Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_F18
(838 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P64759|Y906_MYCTU Hypothetical protein Rv0906/MT0929 pre... 149 9e-36
sp|Q8TV58|YF42_METKA Hypothetical UPF0173 metal-dependent h... 60 7e-09
sp|Q48412|ROMA_KLEPN Outer membrane protein romA 59 1e-08
sp|Q9YCZ5|Y1117_AERPE Hypothetical UPF0173 metal-dependent ... 59 1e-08
sp|Q8PUN2|YN00_METMA Hypothetical UPF0173 metal-dependent h... 46 1e-04
sp|Q8TR74|YD08_METAC Hypothetical UPF0173 metal-dependent h... 46 1e-04
sp|Q9X0P5|YB62_THEMA Hypothetical UPF0173 metal-dependent h... 44 6e-04
sp|P95962|Y099_SULSO Hypothetical UPF0173 metal-dependent h... 40 0.006
sp|Q9V1C7|Y500_PYRAB Hypothetical UPF0173 metal-dependent h... 40 0.008
sp|Q8U053|YH64_PYRFU Hypothetical UPF0173 metal-dependent h... 40 0.008
>sp|P64759|Y906_MYCTU Hypothetical protein Rv0906/MT0929 precursor
sp|P64760|Y930_MYCBO Hypothetical protein Mb0930 precursor
Length = 372
Score = 149 bits (376), Expect = 9e-36
Identities = 87/229 (37%), Positives = 129/229 (56%), Gaps = 2/229 (0%)
Frame = +1
Query: 157 LPIVQPNFNYKSRPETYNIVVTWLGHASILLEIEGFKILCDPIFSKTCGPFG--GIKRFQ 330
+P+ PN R + + V+W GH++ LLEI+G+++L DP++S C P G +R
Sbjct: 90 IPLASPNIY---RGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLH 146
Query: 331 DAPCKIEDLPDIDAVVISHNHYDHMDAETIKELSKKYKTLKWCIPDGDRHNLCSMIEGNI 510
P ++ LP +DAVVISH+HYDH+D +T+ L + + +P G +L S G
Sbjct: 147 PPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRA-PFLVPLGVGAHLRSW--GVP 203
Query: 511 NEDINEMKWWDELEIVKHERKLKVVFTPTQHWSNRGLLDAFKSLWGSYAFVGENNKFWFG 690
+ I E+ W ++ +L VV P +H+S R L +LW S+AFVG N++ +FG
Sbjct: 204 QDRIVELDWNQSAQV----DELTVVCVPARHFSGR-FLSRNTTLWASWAFVGPNHRAYFG 258
Query: 691 GDTGYCPAFKQIGKKYGPFTGAAIPIGAYKPRDFLKFQHCDPNEAVQIH 837
GDTGY +F QIG +GPF +PIGAY H +P EAV+ H
Sbjct: 259 GDTGYTKSFTQIGADHGPFDLTLLPIGAYNTA--WPDIHMNPEEAVRAH 305
>sp|Q8TV58|YF42_METKA Hypothetical UPF0173 metal-dependent hydrolase MK1542
Length = 230
Score = 60.1 bits (144), Expect = 7e-09
Identities = 56/215 (26%), Positives = 92/215 (42%), Gaps = 8/215 (3%)
Frame = +1
Query: 217 VTWLGHASILLEIEGFKILCDPIFSKTCGPFGGIKRFQDAPCKIEDLPDIDAVVISHNHY 396
+TWLGHA+ +EI+G +L DP S G K K D D D V+++H H
Sbjct: 3 ITWLGHAAFEVEIDGVNVLIDPFLS------GNPK-----AAKSPDEVDPDLVLVTHGHG 51
Query: 397 DHMDAETIKELSKKYKTLKWCIPDGDRHNLCSMIEGNINEDINEMKWWDELEIVKHERKL 576
DH+ + ++ + TL + + +G E++ EM +E+ E
Sbjct: 52 DHL-GDAVEICKRTGATLVGI------YEIAVYAQGQGVENVEEMNIGGTIEVEGLE--- 101
Query: 577 KVVFTPTQHWSNRGLLDAFKSLWG----SYAFVGENNKFWFGGDTGYCPAFKQIGKKYGP 744
T W + +++ + + G Y GE + GDTG K IG+ Y P
Sbjct: 102 ---ITQVPAWHSSEIVEDGEIVAGGTPVGYVVSGEEGSVYHAGDTGLSMDMKLIGELYEP 158
Query: 745 FTGAAIPIGA---YKPRDFLK-FQHCDPNEAVQIH 837
A +PIG+ P++ K + +P A+ +H
Sbjct: 159 EV-ALLPIGSRFTMGPKEAAKAVELIEPEVAIPMH 192
>sp|Q48412|ROMA_KLEPN Outer membrane protein romA
Length = 132
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/87 (39%), Positives = 50/87 (57%)
Frame = +1
Query: 571 KLKVVFTPTQHWSNRGLLDAFKSLWGSYAFVGENNKFWFGGDTGYCPAFKQIGKKYGPFT 750
+L V P +H+S RGL ++LW S+ FV K ++ GD+GY P FK IG ++GP
Sbjct: 6 QLTVHVLPARHFSGRGL-KRNQTLWASFLFVTPQQKIYYSGDSGYGPHFKAIGDEFGPVD 64
Query: 751 GAAIPIGAYKPRDFLKFQHCDPNEAVQ 831
A + G Y +D+ K+ H P+E Q
Sbjct: 65 LAIMENGQY-DQDW-KYIHMMPDETAQ 89
>sp|Q9YCZ5|Y1117_AERPE Hypothetical UPF0173 metal-dependent hydrolase APE1117
Length = 242
Score = 59.3 bits (142), Expect = 1e-08
Identities = 58/205 (28%), Positives = 88/205 (42%), Gaps = 14/205 (6%)
Frame = +1
Query: 217 VTWLGHASILLEIEGFKILCDPIFSKTCGPFGGIKRFQDAPCKIEDLPDIDAVVISHNHY 396
+T+LGHA+ LE G KIL DP S +P K E++ +D +VI+H+H+
Sbjct: 4 LTYLGHAAFQLEAGGRKILVDPWLSNP-----------KSPVKPEEVEGVDLIVITHSHF 52
Query: 397 DHM-DAETIKELSKKYKTLKWCIPDGDRHNLCSMIEGNINEDINEMKWWDEL-------- 549
DH+ D I + K L + + + I ++ K DEL
Sbjct: 53 DHLGDVGKIAAKNPGAKVLA-------VYEVADLAAEEIAKETGASK--DELFNAGRVIG 103
Query: 550 -----EIVKHERKLKVVFTPTQHWSNRGLLDAFKSLWGSYAFVGENNKFWFGGDTGYCPA 714
+V + LKV FTP H S+ G+ G+ GE + + GDTG
Sbjct: 104 ANIGGPVVLQDLGLKVAFTPATH-SSVGVAA------GAVIITGE-GRVYHAGDTGVTMD 155
Query: 715 FKQIGKKYGPFTGAAIPIGAYKPRD 789
+ +G+ Y P A +PIG + D
Sbjct: 156 MRLVGEIYKPHV-ALLPIGGHFTMD 179
>sp|Q8PUN2|YN00_METMA Hypothetical UPF0173 metal-dependent hydrolase MM2300
Length = 230
Score = 46.2 bits (108), Expect = 1e-04
Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 1/67 (1%)
Frame = +1
Query: 208 NIVVTWLGHASILLEIEGFKILCDPIFSKTCGPFGGIKRFQDAPCKIEDL-PDIDAVVIS 384
++ +TWLGHA+ LLE E K+L DP S+ +PC EDL PDI + ++
Sbjct: 3 DLKITWLGHAAFLLESEK-KLLIDPFISEN----------PKSPCSPEDLNPDI--IAVT 49
Query: 385 HNHYDHM 405
H H DH+
Sbjct: 50 HGHRDHL 56
>sp|Q8TR74|YD08_METAC Hypothetical UPF0173 metal-dependent hydrolase MA1308
Length = 230
Score = 45.8 bits (107), Expect = 1e-04
Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 1/67 (1%)
Frame = +1
Query: 208 NIVVTWLGHASILLEIEGFKILCDPIFSKTCGPFGGIKRFQDAPCKIEDL-PDIDAVVIS 384
++ +TWLGHA+ LLE E K+L DP S+ APC E+L PDI + ++
Sbjct: 3 DLKITWLGHAAFLLEAEK-KLLIDPFISEN----------PKAPCTPEELNPDI--IAVT 49
Query: 385 HNHYDHM 405
H H DH+
Sbjct: 50 HGHRDHL 56
>sp|Q9X0P5|YB62_THEMA Hypothetical UPF0173 metal-dependent hydrolase TM1162
Length = 226
Score = 43.9 bits (102), Expect = 6e-04
Identities = 44/176 (25%), Positives = 67/176 (38%), Gaps = 14/176 (7%)
Frame = +1
Query: 217 VTWLGHASILLEIEGFK-ILCDPIFSKTCGPFGGIKRFQDAPCKIEDLPDIDAVVISHNH 393
VT+LGHA +L IEG K I+ DP S P K+E LP ID ++++H H
Sbjct: 3 VTFLGHAVVL--IEGKKNIIIDPFISGN----------PVCPVKLEGLPKIDYILVTHGH 50
Query: 394 YDHMDAETIKELSKKYKTLKWCIPDGDRHNLCSMIEGNINEDINEMKWWDELEIVKHERK 573
DH+ GD + + + + + + + H
Sbjct: 51 GDHL---------------------GDAVEIAKKNDATVISNYEICHYLGKKGVKTHAMH 89
Query: 574 L---------KVVFTPTQHWSNRGLLDAFKSLWG----SYAFVGENNKFWFGGDTG 702
+ +V TP H S G+LD ++G + E K + GDTG
Sbjct: 90 IGGSYLFDFGRVKMTPAVHGS--GILDGDSMIYGGNPSGFLITIEGKKIYHAGDTG 143
>sp|P95962|Y099_SULSO Hypothetical UPF0173 metal-dependent hydrolase SSO0099
Length = 227
Score = 40.4 bits (93), Expect = 0.006
Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +1
Query: 223 WLGHASILLEIEGFKILCDPIFSKTCGPFGGIKRFQDAPCKIEDLPD-IDAVVISHNHYD 399
WLGHA+ LL ++ DP+ IK +P K++ + +D ++++H+HYD
Sbjct: 6 WLGHAATLLTFGNKNVIIDPM----------IKDNPLSPVKLDYFKNNLDIIIVTHDHYD 55
Query: 400 HMDAETIKELSKKYKTLKWCIPDGDRH 480
H+ +T++ L K + D + H
Sbjct: 56 HL-GDTVELLRMNPKAKLFATYDLEAH 81
>sp|Q9V1C7|Y500_PYRAB Hypothetical UPF0173 metal-dependent hydrolase PYRAB05000
Length = 225
Score = 40.0 bits (92), Expect = 0.008
Identities = 47/192 (24%), Positives = 77/192 (40%), Gaps = 3/192 (1%)
Frame = +1
Query: 211 IVVTWLGHASILLEIEGFKILCDPIFSKTCGPFGGIKRFQDAPCKIEDLPDIDAVVISHN 390
+ V +LGHA+ +E KIL DP + A K ED D+D ++++H
Sbjct: 2 VKVKFLGHAAFYIE-GSKKILIDPFLTGN----------PQAVAKPEDFKDVDLILVTHA 50
Query: 391 HYDHM-DAETIKELSKKYKTLKWCIPDGDRHNLCSMIEGNINEDINEMKWWDELEIVKHE 567
H DH+ DA I ++S + I + + +N E+ D + IV+
Sbjct: 51 HGDHIGDAGEIAKISGAKIVAMYDIANYIAEKFKGVETVGMNYGPTEV---DGVFIVQ-- 105
Query: 568 RKLKVVFTPTQHWSNRGLLDAFKSLWGSYAFVG--ENNKFWFGGDTGYCPAFKQIGKKYG 741
P H S+ D S+ + F+ + + GDT + + YG
Sbjct: 106 -------VPAWHSSS----DGKYSIGNASGFIVKLDGKTIYHAGDTYVFKDMELFSELYG 154
Query: 742 PFTGAAIPIGAY 777
P A +PIG +
Sbjct: 155 PIDVALLPIGGH 166
>sp|Q8U053|YH64_PYRFU Hypothetical UPF0173 metal-dependent hydrolase PF1764
Length = 225
Score = 40.0 bits (92), Expect = 0.008
Identities = 45/190 (23%), Positives = 75/190 (39%), Gaps = 1/190 (0%)
Frame = +1
Query: 211 IVVTWLGHASILLEIEGFKILCDPIFSKTCGPFGGIKRFQDAPCKIEDLPDIDAVVISHN 390
+ VT+LGHA+ +E KIL DP S A K +D +D ++++H
Sbjct: 2 VKVTFLGHAAFYIE-GSKKILIDPFLSGN----------PVASAKPDDFKSVDLILVTHA 50
Query: 391 HYDHM-DAETIKELSKKYKTLKWCIPDGDRHNLCSMIEGNINEDINEMKWWDELEIVKHE 567
H DH+ D TI + + + + + + +N ++ DE+EIV+
Sbjct: 51 HGDHLGDVGTIAKRTGAKVVAMYDLANYIAEKYKGVETIGMNYGPTKV---DEVEIVQ-- 105
Query: 568 RKLKVVFTPTQHWSNRGLLDAFKSLWGSYAFVGENNKFWFGGDTGYCPAFKQIGKKYGPF 747
P H S+ G + Y + + GDT + + YGP
Sbjct: 106 -------VPAWHSSSDGKYSIGNAC--GYIVKLDGVTIYHAGDTYVFKDMELFAELYGPI 156
Query: 748 TGAAIPIGAY 777
A +PIG +
Sbjct: 157 DVALLPIGGH 166
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 104,192,114
Number of Sequences: 369166
Number of extensions: 2318624
Number of successful extensions: 6449
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6196
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6419
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8148988185
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)