Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_H15
(339 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q19673|TYR3_CAEEL Putative tyrosinase-like protein tyr-3... 66 3e-11
sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precurs... 53 3e-07
sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1... 50 1e-06
sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precurs... 49 3e-06
sp|P30652|YOW6_CAEEL Hypothetical protein ZK643.6 precursor 42 3e-04
sp|P54190|TES26_TOXCA 26 kDa secreted antigen precursor (To... 42 6e-04
sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1) 39 0.004
sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1) 39 0.004
sp|P78504|JAG1_HUMAN Jagged-1 precursor (Jagged1) (hJ1) (CD... 39 0.005
sp|P91137|NAS9_CAEEL Zinc metalloproteinase nas-9 precursor... 39 0.005
>sp|Q19673|TYR3_CAEEL Putative tyrosinase-like protein tyr-3 precursor
Length = 683
Score = 65.9 bits (159), Expect = 3e-11
Identities = 37/124 (29%), Positives = 46/124 (37%), Gaps = 38/124 (30%)
Frame = +1
Query: 1 CRDARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC----------GG 150
CR N C D +C W+ +GEC NP W +NC SCQ C GG
Sbjct: 493 CRQCTPNYNINEECSDRHTNCAMWSRSGECNKNPLWMSENCRSSCQKCGRSRAATCGGGG 552
Query: 151 CRDLIQN----------------------------CQNFANQGYCKTNEVYMNQSCKKTC 246
D I N C +A +G C++N YM CK +C
Sbjct: 553 GADSISNPTTMPPATNNGQQNTPCDSPMCYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSC 612
Query: 247 GFCR 258
G CR
Sbjct: 613 GVCR 616
Score = 55.5 bits (132), Expect = 4e-08
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
Frame = +1
Query: 31 NPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC------GGCRDLIQNCQNFANQ 192
+P C + C WA G+C+ NPG+ C SC C G C D +C +A +
Sbjct: 578 SPMCYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRPNYVYGPCADYHYDCAAWARR 637
Query: 193 GYCKTNEVYMNQSCKKTCGFC 255
G C N+ +M ++C+++C C
Sbjct: 638 GECLKNK-WMPENCRRSCNTC 657
Score = 51.6 bits (122), Expect = 6e-07
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 7/72 (9%)
Frame = +1
Query: 61 CLYWANAGECQLNPGWAKQNCPFSCQHCGG-------CRDLIQNCQNFANQGYCKTNEVY 219
C W+ GECQ NP + C SC+ C C D NC ++ G C N ++
Sbjct: 469 CGPWSAKGECQKNPVYMNVWCKASCRQCTPNYNINEECSDRHTNCAMWSRSGECNKNPLW 528
Query: 220 MNQSCKKTCGFC 255
M+++C+ +C C
Sbjct: 529 MSENCRSSCQKC 540
Score = 38.1 bits (87), Expect = 0.006
Identities = 17/45 (37%), Positives = 19/45 (42%)
Frame = +1
Query: 40 CKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCGGCRDLIQNC 174
C D C WA GEC N W +NC SC C + L C
Sbjct: 624 CADYHYDCAAWARRGECLKNK-WMPENCRRSCNTCVNQQQLAARC 667
>sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precursor (Nematode astacin 15)
Length = 571
Score = 52.8 bits (125), Expect = 3e-07
Identities = 31/118 (26%), Positives = 41/118 (34%), Gaps = 46/118 (38%)
Frame = +1
Query: 40 CKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC------------------------- 144
C++L+ C A G C NPGW + NCP SC C
Sbjct: 354 CRNLRGDCDDLAKQGWCIRNPGWMRANCPISCGMCIPTKETQKPYVQTTTQAATTTARPQ 413
Query: 145 ---------------------GGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFC 255
C DL +C +Q YCK ++ +M C K+CGFC
Sbjct: 414 KPVTQPIQPLPPVPPLPPTTPEDCEDLRVDCLVLVSQRYCKISQNFMKSYCAKSCGFC 471
Score = 34.3 bits (77), Expect = 0.092
Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
Frame = +1
Query: 40 CKDLQIHCLYWANAGECQ-LNPGWAKQNCPFSCQHC 144
C D + C +W +AG C+ + + K+NCP SC C
Sbjct: 536 CSDRKHFCSHWKSAGFCEGIFMNYMKKNCPASCGLC 571
Score = 31.2 bits (69), Expect = 0.78
Identities = 11/36 (30%), Positives = 20/36 (55%)
Frame = +1
Query: 37 NCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC 144
+C+DL++ CL + C+++ + K C SC C
Sbjct: 436 DCEDLRVDCLVLVSQRYCKISQNFMKSYCAKSCGFC 471
Score = 28.5 bits (62), Expect = 5.1
Identities = 11/36 (30%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Frame = +1
Query: 151 CRDLIQNCQNFANQGYCKTNEV-YMNQSCKKTCGFC 255
C D C ++ + G+C+ + YM ++C +CG C
Sbjct: 536 CSDRKHFCSHWKSAGFCEGIFMNYMKKNCPASCGLC 571
>sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1 precursor
Length = 601
Score = 50.4 bits (119), Expect = 1e-06
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Frame = +1
Query: 37 NCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCG------GCRDLIQNCQNFANQGY 198
NC + C W+ EC+ N + + C SC C GC D +C + Q +
Sbjct: 479 NCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNF 538
Query: 199 CKTNEVYMNQSCKKTCGFC 255
C +M ++C+ TCG+C
Sbjct: 539 CTRRRQWMAENCQATCGWC 557
Score = 42.4 bits (98), Expect = 3e-04
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +1
Query: 172 CQNFANQGYCKTNEVYMNQSCKKTCGFCR 258
C ++ Q C+TN VYMN+ C+K+CG C+
Sbjct: 487 CNQWSRQNECRTNTVYMNRYCRKSCGLCQ 515
Score = 36.6 bits (83), Expect = 0.019
Identities = 17/55 (30%), Positives = 22/55 (40%)
Frame = +1
Query: 28 SNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCGGCRDLIQNCQNFANQ 192
+N C D I C YW C W +NC +C C + Q C + A Q
Sbjct: 519 NNRGCHDRHISCAYWRGQNFCTRRRQWMAENCQATCGWCN--MNEAQLCASVARQ 571
>sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precursor (Nematode astacin 13)
Length = 527
Score = 49.3 bits (116), Expect = 3e-06
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 11/83 (13%)
Frame = +1
Query: 40 CKDLQIHCLYWANAGECQ--LNPGWAKQNCPFSCQHCGG-------CRDLIQNCQNFANQ 192
C+D + C + A AG C+ + + +NC SC C C D C+ +AN
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWANS 504
Query: 193 GYCKTN--EVYMNQSCKKTCGFC 255
G C + YM Q C K+C FC
Sbjct: 505 GMCNQTVFKDYMRQKCAKSCNFC 527
Score = 31.2 bits (69), Expect = 0.78
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Frame = +1
Query: 145 GGCRDLIQNCQNFANQGYCKT--NEVYMNQSCKKTCGFC 255
G C D ++C+ A G+C++ + +M ++C +CG C
Sbjct: 443 GKCEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKC 481
>sp|P30652|YOW6_CAEEL Hypothetical protein ZK643.6 precursor
Length = 180
Score = 42.4 bits (98), Expect = 3e-04
Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Frame = +1
Query: 40 CKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCGGCRDLIQNCQNFANQGYC-KTNEV 216
C DL C Y N + + CP +C C C D + C + +G+C K +
Sbjct: 107 CTDLANDCSYNQNRCSVKEYSSLMHRLCPKTCNACNICEDANKMCPIWVPRGFCSKFDHD 166
Query: 217 YMNQSCKKTCGFCR 258
+ +SC K+C C+
Sbjct: 167 KVQKSCAKSCNICK 180
Score = 30.0 bits (66), Expect = 1.7
Identities = 18/66 (27%), Positives = 24/66 (36%), Gaps = 19/66 (28%)
Frame = +1
Query: 115 QNCPFSCQHC--------------GG-----CRDLIQNCQNFANQGYCKTNEVYMNQSCK 237
+ CP +C C GG C DL +C N+ K M++ C
Sbjct: 76 EQCPSTCNRCPHNGTNPENKTGGNGGTGTQECTDLANDCSYNQNRCSVKEYSSLMHRLCP 135
Query: 238 KTCGFC 255
KTC C
Sbjct: 136 KTCNAC 141
>sp|P54190|TES26_TOXCA 26 kDa secreted antigen precursor (Toxocara excretory-secretory
antigen 26) (TES-26)
Length = 262
Score = 41.6 bits (96), Expect = 6e-04
Identities = 28/74 (37%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Frame = +1
Query: 40 CKDLQIHCLYWANAGECQLNP-GWAKQN-CPFSCQHCGGCRDLIQNCQNFANQGYCKTNE 213
C D C ANAG C P QN C +C C CRD NC N T E
Sbjct: 23 CMDSASDCA--ANAGSCFTRPVSQVLQNRCQRTCNTCD-CRDEANNCAASINLCQNPTFE 79
Query: 214 VYMNQSCKKTCGFC 255
+ C+KTCG C
Sbjct: 80 PLVRDRCQKTCGLC 93
>sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1)
Length = 1218
Score = 38.9 bits (89), Expect = 0.004
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 32/105 (30%)
Frame = +1
Query: 19 ESISNPNCKDLQIHCLY-----------WANAGECQLNPGWAKQNC--------PFSCQH 141
E S PNC+ + CL ++ EC+ +PGW C P +C H
Sbjct: 326 EGYSGPNCEIAEHACLSDPCHNRGSCKETSSGFECECSPGWTGPTCSTNIDDCSPNNCSH 385
Query: 142 CGGCRDLI-------------QNCQNFANQGYCKTNEVYMNQSCK 237
G C+DL+ + CQ AN+ C+ +SCK
Sbjct: 386 GGTCQDLVNGFKCVCPPQWTGKTCQLDANE--CEAKPCVNARSCK 428
Score = 32.7 bits (73), Expect = 0.27
Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 7/44 (15%)
Frame = +1
Query: 88 CQLNPGWAKQNCPFS-------CQHCGGCRDLIQNCQNFANQGY 198
C PGW QNC + CQ+ CRDL+ + GY
Sbjct: 436 CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGY 479
Score = 32.7 bits (73), Expect = 0.27
Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 2/69 (2%)
Frame = +1
Query: 58 HCLYWANAGECQLNPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMNQS 231
HC N +C G++ C +C C++ Q C N A+ +CK E Y ++
Sbjct: 501 HCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEGKN 559
Query: 232 CKKTCGFCR 258
C CR
Sbjct: 560 CSHLKDHCR 568
>sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1)
Length = 1219
Score = 38.9 bits (89), Expect = 0.004
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 32/105 (30%)
Frame = +1
Query: 19 ESISNPNCKDLQIHCLY-----------WANAGECQLNPGWAKQNC--------PFSCQH 141
E S PNC+ + CL ++ EC+ +PGW C P +C H
Sbjct: 326 EGYSGPNCEIAEHACLSDPCHNRGSCKETSSGFECECSPGWTGPTCSTNIDDCSPNNCSH 385
Query: 142 CGGCRDLI-------------QNCQNFANQGYCKTNEVYMNQSCK 237
G C+DL+ + CQ AN+ C+ +SCK
Sbjct: 386 GGTCQDLVNGFKCVCPPQWTGKTCQLDANE--CEAKPCVNARSCK 428
Score = 32.7 bits (73), Expect = 0.27
Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 7/44 (15%)
Frame = +1
Query: 88 CQLNPGWAKQNCPFS-------CQHCGGCRDLIQNCQNFANQGY 198
C PGW QNC + CQ+ CRDL+ + GY
Sbjct: 436 CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGY 479
Score = 32.7 bits (73), Expect = 0.27
Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 2/69 (2%)
Frame = +1
Query: 58 HCLYWANAGECQLNPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMNQS 231
HC N +C G++ C +C C++ Q C N A+ +CK E Y ++
Sbjct: 501 HCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEGKN 559
Query: 232 CKKTCGFCR 258
C CR
Sbjct: 560 CSHLKDHCR 568
>sp|P78504|JAG1_HUMAN Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen)
Length = 1218
Score = 38.5 bits (88), Expect = 0.005
Identities = 30/105 (28%), Positives = 41/105 (39%), Gaps = 32/105 (30%)
Frame = +1
Query: 19 ESISNPNCKDLQIHCLY--WANAG---------ECQLNPGWAKQNC--------PFSCQH 141
E S PNC+ + CL N G EC+ +PGW C P +C H
Sbjct: 326 EGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSH 385
Query: 142 CGGCRDLI-------------QNCQNFANQGYCKTNEVYMNQSCK 237
G C+DL+ + CQ AN+ C+ +SCK
Sbjct: 386 GGTCQDLVNGFKCVCPPQWTGKTCQLDANE--CEAKPCVNAKSCK 428
Score = 32.7 bits (73), Expect = 0.27
Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 7/44 (15%)
Frame = +1
Query: 88 CQLNPGWAKQNCPFS-------CQHCGGCRDLIQNCQNFANQGY 198
C PGW QNC + CQ+ CRDL+ + GY
Sbjct: 436 CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGY 479
Score = 32.7 bits (73), Expect = 0.27
Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 2/69 (2%)
Frame = +1
Query: 58 HCLYWANAGECQLNPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMNQS 231
HC N +C G++ C +C C++ Q C N A+ +CK E Y ++
Sbjct: 501 HCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEGKN 559
Query: 232 CKKTCGFCR 258
C CR
Sbjct: 560 CSHLKDHCR 568
>sp|P91137|NAS9_CAEEL Zinc metalloproteinase nas-9 precursor (Nematode astacin 9)
Length = 546
Score = 38.5 bits (88), Expect = 0.005
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 2/39 (5%)
Frame = +1
Query: 34 PNCKDLQIHCLYWANAGECQLNP--GWAKQNCPFSCQHC 144
P C D +HC WA G C++ W +NC SC C
Sbjct: 508 PGCDDQNVHCGTWALHGYCKMKEQMKWMNENCKASCDKC 546
Score = 36.2 bits (82), Expect = 0.024
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 2/38 (5%)
Frame = +1
Query: 148 GCRDLIQNCQNFANQGYCKTNE--VYMNQSCKKTCGFC 255
GC D +C +A GYCK E +MN++CK +C C
Sbjct: 509 GCDDQNVHCGTWALHGYCKMKEQMKWMNENCKASCDKC 546
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,339,276
Number of Sequences: 369166
Number of extensions: 689914
Number of successful extensions: 1989
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1650
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1953
length of database: 68,354,980
effective HSP length: 80
effective length of database: 53,576,180
effective search space used: 1714437760
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)