Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_H23
(867 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26779|SAP_BOVIN Proactivator polypeptide precursor [Con... 63 1e-09
sp|O13035|SAP_CHICK Proactivator polypeptide precursor [Con... 56 1e-07
sp|P07602|SAP_HUMAN Proactivator polypeptide precursor [Con... 52 2e-06
sp|P10960|SAP_RAT Sulfated glycoprotein 1 precursor (SGP-1)... 49 1e-05
sp|Q61207|SAP_MOUSE Sulfated glycoprotein 1 precursor (SGP-... 49 2e-05
sp|P50405|PSPB_MOUSE Pulmonary surfactant-associated protei... 48 4e-05
sp|P22355|PSPB_RAT Pulmonary surfactant-associated protein ... 46 1e-04
sp|P17129|PSPB_CANFA Pulmonary surfactant-associated protei... 45 3e-04
sp|P07988|PSPB_HUMAN Pulmonary surfactant-associated protei... 37 0.092
sp|P34095|PFPA_ENTHI Pore-forming peptide ameobapore A prec... 36 0.12
>sp|P26779|SAP_BOVIN Proactivator polypeptide precursor [Contains: Saposin A (Protein
A); Saposin B (Sphingolipid activator protein 1) (SAP-1)
(Cerebroside sulfate activator) (CSAct) (Dispersin)
(Sulfatide/GM1 activator); Saposin C
(Co-beta-glucosidase) (A1 activator) (Glucosylceramidase
activator) (Sphingolipid activator protein 2) (SAP-2);
Saposin D (Protein C) (Component C)]
Length = 525
Score = 62.8 bits (151), Expect = 1e-09
Identities = 44/194 (22%), Positives = 80/194 (41%), Gaps = 1/194 (0%)
Frame = +3
Query: 150 KLPYVASKSETCNTCIQFVRVVESKIPK-LTEKEFINLINTFICDRIQVNTHWKCRDFVA 326
K P A C C V+ V I TE+E ++ ++ +C ++ + +C++ V
Sbjct: 305 KDPAPAKADIYCEVCEFVVKEVAKLIDNNRTEEEILHALDK-VCSKLPTSLAEQCQEVVD 363
Query: 327 EFGPLIYEEIKTEATPEKICGLIQACENQKEMSXXXXXXXXXXXXELCAKCKEIFDFLDA 506
+G I + EA+PE +C ++ C + + + C CK++ +LD
Sbjct: 364 TYGRSILSILLDEASPELVCSMLHLC-SSRGLPAATVRVMPRKDGGFCEVCKKLVGYLDR 422
Query: 507 MFSKVTPDEFKYLLETLVCSQLPSEFRDTCKALLDGYVTQLYYLIKSLLDGDRICPLIHF 686
K + E CS LP ++R C + Y L ++ ++D +C I
Sbjct: 423 NLEKNSTKEQILAALEKGCSFLPDQYRKQCDQFVTEYEPVLIEILVEVMDPSFVCLKIGA 482
Query: 687 CPSNTTVTLNSWNC 728
CP+ L + C
Sbjct: 483 CPAAHKPLLGAEKC 496
Score = 48.1 bits (113), Expect = 3e-05
Identities = 50/253 (19%), Positives = 97/253 (38%), Gaps = 37/253 (14%)
Frame = +3
Query: 123 DKMNSKKENKLPYVASKSETCNTCIQFVRVVESKIPKLTEKEFINLINTFI---CDRIQV 293
D +SK + K + C CIQ V V+ + T F+ + CDR+
Sbjct: 183 DGSHSKPQPK----KANGNVCQDCIQLVTDVQEALR--TNSTFVEALVDHAKEECDRLGP 236
Query: 294 NTHWKCRDFVAEFGPLIYEEIKTEATPEKICGLIQACENQKEMSXXXXXXXXXXXXEL-- 467
C++++ ++ + + + P++IC L C+ KEM +
Sbjct: 237 GMSDMCKNYINQYSEVAIQMVM-HMQPKEICVLAGFCDEVKEMPMKTLVPAEVVSENVIP 295
Query: 468 --------------------CAKC----KEIFDFLDAMFSKVTPDEFKYLLETLVCSQLP 575
C C KE+ +D + T +E + L+ VCS+LP
Sbjct: 296 ALGLVEPIKKDPAPAKADIYCEVCEFVVKEVAKLID---NNRTEEEILHALDK-VCSKLP 351
Query: 576 SEFRDTCKALLDGYVTQLYYLIKSLLDGDRICPLIHFCPSN----TTVTL----NSWNCQ 731
+ + C+ ++D Y + ++ + +C ++H C S TV + + C+
Sbjct: 352 TSLAEQCQEVVDTYGRSILSILLDEASPELVCSMLHLCSSRGLPAATVRVMPRKDGGFCE 411
Query: 732 TCLDVVVMLKKDM 770
C +V L +++
Sbjct: 412 VCKKLVGYLDRNL 424
Score = 47.4 bits (111), Expect = 5e-05
Identities = 31/132 (23%), Positives = 57/132 (43%), Gaps = 4/132 (3%)
Frame = +3
Query: 42 DCLKGPNFWCATFKNAEKCGKITECFMDKMNSKKENKLPYVASKSETCNTCIQFVRVVES 221
+C +G WC K A CG + C + LP C+ C + +
Sbjct: 24 ECTRGSAVWCQNVKTAADCGAVQHCLQTVWSKPTVKSLP--------CDICKDVITAAGN 75
Query: 222 KI-PKLTEKEFINLINTFICDRI-QVNTHWKCRDFVAEFGPLIYEEIKTEAT-PEKICGL 392
+ TE+E + + CD + + N C++ V + P+I + IK + + P ++C
Sbjct: 76 LLKDNATEQEILMYLER-TCDWLPKPNMSASCKEIVDSYLPVILDMIKGQMSHPGEVCSA 134
Query: 393 IQACEN-QKEMS 425
+ CE+ QK ++
Sbjct: 135 LNLCESLQKHLA 146
>sp|O13035|SAP_CHICK Proactivator polypeptide precursor [Contains: Saposin A; Saposin B;
Saposin C; Saposin D]
Length = 518
Score = 56.2 bits (134), Expect = 1e-07
Identities = 62/296 (20%), Positives = 111/296 (37%), Gaps = 44/296 (14%)
Frame = +3
Query: 42 DCLKGPNFWCATFKNAEKCGKITECFMDKMNSKKENKLPYVASKSETCNTCIQFVRVVES 221
DC KGP WC + + A +CG + C + + N +P C+ C + V VV
Sbjct: 25 DCAKGPEVWCQSLRTASQCGAVKHCQQNVWSKPAVNSIP--------CDLCKELVTVVGK 76
Query: 222 KI-PKLTEKEFINLIN---TFICDRIQVNTHWKCRDFVAEFGPLIYEEIKTE-ATPEKIC 386
+ TE E + + F+ D+ + +C++ V + P+I + IK E PE +C
Sbjct: 77 VLKDNGTEDEIRSYLEKRCEFLPDQGLAS---ECKEIVDSYLPVIMDMIKEEFDKPEVVC 133
Query: 387 GLIQACEN----------QKEMS--------------------------XXXXXXXXXXX 458
+ C++ QK++
Sbjct: 134 SALSLCQSLQKHLAAMKLQKQLQSNKIPELDFSELTSPFMANVPLLLYPQDKPKQKSKAT 193
Query: 459 XELCAKC-KEIFDFLDAMFSKVTPDEFKYLLETLVCSQLPSEFRDTCKALLDGYVTQLYY 635
++C C + + D +A+ + T + C +L D CK+ + Y
Sbjct: 194 EDVCQDCIRLVTDVQEAVRTNATFVKSLVAHAKEECDRLGPGMSDMCKSYISEYSDLAIQ 253
Query: 636 LIKSLLDGD--RICPLIHFCPSNTTVTLNSWNCQTCLDVVVMLKKDMVNVPASEVE 797
++ + D IC ++ FCPS +V L QT + V+ + M V + V+
Sbjct: 254 MMMHMKDQQPKDICAMVGFCPSVKSVPL-----QTLVPAQVVHEVKMETVEKATVQ 304
Score = 55.8 bits (133), Expect = 1e-07
Identities = 39/171 (22%), Positives = 69/171 (40%), Gaps = 2/171 (1%)
Frame = +3
Query: 183 CNTCIQFVRVVESKIPK-LTEKEFINLINTFICDRIQVNTHWKCRDFVAEFGPLIYEEIK 359
C C V+ V + TE+E ++ + +C + + +C+DF+ +G + + +
Sbjct: 311 CEICETMVKEVTGLLESNKTEEEIVHEMEV-VCYLLPASVKDQCKDFIEVYGQALIDMLL 369
Query: 360 TEATPEKICGLIQACENQKEMSXXXXXXXXXXXXELCAKCKEIFDFLDAMFSK-VTPDEF 536
PE +C +++ C K C CK I + D K T E
Sbjct: 370 EATNPEAVCVMLKCCAANKPPQQPVVVKPAGG---FCDICKMIVAYADKELEKNATTTEI 426
Query: 537 KYLLETLVCSQLPSEFRDTCKALLDGYVTQLYYLIKSLLDGDRICPLIHFC 689
+ LLE VC LP D C ++ Y + L+ ++D +C + C
Sbjct: 427 EALLEK-VCHFLPESVSDQCVQFVEQYEPVVVQLLAEMMDPTFVCTKLGVC 476
Score = 53.5 bits (127), Expect = 7e-07
Identities = 50/243 (20%), Positives = 96/243 (39%), Gaps = 32/243 (13%)
Frame = +3
Query: 177 ETCNTCIQFVRVVESKIPKLTEKEFINLINTFI---CDRIQVNTHWKCRDFVAEFGPLIY 347
+ C CI+ V V+ + T F+ + CDR+ C+ +++E+ L
Sbjct: 195 DVCQDCIRLVTDVQEAVR--TNATFVKSLVAHAKEECDRLGPGMSDMCKSYISEYSDLAI 252
Query: 348 EEIK--TEATPEKICGLIQACENQK----------------EMSXXXXXXXXXXXXELCA 473
+ + + P+ IC ++ C + K +M +C
Sbjct: 253 QMMMHMKDQQPKDICAMVGFCPSVKSVPLQTLVPAQVVHEVKMETVEKATVQEKTFSVCE 312
Query: 474 KC----KEIFDFLDAMFSKVTPDEFKYLLETLVCSQLPSEFRDTCKALLDGYVTQLYYLI 641
C KE+ L+ S T +E + +E +VC LP+ +D CK ++ Y L ++
Sbjct: 313 ICETMVKEVTGLLE---SNKTEEEIVHEME-VVCYLLPASVKDQCKDFIEVYGQALIDML 368
Query: 642 KSLLDGDRICPLIHFCPSN------TTVTLNSWNCQTCLDVVVMLKKDM-VNVPASEVEA 800
+ + +C ++ C +N V C C +V K++ N +E+EA
Sbjct: 369 LEATNPEAVCVMLKCCAANKPPQQPVVVKPAGGFCDICKMIVAYADKELEKNATTTEIEA 428
Query: 801 LIK 809
L++
Sbjct: 429 LLE 431
Score = 30.0 bits (66), Expect = 8.7
Identities = 8/24 (33%), Positives = 13/24 (54%)
Frame = +3
Query: 45 CLKGPNFWCATFKNAEKCGKITEC 116
C+ GP +WC + A +C + C
Sbjct: 489 CVWGPGYWCKNMETAAQCNAVDHC 512
>sp|P07602|SAP_HUMAN Proactivator polypeptide precursor [Contains: Saposin A (Protein
A); Saposin B-Val; Saposin B (Sphingolipid activator
protein 1) (SAP-1) (Cerebroside sulfate activator)
(CSAct) (Dispersin) (Sulfatide/GM1 activator); Saposin C
(Co-beta-glucosidase) (A1 activator) (Glucosylceramidase
activator) (Sphingolipid activator protein 2) (SAP-2);
Saposin D (Protein C) (Component C)]
Length = 524
Score = 52.0 bits (123), Expect = 2e-06
Identities = 44/238 (18%), Positives = 94/238 (39%), Gaps = 33/238 (13%)
Frame = +3
Query: 156 PYVASKSETCNTCIQFVRVVESKIPKLTEKEFINLINTFI---CDRIQVNTHWKCRDFVA 326
P + C CIQ V +++ + T F+ + + CDR+ C+++++
Sbjct: 189 PQPKDNGDVCQDCIQMVTDIQTAVR--TNSTFVQALVEHVKEECDRLGPGMADICKNYIS 246
Query: 327 EFGPLIYEEIKTEATPEKICGLIQACENQKEMSXXXXXXXXXXXX--------------- 461
++ + + + P++IC L+ C+ KEM
Sbjct: 247 QYSEIAIQ-MMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKH 305
Query: 462 ELCAKCKEIFDFLDAMFSKVTP--DEFKYLLETL-----VCSQLPSEFRDTCKALLDGYV 620
E+ AK + + + +VT D K E L +CS+LP + C+ ++D Y
Sbjct: 306 EVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYG 365
Query: 621 TQLYYLIKSLLDGDRICPLIHFCPS--------NTTVTLNSWNCQTCLDVVVMLKKDM 770
+ + ++ + + +C ++H C + T + C+ C +V L +++
Sbjct: 366 SSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNL 423
Score = 51.2 bits (121), Expect = 4e-06
Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 3/131 (2%)
Frame = +3
Query: 42 DCLKGPNFWCATFKNAEKCGKITECFMDKMNSKKENKLPYVASKSETCNTCIQFVRVVES 221
+C +G WC K A CG + C N LP C+ C V
Sbjct: 24 ECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLP--------CDICKDVVTAAGD 75
Query: 222 KIPKLTEKEFINLINTFICDRI-QVNTHWKCRDFVAEFGPLIYEEIKTE-ATPEKICGLI 395
+ +E I + CD + + N C++ V + P+I + IK E + P ++C +
Sbjct: 76 MLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSAL 135
Query: 396 QACEN-QKEMS 425
CE+ QK ++
Sbjct: 136 NLCESLQKHLA 146
Score = 31.6 bits (70), Expect = 3.0
Identities = 19/74 (25%), Positives = 32/74 (43%)
Frame = +3
Query: 183 CNTCIQFVRVVESKIPKLTEKEFINLINTFICDRIQVNTHWKCRDFVAEFGPLIYEEIKT 362
C C + V ++ + K + K+ I C + +C FVAE+ P++ E +
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 363 EATPEKICGLIQAC 404
P +C I AC
Sbjct: 469 VMDPSFVCLKIGAC 482
Score = 30.0 bits (66), Expect = 8.7
Identities = 8/24 (33%), Positives = 14/24 (58%)
Frame = +3
Query: 45 CLKGPNFWCATFKNAEKCGKITEC 116
C+ GP++WC + A +C + C
Sbjct: 495 CIWGPSYWCQNTETAAQCNAVEHC 518
>sp|P10960|SAP_RAT Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin)
Length = 554
Score = 49.3 bits (116), Expect = 1e-05
Identities = 42/213 (19%), Positives = 73/213 (34%), Gaps = 31/213 (14%)
Frame = +3
Query: 183 CNTCIQFVRVVESKIPKLTEKEFINLINTFICDRIQVNTHWKCRDFVAEFGPLIYEEIKT 362
C C +R + I +E + + C + KC++ + FGP + + +
Sbjct: 314 CQVCQLVMRKLSELIINNATEELLIKGLSKACSLLPAPASTKCQEVLVTFGPSLLDVLMH 373
Query: 363 EATPEKICGLIQACE------------------------------NQKEMSXXXXXXXXX 452
E P +CG+I C + + S
Sbjct: 374 EVNPNFLCGVISLCSANPNLVGTLEQPAAAIVSALPKEPAPPKQPEEPKQSALRAHVPPQ 433
Query: 453 XXXELCAKCKEIFDFLDAMFSK-VTPDEFKYLLETLVCSQLPSEFRDTCKALLDGYVTQL 629
C CK++ +L+ K T +E LE CS LP ++ C + Y L
Sbjct: 434 KNGGFCEVCKKLVIYLEHNLEKNSTKEEILAALEK-GCSFLPDPYQKQCDEFVAEYEPLL 492
Query: 630 YYLIKSLLDGDRICPLIHFCPSNTTVTLNSWNC 728
++ ++D +C I CPS + L + C
Sbjct: 493 LEILVEVMDPSFVCSKIGVCPSAYKLLLGTEKC 525
>sp|Q61207|SAP_MOUSE Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin)
Length = 557
Score = 48.5 bits (114), Expect = 2e-05
Identities = 48/215 (22%), Positives = 78/215 (36%), Gaps = 33/215 (15%)
Frame = +3
Query: 183 CNTCIQFV--RVVESKIPKLTEKEFINLINTFICDRIQVNTHWKCRDFVAEFGPLIYEEI 356
C TC QFV + E + TE+ + ++ C + KC++ V FGP + +
Sbjct: 317 CQTC-QFVMNKFSELIVNNATEELLVKGLSN-ACALLPDPARTKCQEVVGTFGPSLLDIF 374
Query: 357 KTEATPEKICGLIQACENQKEM------------------------------SXXXXXXX 446
E P +CG+I C + E+ S
Sbjct: 375 IHEVNPSSLCGVIGLCAARPELVEALEQPAPAIVSALLKEPTPPKQPAQPKQSALPAHVP 434
Query: 447 XXXXXELCAKCKEIFDFLDAMFSK-VTPDEFKYLLETLVCSQLPSEFRDTCKALLDGYVT 623
C CK++ +L+ K T +E LE CS LP ++ C + Y
Sbjct: 435 PQKNGGFCEVCKKLVLYLEHNLEKNSTKEEILAALEK-GCSFLPDPYQKQCDDFVAEYEP 493
Query: 624 QLYYLIKSLLDGDRICPLIHFCPSNTTVTLNSWNC 728
L ++ ++D +C I CPS + L + C
Sbjct: 494 LLLEILVEVMDPGFVCSKIGVCPSAYKLLLGTEKC 528
Score = 30.8 bits (68), Expect = 5.1
Identities = 8/24 (33%), Positives = 14/24 (58%)
Frame = +3
Query: 45 CLKGPNFWCATFKNAEKCGKITEC 116
C+ GP++WC + A +C + C
Sbjct: 528 CVWGPSYWCQNMETAARCNAVDHC 551
>sp|P50405|PSPB_MOUSE Pulmonary surfactant-associated protein B precursor (SP-B)
(Pulmonary surfactant-associated proteolipid SPL(Phe))
Length = 377
Score = 47.8 bits (112), Expect = 4e-05
Identities = 30/133 (22%), Positives = 59/133 (44%), Gaps = 4/133 (3%)
Frame = +3
Query: 18 SVCYAFDFDCLKGPNFWCATFKNAEKCGKITECFMDKMNSKKENKLPYVASKSETCNTCI 197
++ A +C +GP FWC + ++A +C + C + A ++ C C
Sbjct: 22 AITSASSLECAQGPQFWCQSLEHAVQCRALGHCLQEVWGH---------AGANDLCQECE 72
Query: 198 QFVRVVESKIPKLTEKEFINLINTFI---CDRIQVNTHW-KCRDFVAEFGPLIYEEIKTE 365
V ++ +K+ K E F I F+ CD + + +CR + + PL+ + +++
Sbjct: 73 DIVHLL-TKMTK--EDAFQEAIRKFLEQECDILPLKLLVPRCRQVLDVYLPLVIDYFQSQ 129
Query: 366 ATPEKICGLIQAC 404
P+ IC + C
Sbjct: 130 INPKAICNHVGLC 142
>sp|P22355|PSPB_RAT Pulmonary surfactant-associated protein B precursor (SP-B)
(Pulmonary surfactant-associated proteolipid SPL(Phe))
Length = 376
Score = 46.2 bits (108), Expect = 1e-04
Identities = 30/125 (24%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +3
Query: 42 DCLKGPNFWCATFKNAEKCGKITECFMDKMNSKKENKLPYVASKSETCNTCIQFVRVVES 221
DC +GP FWC + + A +C + C + A ++ C C V ++ +
Sbjct: 29 DCAQGPKFWCQSLEQAIQCRALGHCLQEVWGH---------AGANDLCQECEDIVHLL-T 78
Query: 222 KIPKLTEKEFINLINTFI---CDRIQVNTHW-KCRDFVAEFGPLIYEEIKTEATPEKICG 389
K+ K E F + I F+ CD + + +CR + + PL+ + + + P+ IC
Sbjct: 79 KMTK--EDAFQDTIRKFLEQECDILPLKLLVPRCRQVLDVYLPLVIDYFQGQIKPKAICS 136
Query: 390 LIQAC 404
+ C
Sbjct: 137 HVGLC 141
>sp|P17129|PSPB_CANFA Pulmonary surfactant-associated protein B precursor (SP-B) (6 kDa
protein) (Pulmonary surfactant-associated proteolipid
SPL(Phe)) (Pulmonary surfactant protein 18) (SP 18)
Length = 363
Score = 45.1 bits (105), Expect = 3e-04
Identities = 27/125 (21%), Positives = 58/125 (46%), Gaps = 4/125 (3%)
Frame = +3
Query: 45 CLKGPNFWCATFKNAEKCGKITECFMDKMNSKKENKLPYVASKSETCNTCIQFVRVVESK 224
C +GP FWC + + A +C + C + + + + L C C VR++ +K
Sbjct: 25 CARGPAFWCQSLEQALQCRALGHCLQEVWGNARADDL---------CQECQDIVRIL-TK 74
Query: 225 IPKLTEKEFINLINTFI---CDRIQVNTHW-KCRDFVAEFGPLIYEEIKTEATPEKICGL 392
+ K E F +++ F+ CD + + +C + + P++ + +++ P+ IC
Sbjct: 75 MTK--EAIFQDMVRKFLEHECDVLPLKLLTPQCHHMLGTYFPVVVDYFQSQINPKIICKH 132
Query: 393 IQACE 407
+ C+
Sbjct: 133 LGLCK 137
>sp|P07988|PSPB_HUMAN Pulmonary surfactant-associated protein B precursor (SP-B) (6 kDa
protein) (Pulmonary surfactant-associated proteolipid
SPL(Phe)) (18 kDa pulmonary-surfactant protein)
Length = 381
Score = 36.6 bits (83), Expect = 0.092
Identities = 24/128 (18%), Positives = 54/128 (42%), Gaps = 4/128 (3%)
Frame = +3
Query: 45 CLKGPNFWCATFKNAEKCGKITECFMDKMNSKKENKLPYVASKSETCNTCIQFVRVVESK 224
C +GP FWC + + A +C + C + + C C V ++ +K
Sbjct: 32 CAQGPEFWCQSLEQALQCRALGHCLQEVWGH---------VGADDLCQECEDIVHIL-NK 81
Query: 225 IPKLTEKEFINLINTFI---CDRIQVNTHW-KCRDFVAEFGPLIYEEIKTEATPEKICGL 392
+ K E F + + F+ C+ + + +C + ++ PL+ + + + IC
Sbjct: 82 MAK--EAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMH 139
Query: 393 IQACENQK 416
+ C++++
Sbjct: 140 LGLCKSRQ 147
Score = 30.8 bits (68), Expect = 5.1
Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +3
Query: 462 ELCAKCKEIFDFLDAMFSK-VTPDEFKYLLETLVCSQLPSEF-RDTCKALLDGYVTQLYY 635
+LC +C++I L+ M + + D + LE C+ LP + C +LD Y +
Sbjct: 67 DLCQECEDIVHILNKMAKEAIFQDTMRKFLEQ-ECNVLPLKLLMPQCNQVLDDYFPLVID 125
Query: 636 LIKSLLDGDRICPLIHFCPS 695
++ D + IC + C S
Sbjct: 126 YFQNQTDSNGICMHLGLCKS 145
>sp|P34095|PFPA_ENTHI Pore-forming peptide ameobapore A precursor (EH-APP)
Length = 98
Score = 36.2 bits (82), Expect = 0.12
Identities = 20/75 (26%), Positives = 36/75 (48%)
Frame = +3
Query: 465 LCAKCKEIFDFLDAMFSKVTPDEFKYLLETLVCSQLPSEFRDTCKALLDGYVTQLYYLIK 644
LC C + + L+ + + D+ K + +L C++ C +LD + +L LI+
Sbjct: 25 LCNLCTGLINTLENLLTTKGADKVKDYISSL-CNKASGFIATLCTKVLDFGIDKLIQLIE 83
Query: 645 SLLDGDRICPLIHFC 689
+D + IC IH C
Sbjct: 84 DKVDANAICAKIHAC 98
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,155,909
Number of Sequences: 369166
Number of extensions: 1782885
Number of successful extensions: 4332
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4193
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4325
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8550075140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)