Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_G14
(360 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P69525|TMPS9_MOUSE Transmembrane protease, serine 9 (Pol... 78 7e-15
sp|P69526|TMPS9_RAT Transmembrane protease, serine 9 (Polys... 78 7e-15
sp|P26262|KLKB1_MOUSE Plasma kallikrein precursor (Plasma p... 76 2e-14
sp|Q91VE3|KLK7_MOUSE Kallikrein-7 precursor (Stratum corneu... 76 2e-14
sp|Q7Z410|TMPS9_HUMAN Transmembrane protease, serine 9 (Pol... 76 3e-14
sp|P80420|TRYP_STREX Trypsin-like protease precursor 75 6e-14
sp|Q9UKR3|KLK13_HUMAN Kallikrein 13 precursor (Kallikrein-l... 74 8e-14
sp|Q9I8X2|VSP1_AGKAC Acutobin precursor (Acuthrombin) (Acut... 74 8e-14
sp|Q5U405|TMPSD_MOUSE Transmembrane protease, serine 13 (Mo... 74 1e-13
sp|Q5QSK2|DESC4_RAT Serine protease DESC4 precursor [Contai... 73 2e-13
>sp|P69525|TMPS9_MOUSE Transmembrane protease, serine 9 (Polyserase-1) (Polyserine
protease-1) (Polyserase-I) [Contains: Serase-1; Serase-2;
Serase-3]
Length = 1065
Score = 77.8 bits (190), Expect = 7e-15
Identities = 41/102 (40%), Positives = 56/102 (54%)
Frame = +3
Query: 3 LPPGQDTSRFLQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFC 182
L G +R LQKAA+ ++S C R + V +CAG + SC GD+GGPL C
Sbjct: 963 LREGGSMARQLQKAAVRVLSEQTCRRFYP-VQISSRMLCAGFPQGGVDSCSGDAGGPLAC 1021
Query: 183 TDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWIRAN 308
+ + G+ S+G CG+P+ P VYTRV+ V GWI N
Sbjct: 1022 REPSGQWVLTGVTSWG-YGCGRPHFPGVYTRVAAVLGWIGQN 1062
Score = 66.2 bits (160), Expect = 2e-11
Identities = 35/89 (39%), Positives = 48/89 (53%)
Frame = +3
Query: 33 LQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQV 212
LQKA++ II CG ++ N + +CAG SC+GDSGGPL C +
Sbjct: 647 LQKASVGIIEQKMCGALY-NFSLTDRMLCAGFLEGRVDSCQGDSGGPLACEETPGVFYLA 705
Query: 213 GIVSYGTVPCGQPNVPSVYTRVSEVAGWI 299
GIVS+G + C Q P VY R++ + WI
Sbjct: 706 GIVSWG-IGCAQAKKPGVYARITRLKDWI 733
Score = 65.1 bits (157), Expect = 5e-11
Identities = 34/89 (38%), Positives = 48/89 (53%)
Frame = +3
Query: 33 LQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQV 212
LQKA + ++ S C ++ + R +CAG SC+GDSGGPL C +
Sbjct: 347 LQKATVELLDQSLCSSLYGHSLTDRM-VCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLA 405
Query: 213 GIVSYGTVPCGQPNVPSVYTRVSEVAGWI 299
GIVS+G + C + P VYTRV+ + WI
Sbjct: 406 GIVSWG-IGCAEARRPGVYTRVTRLRDWI 433
>sp|P69526|TMPS9_RAT Transmembrane protease, serine 9 (Polyserase-1) (Polyserine
protease-1) (Polyserase-I) [Contains: Serase-1; Serase-2;
Serase-3]
Length = 1061
Score = 77.8 bits (190), Expect = 7e-15
Identities = 41/102 (40%), Positives = 56/102 (54%)
Frame = +3
Query: 3 LPPGQDTSRFLQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFC 182
L G +R LQKAA+ ++S C R + V +CAG + SC GD+GGPL C
Sbjct: 959 LREGGSMARQLQKAAVRVLSEQTCRRFYP-VQISSRMLCAGFPQGGVDSCSGDAGGPLAC 1017
Query: 183 TDGRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWIRAN 308
+ + G+ S+G CG+P+ P VYTRV+ V GWI N
Sbjct: 1018 REPSGQWVLTGVTSWG-YGCGRPHFPGVYTRVAAVLGWIGQN 1058
Score = 66.2 bits (160), Expect = 2e-11
Identities = 35/89 (39%), Positives = 48/89 (53%)
Frame = +3
Query: 33 LQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQV 212
LQKA++ II CG ++ N + +CAG SC+GDSGGPL C +
Sbjct: 647 LQKASVGIIEQKMCGALY-NFSLTDRMLCAGFLEGRVDSCQGDSGGPLACEETPGVFYLA 705
Query: 213 GIVSYGTVPCGQPNVPSVYTRVSEVAGWI 299
GIVS+G + C Q P VY R++ + WI
Sbjct: 706 GIVSWG-IGCAQAKKPGVYARITRLKDWI 733
Score = 63.5 bits (153), Expect = 1e-10
Identities = 32/89 (35%), Positives = 48/89 (53%)
Frame = +3
Query: 33 LQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQV 212
LQKA + ++ + C ++ + R +CAG SC+GDSGGPL C +
Sbjct: 347 LQKATVELLDQNLCSSLYGHSLTDRM-VCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLA 405
Query: 213 GIVSYGTVPCGQPNVPSVYTRVSEVAGWI 299
G+VS+G + C + P VYTRV+ + WI
Sbjct: 406 GVVSWG-IGCAEARRPGVYTRVTRLRDWI 433
>sp|P26262|KLKB1_MOUSE Plasma kallikrein precursor (Plasma prekallikrein) (Kininogenin)
(Fletcher factor) [Contains: Plasma kallikrein heavy
chain; Plasma kallikrein light chain]
Length = 638
Score = 76.3 bits (186), Expect = 2e-14
Identities = 39/94 (41%), Positives = 54/94 (57%)
Frame = +3
Query: 18 DTSRFLQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDGRK 197
+T LQKA I ++ N EC + + + + ICAG T +C+GDSGGPL C +
Sbjct: 530 ETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEGGTDACKGDSGGPLVCKHSGR 589
Query: 198 HHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWI 299
+ VGI S+G CG+ + P VYT+VSE WI
Sbjct: 590 WQL-VGITSWGE-GCGRKDQPGVYTKVSEYMDWI 621
>sp|Q91VE3|KLK7_MOUSE Kallikrein-7 precursor (Stratum corneum chymotryptic enzyme)
(Thymopsin)
Length = 249
Score = 76.3 bits (186), Expect = 2e-14
Identities = 35/84 (41%), Positives = 54/84 (64%)
Frame = +3
Query: 48 INIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSY 227
+ +IS+ EC +++ ++ ++ +CAG T++C GDSGGPL C D + G+VS+
Sbjct: 164 VKLISSRECKKVYKDLLG-KTMLCAGIPDSKTNTCNGDSGGPLVCNDTLQ-----GLVSW 217
Query: 228 GTVPCGQPNVPSVYTRVSEVAGWI 299
GT PCGQPN P VYT+V + W+
Sbjct: 218 GTYPCGQPNDPGVYTQVCKYKRWV 241
>sp|Q7Z410|TMPS9_HUMAN Transmembrane protease, serine 9 (Polyserase-1) (Polyserase-I)
(Polyserine protease-1) [Contains: Serase-1; Serase-2;
Serase-3]
Length = 1059
Score = 75.9 bits (185), Expect = 3e-14
Identities = 39/96 (40%), Positives = 54/96 (56%)
Frame = +3
Query: 12 GQDTSRFLQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDG 191
G +R LQKAA+ ++S C R + V +CAG + SC GD+GGPL C +
Sbjct: 960 GGSMARQLQKAAVRLLSEQTCRRFYP-VQISSRMLCAGFPQGGVDSCSGDAGGPLACREP 1018
Query: 192 RKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWI 299
+ G+ S+G CG+P+ P VYTRV+ V GWI
Sbjct: 1019 SGRWVLTGVTSWG-YGCGRPHFPGVYTRVAAVRGWI 1053
Score = 69.7 bits (169), Expect = 2e-12
Identities = 37/89 (41%), Positives = 49/89 (55%)
Frame = +3
Query: 33 LQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQV 212
LQKA++ II C ++ N + ICAG SC+GDSGGPL C +
Sbjct: 645 LQKASVGIIDQKTCSVLY-NFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLA 703
Query: 213 GIVSYGTVPCGQPNVPSVYTRVSEVAGWI 299
GIVS+G + C Q P VYTR++ + GWI
Sbjct: 704 GIVSWG-IGCAQVKKPGVYTRITRLKGWI 731
Score = 62.0 bits (149), Expect = 4e-10
Identities = 32/89 (35%), Positives = 47/89 (52%)
Frame = +3
Query: 33 LQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQV 212
LQKA + ++ + C ++ + R +CAG SC+GDSGGPL C +
Sbjct: 345 LQKATVELLDQALCASLYGHSLTDRM-VCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLA 403
Query: 213 GIVSYGTVPCGQPNVPSVYTRVSEVAGWI 299
GIVS+G + C + P VY RV+ + WI
Sbjct: 404 GIVSWG-IGCAEARRPGVYARVTRLRDWI 431
>sp|P80420|TRYP_STREX Trypsin-like protease precursor
Length = 260
Score = 74.7 bits (182), Expect = 6e-14
Identities = 40/100 (40%), Positives = 55/100 (55%)
Frame = +3
Query: 12 GQDTSRFLQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDG 191
G R+L KA + +S++ C + + ICAG + +C+GDSGGP+F D
Sbjct: 159 GGGQQRYLLKANVPFVSDASCQSSYGSDLVPSEEICAGLPQGGVDTCQGDSGGPMFRRDN 218
Query: 192 RKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWIRANA 311
IQVGIVS+G C +PN P VYT VS A I++ A
Sbjct: 219 NNAWIQVGIVSWGE-GCARPNYPGVYTEVSTFAAAIKSAA 257
>sp|Q9UKR3|KLK13_HUMAN Kallikrein 13 precursor (Kallikrein-like protein 4) (KLK-L4)
Length = 277
Score = 74.3 bits (181), Expect = 8e-14
Identities = 41/98 (41%), Positives = 54/98 (55%)
Frame = +3
Query: 9 PGQDTSRFLQKAAINIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTD 188
P + + LQ A I + S+ EC +++ + +CAG+ SC GDSGGPL C
Sbjct: 168 PQVNYPKTLQCANIQLRSDEECRQVYPG-KITDNMLCAGTKEGGKDSCEGDSGGPLVC-- 224
Query: 189 GRKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWIR 302
+ GIVS+G PCGQP+ P VYTRVS WIR
Sbjct: 225 ---NRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIR 259
>sp|Q9I8X2|VSP1_AGKAC Acutobin precursor (Acuthrombin) (Acutase)
Length = 260
Score = 74.3 bits (181), Expect = 8e-14
Identities = 35/86 (40%), Positives = 53/86 (61%)
Frame = +3
Query: 48 INIISNSECGRIFSNVAYVRSNICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQVGIVSY 227
IN+++N+EC R + + +CAG + SC DSGGPL C DG+ G+V++
Sbjct: 168 INLVNNAECRRAYPRLPATSRTLCAGVMQGGIDSCNRDSGGPLIC-DGQFQ----GVVNW 222
Query: 228 GTVPCGQPNVPSVYTRVSEVAGWIRA 305
G PC QPN+P++YT+V + WIR+
Sbjct: 223 GGNPCAQPNMPALYTKVYDYNDWIRS 248
>sp|Q5U405|TMPSD_MOUSE Transmembrane protease, serine 13 (Mosaic serine protease)
(Membrane-type mosaic serine protease)
Length = 543
Score = 73.9 bits (180), Expect = 1e-13
Identities = 39/96 (40%), Positives = 56/96 (58%), Gaps = 1/96 (1%)
Frame = +3
Query: 15 QDTSRFLQKAAINIISNSECGRIFSNVAYVRSNI-CAGSGRLSTSSCRGDSGGPLFCTDG 191
+ TS FL++ +N+I +C +Y+ + CAG R SC+GDSGGPL C
Sbjct: 437 EKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQN 496
Query: 192 RKHHIQVGIVSYGTVPCGQPNVPSVYTRVSEVAGWI 299
+ ++ G+ S+GT CGQ N P VYT+V+EV WI
Sbjct: 497 NRWYL-AGVTSWGT-GCGQKNKPGVYTKVTEVLPWI 530
>sp|Q5QSK2|DESC4_RAT Serine protease DESC4 precursor [Contains: Serine protease DESC4
non-catalytic chain; Serine protease DESC4 catalytic
chain]
Length = 417
Score = 73.2 bits (178), Expect = 2e-13
Identities = 39/95 (41%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = +3
Query: 33 LQKAAINIISNSECGRIFSNVAYVRSN-ICAGSGRLSTSSCRGDSGGPLFCTDGRKHHIQ 209
LQ+ I IISN C ++ + S ICAG +C GDSGGPL +D R
Sbjct: 323 LQEVEIEIISNDVCNQVNVYGGAISSGMICAGFLTGKLDACEGDSGGPLVISDNRNKWYL 382
Query: 210 VGIVSYGTVPCGQPNVPSVYTRVSEVAGWIRANAN 314
+GIVS+G + CG+ N P +YTRV+ WI++ N
Sbjct: 383 LGIVSWG-IDCGKENKPGIYTRVTHYRNWIKSKTN 416
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,098,501
Number of Sequences: 369166
Number of extensions: 862225
Number of successful extensions: 3013
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2563
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2621
length of database: 68,354,980
effective HSP length: 87
effective length of database: 52,283,035
effective search space used: 1673057120
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)