Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_D07
(644 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q01105|SET_HUMAN SET protein (Phosphatase 2A inhibitor I... 125 1e-28
sp|Q9EQU5|SET_MOUSE SET protein (Phosphatase 2A inhibitor I... 125 1e-28
sp|Q63945|SET_RAT SET protein (Phosphatase 2A inhibitor I2P... 125 1e-28
sp|P53997|SET_DROME SET protein 120 2e-27
sp|Q18240|SPR2_CAEEL Suppressor of presenilin 2 117 2e-26
sp|O88852|TSYL1_MOUSE Testis-specific Y-encoded-like protei... 91 3e-18
sp|Q9H0U9|TSYL1_HUMAN Testis-specific Y-encoded-like protei... 89 7e-18
sp|Q9UJ04|TSYL4_HUMAN Testis-specific Y-encoded-like protei... 87 3e-17
sp|Q9H489|TSY3_HUMAN Testis-specific Y-encoded-like protein... 84 3e-16
sp|Q01534|TSPY1_HUMAN Testis-specific Y-encoded protein 1 84 3e-16
>sp|Q01105|SET_HUMAN SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I) (HLA-DR
associated protein II) (PHAPII) (Inhibitor of granzyme
A-activated DNase) (IGAAD)
Length = 290
Score = 125 bits (313), Expect = 1e-28
Identities = 62/144 (43%), Positives = 82/144 (56%), Gaps = 1/144 (0%)
Frame = +1
Query: 1 NFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTI 180
NFW+ NHPQ+ L+ E DE+ L LT ++V EF+DIKSG++I F N YF N +
Sbjct: 93 NFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVL 152
Query: 181 TKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDI 357
+K H+ ES + + + WK GK+ K +++ N P SF WFT
Sbjct: 153 SKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQN--KASRKRQHEEPESFFTWFTDHS 210
Query: 358 ANSMVELGEVIKDDLWPNPLQYYL 429
ELGEVIKDD+WPNPLQYYL
Sbjct: 211 DAGADELGEVIKDDIWPNPLQYYL 234
>sp|Q9EQU5|SET_MOUSE SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I)
Length = 289
Score = 125 bits (313), Expect = 1e-28
Identities = 62/144 (43%), Positives = 82/144 (56%), Gaps = 1/144 (0%)
Frame = +1
Query: 1 NFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTI 180
NFW+ NHPQ+ L+ E DE+ L LT ++V EF+DIKSG++I F N YF N +
Sbjct: 92 NFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVL 151
Query: 181 TKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDI 357
+K H+ ES + + + WK GK+ K +++ N P SF WFT
Sbjct: 152 SKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQN--KASRKRQHEEPESFFTWFTDHS 209
Query: 358 ANSMVELGEVIKDDLWPNPLQYYL 429
ELGEVIKDD+WPNPLQYYL
Sbjct: 210 DAGADELGEVIKDDIWPNPLQYYL 233
>sp|Q63945|SET_RAT SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A)
(Template-activating factor I) (TAF-I) (Liver
regeneration-related protein LRRGR00002)
Length = 289
Score = 125 bits (313), Expect = 1e-28
Identities = 62/144 (43%), Positives = 82/144 (56%), Gaps = 1/144 (0%)
Frame = +1
Query: 1 NFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTI 180
NFW+ NHPQ+ L+ E DE+ L LT ++V EF+DIKSG++I F N YF N +
Sbjct: 92 NFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVL 151
Query: 181 TKSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDI 357
+K H+ ES + + + WK GK+ K +++ N P SF WFT
Sbjct: 152 SKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQN--KASRKRQHEEPESFFTWFTDHS 209
Query: 358 ANSMVELGEVIKDDLWPNPLQYYL 429
ELGEVIKDD+WPNPLQYYL
Sbjct: 210 DAGADELGEVIKDDIWPNPLQYYL 233
>sp|P53997|SET_DROME SET protein
Length = 269
Score = 120 bits (302), Expect = 2e-27
Identities = 60/150 (40%), Positives = 83/150 (55%), Gaps = 7/150 (4%)
Frame = +1
Query: 1 NFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTI 180
NFW+ + NHPQ+ ++ E +E+ L +L L+VEEF+DIKSG++I F N YF N +
Sbjct: 81 NFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIKSGYRINFHFDENPYFENKVL 140
Query: 181 TKSIHVGESEIK-------TTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQ 339
TK H+ + +T P+ WKEGKN +K L L +F
Sbjct: 141 TKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLKLL---LTKPYGNKKKRNSEYKTFFD 197
Query: 340 WFTSDIANSMVELGEVIKDDLWPNPLQYYL 429
WF+ + E+ E+IKDDLWPNPLQYYL
Sbjct: 198 WFSDNTDPVNDEIAELIKDDLWPNPLQYYL 227
>sp|Q18240|SPR2_CAEEL Suppressor of presenilin 2
Length = 312
Score = 117 bits (294), Expect = 2e-26
Identities = 62/143 (43%), Positives = 77/143 (53%)
Frame = +1
Query: 1 NFWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTI 180
NFW A NH L T I E EDLL +L L+V+EF+D++SGFKIIMTF PNEYF N I
Sbjct: 79 NFWQTAFLNHHLLSTAIPEEQEDLLAALRDLEVQEFEDLRSGFKIIMTFDPNEYFTNEVI 138
Query: 181 TKSIHVGESEIKTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIA 360
TKS H+ T ++WKE K +F++W T
Sbjct: 139 TKSYHLQSESPSTEITEIEWKENKK-------------PPFPEDGDSAHTFLEWLTYAAL 185
Query: 361 NSMVELGEVIKDDLWPNPLQYYL 429
E+ EVIKDDL+ NPLQYY+
Sbjct: 186 PDSDEIAEVIKDDLYVNPLQYYV 208
>sp|O88852|TSYL1_MOUSE Testis-specific Y-encoded-like protein 1 (TSPY-like 1)
Length = 379
Score = 90.9 bits (224), Expect = 3e-18
Identities = 50/146 (34%), Positives = 73/146 (50%), Gaps = 4/146 (2%)
Frame = +1
Query: 4 FWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTIT 183
FW+ A NHPQL +I D ++L+ +TSL+V+E K+G K F N YF N I
Sbjct: 220 FWMTAFRNHPQLSAMIRGRDAEMLRYVTSLEVKELRHPKTGCKFKFFFRRNPYFRNKLIV 279
Query: 184 KSIHVGES-EIKTTCDPVDWKEG---KNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTS 351
K V S + + P+ W+ G ++F++ + + SF WF+
Sbjct: 280 KEYEVRSSGRVVSLSTPIIWRRGHEPQSFIRRNQDLI--------------CSFFTWFSD 325
Query: 352 DIANSMVELGEVIKDDLWPNPLQYYL 429
+ E+IK+DLWPNPLQYYL
Sbjct: 326 HSLPESDRIAEIIKEDLWPNPLQYYL 351
>sp|Q9H0U9|TSYL1_HUMAN Testis-specific Y-encoded-like protein 1 (TSPY-like 1)
Length = 438
Score = 89.4 bits (220), Expect = 7e-18
Identities = 48/146 (32%), Positives = 74/146 (50%), Gaps = 4/146 (2%)
Frame = +1
Query: 4 FWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTIT 183
FW+ A NHPQL +I D ++L+ +T+L+V+E ++G K F N YF N I
Sbjct: 279 FWMTAFRNHPQLSAMIRGQDAEMLRYITNLEVKELRHPRTGCKFKFFFRRNPYFRNKLIV 338
Query: 184 KSIHVGES-EIKTTCDPVDWKEG---KNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTS 351
K V S + + P+ W+ G ++F++ + + SF WF+
Sbjct: 339 KEYEVRSSGRVVSLSTPIIWRRGHEPQSFIRRNQDLI--------------CSFFTWFSD 384
Query: 352 DIANSMVELGEVIKDDLWPNPLQYYL 429
++ E+IK+DLWPNPLQYYL
Sbjct: 385 HSLPESDKIAEIIKEDLWPNPLQYYL 410
>sp|Q9UJ04|TSYL4_HUMAN Testis-specific Y-encoded-like protein 4 (TSPY-like 4)
Length = 414
Score = 87.4 bits (215), Expect = 3e-17
Identities = 46/143 (32%), Positives = 69/143 (48%), Gaps = 1/143 (0%)
Frame = +1
Query: 4 FWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTIT 183
FW+ A NHPQL +I+ DED+L+ + +L+VEE ++G K F N YF N +
Sbjct: 253 FWVTAFRNHPQLSPMISGQDEDMLRYMINLEVEELKHPRAGCKFKFIFQGNPYFRNEGLV 312
Query: 184 KSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIA 360
K S + + P+ W G++ ++ + SF WF+
Sbjct: 313 KEYERRSSGRVVSLSTPIRWHRGQDPQAHIHRNREGNTIP---------SFFNWFSDHSL 363
Query: 361 NSMVELGEVIKDDLWPNPLQYYL 429
+ E+IK +LWPNPLQYYL
Sbjct: 364 LEFDRIAEIIKGELWPNPLQYYL 386
>sp|Q9H489|TSY3_HUMAN Testis-specific Y-encoded-like protein 3 (TSPY-like 3)
Length = 355
Score = 84.0 bits (206), Expect = 3e-16
Identities = 47/143 (32%), Positives = 67/143 (46%), Gaps = 1/143 (0%)
Frame = +1
Query: 4 FWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTIT 183
FW+ A NHPQL +I+ DED+L L +L+V E ++G K F N YF N I
Sbjct: 195 FWVTAFLNHPQLSAMISPRDEDMLCYLMNLEVRELRHSRTGCKFKFRFWSNPYFQNKVIV 254
Query: 184 KSIHVGES-EIKTTCDPVDWKEGKNFVKSLNESLNXXXXXXXXXXXXPISFMQWFTSDIA 360
K S + + + W G+ ++ + + SF WF+
Sbjct: 255 KEYECRASGRVVSIATRIRWHWGQEPPALVHRNRDTVR-----------SFFSWFSQHSL 303
Query: 361 NSMVELGEVIKDDLWPNPLQYYL 429
+ ++IKDDLWPNPLQYYL
Sbjct: 304 PEADRVAQIIKDDLWPNPLQYYL 326
>sp|Q01534|TSPY1_HUMAN Testis-specific Y-encoded protein 1
Length = 308
Score = 84.0 bits (206), Expect = 3e-16
Identities = 50/146 (34%), Positives = 70/146 (47%), Gaps = 5/146 (3%)
Frame = +1
Query: 4 FWINALSNHPQLMTLITEHDEDLLQSLTSLDVEEFDDIKSGFKIIMTFSPNEYFNNTTIT 183
FW N ++NHPQ+ LIT+ DED+L + SL+VEE KI++ F N YF N IT
Sbjct: 158 FWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHLCKIMLFFRSNPYFQNKVIT 217
Query: 184 KSIHVGESEIKTT-CDPVDWKEGKNFV----KSLNESLNXXXXXXXXXXXXPISFMQWFT 348
K V +E + + P++W + N SLN F WF+
Sbjct: 218 KEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLN---------------FFNWFS 262
Query: 349 SDIANSMVELGEVIKDDLWPNPLQYY 426
++ E++ DLW NPLQYY
Sbjct: 263 DHNFAGSNKIAEILCKDLWRNPLQYY 288
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,746,919
Number of Sequences: 369166
Number of extensions: 1036238
Number of successful extensions: 2654
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2586
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2624
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5267491560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)