Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_I14
(898 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P54677|PI4K_DICDI Phosphatidylinositol 4-kinase (PI4-kin... 40 0.012
sp|P54637|PTP3_DICDI Tyrosine-protein phosphatase 3 (Protei... 34 0.63
sp|Q9UTJ8|RAD50_SCHPO DNA repair protein rad50 33 0.83
sp|Q20845|PLK3_CAEEL Serine/threonine-protein kinase plk-3 ... 33 1.1
sp|Q5UIP0|RIF1_HUMAN Telomere-associated protein RIF1 (Rap1... 33 1.1
sp|P09547|SWI1_YEAST Transcription regulatory protein SWI1 ... 33 1.4
sp|Q06168|SFH1_YEAST Chromatin structure remodeling complex... 33 1.4
sp|Q9NFU0|FXR1_DROME Fragile X mental retardation syndrome-... 32 2.4
sp|Q5FIN5|SYS_LACAC Seryl-tRNA synthetase (Serine--tRNA lig... 32 2.4
sp|Q9ZK27|SYH_HELPJ Histidyl-tRNA synthetase (Histidine--tR... 32 2.4
>sp|P54677|PI4K_DICDI Phosphatidylinositol 4-kinase (PI4-kinase) (PtdIns-4-kinase)
(PI4K-alpha)
Length = 1093
Score = 39.7 bits (91), Expect = 0.012
Identities = 46/231 (19%), Positives = 94/231 (40%), Gaps = 5/231 (2%)
Frame = +1
Query: 211 LPKELEMLYEL--YSDDDITMTNNIKIGLLDIDKDLYNYERNLPVEIDSSSDIR---DMT 375
+P +L+ +Y Y DDD ++++ G I K ++YE + +E D DI +
Sbjct: 132 VPIDLDKIYNQSQYDDDDFDLSDDDG-GFEIIKKKCHHYENDHHIENDPKKDINSNNNNN 190
Query: 376 SNVSVNEVREEDESLASLPLIHNPHATPESWDNDSLRQAHKKSSFNSFFQTNFDTKYNAG 555
+N++ N +D + + P+ ++ ND Q ++ N+ N + K +
Sbjct: 191 NNINNNNSNNDDNNNNEIL----PNENSDNSINDENNQYGNSNNNNNISGENNNIKIDIN 246
Query: 556 PKPAFESVSNTNRNFMMSKPPINQLPYRTTNKSILPDLRGRQLVGPIEKKNNSRSRSFEP 735
++ S++N T N ++ + + + +E NN+ + +
Sbjct: 247 S----QNKSDSN--------------IETLNSTLCEETKTSPIKDDMENNNNNNNNN--- 285
Query: 736 EPDTSRNNGNSTTLNNRYANSNVRKLVVGPRLDPFGNTIYDLDLRGKKYIS 888
+ + NN N+ +NN N+N ++ LD G+ YIS
Sbjct: 286 -NNNNNNNNNNNNINNNNINNNNINNNNNINYGHINGSLSTLDGIGQPYIS 335
>sp|P54637|PTP3_DICDI Tyrosine-protein phosphatase 3 (Protein-tyrosine-phosphate
phosphohydrolase 3)
Length = 989
Score = 33.9 bits (76), Expect = 0.63
Identities = 31/165 (18%), Positives = 59/165 (35%), Gaps = 3/165 (1%)
Frame = +1
Query: 319 YERNLPVEIDSSSDIRDMTSNVSVNEVREEDESLASLPLIHNPHATPESWDNDSLRQAHK 498
Y N P I S S+ N + N + ++ + N + TP+S + +
Sbjct: 38 YANNTPEMIQSQSE------NTNTNNINNSSSNINN-----NNNNTPDSMSMSTSLSSSP 86
Query: 499 KSSFNSFFQTNFDTKYNAGPKPAFESVSNTNRNFMMSKPPI---NQLPYRTTNKSILPDL 669
SFN + + K N + +N N + + N + + N + +
Sbjct: 87 SVSFNHLDLNSINNKINNNTTTNNNNNNNNNNDDKFDTNALKLSNTMIIKNNNNNNNNNN 146
Query: 670 RGRQLVGPIEKKNNSRSRSFEPEPDTSRNNGNSTTLNNRYANSNV 804
NN+ + + + + NN N+ NN +NSN+
Sbjct: 147 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNI 191
>sp|Q9UTJ8|RAD50_SCHPO DNA repair protein rad50
Length = 1290
Score = 33.5 bits (75), Expect = 0.83
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 2/151 (1%)
Frame = +1
Query: 61 QQTDLRTENIVLRQHASKHDLVQSVLIKHNELCKRIITTQSSLIKDYGIDLPKELEMLYE 240
Q+T ++ + L + S + + + ++ +E KRI +S + +EL
Sbjct: 197 QETQVKVDQATLTHYRSDKERAEKIELRVHESLKRISCIRSKV---------EEL----- 242
Query: 241 LYSDDDITMTNNIKIGLLDIDKDLYNYERNLPV--EIDSSSDIRDMTSNVSVNEVREEDE 414
D +IT T ++ L K YE+ + ++S SDI + T N +++ DE
Sbjct: 243 ---DQEITETARLQDELF---KSTEEYEQQMITIRHLESQSDIINTTINDLKSQMTITDE 296
Query: 415 SLASLPLIHNPHATPESWDNDSLRQAHKKSS 507
S L +H+ A + + + KK S
Sbjct: 297 SSEDLEKLHSNFAEKVKEEQELYKSLEKKRS 327
>sp|Q20845|PLK3_CAEEL Serine/threonine-protein kinase plk-3 (Polo-like kinase 3)
Length = 615
Score = 33.1 bits (74), Expect = 1.1
Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 9/102 (8%)
Frame = +1
Query: 346 DSSSDIRDMTSNVSVNEVREEDESLASLPLIHNPHATPESW-------DNDSLRQAHKKS 504
D S ++ S++ N V +++S L H+P ATP W N + ++
Sbjct: 353 DELSQLQAQISHILQNVVASKNKSSTRFGLNHSPEATPIFWVSQWVHFPNHGIGYRLCEN 412
Query: 505 SFNSFFQTNFDTKYN-AGPKPAFESVSNTNRNFMMS-KPPIN 624
S F N K N AG + F +NT + + M+ + P+N
Sbjct: 413 SSGMLFNDNTQMKVNSAGNQLTFVDENNTEQFYTMNDQVPMN 454
>sp|Q5UIP0|RIF1_HUMAN Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog)
Length = 2472
Score = 33.1 bits (74), Expect = 1.1
Identities = 56/257 (21%), Positives = 101/257 (39%), Gaps = 16/257 (6%)
Frame = +1
Query: 49 KLEIQQTDLRTENIVLRQHASKHDLVQSVLIKHNELCKRIITT-QSSLIKDYGIDLPKEL 225
KL+++ + L+ + +L + D V + + + +RI+T Q ++K D+P
Sbjct: 1025 KLKLESSSLKVKGEILLEEEKSTDFV-FIPPEGKDAKERILTDHQKEVLKTKRCDIP--- 1080
Query: 226 EMLYELYSDDDITMTNNIKIGLLDIDKDLY--NYERNLPVEIDSSSDIRDMTSNVSVNEV 399
M NN LD+ +D Y + P+EI + + S + + E
Sbjct: 1081 ------------AMYNN-----LDVSQDTLFTQYSQEEPMEIPTLTRKPKEDSKMMITEE 1123
Query: 400 REEDESLASLPLIHN----PHATPESWDNDSLRQAHKKSSFNSFFQTNFDTKYNA---GP 558
+ + + + + + H S N+ K S S +N D + A
Sbjct: 1124 QMDSDIVIPQDVTEDCGMAEHLEKSSLSNNECGSLDKTSPEMS--NSNNDERKKALISSR 1181
Query: 559 KPAFESVSNTNRNFMMSKPPINQL------PYRTTNKSILPDLRGRQLVGPIEKKNNSRS 720
K + E S+T +F++S ++ PY T+ RQ +EK + S +
Sbjct: 1182 KTSTECASSTENSFVVSSSSVSNTTVAGTPPYPTSR---------RQTFITLEKFDGSEN 1232
Query: 721 RSFEPEPDTSRNNGNST 771
R F P P NN +ST
Sbjct: 1233 RPFSPSP---LNNISST 1246
>sp|P09547|SWI1_YEAST Transcription regulatory protein SWI1 (SWI/SNF complex component
SWI1) (Transcription regulatory protein ADR6)
(Regulatory protein GAM3)
Length = 1314
Score = 32.7 bits (73), Expect = 1.4
Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Frame = +1
Query: 529 NFDTKYNAGPKPAFESVSNTNRNFMMSKPPINQ--LPYRTTNKSILPDLRGRQLVGPIEK 702
+F T + + + S NTN N S P NQ LP+ + S +L QL+
Sbjct: 205 HFITNVQSISQNSSSSTPNTNSN---STPNANQQFLPFNNS-ASNNGNLTSNQLISNYAA 260
Query: 703 KNN---SRSRSFEPEPDTSRNNGNSTTLNNRYANSN 801
N+ S S S E P+TS NN NS N R ++N
Sbjct: 261 SNSMDRSSSASNEFVPNTSDNNNNSNNHNMRNNSNN 296
>sp|Q06168|SFH1_YEAST Chromatin structure remodeling complex protein SFH1 (SNF5 homolog
1)
Length = 426
Score = 32.7 bits (73), Expect = 1.4
Identities = 16/46 (34%), Positives = 24/46 (52%)
Frame = +1
Query: 535 DTKYNAGPKPAFESVSNTNRNFMMSKPPINQLPYRTTNKSILPDLR 672
+ KY+AG ES+S N N S P N+ + ++LPDL+
Sbjct: 111 NNKYDAGSNMVVESLSGLNSNNNASNGPSNKAQAQDIGNAVLPDLQ 156
>sp|Q9NFU0|FXR1_DROME Fragile X mental retardation syndrome-related protein 1 (dFMR1)
(dfxr)
Length = 684
Score = 32.0 bits (71), Expect = 2.4
Identities = 28/114 (24%), Positives = 46/114 (40%), Gaps = 5/114 (4%)
Frame = +1
Query: 439 HNPHATPE---SWDNDSLRQAHKKSSFNSFFQTNFDTKYNAGPKPAFESVSNTNRNFMMS 609
H+ H T E + + S+ +A SS+ + K N GP +V+N N +
Sbjct: 517 HHNHTTEEVRETREMSSVERADSNSSYEGSSRRRRRQKNNNGPSNTNGAVANNNNKPQSA 576
Query: 610 KPPINQLPYRTTNKSILPDLRGRQLVGPIEKKN--NSRSRSFEPEPDTSRNNGN 765
+ P Q P NK+ L G K+N N+ + +P + NG+
Sbjct: 577 QQPQQQQPPAPGNKAALN-------AGDASKQNSGNANAAGGASKPKDASRNGD 623
>sp|Q5FIN5|SYS_LACAC Seryl-tRNA synthetase (Serine--tRNA ligase) (SerRS)
Length = 435
Score = 32.0 bits (71), Expect = 2.4
Identities = 27/125 (21%), Positives = 61/125 (48%), Gaps = 11/125 (8%)
Frame = +1
Query: 214 PKELEMLYELYSD--DDITMTNNIKIGLLDIDKDLYNYERNLPVEIDSSSDIRDMTSNV- 384
P+EL+ L E+ + D+TM+ +K D+ K + +RN D+ +++R++ +
Sbjct: 25 PEELDELVEIDTKRRKDLTMSEQLKAKRNDVSKQIAEKKRNKEDASDAIAEMREVGKEIK 84
Query: 385 ----SVNEVREEDE----SLASLPLIHNPHATPESWDNDSLRQAHKKSSFNSFFQTNFDT 540
V+E+ E+ L + P +P +S+ N+ +R+ + + F+ + ++D
Sbjct: 85 KLDKEVDELTEKQNYILLRLPNFPADSDPIGPDDSY-NEEVRKWEEPTKFDFKPKAHWDL 143
Query: 541 KYNAG 555
+ G
Sbjct: 144 GTDLG 148
>sp|Q9ZK27|SYH_HELPJ Histidyl-tRNA synthetase (Histidine--tRNA ligase) (HisRS)
Length = 442
Score = 32.0 bits (71), Expect = 2.4
Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Frame = +1
Query: 4 IRHEGQMLQLLCRMHKLEIQQTDLRTENIVLRQHASKHDLVQSVLIKHNELCKRIITTQS 183
I ++L+++ ++ K+ + + + + DL++ V IK N+L +
Sbjct: 175 IAQVNEVLRIVDKLEKIGLNGVEEELKKECDLDSNTIKDLLEMVQIKQNDLSHAEFFEKI 234
Query: 184 SLIKDYGIDLPK---ELEMLYELYSDDDIT 264
+ +KDY +L K +LE LY+L D I+
Sbjct: 235 AYLKDYNENLKKGIQDLERLYQLLGDLQIS 264
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.314 0.132 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 104,228,881
Number of Sequences: 369166
Number of extensions: 2173924
Number of successful extensions: 5388
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4872
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5232
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9030416440
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)