Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_P08
(819 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P98196|AT11A_HUMAN Probable phospholipid-transporting AT... 234 3e-61
sp|P98197|AT11A_MOUSE Probable phospholipid-transporting AT... 232 1e-60
sp|Q9Y2G3|AT11B_HUMAN Probable phospholipid-transporting AT... 232 1e-60
sp|Q8NB49|AT11C_HUMAN Probable phospholipid-transporting AT... 224 2e-58
sp|Q9N0Z4|AT11B_RABIT Probable phospholipid-transporting AT... 219 9e-57
sp|Q9QZW0|AT11C_MOUSE Probable phospholipid-transporting AT... 204 2e-52
sp|Q9SGG3|ALA5_ARATH Putative phospholipid-transporting ATP... 202 9e-52
sp|Q8TF62|AT8B4_HUMAN Probable phospholipid-transporting AT... 202 1e-51
sp|Q9LNQ4|ALA4_ARATH Putative phospholipid-transporting ATP... 200 4e-51
sp|Q9Y2Q0|AT8A1_HUMAN Probable phospholipid-transporting AT... 196 8e-50
>sp|P98196|AT11A_HUMAN Probable phospholipid-transporting ATPase IH (ATPase class I type
11A) (ATPase IS)
Length = 1134
Score = 234 bits (596), Expect = 3e-61
Identities = 123/260 (47%), Positives = 172/260 (66%), Gaps = 7/260 (2%)
Frame = +3
Query: 57 YCLIVDGAALKYLLEPALEDD-------FIQLCMQVSTVLCCRMTPLQKAEIVALIKENV 215
Y LI+DGAAL +++P + F+++C S VLCCRM PLQKA+IV LIK +
Sbjct: 756 YGLIIDGAALSLIMKpreDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFS- 814
Query: 216 KPEPVTAAIGDGGNDVSMIQEAHVGLGIFGKEGRQAVRAADYAFGKFRFLRRLILIHGHF 395
K P+T AIGDG NDVSMI EAHVG+G+ GKEGRQA R +DYA KF+ L++++L+HGHF
Sbjct: 815 KEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHF 874
Query: 396 YYSRITNLIQYFFYKNLVFIAPQFYFAFINLYSAQPIYYTYILAVYNLTFTTLPVLLYGV 575
YY RI+ L+QYFFYKN+ FI PQF + F +S Q +Y T L +YN++FT+LP+LLY +
Sbjct: 875 YYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSL 934
Query: 576 FEQCLSKRELIAKPYLYKINKDNFILKLSNFVKWNINGVWHSLLIFLGIYTFTYLNGSVC 755
EQ + L P LY+ N +L+ F+ W + G++ +L+ F G Y F + N +V
Sbjct: 935 MEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVFFFGAY-FVFENTTVT 993
Query: 756 SQDGRNNPLEFFGEIVFILV 815
S +G+ FG +VF ++
Sbjct: 994 S-NGQIFGNWTFGTLVFTVM 1012
>sp|P98197|AT11A_MOUSE Probable phospholipid-transporting ATPase IH (ATPase class I type
11A) (ATPase IS)
Length = 1187
Score = 232 bits (591), Expect = 1e-60
Identities = 123/261 (47%), Positives = 171/261 (65%), Gaps = 8/261 (3%)
Frame = +3
Query: 57 YCLIVDGAALKYLLEPALEDD--------FIQLCMQVSTVLCCRMTPLQKAEIVALIKEN 212
Y LI+DGAAL +++P + F+++C S VLCCRM PLQKA+IV LIK +
Sbjct: 758 YGLIIDGAALSLIMKpreDGSSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKFS 817
Query: 213 VKPEPVTAAIGDGGNDVSMIQEAHVGLGIFGKEGRQAVRAADYAFGKFRFLRRLILIHGH 392
K P+T AIGDG NDVSMI EAHVG+G+ GKEGRQA R +DYA KF+ L++++L+HGH
Sbjct: 818 -KEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGH 876
Query: 393 FYYSRITNLIQYFFYKNLVFIAPQFYFAFINLYSAQPIYYTYILAVYNLTFTTLPVLLYG 572
FYY RI+ L+QYFFYKN+ FI PQF + F +S Q +Y T L +YN++FT+LP+LLY
Sbjct: 877 FYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYS 936
Query: 573 VFEQCLSKRELIAKPYLYKINKDNFILKLSNFVKWNINGVWHSLLIFLGIYTFTYLNGSV 752
+ EQ + L P LY+ N +L+ F+ W GV+ +L+ F G Y F + N +V
Sbjct: 937 LMEQHVGIDVLKRDPTLYRDIAKNALLRWRVFIYWTFLGVFDALVFFFGAY-FIFENTTV 995
Query: 753 CSQDGRNNPLEFFGEIVFILV 815
+ +G+ FG +VF ++
Sbjct: 996 -TINGQMFGNWTFGTLVFTVM 1015
>sp|Q9Y2G3|AT11B_HUMAN Probable phospholipid-transporting ATPase IF (ATPase class I type
11B) (ATPase IR)
Length = 1177
Score = 232 bits (591), Expect = 1e-60
Identities = 119/252 (47%), Positives = 163/252 (64%), Gaps = 1/252 (0%)
Frame = +3
Query: 63 LIVDGAALKYLLEPALEDDFIQLCMQVSTVLCCRMTPLQKAEIVALIKENVKPE-PVTAA 239
L+VDG +L L E F+++C S VLCCRM PLQKA+++ LIK + PE P+T A
Sbjct: 762 LVVDGTSLSLALREH-EKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIK--ISPEKPITLA 818
Query: 240 IGDGGNDVSMIQEAHVGLGIFGKEGRQAVRAADYAFGKFRFLRRLILIHGHFYYSRITNL 419
+GDG NDVSMIQEAHVG+GI GKEGRQA R +DYA +F+FL +L+ +HGHFYY RI L
Sbjct: 819 VGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATL 878
Query: 420 IQYFFYKNLVFIAPQFYFAFINLYSAQPIYYTYILAVYNLTFTTLPVLLYGVFEQCLSKR 599
+QYFFYKN+ FI PQF + F L+S Q +Y + L +YN+ FT+LP+L+Y + EQ +
Sbjct: 879 VQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPH 938
Query: 600 ELIAKPYLYKINKDNFILKLSNFVKWNINGVWHSLLIFLGIYTFTYLNGSVCSQDGRNNP 779
L KP LY+ N +L + F+ W I G H+ + F G Y + S+ +G+
Sbjct: 939 VLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLG-NGQMFG 997
Query: 780 LEFFGEIVFILV 815
FG +VF ++
Sbjct: 998 NWTFGTLVFTVM 1009
>sp|Q8NB49|AT11C_HUMAN Probable phospholipid-transporting ATPase IG (ATPase class I type
11C) (ATPase IG) (ATPase IQ) (ATPase class VI type 11C)
Length = 1132
Score = 224 bits (572), Expect = 2e-58
Identities = 117/260 (45%), Positives = 165/260 (63%), Gaps = 7/260 (2%)
Frame = +3
Query: 57 YCLIVDGAALKYLLEPALEDD-------FIQLCMQVSTVLCCRMTPLQKAEIVALIKENV 215
Y LI+DG+ L +L + + F+Q+CM+ + VLCCRM PLQKA+IV ++K N+
Sbjct: 750 YGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVK-NL 808
Query: 216 KPEPVTAAIGDGGNDVSMIQEAHVGLGIFGKEGRQAVRAADYAFGKFRFLRRLILIHGHF 395
K P+T +IGDG NDVSMI E+HVG+GI GKEGRQA R +DY+ KF+ L++L+L HGH
Sbjct: 809 KGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHL 868
Query: 396 YYSRITNLIQYFFYKNLVFIAPQFYFAFINLYSAQPIYYTYILAVYNLTFTTLPVLLYGV 575
YY RI +L+QYFFYKNL FI PQF + F +S QP+Y L +YN+ FT+LP+L Y +
Sbjct: 869 YYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSL 928
Query: 576 FEQCLSKRELIAKPYLYKINKDNFILKLSNFVKWNINGVWHSLLIFLGIYTFTYLNGSVC 755
EQ ++ L + P LY N +L+L F+ W + + F G Y F + S+
Sbjct: 929 LEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTY-FLFQTASL- 986
Query: 756 SQDGRNNPLEFFGEIVFILV 815
++G+ FG IVF ++
Sbjct: 987 EENGKVYGNWTFGTIVFTVL 1006
>sp|Q9N0Z4|AT11B_RABIT Probable phospholipid-transporting ATPase IF (ATPase class I type
11B) (ATPase IR) (RING-finger binding protein)
Length = 1169
Score = 219 bits (557), Expect = 9e-57
Identities = 115/252 (45%), Positives = 157/252 (62%), Gaps = 1/252 (0%)
Frame = +3
Query: 63 LIVDGAALKYLLEPALEDDFIQLCMQVSTVLCCRMTPLQKAEIVALIKENVKPE-PVTAA 239
L+VDG +L L E F+++C S VLCCRM PLQKA+++ LIK + PE P+T
Sbjct: 754 LVVDGTSLSLALREH-EKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIK--ISPEKPITIG 810
Query: 240 IGDGGNDVSMIQEAHVGLGIFGKEGRQAVRAADYAFGKFRFLRRLILIHGHFYYSRITNL 419
DG NDVSMIQEAHVG+GI GKE RQA R +DYA +F+FL +L+ +HGHFYY RI L
Sbjct: 811 CWDGANDVSMIQEAHVGIGIMGKERRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATL 870
Query: 420 IQYFFYKNLVFIAPQFYFAFINLYSAQPIYYTYILAVYNLTFTTLPVLLYGVFEQCLSKR 599
+QYFFYKN+ FI PQF + F L+S Q +Y + L +YN+ FT+LP+L+Y + EQ +
Sbjct: 871 VQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHIDPH 930
Query: 600 ELIAKPYLYKINKDNFILKLSNFVKWNINGVWHSLLIFLGIYTFTYLNGSVCSQDGRNNP 779
L KP LY+ N +L + F+ W I G S + G Y + S+ +G+
Sbjct: 931 ILQNKPTLYRDISKNRLLSIKTFLYWTILGFSRSFIFLFGSYFLIGKDASLLG-NGQMFG 989
Query: 780 LEFFGEIVFILV 815
FG +VF ++
Sbjct: 990 NWTFGTLVFTVM 1001
>sp|Q9QZW0|AT11C_MOUSE Probable phospholipid-transporting ATPase 11C
Length = 347
Score = 204 bits (519), Expect = 2e-52
Identities = 106/232 (45%), Positives = 149/232 (64%)
Frame = +3
Query: 120 FIQLCMQVSTVLCCRMTPLQKAEIVALIKENVKPEPVTAAIGDGGNDVSMIQEAHVGLGI 299
F+Q+CM+ + V+CC PLQKA+IV ++K N+K P+T +IGDG NDVSMI E+HVG+G
Sbjct: 9 FLQICMKCTAVVCCADQPLQKAQIVRMVK-NLKGSPITLSIGDGANDVSMILESHVGIG- 66
Query: 300 FGKEGRQAVRAADYAFGKFRFLRRLILIHGHFYYSRITNLIQYFFYKNLVFIAPQFYFAF 479
KEGRQA R +DY+ KF+ L++L+L+HGH YY RI +L+QYFFYKNL FI PQF + F
Sbjct: 67 --KEGRQAARNSDYSVPKFKHLKKLLLVHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQF 124
Query: 480 INLYSAQPIYYTYILAVYNLTFTTLPVLLYGVFEQCLSKRELIAKPYLYKINKDNFILKL 659
+S QP+Y L +YN+ FT+LP+L Y + EQ ++ L A P LY N +L+L
Sbjct: 125 FCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTADPRLYMKITGNAMLQL 184
Query: 660 SNFVKWNINGVWHSLLIFLGIYTFTYLNGSVCSQDGRNNPLEFFGEIVFILV 815
F+ W + + F G Y F + S+ +G+ FG IVF ++
Sbjct: 185 GPFLHWTFLAAFEGTVFFFGTY-FLFQTSSL-EDNGKIYGNWTFGTIVFTVL 234
>sp|Q9SGG3|ALA5_ARATH Putative phospholipid-transporting ATPase 5 (Aminophospholipid
flippase 5)
Length = 1228
Score = 202 bits (514), Expect = 9e-52
Identities = 108/243 (44%), Positives = 149/243 (61%), Gaps = 1/243 (0%)
Frame = +3
Query: 51 AAYCLIVDGAALKYLLEPALEDDFIQLCMQVSTVLCCRMTPLQKAEIVALIKENVKPEPV 230
AA+ LI+DG L Y LE ++ F+ L + ++V+CCR++P QKA +V L+KE
Sbjct: 816 AAFALIIDGKTLTYALEDDMKYQFLALAVDCASVICCRVSPKQKALVVRLVKEGTGK--T 873
Query: 231 TAAIGDGGNDVSMIQEAHVGLGIFGKEGRQAVRAADYAFGKFRFLRRLILIHGHFYYSRI 410
T AIGDG NDV MIQEA +G+GI G EG QAV A+D++ +FRFL RL+++HGH+ Y RI
Sbjct: 874 TLAIGDGANDVGMIQEADIGVGISGVEGMQAVMASDFSIAQFRFLERLLVVHGHWCYKRI 933
Query: 411 TNLIQYFFYKNLVFIAPQFYFAFINLYSAQPIYYTYILAVYNLTFTTLPVLLYGVFEQCL 590
+I YFFYKN+ F FYF +S Q +Y Y L ++N+ T+LPV+ GVFEQ +
Sbjct: 934 AQMICYFFYKNIAFGLTLFYFEAFTGFSGQSVYNDYYLLLFNVVLTSLPVIALGVFEQDV 993
Query: 591 SKRELIAKPYLYKINKDNFILKLSNFVKWNINGVWHSLLIFLGIYTFTYLN-GSVCSQDG 767
S + P LY+ N S + W NGV+ SL+IF +LN G + SQ
Sbjct: 994 SSEICLQFPALYQQGTKNLFFDWSRILGWMCNGVYASLVIF-------FLNIGIIYSQAF 1046
Query: 768 RNN 776
R+N
Sbjct: 1047 RDN 1049
>sp|Q8TF62|AT8B4_HUMAN Probable phospholipid-transporting ATPase IM (ATPase class I type 8B
member 4)
Length = 1192
Score = 202 bits (513), Expect = 1e-51
Identities = 100/239 (41%), Positives = 156/239 (65%)
Frame = +3
Query: 57 YCLIVDGAALKYLLEPALEDDFIQLCMQVSTVLCCRMTPLQKAEIVALIKENVKPEPVTA 236
Y LI++G +L + LE +++D ++L TV+CCR+TPLQKA++V L+K+ VT
Sbjct: 754 YALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKY--RNAVTL 811
Query: 237 AIGDGGNDVSMIQEAHVGLGIFGKEGRQAVRAADYAFGKFRFLRRLILIHGHFYYSRITN 416
AIGDG NDVSMI+ AH+G+GI G+EG QAV A+DY+F +FR+L+RL+L+HG + Y R+
Sbjct: 812 AIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCK 871
Query: 417 LIQYFFYKNLVFIAPQFYFAFINLYSAQPIYYTYILAVYNLTFTTLPVLLYGVFEQCLSK 596
+ YFFYKN F F+F F +SAQ +Y + + ++N+ +T+LPVL G+F+Q +S
Sbjct: 872 FLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSD 931
Query: 597 RELIAKPYLYKINKDNFILKLSNFVKWNINGVWHSLLIFLGIYTFTYLNGSVCSQDGRN 773
+ + P LYK + N + F ++G++ SL++F Y Y +V +DG++
Sbjct: 932 QNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFY---NVAGEDGQH 987
>sp|Q9LNQ4|ALA4_ARATH Putative phospholipid-transporting ATPase 4 (Aminophospholipid
flippase 4)
Length = 1216
Score = 200 bits (508), Expect = 4e-51
Identities = 100/221 (45%), Positives = 139/221 (62%)
Frame = +3
Query: 51 AAYCLIVDGAALKYLLEPALEDDFIQLCMQVSTVLCCRMTPLQKAEIVALIKENVKPEPV 230
AA+ LI+DG L Y LE ++ F+ L + ++V+CCR++P QKA + L+KE +
Sbjct: 804 AAFALIIDGKTLTYALEDEMKYQFLALAVDCASVICCRVSPKQKALVTRLVKEGTGK--I 861
Query: 231 TAAIGDGGNDVSMIQEAHVGLGIFGKEGRQAVRAADYAFGKFRFLRRLILIHGHFYYSRI 410
T AIGDG NDV MIQEA +G+GI G EG QAV A+D++ +FRFL RL+++HGH+ Y RI
Sbjct: 862 TLAIGDGANDVGMIQEADIGVGISGVEGMQAVMASDFSIAQFRFLERLLVVHGHWCYKRI 921
Query: 411 TNLIQYFFYKNLVFIAPQFYFAFINLYSAQPIYYTYILAVYNLTFTTLPVLLYGVFEQCL 590
+I YFFYKN+ F FYF +S Q +Y Y L ++N+ T+LPV+ GVFEQ +
Sbjct: 922 AQMICYFFYKNIAFGLTLFYFEAFTGFSGQSVYNDYYLLLFNVVLTSLPVIALGVFEQDV 981
Query: 591 SKRELIAKPYLYKINKDNFILKLSNFVKWNINGVWHSLLIF 713
S + P LY+ K N + W NGV+ SL+IF
Sbjct: 982 SSEICLQFPALYQQGKKNLFFDWYRILGWMGNGVYSSLVIF 1022
>sp|Q9Y2Q0|AT8A1_HUMAN Probable phospholipid-transporting ATPase IA (Chromaffin granule
ATPase II) (ATPase class I type 8A member 1)
Length = 1164
Score = 196 bits (497), Expect = 8e-50
Identities = 97/257 (37%), Positives = 155/257 (60%)
Frame = +3
Query: 45 KDAAYCLIVDGAALKYLLEPALEDDFIQLCMQVSTVLCCRMTPLQKAEIVALIKENVKPE 224
K+ + LI+DG LKY L + F+ L + V+CCR++PLQK+E+V ++K+ VK
Sbjct: 736 KENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKV- 794
Query: 225 PVTAAIGDGGNDVSMIQEAHVGLGIFGKEGRQAVRAADYAFGKFRFLRRLILIHGHFYYS 404
VT AIGDG NDVSMIQ AHVG+GI G EG QA ++DY+ +F++L+ L++IHG + Y+
Sbjct: 795 -VTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYN 853
Query: 405 RITNLIQYFFYKNLVFIAPQFYFAFINLYSAQPIYYTYILAVYNLTFTTLPVLLYGVFEQ 584
R++ I Y FYKN+V + +FAF+N +S Q ++ + + +YN+ FT +P L G+FE+
Sbjct: 854 RVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFER 913
Query: 585 CLSKRELIAKPYLYKINKDNFILKLSNFVKWNINGVWHSLLIFLGIYTFTYLNGSVCSQD 764
K ++ P LYK +++ F +NG++HS+++F + L +
Sbjct: 914 SCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFW--FPLKALQYGTAFGN 971
Query: 765 GRNNPLEFFGEIVFILV 815
G+ + G V+ V
Sbjct: 972 GKTSDYLLLGNFVYTFV 988
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,329,604
Number of Sequences: 369166
Number of extensions: 1811587
Number of successful extensions: 5258
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5022
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5200
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7859674995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)