Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_D03
(857 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9D964|GATM_MOUSE Glycine amidinotransferase, mitochondr... 293 4e-79
sp|P50441|GATM_PIG Glycine amidinotransferase (L-arginine:g... 292 9e-79
sp|P50442|GATM_RAT Glycine amidinotransferase, mitochondria... 291 2e-78
sp|P50440|GATM_HUMAN Glycine amidinotransferase, mitochondr... 289 6e-78
sp|Q54258|STRB1_STRGA Inosamine-phosphate amidinotransferas... 121 3e-27
sp|P08078|STRB1_STRGR Inosamine-phosphate amidinotransferas... 112 2e-24
sp|P29780|STRB2_STRGR Putative inosamine-phosphate amidinot... 99 1e-20
sp|Q54264|STRB2_STRGA Putative inosamine-phosphate amidinot... 83 1e-15
sp|O53237|LEU2_MYCTU 3-isopropylmalate dehydratase large su... 33 1.3
sp|Q7TXH6|LEU2_MYCBO 3-isopropylmalate dehydratase large su... 33 1.3
>sp|Q9D964|GATM_MOUSE Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 293 bits (750), Expect = 4e-79
Identities = 141/245 (57%), Positives = 178/245 (72%), Gaps = 2/245 (0%)
Frame = +1
Query: 1 IESTMTWRSRYFEFMCYKTLIKDYWRRGAKWTAAPKPMCRESLFKENYCAD--EDSTAFF 174
IE+ M WRSR+FE+ Y+++IKDY+ RGAKWT APKP + L+ +NY ED
Sbjct: 180 IEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQNYPIHSVEDRHKLA 239
Query: 175 DEKTSILTEEEPVFDAADFIRCGRDIFAHVSQVSNNSGIEWVRRHLAPKGIRVHALNFVD 354
+ + TE EP FDAADFIR GRDIFA SQV+N GIEW+RRHLAP RVH ++F D
Sbjct: 240 AQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPD-YRVHIISFKD 298
Query: 355 PKPMHIDTTLFTPRPGVAITCPDRPCLQIGLFKKAGWDVVVAPYPDIPKNFPYYISSQWL 534
P PMHID T PG+ ++ PDRPC QI LFKKAGW +V P P IP + P ++SS+WL
Sbjct: 299 PNPMHIDATFNIIGPGLVLSNPDRPCHQIDLFKKAGWTIVTPPTPVIPDDHPLWMSSKWL 358
Query: 535 SLNVVMLDEKRVLVEKDEVGIQKLFEKVGIKSVKVPFKHCFSIGGGIHCWTSDVRRRGDL 714
S+NV+MLDEKRV+V+ +EV IQK+FEK+GI ++KV ++ S+GGG HCWT DVRRRG L
Sbjct: 359 SMNVLMLDEKRVMVDANEVPIQKMFEKLGISTIKVNIRNANSLGGGFHCWTCDVRRRGTL 418
Query: 715 QNYFD 729
Q+YFD
Sbjct: 419 QSYFD 423
>sp|P50441|GATM_PIG Glycine amidinotransferase (L-arginine:glycine amidinotransferase)
(Transamidinase) (AT)
Length = 386
Score = 292 bits (747), Expect = 9e-79
Identities = 138/245 (56%), Positives = 180/245 (73%), Gaps = 2/245 (0%)
Frame = +1
Query: 1 IESTMTWRSRYFEFMCYKTLIKDYWRRGAKWTAAPKPMCRESLFKENY--CADEDSTAFF 174
IE+ M WR+R+FE+ Y+++IKDY+RRGAKWT APKP + L+ ++Y + ED
Sbjct: 143 IEAPMAWRARFFEYRAYRSIIKDYFRRGAKWTTAPKPTMADELYDQDYPIYSVEDRHKLA 202
Query: 175 DEKTSILTEEEPVFDAADFIRCGRDIFAHVSQVSNNSGIEWVRRHLAPKGIRVHALNFVD 354
+ + TE EP FDAADFIR GRDIFA SQV+N GIEW+R+HLAP RVH ++F D
Sbjct: 203 AQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYMGIEWMRKHLAPD-YRVHIISFKD 261
Query: 355 PKPMHIDTTLFTPRPGVAITCPDRPCLQIGLFKKAGWDVVVAPYPDIPKNFPYYISSQWL 534
P PMHID T PG+ ++ PDRPC QI LFKKAGW +V P P IP + P ++SS+WL
Sbjct: 262 PNPMHIDATFNIIGPGLVLSNPDRPCHQIDLFKKAGWTIVTPPIPVIPDDHPLWMSSKWL 321
Query: 535 SLNVVMLDEKRVLVEKDEVGIQKLFEKVGIKSVKVPFKHCFSIGGGIHCWTSDVRRRGDL 714
S+NV+MLDEKRV+V+ +EV IQK+FEK+GI ++K+ ++ S+GGG HCWT DVRRRG L
Sbjct: 322 SMNVLMLDEKRVMVDANEVPIQKMFEKLGISTIKISIRNANSLGGGFHCWTCDVRRRGTL 381
Query: 715 QNYFD 729
Q+YFD
Sbjct: 382 QSYFD 386
>sp|P50442|GATM_RAT Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 291 bits (745), Expect = 2e-78
Identities = 140/245 (57%), Positives = 178/245 (72%), Gaps = 2/245 (0%)
Frame = +1
Query: 1 IESTMTWRSRYFEFMCYKTLIKDYWRRGAKWTAAPKPMCRESLFKENYCAD--EDSTAFF 174
IE+ M WRSR+FE+ Y+++IKDY+ RGAKWT APKP + L+ ++Y ED
Sbjct: 180 IEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQDYPIHSVEDRHKLA 239
Query: 175 DEKTSILTEEEPVFDAADFIRCGRDIFAHVSQVSNNSGIEWVRRHLAPKGIRVHALNFVD 354
+ + TE EP FDAADFIR GRDIFA SQV+N GIEW+RRHLAP RVH ++F D
Sbjct: 240 AQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPD-YRVHIISFKD 298
Query: 355 PKPMHIDTTLFTPRPGVAITCPDRPCLQIGLFKKAGWDVVVAPYPDIPKNFPYYISSQWL 534
P PMHID T PG+ ++ PDRPC QI LFKKAGW +V P P IP + P ++SS+WL
Sbjct: 299 PNPMHIDATFNIIGPGLVLSNPDRPCHQIDLFKKAGWTIVTPPTPVIPDDHPLWMSSKWL 358
Query: 535 SLNVVMLDEKRVLVEKDEVGIQKLFEKVGIKSVKVPFKHCFSIGGGIHCWTSDVRRRGDL 714
S+NV+MLDEKRV+V+ +EV IQK+FEK+GI ++KV ++ S+GGG HCWT DVRRRG L
Sbjct: 359 SMNVLMLDEKRVMVDANEVPIQKMFEKLGISTIKVNIRNANSLGGGFHCWTCDVRRRGTL 418
Query: 715 QNYFD 729
Q+YFD
Sbjct: 419 QSYFD 423
>sp|P50440|GATM_HUMAN Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 289 bits (740), Expect = 6e-78
Identities = 138/245 (56%), Positives = 177/245 (72%), Gaps = 2/245 (0%)
Frame = +1
Query: 1 IESTMTWRSRYFEFMCYKTLIKDYWRRGAKWTAAPKPMCRESLFKENYCAD--EDSTAFF 174
IE+ M WRSR+FE+ Y+++IKDY+ RGAKWT APKP + L+ ++Y ED
Sbjct: 180 IEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLA 239
Query: 175 DEKTSILTEEEPVFDAADFIRCGRDIFAHVSQVSNNSGIEWVRRHLAPKGIRVHALNFVD 354
+ + TE EP FDAADFIR GRDIFA SQV+N GIEW+RRHLAP RVH ++F D
Sbjct: 240 AQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPD-YRVHIISFKD 298
Query: 355 PKPMHIDTTLFTPRPGVAITCPDRPCLQIGLFKKAGWDVVVAPYPDIPKNFPYYISSQWL 534
P PMHID T PG+ ++ PDRPC QI LFKKAGW ++ P P IP + P ++SS+WL
Sbjct: 299 PNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWL 358
Query: 535 SLNVVMLDEKRVLVEKDEVGIQKLFEKVGIKSVKVPFKHCFSIGGGIHCWTSDVRRRGDL 714
S+NV+MLDEKRV+V+ +EV IQK+FEK+GI ++KV ++ S+GGG HCWT DVRRRG L
Sbjct: 359 SMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTL 418
Query: 715 QNYFD 729
Q+Y D
Sbjct: 419 QSYLD 423
>sp|Q54258|STRB1_STRGA Inosamine-phosphate amidinotransferase I (Aminocyclitol
amidinotransferase) (ADT)
Length = 348
Score = 121 bits (303), Expect = 3e-27
Identities = 75/242 (30%), Positives = 121/242 (50%), Gaps = 1/242 (0%)
Frame = +1
Query: 1 IESTMTWRSRYFEFMCYKTLIKDYWRRGAKWTAAPKPMCRESLFKENYCADEDSTAFFDE 180
IES M R+R+ E + YK ++ +Y+ GA+W +APKP + +++ A +
Sbjct: 118 IESPMALRARFLESLAYKDILLEYFASGARWLSAPKPRLADEMYEPTAPAGQR------- 170
Query: 181 KTSILTEEEPVFDAADFIRCGRDIFAHVSQVSNNSGIEWVRRHLAPKGIRVHALNFVDPK 360
LT+ EPVFDAA+ +R G D+ VS N G +W++ L +VH +
Sbjct: 171 ----LTDLEPVFDAANVLRFGTDLLYLVSDSGNELGAKWLQSALGST-YKVHPCRGLYAS 225
Query: 361 PMHIDTTLFTPRPGVAITCPDRPCLQIGLFKKAGWDVVVAP-YPDIPKNFPYYISSQWLS 537
H+D+T+ RPG+ + P R W VV P DI S W+
Sbjct: 226 T-HVDSTIVPLRPGLVLVNPARVNDDNMPDFLRSWQTVVCPELVDIGFTGDKPHCSVWIG 284
Query: 538 LNVVMLDEKRVLVEKDEVGIQKLFEKVGIKSVKVPFKHCFSIGGGIHCWTSDVRRRGDLQ 717
+N++++ +V++ + G+ K+ EK G+ + + H ++GGG HC T DVRR G L+
Sbjct: 285 MNLLVVRPDLAVVDRRQTGLIKVLEKHGVDVLPLQLTHSRTLGGGFHCATLDVRRTGSLE 344
Query: 718 NY 723
Y
Sbjct: 345 TY 346
>sp|P08078|STRB1_STRGR Inosamine-phosphate amidinotransferase I (Aminocyclitol
amidinotransferase) (ADT)
Length = 347
Score = 112 bits (279), Expect = 2e-24
Identities = 71/235 (30%), Positives = 116/235 (49%), Gaps = 1/235 (0%)
Frame = +1
Query: 1 IESTMTWRSRYFEFMCYKTLIKDYWRRGAKWTAAPKPMCRESLFKENYCADEDSTAFFDE 180
IE+ M RSR+ E + YK L+ +Y+ G++W +APKP + + A E
Sbjct: 118 IETPMALRSRFLESLAYKDLLLEYFASGSRWLSAPKPRLTDDSYAPQAPAGER------- 170
Query: 181 KTSILTEEEPVFDAADFIRCGRDIFAHVSQVSNNSGIEWVRRHLAPKGIRVHALNFVDPK 360
LT+EEPVFDAA+ +R G D+ VS N G +W++ + VH +
Sbjct: 171 ----LTDEEPVFDAANVLRFGTDLLYLVSDSGNELGAKWLQSAVGDT-YTVHPCRKLYAS 225
Query: 361 PMHIDTTLFTPRPGVAITCPDRPCLQIGLFKKAGWDVVVAP-YPDIPKNFPYYISSQWLS 537
H+D+T+ RPG+ +T P R + W+ + P DI S W+
Sbjct: 226 T-HVDSTIVPLRPGLVLTNPSRVNDENMPDFLRSWENITCPELVDIGFTGDKPHCSVWIG 284
Query: 538 LNVVMLDEKRVLVEKDEVGIQKLFEKVGIKSVKVPFKHCFSIGGGIHCWTSDVRR 702
+N++++ +V++ + + +L EK G+ + + H ++GGG HC T DVRR
Sbjct: 285 MNLLVVRPDLAVVDRRQTALIRLLEKHGMNVLPLQLTHSRTLGGGFHCATLDVRR 339
>sp|P29780|STRB2_STRGR Putative inosamine-phosphate amidinotransferase II (Aminocyclitol
amidinotransferase) (ADT)
Length = 349
Score = 99.4 bits (246), Expect = 1e-20
Identities = 69/248 (27%), Positives = 113/248 (45%), Gaps = 7/248 (2%)
Frame = +1
Query: 1 IESTMTWRSRYFEFMCYKTLIKDYWRRGAKWTAAPKPMCRESLFKENYCADEDSTAFFDE 180
IE+ M R+R+ E + YK L+ +Y G++W +APKP E ++ + + E
Sbjct: 119 IEAPMALRARFLESLAYKELLVEYLAAGSRWISAPKPRLAEGMYSPSGPSGER------- 171
Query: 181 KTSILTEEEPVFDAADFIRCGRDIFAHVSQVSNNSGIEWVRRHLAPKGIRVHALNFVDPK 360
L + EPVFDAA+ +R G D+ VS N G W++ L VH +
Sbjct: 172 ----LRDLEPVFDAANVLRLGTDLLYLVSDSGNELGARWLQSALG-AAYTVHPCRGL-YS 225
Query: 361 PMHIDTTLFTPRPGVAITCPDRPCLQIGLFKKAGWDVVVAP-------YPDIPKNFPYYI 519
HID+TL RPG+ + P R W + P D+P
Sbjct: 226 STHIDSTLVPLRPGLVLVNPARVTDDNLPGVLRTWQRIECPALAGLGYAGDVPH------ 279
Query: 520 SSQWLSLNVVMLDEKRVLVEKDEVGIQKLFEKVGIKSVKVPFKHCFSIGGGIHCWTSDVR 699
S W+ ++++++ V+V+ + ++ E+ G+ + + H +GGG H T D+R
Sbjct: 280 CSTWIGMSLLVVRPGLVVVDSRHRELMRVLERHGVDVLPLKLTHARMLGGGFHGVTLDIR 339
Query: 700 RRGDLQNY 723
R G L+ Y
Sbjct: 340 RTGALETY 347
>sp|Q54264|STRB2_STRGA Putative inosamine-phosphate amidinotransferase II (Aminocyclitol
amidinotransferase) (ADT)
Length = 319
Score = 82.8 bits (203), Expect = 1e-15
Identities = 65/228 (28%), Positives = 107/228 (46%), Gaps = 4/228 (1%)
Frame = +1
Query: 52 KTLIKDYWRRGAKWTAAPKPMCRESLFKENYCADEDSTAFFDEKTSILTEEEPVFDAADF 231
+ L+ +Y+ G++W +AP P+ + ++ D TA E+ L E EPVFDA
Sbjct: 106 RMLLMEYFTSGSRWISAPPPVLTDVMY--------DPTAPAGER---LRELEPVFDADTV 154
Query: 232 IRCGRDIFAHVSQVSNNSGIEWVRRHLAPKGIRVHALNFVDPKPMHIDTTLFTPRPGVAI 411
+R G D+ VS N G W++ L + VH P H D + PG+ +
Sbjct: 155 LRIGTDLLYLVSDSGNALGARWLQAALGER-YTVHPCRGPHGSP-HGDFAVVPLGPGLIL 212
Query: 412 TCPDRPCLQ-IGLFKKAGWDVVVAPY---PDIPKNFPYYISSQWLSLNVVMLDEKRVLVE 579
P+R + I F + W +V P P P + SS W N++++ V+V+
Sbjct: 213 VNPERVDAEHIPPFLRT-WKRIVCPELVDPGPPDGAVH--SSGWGGSNILVVRPGLVIVD 269
Query: 580 KDEVGIQKLFEKVGIKSVKVPFKHCFSIGGGIHCWTSDVRRRGDLQNY 723
+ + + ++ E GI + + H ++G G H T DVRR G L++Y
Sbjct: 270 RRQADLMRVLENNGIDVLPLQLTHARALGSGFHRVTVDVRRTGTLESY 317
>sp|O53237|LEU2_MYCTU 3-isopropylmalate dehydratase large subunit (Isopropylmalate
isomerase) (Alpha-IPM isomerase) (IPMI)
Length = 473
Score = 32.7 bits (73), Expect = 1.3
Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +1
Query: 247 DIFAHVSQVSNNSGIEWVRRHLAPKGIRVHALNFVDPKPMH-IDTTLFTPRPGVAITCPD 423
DI ++ + + +E +RR+ A GIR+H++ ++ +H + L +PG+ I C D
Sbjct: 76 DIDQPIADPVSRTQVETLRRNCAEFGIRLHSMGDIEQGIVHVVGPQLGLTQPGMTIVCGD 135
Query: 424 RPCLQIGLF 450
G F
Sbjct: 136 SHTSTHGAF 144
>sp|Q7TXH6|LEU2_MYCBO 3-isopropylmalate dehydratase large subunit (Isopropylmalate
isomerase) (Alpha-IPM isomerase) (IPMI)
Length = 473
Score = 32.7 bits (73), Expect = 1.3
Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +1
Query: 247 DIFAHVSQVSNNSGIEWVRRHLAPKGIRVHALNFVDPKPMH-IDTTLFTPRPGVAITCPD 423
DI ++ + + +E +RR+ A GIR+H++ ++ +H + L +PG+ I C D
Sbjct: 76 DIDQPIADPVSRTQVETLRRNCAEFGIRLHSMGDIEQGIVHVVGPQLGLTQPGMTIVCGD 135
Query: 424 RPCLQIGLF 450
G F
Sbjct: 136 SHTSTHGAF 144
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,004,000
Number of Sequences: 369166
Number of extensions: 2052879
Number of successful extensions: 5484
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5269
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5461
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8486520240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)