Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_J02
(505 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O95858|TSN15_HUMAN Tetraspanin-15 (Tspan-15) (Transmembr... 38 0.016
sp|Q9UKR8|TNS16_HUMAN Tetraspanin-16 (Tspan-16) (Transmembr... 37 0.035
sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated anti... 36 0.045
sp|Q8NG11|TSN14_HUMAN Tetraspanin-14 (Tspan-14) (Transmembr... 35 0.078
sp|Q8QZY6|TSN14_MOUSE Tetraspanin-14 (Tspan-14) (Transmembr... 35 0.13
sp|Q9D7W4|TSN17_MOUSE Tetraspanin-17 (Tspan-17) (Transmembr... 34 0.17
sp|P62080|TSN5_MOUSE Tetraspanin-5 (Tspan-5) (Transmembrane... 34 0.23
sp|Q68VK5|TSN5_RAT Tetraspanin-5 (Tspan-5) (Transmembrane 4... 34 0.23
sp|Q96FV3|TSN17_HUMAN Tetraspanin-17 (Tspan-17) (Transmembr... 33 0.29
sp|Q28709|CD63_RABIT CD63 antigen 33 0.29
>sp|O95858|TSN15_HUMAN Tetraspanin-15 (Tspan-15) (Transmembrane 4 superfamily member 15)
(Tetraspan NET-7)
Length = 294
Score = 37.7 bits (86), Expect = 0.016
Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Frame = +3
Query: 60 LDVSGIIDLIQAKFKCCGASSSADFVANTGYNKSYG-----IIPFSCCMMVGQTLTPADS 224
LD I+D +Q KFKCCG D+ N ++ S +P++CC+ + T +
Sbjct: 139 LDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCI---RNTTEVVN 195
Query: 225 NCTYYPTVNNSYFN 266
Y T++ F+
Sbjct: 196 TMCGYKTIDKERFS 209
>sp|Q9UKR8|TNS16_HUMAN Tetraspanin-16 (Tspan-16) (Transmembrane 4 superfamily member 16)
(Tetraspanin TM4-B)
Length = 245
Score = 36.6 bits (83), Expect = 0.035
Identities = 22/83 (26%), Positives = 34/83 (40%)
Frame = +3
Query: 63 DVSGIIDLIQAKFKCCGASSSADFVANTGYNKSYGIIPFSCCMMVGQTLTPADSNCTYYP 242
D S +L+ K KCCG ++ DF ++ + P SCC +G +C
Sbjct: 139 DYSTQWNLVMEKLKCCGVNNYTDFSGSSFEMTTGHTYPRSCCKSIGSV------SCDGRD 192
Query: 243 TVNNSYFNTGCYSQLWNIINSYS 311
N GC+ +L I + S
Sbjct: 193 VSPNVIHQKGCFHKLLKITKTQS 215
>sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated antigen ME491)
(Lysosome-associated membrane glycoprotein 3) (LAMP-3)
(Ocular melanoma-associated antigen) (OMA81H)
(Granulophysin) (Tetraspanin-30) (Tspan-30)
Length = 238
Score = 36.2 bits (82), Expect = 0.045
Identities = 17/43 (39%), Positives = 27/43 (62%)
Frame = +3
Query: 69 SGIIDLIQAKFKCCGASSSADFVANTGYNKSYGIIPFSCCMMV 197
+ I+D +QA FKCCGA++ D+ +K+ +P SCC+ V
Sbjct: 133 ASILDRMQADFKCCGAANYTDWEKIPSMSKNR--VPDSCCINV 173
>sp|Q8NG11|TSN14_HUMAN Tetraspanin-14 (Tspan-14) (Transmembrane 4 superfamily member 14)
(DC-TM4F2)
Length = 270
Score = 35.4 bits (80), Expect = 0.078
Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 12/88 (13%)
Frame = +3
Query: 60 LDVSGIIDLIQAKFKCCGASSSADFVANTGYNKSYGI-------IPFSCCM-----MVGQ 203
+D+ +ID +Q +CCGA D+ N +N S +PFSCC+ V
Sbjct: 138 IDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVN 197
Query: 204 TLTPADSNCTYYPTVNNSYFNTGCYSQL 287
T D + S F GC L
Sbjct: 198 TQCGYDVRIQLKSKWDESIFTKGCIQAL 225
>sp|Q8QZY6|TSN14_MOUSE Tetraspanin-14 (Tspan-14) (Transmembrane 4 superfamily member 14)
Length = 270
Score = 34.7 bits (78), Expect = 0.13
Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 7/51 (13%)
Frame = +3
Query: 60 LDVSGIIDLIQAKFKCCGASSSADFVANTGYNKSYGI-------IPFSCCM 191
+D+ +ID +Q +CCGA D+ N +N S +PFSCC+
Sbjct: 138 IDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCV 188
>sp|Q9D7W4|TSN17_MOUSE Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17)
(Tetraspan protein SB134) (F-box only protein 23)
Length = 270
Score = 34.3 bits (77), Expect = 0.17
Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 7/51 (13%)
Frame = +3
Query: 60 LDVSGIIDLIQAKFKCCGASSSADFVANTGYN-------KSYGIIPFSCCM 191
LD+ +ID Q + CCGA D+ N +N + +PFSCC+
Sbjct: 140 LDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCV 190
>sp|P62080|TSN5_MOUSE Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9)
(Tetraspan NET-4)
sp|P62079|TSN5_HUMAN Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9)
(Tetraspan NET-4)
Length = 268
Score = 33.9 bits (76), Expect = 0.23
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 7/50 (14%)
Frame = +3
Query: 60 LDVSGIIDLIQAKFKCCGASSSADFVANTGYN-------KSYGIIPFSCC 188
+D+ +ID Q ++CCGA + D+ N +N + +PFSCC
Sbjct: 138 IDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCC 187
>sp|Q68VK5|TSN5_RAT Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9)
Length = 268
Score = 33.9 bits (76), Expect = 0.23
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 7/50 (14%)
Frame = +3
Query: 60 LDVSGIIDLIQAKFKCCGASSSADFVANTGYN-------KSYGIIPFSCC 188
+D+ +ID Q ++CCGA + D+ N +N + +PFSCC
Sbjct: 138 IDLQSLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCC 187
>sp|Q96FV3|TSN17_HUMAN Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17)
(Tetraspan protein SB134) (F-box only protein 23)
Length = 263
Score = 33.5 bits (75), Expect = 0.29
Identities = 16/51 (31%), Positives = 25/51 (49%), Gaps = 7/51 (13%)
Frame = +3
Query: 60 LDVSGIIDLIQAKFKCCGASSSADFVANTGYN-------KSYGIIPFSCCM 191
+D+ +ID Q + CCGA D+ N +N + +PFSCC+
Sbjct: 140 IDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCV 190
>sp|Q28709|CD63_RABIT CD63 antigen
Length = 238
Score = 33.5 bits (75), Expect = 0.29
Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Frame = +3
Query: 24 FNKT---QRSTGSSGLDVSGIIDLIQAKFKCCGASSSADFVANTGYNKSYGIIPFSCCMM 194
FNK Q S+ + I+D +Q F CCGA++ D+ G + +P SCC+
Sbjct: 115 FNKDFRQQMQNYSTDNQTALILDRMQKDFTCCGAANYTDWATIPGMTRDR--VPDSCCVN 172
Query: 195 V 197
V
Sbjct: 173 V 173
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,044,716
Number of Sequences: 369166
Number of extensions: 964770
Number of successful extensions: 2083
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2060
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2081
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3218280650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)