Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_D24
(704 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O95861|BPNT1_HUMAN 3'(2'),5'-bisphosphate nucleotidase 1... 132 7e-31
sp|Q9Z1N4|BPNT1_RAT 3'(2'),5'-bisphosphate nucleotidase 1 (... 132 1e-30
sp|Q9Z0S1|BPNT1_MOUSE 3'(2'),5'-bisphosphate nucleotidase 1... 131 2e-30
sp|P49441|INPP_HUMAN Inositol polyphosphate 1-phosphatase (... 50 8e-06
sp|P49442|INPP_MOUSE Inositol polyphosphate 1-phosphatase (... 47 4e-05
sp|P21327|INPP_BOVIN Inositol polyphosphate 1-phosphatase (... 47 6e-05
sp|P70714|CYSQ_ACTAC Protein cysQ homolog 41 0.003
sp|Q19420|IMPA1_CAEEL Probable inositol monophosphatase (IM... 39 0.010
sp|Q9CNV8|SUHB_PASMU Inositol-1-monophosphatase (IMPase) (I... 38 0.023
sp|Q9PAM0|SUHB_XYLFA Inositol-1-monophosphatase (IMPase) (I... 36 0.11
>sp|O95861|BPNT1_HUMAN 3'(2'),5'-bisphosphate nucleotidase 1 (Bisphosphate 3'-nucleotidase
1) (PAP-inositol-1,4-phosphatase) (PIP)
Length = 308
Score = 132 bits (333), Expect = 7e-31
Identities = 68/172 (39%), Positives = 101/172 (58%), Gaps = 4/172 (2%)
Frame = +3
Query: 3 RPIGGVIHQPF----SPSDNNKGRSIFALEGMGCFGFERRFSXXXXXXXXXXXILTTTRG 170
+ I GVI+QP+ + D GR+I+ + G+G FGF+ + I+TTTR
Sbjct: 144 KAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLK------EVPAGKHIITTTRS 197
Query: 171 HGTPTVNQALESCGPTEIVRVGGCGHKIILLLEGRCHGYIFASAGCKKWDTCAPEAVLRE 350
H V + + P ++RVGG G+KII L+EG+ Y+FAS GCKKWDTCAPE +L
Sbjct: 198 HSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHA 257
Query: 351 AGGYLTDMLGRRITYERDVDKSNRFGVLATAKKDWHQTYLNKIPQFVKDHII 506
GG LTD+ G + Y +DV N GVLAT + + Y +++P+ +K+ ++
Sbjct: 258 VGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRN--YDYYASRVPESIKNALV 307
>sp|Q9Z1N4|BPNT1_RAT 3'(2'),5'-bisphosphate nucleotidase 1 (Bisphosphate 3'-nucleotidase
1) (PAP-inositol-1,4-phosphatase) (PIP) (scHAL2
analogous 3)
Length = 308
Score = 132 bits (331), Expect = 1e-30
Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 4/172 (2%)
Frame = +3
Query: 3 RPIGGVIHQPF----SPSDNNKGRSIFALEGMGCFGFERRFSXXXXXXXXXXXILTTTRG 170
+ I G+I+QP+ + D GR+I+ + G+G FGF+ + + I+TTTR
Sbjct: 144 KAIAGIINQPYYNYQAGPDAVLGRTIWGVLGLGAFGFQLKEAPAGKH------IITTTRS 197
Query: 171 HGTPTVNQALESCGPTEIVRVGGCGHKIILLLEGRCHGYIFASAGCKKWDTCAPEAVLRE 350
H V + + P ++RVGG G+KII L+EG+ Y+FAS GCKKWDTCAPE +L
Sbjct: 198 HSNKLVTDCIAAMNPDNVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHA 257
Query: 351 AGGYLTDMLGRRITYERDVDKSNRFGVLATAKKDWHQTYLNKIPQFVKDHII 506
GG LTD+ G + Y+++V N GVLA + ++ Y +++P+ VK +I
Sbjct: 258 VGGKLTDIHGNPLQYDKEVKHMNSAGVLAALRN--YEYYASRVPESVKSALI 307
>sp|Q9Z0S1|BPNT1_MOUSE 3'(2'),5'-bisphosphate nucleotidase 1 (Bisphosphate 3'-nucleotidase
1) (PAP-inositol-1,4-phosphatase) (PIP)
Length = 308
Score = 131 bits (329), Expect = 2e-30
Identities = 67/172 (38%), Positives = 101/172 (58%), Gaps = 4/172 (2%)
Frame = +3
Query: 3 RPIGGVIHQPF----SPSDNNKGRSIFALEGMGCFGFERRFSXXXXXXXXXXXILTTTRG 170
+ I G+I+QP+ + D GR+I+ + G+G FGF+ + + I+TTTR
Sbjct: 144 KAIAGIINQPYYNYQAGPDAALGRTIWGVLGLGAFGFQLKEAPAGKH------IITTTRS 197
Query: 171 HGTPTVNQALESCGPTEIVRVGGCGHKIILLLEGRCHGYIFASAGCKKWDTCAPEAVLRE 350
H V + + P ++RVGG G+KII L+EG+ Y+FAS GCKKWDTCAPE +L
Sbjct: 198 HSNQLVTDCISAMNPDTVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHA 257
Query: 351 AGGYLTDMLGRRITYERDVDKSNRFGVLATAKKDWHQTYLNKIPQFVKDHII 506
GG LTD+ G + Y ++V N GVLA + ++ Y + +P+ VK+ +I
Sbjct: 258 VGGKLTDIHGNALQYNKEVKHMNSAGVLAALRN--YEYYASHVPESVKNALI 307
>sp|P49441|INPP_HUMAN Inositol polyphosphate 1-phosphatase (IPPase) (IPP)
Length = 399
Score = 49.7 bits (117), Expect = 8e-06
Identities = 38/139 (27%), Positives = 57/139 (41%), Gaps = 16/139 (11%)
Frame = +3
Query: 6 PIGGVIHQPFSPSDNN----KGRSIFALEGMGCFGFERRFSXXXXXXXXXXXILTTTRGH 173
P+ GVI+QPF D N KG+ + L MG + + T +
Sbjct: 196 PLMGVINQPFVSRDPNTLRWKGQCYWGLSYMGTNMHSLQLTISRRNGSETHTGNTGSEAA 255
Query: 174 GTP------------TVNQALESCGPTEIVRVGGCGHKIILLLEGRCHGYIFASAGCKKW 317
+P T+ AL I G G+K + +++G YIF+ KW
Sbjct: 256 FSPSFSAVISTSEKETIKAALSRVCGDRIFGAAGAGYKSLCVVQGLVDIYIFSEDTTFKW 315
Query: 318 DTCAPEAVLREAGGYLTDM 374
D+CA A+LR GG + D+
Sbjct: 316 DSCAAHAILRAMGGGIVDL 334
>sp|P49442|INPP_MOUSE Inositol polyphosphate 1-phosphatase (IPPase) (IPP)
Length = 396
Score = 47.4 bits (111), Expect = 4e-05
Identities = 38/145 (26%), Positives = 60/145 (41%), Gaps = 22/145 (15%)
Frame = +3
Query: 6 PIGGVIHQPFSPSDNN----KGRSIFALEGMGCF------------------GFERRFSX 119
P+ GVI+QPF+ + KG+ + L MG +R FS
Sbjct: 196 PLMGVINQPFASQNLTTLRWKGQCYWGLSYMGTNIHSLQLAISKSDSETQTENSDREFSS 255
Query: 120 XXXXXXXXXXILTTTRGHGTPTVNQALESCGPTEIVRVGGCGHKIILLLEGRCHGYIFAS 299
+++T+ T+ AL + G G+K + +++G YIF+
Sbjct: 256 PFSA------VISTSE---KDTIKAALSRVCGGSVFPAAGAGYKSLCVIQGLADIYIFSE 306
Query: 300 AGCKKWDTCAPEAVLREAGGYLTDM 374
KWD+CA A+LR GG + DM
Sbjct: 307 DTTYKWDSCAAHAILRAMGGGIVDM 331
>sp|P21327|INPP_BOVIN Inositol polyphosphate 1-phosphatase (IPPase) (IPP)
Length = 400
Score = 46.6 bits (109), Expect = 6e-05
Identities = 23/64 (35%), Positives = 33/64 (51%)
Frame = +3
Query: 183 TVNQALESCGPTEIVRVGGCGHKIILLLEGRCHGYIFASAGCKKWDTCAPEAVLREAGGY 362
T+ AL I R G G+K + ++ G YIF+ KWD+CA A+LR GG
Sbjct: 272 TIKGALSHVCGERIFRAAGAGYKSLCVILGLADIYIFSEDTTFKWDSCAAHAILRAMGGG 331
Query: 363 LTDM 374
+ D+
Sbjct: 332 MVDL 335
>sp|P70714|CYSQ_ACTAC Protein cysQ homolog
Length = 269
Score = 41.2 bits (95), Expect = 0.003
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 5/138 (3%)
Frame = +3
Query: 3 RPIGGVIHQPFSPSDNNKGRSIFALEGMGCF----GFERRFSXXXXXXXXXXXILTTTRG 170
+P+ GVIH P G + +A++G G + G + + I +
Sbjct: 115 QPVLGVIHAPML------GSTYYAMQGFGAYKHHDGQHLKLAFHDIQADNALRIAVGSAA 168
Query: 171 HGTPTVNQALESCGPTEIVRVGGCGHKIILLLEGRCHGYIFASAGCK-KWDTCAPEAVLR 347
V L E G G K L+ +G C YI GC +WDT A E +L
Sbjct: 169 -AAEKVRSILNKNLAYEFHICGSSGLKSTLVADGVCDCYI--RLGCTGEWDTAASEILLA 225
Query: 348 EAGGYLTDMLGRRITYER 401
E GG + D+ + +TY +
Sbjct: 226 EMGGIIFDLNYQPLTYNK 243
>sp|Q19420|IMPA1_CAEEL Probable inositol monophosphatase (IMPase) (IMP) (Inositol-1(or
4)-monophosphatase)
Length = 341
Score = 39.3 bits (90), Expect = 0.010
Identities = 16/43 (37%), Positives = 25/43 (58%)
Frame = +3
Query: 252 IILLLEGRCHGYIFASAGCKKWDTCAPEAVLREAGGYLTDMLG 380
++++ +G C GY+ G WD AP ++ EAGG +TD G
Sbjct: 266 MVMVAQGSCDGYV--EYGIHAWDVAAPSIIVTEAGGVVTDPTG 306
>sp|Q9CNV8|SUHB_PASMU Inositol-1-monophosphatase (IMPase) (Inositol-1-phosphatase)
(I-1-Pase)
Length = 267
Score = 38.1 bits (87), Expect = 0.023
Identities = 20/65 (30%), Positives = 31/65 (47%)
Frame = +3
Query: 186 VNQALESCGPTEIVRVGGCGHKIILLLEGRCHGYIFASAGCKKWDTCAPEAVLREAGGYL 365
+N ++ C + R+G + + GR GY G K WD A + ++REAGG +
Sbjct: 172 MNNLIQDCA--DFRRMGSAALDLCYVAAGRVDGYF--EVGVKAWDIAAGDLIVREAGGLV 227
Query: 366 TDMLG 380
D G
Sbjct: 228 CDFNG 232
>sp|Q9PAM0|SUHB_XYLFA Inositol-1-monophosphatase (IMPase) (Inositol-1-phosphatase)
(I-1-Pase)
Length = 275
Score = 35.8 bits (81), Expect = 0.11
Identities = 20/54 (37%), Positives = 26/54 (48%)
Frame = +3
Query: 219 EIVRVGGCGHKIILLLEGRCHGYIFASAGCKKWDTCAPEAVLREAGGYLTDMLG 380
+I R G + + GR Y AG K WD A ++REAGGY+ D G
Sbjct: 180 DIRRSGSAALDLAYVACGRADAYF--EAGIKVWDVAAGMLLVREAGGYVCDFKG 231
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,182,976
Number of Sequences: 369166
Number of extensions: 1628071
Number of successful extensions: 3504
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3402
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3500
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6170718545
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)