Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_G06
(580 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P81021|VIGLN_CHICK Vigilin 100 3e-21
sp|Q00341|VIGLN_HUMAN Vigilin (High density lipoprotein-bin... 99 6e-21
sp|Q8VDJ3|VIGLN_MOUSE Vigilin (High density lipoprotein-bin... 98 1e-20
sp|Q9Z1A6|VIGLN_RAT Vigilin (High density lipoprotein-bindi... 96 6e-20
sp|P06105|SC160_YEAST Protein SCP160 (Protein HX) 39 0.007
sp|Q12114|CHS5_YEAST Chitin biosynthesis protein CHS5 (Prot... 36 0.079
sp|Q9PWD6|HXA10_MORSA Homeobox protein Hox-A10 35 0.10
sp|P31260|HXA10_HUMAN Homeobox protein Hox-A10 (Hox-1H) (Ho... 33 0.39
sp|Q64SM5|PSTB_BACFR Phosphate import ATP-binding protein p... 33 0.51
sp|Q8CAS9|BAL_MOUSE B aggressive lymphoma protein homolog 33 0.51
>sp|P81021|VIGLN_CHICK Vigilin
Length = 1270
Score = 100 bits (248), Expect = 3e-21
Identities = 67/184 (36%), Positives = 100/184 (54%), Gaps = 4/184 (2%)
Frame = +1
Query: 4 QKHHRILITRNMAEIKNIQNSFDVMIKFPNRDIS-SKSGENGYDEAHLNGNSDNTFVDTT 180
QK HR ++ + I+ I + V IKFP+R+ + + E E NG
Sbjct: 883 QKFHRSIMGPKGSRIQQITRDYGVQIKFPDREENPAPVAEPALQE---NGEEGG------ 933
Query: 181 EEGDSNVEAEQNNP--ANWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQK 354
EG +A+ ++P + + +SGRRE CE+AKEAL LVPV+ +V + + HR IGQK
Sbjct: 934 -EGKDGKDADPSSPRKCDIIIISGRREKCEAAKEALQALVPVTIEVEVPFDLHRYIIGQK 992
Query: 355 GQGINTFSTKYNVVVNIP-PANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIA 531
G GI ++ V + +P P + D I+I G ANL AKAGL E + + E++DR
Sbjct: 993 GSGIRKMMDEFEVNIQVPAPELQSSDIITITGLAANLDRAKAGLLERVKELQAEQEDRAL 1052
Query: 532 RNFE 543
R+F+
Sbjct: 1053 RSFK 1056
Score = 53.1 bits (126), Expect = 5e-07
Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 7/158 (4%)
Frame = +1
Query: 1 EQKHHRILITRNMAEIKNIQNSFDVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTT 180
+ K HR LI +N A I I++ + V ++ P
Sbjct: 442 DHKFHRHLIGKNGANINRIKDLYKVSVRIP------------------------------ 471
Query: 181 EEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELVPVSE-----DVPLNNEFHRNFI 345
N +N + + G + + AK+ LLEL E D+ + +FHR I
Sbjct: 472 ---------PDNEKSNLIRIEGDPQGVQQAKKELLELASRMENERTKDLIIEQKFHRTII 522
Query: 346 GQKGQGINTFSTKY-NVVVNIP-PANKCLDFISIKGPR 453
GQKG+ I K+ V++N P PA+K D + ++GP+
Sbjct: 523 GQKGERIREIREKFPEVIINFPDPAHKS-DIVQLRGPK 559
Score = 48.9 bits (115), Expect = 9e-06
Identities = 26/70 (37%), Positives = 39/70 (55%)
Frame = +1
Query: 307 DVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLD 486
++ ++++FHR+ IG+ G IN Y V V IPP N+ + I I+G + AK L
Sbjct: 438 EINVDHKFHRHLIGKNGANINRIKDLYKVSVRIPPDNEKSNLIRIEGDPQGVQQAKKELL 497
Query: 487 ELIVVWENEK 516
EL ENE+
Sbjct: 498 ELASRMENER 507
Score = 34.7 bits (78), Expect = 0.18
Identities = 33/143 (23%), Positives = 54/143 (37%), Gaps = 7/143 (4%)
Frame = +1
Query: 1 EQKHHRILITRNMAEIKNIQNSF-DVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDT 177
EQK HR +I + I+ I+ F +V+I FP D AH
Sbjct: 514 EQKFHRTIIGQKGERIREIREKFPEVIINFP-------------DPAH------------ 548
Query: 178 TEEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELVP------VSEDVPLNNEFHRN 339
++ V L G + E + + ++V S VP+ +FH+N
Sbjct: 549 --------------KSDIVQLRGPKNEVEKCTKYMQKMVADLVENSFSISVPIFKQFHKN 594
Query: 340 FIGQKGQGINTFSTKYNVVVNIP 408
IG+ G I + N +++P
Sbjct: 595 IIGKGGANIKKIREESNTKIDLP 617
Score = 32.3 bits (72), Expect = 0.87
Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 16/120 (13%)
Frame = +1
Query: 184 EGDSNVEAEQNNPANWVALSGRRENCESAKEALLELVPV----SED---------VPLNN 324
E + V A + ++ + ++G N + AK LLE V ED V ++
Sbjct: 1004 EVNIQVPAPELQSSDIITITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLTVTVDP 1063
Query: 325 EFHRNFIGQKGQGINTFSTKYNVVVNIP---PANKCLDFISIKGPRANLIDAKAGLDELI 495
++H IG+KG I T++ V + P ++ D I+I G N A+ + +++
Sbjct: 1064 KYHPKIIGRKGAVITQIRTEHEVNIQFPDKDDESQAQDQITITGYEKNAEAARDAIMKIV 1123
Score = 32.0 bits (71), Expect = 1.1
Identities = 22/95 (23%), Positives = 50/95 (52%), Gaps = 7/95 (7%)
Frame = +1
Query: 232 VALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHRNFIGQKGQGINTFSTKY-NV 393
+ + G E + A++ L L+ V + + ++ + HR+F+ ++GQ + + +Y V
Sbjct: 774 ITIMGTEEAVKEAQKELEALIKNLDNVVEDSMVVDPKHHRHFVIRRGQVLREIADEYGGV 833
Query: 394 VVNIPPANKC-LDFISIKGPRANLIDAKAGLDELI 495
+V +P + D +++KG + + AK + E+I
Sbjct: 834 MVRLPTVSGTQSDKVTLKGAKDCVEAAKKRIQEII 868
Score = 29.3 bits (64), Expect = 7.4
Identities = 13/46 (28%), Positives = 22/46 (47%)
Frame = +1
Query: 310 VPLNNEFHRNFIGQKGQGINTFSTKYNVVVNIPPANKCLDFISIKG 447
V + H+ IG+KG + K V V IPP + + + ++G
Sbjct: 299 VEVKKSQHKYVIGRKGNSLQEILEKTGVSVEIPPTDSSSETVILRG 344
>sp|Q00341|VIGLN_HUMAN Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 99.4 bits (246), Expect = 6e-21
Identities = 67/183 (36%), Positives = 99/183 (54%), Gaps = 3/183 (1%)
Frame = +1
Query: 4 QKHHRILITRNMAEIKNIQNSFDVMIKFPNRDISS-KSGENGYDEAHLNGNSDNTFVDTT 180
QK HR ++ + I+ I F V IKFP+R+ ++ S E E NG D
Sbjct: 882 QKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQE---NG-------DEA 931
Query: 181 EEGDSNVEAEQNNP--ANWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQK 354
EG + + +P + + +SGR+E CE+AKEAL LVPV+ +V + + HR IGQK
Sbjct: 932 GEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQK 991
Query: 355 GQGINTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIAR 534
G GI ++ V +++P D I+I G ANL AKAGL E + + E++DR R
Sbjct: 992 GSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALR 1051
Query: 535 NFE 543
+F+
Sbjct: 1052 SFK 1054
Score = 53.9 bits (128), Expect = 3e-07
Identities = 42/172 (24%), Positives = 70/172 (40%), Gaps = 9/172 (5%)
Frame = +1
Query: 1 EQKHHRILITRNMAEIKNIQNSFDVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTT 180
+ K+H +I R A I I+ DV I+FP++D
Sbjct: 1060 DPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKD--------------------------- 1092
Query: 181 EEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHRNFI 345
+ N P + + ++G +N E+A++A+L +V VSEDVPL++ H I
Sbjct: 1093 ---------DGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHARII 1143
Query: 346 GQKGQGINTFSTKYNVVVNIP----PANKCLDFISIKGPRANLIDAKAGLDE 489
G +G+ I ++ V + P P C+ + ID L+E
Sbjct: 1144 GARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEE 1195
Score = 50.1 bits (118), Expect = 4e-06
Identities = 38/134 (28%), Positives = 65/134 (48%)
Frame = +1
Query: 115 GENGYDEAHLNGNSDNTFVDTTEEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELV 294
G+ G + A + ++ TE G+ + E P V ++ +E E + L+ +
Sbjct: 381 GKKGQNLAKITQQMPKVHIEFTE-GEDKITLE--GPTEDVNVA--QEQIEGMVKDLINRM 435
Query: 295 PVSEDVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAK 474
E + ++++FHR+ IG+ G IN +Y V V IPP ++ + I I+G + AK
Sbjct: 436 DYVE-INIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAK 494
Query: 475 AGLDELIVVWENEK 516
L EL ENE+
Sbjct: 495 RELLELASRMENER 508
Score = 49.3 bits (116), Expect = 7e-06
Identities = 36/157 (22%), Positives = 61/157 (38%), Gaps = 6/157 (3%)
Frame = +1
Query: 1 EQKHHRILITRNMAEIKNIQNSFDVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTT 180
+ K HR LI ++ A I I++ + V ++ P
Sbjct: 443 DHKFHRHLIGKSGANINRIKDQYKVSVRIP------------------------------ 472
Query: 181 EEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELVPVSE-----DVPLNNEFHRNFI 345
+ +N + + G + + AK LLEL E D+ + FHR I
Sbjct: 473 ---------PDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTII 523
Query: 346 GQKGQGINTFSTKY-NVVVNIPPANKCLDFISIKGPR 453
GQKG+ I K+ V++N P + D + ++GP+
Sbjct: 524 GQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPK 560
Score = 49.3 bits (116), Expect = 7e-06
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 41/202 (20%)
Frame = +1
Query: 1 EQKHHRILITRNMAEIKNIQNSF-DVMIKFPN----RDISSKSG---------------- 117
EQ+ HR +I + I+ I++ F +V+I FP+ DI G
Sbjct: 515 EQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMV 574
Query: 118 ----ENGYD-------EAHLN--GNSDNTFVDTTEEGDSNVEAE-QNNPANWVALSGRRE 255
EN Y + H N G EE ++ ++ +N+ + + ++G+R
Sbjct: 575 ADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRA 634
Query: 256 NCESAKEALL----ELVPVSE-DVPLNNEFHRNFIGQKGQGINTFSTKY-NVVVNIPPAN 417
NCE+A+ +L +L ++E +V + + H + IG KG+ I + + V ++ P
Sbjct: 635 NCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEG 694
Query: 418 KCLDFISIKGPRANLIDAKAGL 483
D + I+GP +++ AK L
Sbjct: 695 SGSDTVVIRGPSSDVEKAKKQL 716
Score = 35.4 bits (80), Expect = 0.10
Identities = 22/103 (21%), Positives = 54/103 (52%), Gaps = 6/103 (5%)
Frame = +1
Query: 205 AEQNNPANWVALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHRNFIGQKGQGIN 369
A ++ + + + G+ + A++ L L+ V + + ++ + HR+F+ ++GQ +
Sbjct: 765 AAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLR 824
Query: 370 TFSTKY-NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELI 495
+ +Y V+V+ P + D +++KG + + AK + E+I
Sbjct: 825 EIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEII 867
Score = 30.8 bits (68), Expect = 2.5
Identities = 25/104 (24%), Positives = 45/104 (43%), Gaps = 16/104 (15%)
Frame = +1
Query: 232 VALSGRRENCESAKEALLELVPVSE-------------DVPLNNEFHRNFIGQKGQGINT 372
+A++G N + AK LLE V + V ++ ++H IG+KG I
Sbjct: 1018 IAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQ 1077
Query: 373 FSTKYNVVVNIP---PANKCLDFISIKGPRANLIDAKAGLDELI 495
+++V + P N+ D I+I G N A+ + ++
Sbjct: 1078 IRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIV 1121
>sp|Q8VDJ3|VIGLN_MOUSE Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 98.2 bits (243), Expect = 1e-20
Identities = 66/183 (36%), Positives = 99/183 (54%), Gaps = 3/183 (1%)
Frame = +1
Query: 4 QKHHRILITRNMAEIKNIQNSFDVMIKFPNRDISS-KSGENGYDEAHLNGNSDNTFVDTT 180
QK HR ++ + I+ I ++V IKFP+R+ + S E E NG D
Sbjct: 882 QKFHRSVMGPKGSRIQQITRDYNVQIKFPDREENPVHSVEPSIQE---NG-------DEA 931
Query: 181 EEGDSNVEAEQNNP--ANWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQK 354
EG E + +P + + +SGR+E CE+AKEAL LVPV+ +V + + HR IGQK
Sbjct: 932 GEGREAKETDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYIIGQK 991
Query: 355 GQGINTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIAR 534
G GI ++ V +++P D I+I G ANL AKAGL + + + E++DR R
Sbjct: 992 GSGIRKMMDEFEVNIHVPAPELQSDTIAITGLAANLDRAKAGLLDRVKELQAEQEDRALR 1051
Query: 535 NFE 543
+F+
Sbjct: 1052 SFK 1054
Score = 52.8 bits (125), Expect = 6e-07
Identities = 41/172 (23%), Positives = 71/172 (41%), Gaps = 9/172 (5%)
Frame = +1
Query: 1 EQKHHRILITRNMAEIKNIQNSFDVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTT 180
+ K+H +I R A I I+ +V I+FP++D
Sbjct: 1060 DPKYHPKIIGRKGAVITQIRLEHEVNIQFPDKD--------------------------- 1092
Query: 181 EEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHRNFI 345
+ N P + + ++G +N E+A++A+L++V VSEDVPL++ H I
Sbjct: 1093 ---------DGNQPQDQITITGYEKNTEAARDAILKIVGELEQMVSEDVPLDHRVHARII 1143
Query: 346 GQKGQGINTFSTKYNVVVNIP----PANKCLDFISIKGPRANLIDAKAGLDE 489
G +G+ I ++ V + P P C+ + ID L+E
Sbjct: 1144 GARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEE 1195
Score = 50.1 bits (118), Expect = 4e-06
Identities = 38/134 (28%), Positives = 65/134 (48%)
Frame = +1
Query: 115 GENGYDEAHLNGNSDNTFVDTTEEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELV 294
G+ G + A + ++ TE G+ + E P V ++ +E E + L+ +
Sbjct: 381 GKKGQNLAKITQQMPKVHIEFTE-GEDKITLE--GPTEDVNVA--QEQIEGMVKDLINRM 435
Query: 295 PVSEDVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAK 474
E + ++++FHR+ IG+ G IN +Y V V IPP ++ + I I+G + AK
Sbjct: 436 DYVE-INIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAK 494
Query: 475 AGLDELIVVWENEK 516
L EL ENE+
Sbjct: 495 RELLELASRMENER 508
Score = 49.3 bits (116), Expect = 7e-06
Identities = 36/157 (22%), Positives = 61/157 (38%), Gaps = 6/157 (3%)
Frame = +1
Query: 1 EQKHHRILITRNMAEIKNIQNSFDVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTT 180
+ K HR LI ++ A I I++ + V ++ P
Sbjct: 443 DHKFHRHLIGKSGANINRIKDQYKVSVRIP------------------------------ 472
Query: 181 EEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELVPVSE-----DVPLNNEFHRNFI 345
+ +N + + G + + AK LLEL E D+ + FHR I
Sbjct: 473 ---------PDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTII 523
Query: 346 GQKGQGINTFSTKY-NVVVNIPPANKCLDFISIKGPR 453
GQKG+ I K+ V++N P + D + ++GP+
Sbjct: 524 GQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPK 560
Score = 49.3 bits (116), Expect = 7e-06
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 41/202 (20%)
Frame = +1
Query: 1 EQKHHRILITRNMAEIKNIQNSF-DVMIKFPN----RDISSKSG---------------- 117
EQ+ HR +I + I+ I++ F +V+I FP+ DI G
Sbjct: 515 EQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMV 574
Query: 118 ----ENGYD-------EAHLN--GNSDNTFVDTTEEGDSNVEAE-QNNPANWVALSGRRE 255
EN Y + H N G EE ++ ++ +N+ + + ++G+R
Sbjct: 575 ADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRA 634
Query: 256 NCESAKEALL----ELVPVSE-DVPLNNEFHRNFIGQKGQGINTFSTKY-NVVVNIPPAN 417
NCE+A+ +L +L ++E +V + + H + IG KG+ I + + V ++ P
Sbjct: 635 NCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEG 694
Query: 418 KCLDFISIKGPRANLIDAKAGL 483
D + I+GP +++ AK L
Sbjct: 695 SGSDTVVIRGPSSDVEKAKKQL 716
Score = 37.7 bits (86), Expect = 0.021
Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 5/64 (7%)
Frame = +1
Query: 232 VALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHRNFIGQKGQGINTFSTKYNVV 396
V L G ++ E+AK+ + E++ V+ + + +FHR+ +G KG I + YNV
Sbjct: 847 VTLKGAKDCVEAAKKRIQEIIEDLEAQVTVECAIPQKFHRSVMGPKGSRIQQITRDYNVQ 906
Query: 397 VNIP 408
+ P
Sbjct: 907 IKFP 910
Score = 35.0 bits (79), Expect = 0.13
Identities = 23/103 (22%), Positives = 54/103 (52%), Gaps = 6/103 (5%)
Frame = +1
Query: 205 AEQNNPANWVALSGRRENCESAKEALLELVPVSEDVP-----LNNEFHRNFIGQKGQGIN 369
A ++ + + + G+ + A++ L L+ E+V ++ + HR+F+ ++GQ +
Sbjct: 765 AAEDKDQDLITIIGKEDAVREAQKELEALIQNLENVVEDYMLVDPKHHRHFVIRRGQVLR 824
Query: 370 TFSTKY-NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELI 495
+ +Y V+V+ P + D +++KG + + AK + E+I
Sbjct: 825 EIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEII 867
Score = 31.6 bits (70), Expect = 1.5
Identities = 23/98 (23%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 232 VALSGRRENCESAKEALLELVPV--SEDVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNI 405
+ +SG+ + A++ ++ + S VP+ E HR IG+ G+ + K + I
Sbjct: 127 IMVSGKLDAVMKARKDIVARLQTQASATVPIPKEHHRFVIGKNGEKLQDLELKTATKIQI 186
Query: 406 PPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQ 519
P + + I I G + + KA + L++ E +K+
Sbjct: 187 PRPDDPSNQIKITGTKEGI--EKARHEVLLISAEQDKR 222
Score = 30.8 bits (68), Expect = 2.5
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 16/104 (15%)
Frame = +1
Query: 232 VALSGRRENCESAKEALL----ELVPVSED---------VPLNNEFHRNFIGQKGQGINT 372
+A++G N + AK LL EL ED V ++ ++H IG+KG I
Sbjct: 1018 IAITGLAANLDRAKAGLLDRVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQ 1077
Query: 373 FSTKYNVVVNIP---PANKCLDFISIKGPRANLIDAKAGLDELI 495
++ V + P N+ D I+I G N A+ + +++
Sbjct: 1078 IRLEHEVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILKIV 1121
>sp|Q9Z1A6|VIGLN_RAT Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 95.9 bits (237), Expect = 6e-20
Identities = 65/183 (35%), Positives = 98/183 (53%), Gaps = 3/183 (1%)
Frame = +1
Query: 4 QKHHRILITRNMAEIKNIQNSFDVMIKFPNRDISS-KSGENGYDEAHLNGNSDNTFVDTT 180
QK HR ++ + I+ I ++V IKFP+R+ + S E E NG D
Sbjct: 882 QKFHRSVMGPKGSRIQQITRDYNVQIKFPDREENPVHSVEPSIQE---NG-------DEA 931
Query: 181 EEGDSNVEAEQNNP--ANWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQK 354
EG E + +P + + +SGR+E CE+AKEAL LVPV+ +V + + HR IGQK
Sbjct: 932 GEGREAKETDPGSPRRCDIIVISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYIIGQK 991
Query: 355 GQGINTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIAR 534
G GI ++ V +++P I+I G ANL AKAGL + + + E++DR R
Sbjct: 992 GSGIRKMMDEFEVNIHVPAPELQSHTIAITGLAANLDRAKAGLLDRVKELQAEQEDRALR 1051
Query: 535 NFE 543
+F+
Sbjct: 1052 SFK 1054
Score = 51.6 bits (122), Expect = 1e-06
Identities = 41/172 (23%), Positives = 70/172 (40%), Gaps = 9/172 (5%)
Frame = +1
Query: 1 EQKHHRILITRNMAEIKNIQNSFDVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTT 180
+ K+H +I A I I+ DV I+FP++D
Sbjct: 1060 DPKYHPKIIGGKGAVITQIRLEHDVNIQFPDKD--------------------------- 1092
Query: 181 EEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHRNFI 345
+ N P + + ++G +N E+A++A+L++V VSEDVPL++ H I
Sbjct: 1093 ---------DGNQPQDQITITGYEKNTEAARDAILKIVGELEQMVSEDVPLDHRVHARII 1143
Query: 346 GQKGQGINTFSTKYNVVVNIP----PANKCLDFISIKGPRANLIDAKAGLDE 489
G +G+ I ++ V + P P C+ + ID L+E
Sbjct: 1144 GARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEE 1195
Score = 50.1 bits (118), Expect = 4e-06
Identities = 38/134 (28%), Positives = 65/134 (48%)
Frame = +1
Query: 115 GENGYDEAHLNGNSDNTFVDTTEEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELV 294
G+ G + A + ++ TE G+ + E P V ++ +E E + L+ +
Sbjct: 381 GKKGQNLAKITHQMPKVHIEFTE-GEDKITLE--GPTEDVNVA--QEQIEGMVKDLINRM 435
Query: 295 PVSEDVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAK 474
E + ++++FHR+ IG+ G IN +Y V V IPP ++ + I I+G + AK
Sbjct: 436 DYVE-INIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAK 494
Query: 475 AGLDELIVVWENEK 516
L EL ENE+
Sbjct: 495 RELLELASRMENER 508
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/202 (23%), Positives = 90/202 (44%), Gaps = 41/202 (20%)
Frame = +1
Query: 1 EQKHHRILITRNMAEIKNIQNSF-DVMIKFPN----RDISSKSG---------------- 117
EQ+ HR +I + I+ I++ F +V+I FP+ +I G
Sbjct: 515 EQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSEIVQLRGPKNEVEKCTKYMQKMV 574
Query: 118 ----ENGYD-------EAHLN--GNSDNTFVDTTEEGDSNVEAE-QNNPANWVALSGRRE 255
EN Y + H N G EE ++ ++ +N+ + + ++G+R
Sbjct: 575 ADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSETIVITGKRA 634
Query: 256 NCESAKEALL----ELVPVSE-DVPLNNEFHRNFIGQKGQGINTFSTKY-NVVVNIPPAN 417
NCE+A+ +L +L ++E +V + + H + IG KG+ I + + V ++ P
Sbjct: 635 NCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEG 694
Query: 418 KCLDFISIKGPRANLIDAKAGL 483
D + I+GP +++ AK L
Sbjct: 695 SGSDTVVIRGPSSDVEKAKKQL 716
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/157 (22%), Positives = 61/157 (38%), Gaps = 6/157 (3%)
Frame = +1
Query: 1 EQKHHRILITRNMAEIKNIQNSFDVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTT 180
+ K HR LI ++ A I I++ + V ++ P
Sbjct: 443 DHKFHRHLIGKSGANINRIKDQYKVSVRIP------------------------------ 472
Query: 181 EEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELVPVSE-----DVPLNNEFHRNFI 345
+ +N + + G + + AK LLEL E D+ + FHR I
Sbjct: 473 ---------PDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTII 523
Query: 346 GQKGQGINTFSTKY-NVVVNIPPANKCLDFISIKGPR 453
GQKG+ I K+ V++N P + + + ++GP+
Sbjct: 524 GQKGERIREIRDKFPEVIINFPDPAQKSEIVQLRGPK 560
Score = 37.4 bits (85), Expect = 0.027
Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 5/64 (7%)
Frame = +1
Query: 232 VALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHRNFIGQKGQGINTFSTKYNVV 396
V L G ++ E+AK+ + E++ V+ + + +FHR+ +G KG I + YNV
Sbjct: 847 VTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQITRDYNVQ 906
Query: 397 VNIP 408
+ P
Sbjct: 907 IKFP 910
Score = 32.0 bits (71), Expect = 1.1
Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 2/111 (1%)
Frame = +1
Query: 232 VALSGRRENCESAKEALLELVPV--SEDVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNI 405
+ +SG+ + A++ ++ + S VP+ E HR IG+ G+ + K + I
Sbjct: 127 IMVSGKLDAVMKARKDIVARLQTQASATVPIPKEHHRFVIGKNGEKLQDLELKTATKIQI 186
Query: 406 PPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQSLF 558
P + + I I G + + KA + L++ E +K R + E + F
Sbjct: 187 PRPDDPSNQIKITGTKEGI--EKARHEVLLISAEQDK--RAVKRLEVEKAF 233
>sp|P06105|SC160_YEAST Protein SCP160 (Protein HX)
Length = 1222
Score = 39.3 bits (90), Expect = 0.007
Identities = 35/132 (26%), Positives = 58/132 (43%), Gaps = 12/132 (9%)
Frame = +1
Query: 136 AHLNGNSDNTFVDTTEEGDSNVEA--EQNNPANW-----VALSGRRENCESAKEALLELV 294
A L GN + E+ ++ E+NN A+ V L+G N AK+ L
Sbjct: 647 ARLIGNKGSNLQQIREKFACQIDIPNEENNNASKDKTVEVTLTGLEYNLTHAKKYLAAEA 706
Query: 295 P-----VSEDVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNIPPANKCLDFISIKGPRAN 459
+++++ + +FH + IG G N KYNV +N P N + ++I+GP
Sbjct: 707 KKWADIITKELIVPVKFHGSLIGPHGTYRNRLQEKYNVFINFPRDN---EIVTIRGPSRG 763
Query: 460 LIDAKAGLDELI 495
+ A L L+
Sbjct: 764 VNKAHEELKALL 775
>sp|Q12114|CHS5_YEAST Chitin biosynthesis protein CHS5 (Protein CAL3)
Length = 671
Score = 35.8 bits (81), Expect = 0.079
Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
Frame = +1
Query: 28 TRNMAEIKNIQNSFDVMIKFPNRDISSKS------GENGYD-EAHLNGNSDNTFVDTTEE 186
T N+ E K +S + +++ PN ++ S G+ D + H N +DN FV T E
Sbjct: 373 TPNIEENK-ADSSAEAVVEEPNEAVAESSPNEEATGQKSEDTDTHSNEQADNGFVQTEEV 431
Query: 187 GDSNV----EAEQNNPANWVALSGRRENCESAKEALLELVPVSEDVPLNNE 327
++N+ E N PA+ A+ R EA +E V+E + NE
Sbjct: 432 AENNITTESAGENNEPADDAAMEFGR------PEAEIETPEVNESIEDANE 476
>sp|Q9PWD6|HXA10_MORSA Homeobox protein Hox-A10
Length = 289
Score = 35.4 bits (80), Expect = 0.10
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 8/64 (12%)
Frame = +1
Query: 124 GYDEAHLNGNSDNTFVDTTEEGDSNVEAEQN-------NPANWV-ALSGRRENCESAKEA 279
G +EA + +++ + D TEE D +A+ N ANW+ A SGR++ C K
Sbjct: 167 GTEEARESSDAEVSSADETEEHDKERQAKSTKGDTKSENTANWLTAKSGRKKRCPYTKHQ 226
Query: 280 LLEL 291
LEL
Sbjct: 227 TLEL 230
>sp|P31260|HXA10_HUMAN Homeobox protein Hox-A10 (Hox-1H) (Hox-1.8) (PL)
Length = 393
Score = 33.5 bits (75), Expect = 0.39
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Frame = +1
Query: 88 PNRDISSKSGENGYDEAHLNGNSDNTFVDTTEEG-------DSNVEAEQNNPANWV-ALS 243
P S G G +EAH + ++ E DS ++ N ANW+ A S
Sbjct: 259 PTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSLGNSKGENAANWLTAKS 318
Query: 244 GRRENCESAKEALLEL 291
GR++ C K LEL
Sbjct: 319 GRKKRCPYTKHQTLEL 334
>sp|Q64SM5|PSTB_BACFR Phosphate import ATP-binding protein pstB (Phosphate-transporting
ATPase) (ABC phosphate transporter)
Length = 253
Score = 33.1 bits (74), Expect = 0.51
Identities = 24/80 (30%), Positives = 36/80 (45%)
Frame = +1
Query: 340 FIGQKGQGINTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQ 519
FIG G G +TF +N + ++ PA + I I G N+ D +DEL +
Sbjct: 37 FIGPSGCGKSTFLRLFNRMNDLIPATRLTGEIRIDG--ENIYDKGVQVDEL--------R 86
Query: 520 DRIARNFENQSLFPSSFIEN 579
+ F+ + FP S EN
Sbjct: 87 KNVGMVFQRPNPFPKSIFEN 106
>sp|Q8CAS9|BAL_MOUSE B aggressive lymphoma protein homolog
Length = 866
Score = 33.1 bits (74), Expect = 0.51
Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 5/141 (3%)
Frame = +1
Query: 130 DEAHLNGNSDNTFVDTTEEGDSNVEAEQNNPANWVALSGRR--ENCESAKEALLELVPVS 303
+E +L+GNS + + E +PA + L G + E CE+ + LV +
Sbjct: 493 NELNLSGNSGALALQWSSGEQRRGGLEAGSPA--INLMGVKVGEMCEAQEWIERLLVSLD 550
Query: 304 EDVPLNNEFHRNFIGQKGQGINT---FSTKYNVVVNIPPANKCLDFISIKGPRANLIDAK 474
+ NN H ++G+K + + ST+ ++ + P L+ IKGP+A+LIDA
Sbjct: 551 HHIIENN--HILYLGKKEHDVLSELQTSTRVSISETVSPRTATLE---IKGPQADLIDAV 605
Query: 475 AGLDELIVVWENEKQDRIARN 537
++ ++ + E + +N
Sbjct: 606 MRIECMLCDVQEEVAGKREKN 626
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.313 0.131 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,950,653
Number of Sequences: 369166
Number of extensions: 1400324
Number of successful extensions: 2917
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2765
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2883
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4259329035
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)