRKIERRLKEIGLQTDEDK 360
++ + + +++SE+D AE+ ++ K R R ++ + D +
Sbjct: 1556 -ASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLK--RNHIRVVESMQSTLDAEI 1612
Query: 361 KNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQ 540
+++ L +K++G + + Q+ + +AA L YR Q ++D++ D A + +
Sbjct: 1613 RSRNDAIRLKKKMEGDLNEMEIQLNHSNRMAAEALRNYRNTQGILKDTQLHLDDALRGQE 1672
Query: 541 KLR 549
L+
Sbjct: 1673 DLK 1675
Score = 55.5 bits (132), Expect = 1e-07
Identities = 37/165 (22%), Positives = 81/165 (49%), Gaps = 1/165 (0%)
Frame = +1
Query: 52 KKAVADS-SRLFDEIRQEQEHAQQIDKIKKQLEAQNKELQAKLDESENNAMXXXXXXXXX 228
KKA+ ++ + D+++ E++ + K K +LE Q +L+ L++ + M
Sbjct: 1003 KKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDL------- 1055
Query: 229 XEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQTDEDKKNQERLQDLVEKLQGK 408
E+ R+LE +L Q+ ++ + + ++++ +LK+ + + E Q L +LQ K
Sbjct: 1056 -ERAKRKLEGDLKLAQESTMDVENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKK 1114
Query: 409 IKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQK 543
IK + ++EE EE A K +++ D ++ + L++
Sbjct: 1115 IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1159
Score = 50.4 bits (119), Expect = 5e-06
Identities = 42/199 (21%), Positives = 89/199 (44%), Gaps = 5/199 (2%)
Frame = +1
Query: 1 SDLEEASNEARQANEQAKKAVADSSRLFDEIRQE-----QEHAQQIDKIKKQLEAQNKEL 165
S+L+ A EA + E + + ++++ E E ++ID++K+ + +
Sbjct: 1545 SELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHIRVVESM 1604
Query: 166 QAKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIERRLKEIGLQ 345
Q+ LD +E + E + E+E +L+ + E +N R + LK+ L
Sbjct: 1605 QSTLD-AEIRSRNDAIRLKKKMEGDLNEMEIQLNHSNRMAAEALRNYRNTQGILKDTQLH 1663
Query: 346 TDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQA 525
D+ + QE L++ + ++ + + ++EE + +QE+ D+ ER
Sbjct: 1664 LDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASER---- 1719
Query: 526 EQALQKLRTKNRSSVSTAR 582
+Q L T+N S ++T +
Sbjct: 1720 ---VQLLHTQNTSLINTKK 1735
Score = 39.3 bits (90), Expect = 0.011
Identities = 26/126 (20%), Positives = 60/126 (47%), Gaps = 14/126 (11%)
Frame = +1
Query: 232 EQRVRELESELDAEQKRHVETQKNTRKIERRL-------KEIGLQTDEDKKN----QERL 378
E+ + ++ E + ++ + + +++E ++ ++ LQ + + +ER
Sbjct: 853 EKEMANMKEEFEKAKENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEERC 912
Query: 379 QDLVE---KLQGKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLR 549
L++ +L+ KIK + E+ EEI A AK RK++ E + ++ D E L K+
Sbjct: 913 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 972
Query: 550 TKNRSS 567
+ ++
Sbjct: 973 KEKHAT 978
Score = 37.4 bits (85), Expect = 0.040
Identities = 39/224 (17%), Positives = 94/224 (41%), Gaps = 41/224 (18%)
Frame = +1
Query: 7 LEEASNEARQANEQAKKAVADSSRLFDEIRQEQEHAQQIDKI-------KKQLEAQNKEL 165
++ ++ A E+ + + +L +I++ E A+ ++I K++LE + EL
Sbjct: 898 VQSEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSEL 957
Query: 166 QAKLDESE-------------NNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNT 306
+ +D+ E N + ++ + +L E A Q+ H +T +
Sbjct: 958 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDL 1017
Query: 307 R--------------KIERRLKEIGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAE 444
+ K+E+++ ++ +++KK + L+ KL+G +K + + E
Sbjct: 1018 QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDVE 1077
Query: 445 EIAAVNLAKYRK-------IQQEIEDSEERADQAEQALQKLRTK 555
K +K +Q +IED + Q ++ +++L+ +
Sbjct: 1078 NDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQAR 1121
Score = 37.4 bits (85), Expect = 0.040
Identities = 45/215 (20%), Positives = 95/215 (44%), Gaps = 35/215 (16%)
Frame = +1
Query: 4 DLEEASNEARQANEQAKKAVAD-----------SSRLFDEIRQEQEHAQQIDKIKKQ--- 141
DL E + +N A +A+ + L D +R +++ +Q+ ++++
Sbjct: 1628 DLNEMEIQLNHSNRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANL 1687
Query: 142 LEAQNKELQAKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQKRHVETQKNTRKIER 321
L+A+ +EL+A L+++E + +++ E E LDA ++ + +NT I
Sbjct: 1688 LQAEIEELRATLEQTERS-------------RKIAEQEL-LDASERVQLLHTQNTSLINT 1733
Query: 322 RLKEIGLQTDEDKKNQERLQDLVEKLQGKIKTYKRQVEEAEEIA---------------- 453
+ K L+TD + ++QG+++ ++ AEE A
Sbjct: 1734 KKK---LETD------------ISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKK 1778
Query: 454 ----AVNLAKYRK-IQQEIEDSEERADQAEQALQK 543
+ +L + +K ++Q ++D + R D+AEQ K
Sbjct: 1779 EQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALK 1813
Score = 33.1 bits (74), Expect = 0.76
Identities = 39/210 (18%), Positives = 86/210 (40%), Gaps = 31/210 (14%)
Frame = +1
Query: 34 QANEQAKKAVADSSRLFDEIRQEQEHAQQIDKIKKQLEAQNK----------------EL 165
++ E +++ S + R +Q QQI+++K+QLE + K +L
Sbjct: 1290 ESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDL 1349
Query: 166 QAKLDESENNAMXXXXXXXXXXEQRVRELESELDAEQ-KRHVETQKNTRKIERRLKE--- 333
+ E E A V + ++ + + +R E ++ +K+ +RL++
Sbjct: 1350 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1409
Query: 334 ----IGLQTDEDKKNQERLQDLVEKLQGKIK-------TYKRQVEEAEEIAAVNLAKYRK 480
+ + +K ++RLQ+ VE L ++ ++ ++I A KY +
Sbjct: 1410 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKYEE 1469
Query: 481 IQQEIEDSEERADQAEQALQKLRTKNRSSV 570
E+E S++ + L K++ S+
Sbjct: 1470 THAELEASQKESRSLSTELFKIKNAYEESL 1499
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.309 0.125 0.313
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,446,981
Number of Sequences: 369166
Number of extensions: 1051507
Number of successful extensions: 7991
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5739
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7240
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6316483550
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)