Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_E12
(982 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53990|K0174_HUMAN Protein KIAA0174 (Putative MAPK-activ... 214 2e-55
sp|P53843|YN05_YEAST Hypothetical 34.5 kDa protein in PIK1-... 92 3e-18
sp|Q9ULJ6|ZIM10_HUMAN Retinoic acid-induced protein 17 (PIA... 36 0.15
sp|Q12446|LAS17_YEAST Proline-rich protein LAS17 35 0.42
sp|O43313|Y0431_HUMAN Hypothetical protein KIAA0431 34 0.55
sp|Q6UB99|ANR11_HUMAN Ankyrin repeat domain protein 11 (Ank... 33 1.6
sp|Q8CI61|BAG4_MOUSE BAG-family molecular chaperone regulat... 31 4.7
sp|O95466|FMNL_HUMAN Formin-like 1 protein (Formin-like pro... 31 4.7
sp|Q6P1E1|ZIM10_MOUSE Retinoic acid-induced protein 17 (PIA... 31 4.7
sp|Q8CHI5|PER1_RAT Period circadian protein 1 (rPER1) 31 4.7
>sp|P53990|K0174_HUMAN Protein KIAA0174 (Putative MAPK-activating protein PM28)
Length = 364
Score = 214 bits (546), Expect = 2e-55
Identities = 130/315 (41%), Positives = 176/315 (55%), Gaps = 35/315 (11%)
Frame = +3
Query: 3 LKLLEKKNTEIALKSRKEIADYLTSAKYDRARIKVEMIIRQDYLVEVYELIEMFCDLLLA 182
LKLLEKK TE+A K+RKEIADYL + K +RARI+VE IIR+DYLVE E++E++CDLLLA
Sbjct: 22 LKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLA 81
Query: 183 RFGLIECQKEIDPGLEEQIATLIWVTPRLQTDVQELKLITDQLHLKYGREYGLACQSNSL 362
RFGLI+ KE+D GL E ++TLIW PRLQ++V ELK++ DQL KY +EYG C++N +
Sbjct: 82 RFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQI 141
Query: 363 NNVNEKVMEKLSIKAPPKRLVEQYLVEIAKSFDVPYEPEEDIDPPASNWNPGEFYAPLPP 542
VN+++M KLS++APPK LVE+YL+EIAK+++VPYEP+ + A PG +
Sbjct: 142 GTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAP---PG-----VET 193
Query: 543 NLIDF-MGEKPPLINPNAYXXXXXXXXXXXXXXXXXXXXXXXXXISNAPYPYP-QKKPLN 716
+LID + P +N P+ YP K P +
Sbjct: 194 DLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPSANTPFSYPLPKGPSD 253
Query: 717 DNEAPM---------------SLPPKYEEFD----------------GSSSQESA--PPL 797
N PM + PP YE D G + SA P
Sbjct: 254 FNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQIVGPGPKPEASAKLPSR 313
Query: 798 PPNGPNDLFLPEIPS 842
P + ++ LPE+PS
Sbjct: 314 PADNYDNFVLPELPS 328
>sp|P53843|YN05_YEAST Hypothetical 34.5 kDa protein in PIK1-POL2 intergenic region
Length = 298
Score = 91.7 bits (226), Expect = 3e-18
Identities = 64/204 (31%), Positives = 111/204 (54%), Gaps = 8/204 (3%)
Frame = +3
Query: 3 LKLLEKKNTEIALKSRKEIADYLTSAKYDRARIKVEMIIRQDYLVEVYELIEMFCDLLLA 182
L+ ++K IA +SR+++A L + K +A +VE +I D +E+ E++E++C+LLLA
Sbjct: 23 LRYAQEKQQAIAKQSRRQVAQLLLTNKEQKAHYRVETLIHDDIHIELLEILELYCELLLA 82
Query: 183 RFGLIE--------CQKEIDPGLEEQIATLIWVTPRLQTDVQELKLITDQLHLKYGREYG 338
R +I ++ +D G+ E I +LI+ +V+EL + D + K E+
Sbjct: 83 RVQVINDISTEEQLVKEHMDDGINEAIRSLIYAI-LFVDEVKELSQLKDLMAWKINVEFV 141
Query: 339 LACQSNSLNNVNEKVMEKLSIKAPPKRLVEQYLVEIAKSFDVPYEPEEDIDPPASNWNPG 518
++ + +V EK+++K S P + LV+ YL EIAK++DVPY E+ +S+
Sbjct: 142 NGVIADHI-DVPEKIIKKCSPSVPKEELVDLYLKEIAKTYDVPYSKLENSLSSSSSNISS 200
Query: 519 EFYAPLPPNLIDFMGEKPPLINPN 590
+F P ++ D EKP L N
Sbjct: 201 DFSDP-SGDIEDNDEEKPILALDN 223
>sp|Q9ULJ6|ZIM10_HUMAN Retinoic acid-induced protein 17 (PIAS-like protein Zimp10)
Length = 1067
Score = 36.2 bits (82), Expect = 0.15
Identities = 33/142 (23%), Positives = 51/142 (35%), Gaps = 19/142 (13%)
Frame = +3
Query: 513 PGEFYAPLPPNLI---DFMGEK-----------PPLINPNAYXXXXXXXXXXXXXXXXXX 650
PG++ AP PP + ++ G++ PP +N Y
Sbjct: 428 PGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSY 487
Query: 651 XXXXXXXISNAPYPYP----QKKPLNDNEAPMSLPPKYEEFDGSSSQESAPPLPPN-GPN 815
++ P P P P+ N P P S SQ+ PP PP+ PN
Sbjct: 488 SNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPN 547
Query: 816 DLFLPEIPSDQNNTIHRLVPVQ 881
LP P++ N+ + PV+
Sbjct: 548 MSALPPPPANHNDELRLTFPVR 569
>sp|Q12446|LAS17_YEAST Proline-rich protein LAS17
Length = 633
Score = 34.7 bits (78), Expect = 0.42
Identities = 20/57 (35%), Positives = 29/57 (50%)
Frame = +3
Query: 687 YPYPQKKPLNDNEAPMSLPPKYEEFDGSSSQESAPPLPPNGPNDLFLPEIPSDQNNT 857
+P PL + AP+ PP++ S Q +AP P + P +PEIPS Q+ T
Sbjct: 234 HPKHSLPPLPNQFAPLPDPPQHN----SPPQNNAPSQPQSNPFPFPIPEIPSTQSAT 286
>sp|O43313|Y0431_HUMAN Hypothetical protein KIAA0431
Length = 667
Score = 34.3 bits (77), Expect = 0.55
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = +3
Query: 672 ISNAPYPYPQKKPLNDNEAPMSLPPKYEEFDGSSSQESAPPLPPNGPNDLFLPE 833
++N P P P + L +E + L P +E+ GS++ + PP P L LP+
Sbjct: 91 LNNQPIPRPDTQELEASE--IKLEPSFEDSCGSNTDKQTLTTPPRYPQKLLLPK 142
>sp|Q6UB99|ANR11_HUMAN Ankyrin repeat domain protein 11 (Ankyrin repeat-containing cofactor
1)
Length = 2664
Score = 32.7 bits (73), Expect = 1.6
Identities = 28/73 (38%), Positives = 33/73 (45%), Gaps = 16/73 (21%)
Frame = +3
Query: 675 SNAPYPYPQKKPLNDNEAPMSLP---PKYEEF-DGS-------SSQESAPPLPPNGPNDL 821
S APYP P P AP +LP P E+ DG S+ E+AP PP+G
Sbjct: 2012 SEAPYPAPPASP-----APYALPVAEPGLEDVKDGVDAVPAAISTSEAAPYAPPSGLESF 2066
Query: 822 F-----LPEIPSD 845
F LPE P D
Sbjct: 2067 FSNCKSLPEAPLD 2079
>sp|Q8CI61|BAG4_MOUSE BAG-family molecular chaperone regulator-4 (BCL2-associated
athanogene 4) (BAG-4) (Silencer of death domains)
Length = 457
Score = 31.2 bits (69), Expect = 4.7
Identities = 17/61 (27%), Positives = 25/61 (40%)
Frame = +3
Query: 681 APYPYPQKKPLNDNEAPMSLPPKYEEFDGSSSQESAPPLPPNGPNDLFLPEIPSDQNNTI 860
A YP+P P + + + + G+SS + P PP P D PS Q +
Sbjct: 252 ARYPWPSAAPSAPSAGSLYMTESASPWPGNSSPQPPPSPPPQQPKDPSYSYNPSGQGLSR 311
Query: 861 H 863
H
Sbjct: 312 H 312
>sp|O95466|FMNL_HUMAN Formin-like 1 protein (Formin-like protein) (Leukocyte formin)
(CLL-associated antigen KW-13)
Length = 1100
Score = 31.2 bits (69), Expect = 4.7
Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 1/45 (2%)
Frame = +3
Query: 681 APYPYPQKKPL-NDNEAPMSLPPKYEEFDGSSSQESAPPLPPNGP 812
AP P P L + EAP S PP+ GS APPLP + P
Sbjct: 541 APPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLP 585
>sp|Q6P1E1|ZIM10_MOUSE Retinoic acid-induced protein 17 (PIAS-like protein Zimp10)
Length = 1072
Score = 31.2 bits (69), Expect = 4.7
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Frame = +3
Query: 681 APYPYPQKKPLNDNEAPMSLPPKYEEFDGSSSQESAPPLPPN-GPNDLFLPEIPSDQNNT 857
A YP+ P+ N P P S SQ+ PP PP+ PN LP P++ N+
Sbjct: 512 ANYPH---SPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPANHNDE 568
Query: 858 IHRLVPVQ 881
+ PV+
Sbjct: 569 LRLTFPVR 576
>sp|Q8CHI5|PER1_RAT Period circadian protein 1 (rPER1)
Length = 1244
Score = 31.2 bits (69), Expect = 4.7
Identities = 15/48 (31%), Positives = 22/48 (45%)
Frame = +3
Query: 672 ISNAPYPYPQKKPLNDNEAPMSLPPKYEEFDGSSSQESAPPLPPNGPN 815
+ N +P P P ++AP+ PP S S PP PP+ P+
Sbjct: 919 LPNYLFPSPTSYPYGVSQAPVEGPPTPASHSPSPSLPPPPPSPPHRPD 966
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 109,518,124
Number of Sequences: 369166
Number of extensions: 2303206
Number of successful extensions: 6975
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6252
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6910
length of database: 68,354,980
effective HSP length: 111
effective length of database: 47,849,395
effective search space used: 10287619925
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)