Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_P07-2
(572 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q26551|PPIB_SCHMA Peptidyl-prolyl cis-trans isomerase B ... 218 1e-56
sp|Q27774|PPIB_SCHJA Peptidyl-prolyl cis-trans isomerase B ... 208 7e-54
sp|P52013|CYP5_CAEEL Peptidyl-prolyl cis-trans isomerase 5 ... 202 4e-52
sp|P24367|PPIB_CHICK Peptidyl-prolyl cis-trans isomerase B ... 199 5e-51
sp|P45877|PPIC_HUMAN Peptidyl-prolyl cis-trans isomerase C ... 197 2e-50
sp|P24369|PPIB_MOUSE Peptidyl-prolyl cis-trans isomerase B ... 196 3e-50
sp|P30412|PPIC_MOUSE Peptidyl-prolyl cis-trans isomerase C ... 195 6e-50
sp|P23284|PPIB_HUMAN Peptidyl-prolyl cis-trans isomerase B ... 195 8e-50
sp|P80311|PPIB_BOVIN Peptidyl-prolyl cis-trans isomerase B ... 194 2e-49
sp|P24368|PPIB_RAT Peptidyl-prolyl cis-trans isomerase B pr... 193 3e-49
>sp|Q26551|PPIB_SCHMA Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin)
Length = 213
Score = 218 bits (554), Expect = 1e-56
Identities = 102/150 (68%), Positives = 118/150 (78%)
Frame = +1
Query: 85 GPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGSKF 264
GPKVTDKVFFDIE+DGK + +I+IGLFGKTVPKTV NFK ++ G + DG+ +YKGS F
Sbjct: 27 GPKVTDKVFFDIEVDGKPLARIIIGLFGKTVPKTVENFKQLSIGTQLKDGRTASYKGSTF 86
Query: 265 HRVIKDFMLQXXXXXXXXXXXXISIYGDKFPDENFKLNHYGSGWLSMANAGPDTNGSQFF 444
HRVIK FM+Q SIYGD+FPDENFKL H G+GWLSMANAGPDTNGSQFF
Sbjct: 87 HRVIKSFMIQGGDFTNHDGTGGFSIYGDRFPDENFKLRHVGAGWLSMANAGPDTNGSQFF 146
Query: 445 ITVKDTPWLNGRHVVFGKVLEGMNVVRMIE 534
IT T WL+G+HVVFGKV+EGMN+VR IE
Sbjct: 147 ITTVKTSWLDGKHVVFGKVVEGMNIVRQIE 176
>sp|Q27774|PPIB_SCHJA Peptidyl-prolyl cis-trans isomerase B precursor (PPIase B)
(Rotamase B) (Cyclophilin B) (S-cyclophilin)
Length = 213
Score = 208 bits (530), Expect = 7e-54
Identities = 97/150 (64%), Positives = 116/150 (77%)
Frame = +1
Query: 85 GPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGSKF 264
GPKVT+KVFFDIE+D + +G+I+IGLFGKTVPKTV NFK ++ G DG+ YKGS F
Sbjct: 27 GPKVTEKVFFDIEVDEQPLGRIIIGLFGKTVPKTVENFKQLSIGTTLKDGRTAAYKGSTF 86
Query: 265 HRVIKDFMLQXXXXXXXXXXXXISIYGDKFPDENFKLNHYGSGWLSMANAGPDTNGSQFF 444
HRVIK FM+Q SIYG++FPDENFKL H G+GWLSMANAGP+TNG+QFF
Sbjct: 87 HRVIKSFMIQGGDFTNHDGTGGFSIYGERFPDENFKLKHVGAGWLSMANAGPNTNGAQFF 146
Query: 445 ITVKDTPWLNGRHVVFGKVLEGMNVVRMIE 534
IT PWL+G+HVVFGKV+EGM+VVR IE
Sbjct: 147 ITTTQNPWLDGKHVVFGKVVEGMSVVRQIE 176
>sp|P52013|CYP5_CAEEL Peptidyl-prolyl cis-trans isomerase 5 precursor (PPIase) (Rotamase)
(Cyclophilin-5)
Length = 204
Score = 202 bits (515), Expect = 4e-52
Identities = 102/151 (67%), Positives = 114/151 (75%)
Frame = +1
Query: 82 KGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGSK 261
KGPKVTDKV+FD+EI GK +G+IVIGLFGKTVPKT TNF +A+ K Y GSK
Sbjct: 23 KGPKVTDKVYFDMEIGGKPIGRIVIGLFGKTVPKTATNFIELAKKPKGEG-----YPGSK 77
Query: 262 FHRVIKDFMLQXXXXXXXXXXXXISIYGDKFPDENFKLNHYGSGWLSMANAGPDTNGSQF 441
FHRVI DFM+Q SIYG+KF DENFKL HYG+GWLSMANAG DTNGSQF
Sbjct: 78 FHRVIADFMIQGGDFTRGDGTGGRSIYGEKFADENFKLKHYGAGWLSMANAGADTNGSQF 137
Query: 442 FITVKDTPWLNGRHVVFGKVLEGMNVVRMIE 534
FIT TPWL+GRHVVFGK+LEGM+VVR IE
Sbjct: 138 FITTVKTPWLDGRHVVFGKILEGMDVVRKIE 168
>sp|P24367|PPIB_CHICK Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin) (SCYLP)
Length = 207
Score = 199 bits (505), Expect = 5e-51
Identities = 98/152 (64%), Positives = 114/152 (75%)
Frame = +1
Query: 79 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 258
KKGPKVT KVFFD+ + ++ G++VIGLFGKTVPKTV NF ++A G K +KGS
Sbjct: 28 KKGPKVTAKVFFDLRVGEEDAGRVVIGLFGKTVPKTVENFVALATGEKG-----FGFKGS 82
Query: 259 KFHRVIKDFMLQXXXXXXXXXXXXISIYGDKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 438
KFHRVIKDFM+Q SIYGD+FPDENFKL HYG GW+SMANAG DTNGSQ
Sbjct: 83 KFHRVIKDFMIQGGDFTRGDGTGGKSIYGDRFPDENFKLKHYGPGWVSMANAGKDTNGSQ 142
Query: 439 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIE 534
FFIT T WL+G+HVVFGKVLEGM+VVR +E
Sbjct: 143 FFITTVKTAWLDGKHVVFGKVLEGMDVVRKVE 174
>sp|P45877|PPIC_HUMAN Peptidyl-prolyl cis-trans isomerase C (PPIase) (Rotamase)
(Cyclophilin C)
Length = 212
Score = 197 bits (501), Expect = 2e-50
Identities = 97/153 (63%), Positives = 113/153 (73%)
Frame = +1
Query: 79 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 258
K+GP VT KVFFD+ I K+VG+IVIGLFGK VPKTV NF ++A G K YKGS
Sbjct: 31 KRGPSVTAKVFFDVRIGDKDVGRIVIGLFGKVVPKTVENFVALATGEKGYG-----YKGS 85
Query: 259 KFHRVIKDFMLQXXXXXXXXXXXXISIYGDKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 438
KFHRVIKDFM+Q +SIYG+ FPDENFKL HYG GW+SMANAGPDTNGSQ
Sbjct: 86 KFHRVIKDFMIQGGDITTGDGTGGVSIYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQ 145
Query: 439 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIEI 537
FFIT+ WL+G+HVVFGKV++GM VV IE+
Sbjct: 146 FFITLTKPTWLDGKHVVFGKVIDGMTVVHSIEL 178
>sp|P24369|PPIB_MOUSE Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1)
Length = 208
Score = 196 bits (499), Expect = 3e-50
Identities = 97/152 (63%), Positives = 114/152 (75%)
Frame = +1
Query: 79 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 258
KKGPKVT KV+FD++I ++VG++V GLFGKTVPKTV NF ++A G K YK S
Sbjct: 29 KKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKG-----FGYKNS 83
Query: 259 KFHRVIKDFMLQXXXXXXXXXXXXISIYGDKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 438
KFHRVIKDFM+Q SIYG++FPDENFKL HYG GW+SMANAG DTNGSQ
Sbjct: 84 KFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQ 143
Query: 439 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIE 534
FFIT T WL+G+HVVFGKVLEGM+VVR +E
Sbjct: 144 FFITTVKTSWLDGKHVVFGKVLEGMDVVRKVE 175
>sp|P30412|PPIC_MOUSE Peptidyl-prolyl cis-trans isomerase C (PPIase) (Rotamase)
(Cyclophilin C)
Length = 212
Score = 195 bits (496), Expect = 6e-50
Identities = 97/153 (63%), Positives = 112/153 (73%)
Frame = +1
Query: 79 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 258
K+GP VTDKVFFD+ I K+VG+IVIGLFG VPKTV NF ++A G K YKGS
Sbjct: 31 KRGPSVTDKVFFDVRIGDKDVGRIVIGLFGNVVPKTVENFVALATGEKGYG-----YKGS 85
Query: 259 KFHRVIKDFMLQXXXXXXXXXXXXISIYGDKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 438
FHRVIKDFM+Q +SIYG+ FPDENFKL HYG GW+SMANAGPDTNGSQ
Sbjct: 86 IFHRVIKDFMIQGGDFTARDGTGGMSIYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQ 145
Query: 439 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIEI 537
FFIT+ WL+G+HVVFGKVL+GM VV IE+
Sbjct: 146 FFITLTKPTWLDGKHVVFGKVLDGMTVVHSIEL 178
>sp|P23284|PPIB_HUMAN Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1)
Length = 208
Score = 195 bits (495), Expect = 8e-50
Identities = 96/152 (63%), Positives = 112/152 (73%)
Frame = +1
Query: 79 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 258
KKGPKVT KV+FD+ I ++VG+++ GLFGKTVPKTV NF ++A G K YK S
Sbjct: 29 KKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKG-----FGYKNS 83
Query: 259 KFHRVIKDFMLQXXXXXXXXXXXXISIYGDKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 438
KFHRVIKDFM+Q SIYG++FPDENFKL HYG GW+SMANAG DTNGSQ
Sbjct: 84 KFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQ 143
Query: 439 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIE 534
FFIT T WL+G+HVVFGKVLEGM VVR +E
Sbjct: 144 FFITTVKTAWLDGKHVVFGKVLEGMEVVRKVE 175
>sp|P80311|PPIB_BOVIN Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin) (SCYLP)
Length = 208
Score = 194 bits (492), Expect = 2e-49
Identities = 96/152 (63%), Positives = 113/152 (74%)
Frame = +1
Query: 79 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 258
KKGPKVT KV+FD+ I +++G++VIGLFGKTVPKTV NF ++A G K YK S
Sbjct: 29 KKGPKVTVKVYFDLRIGDEDIGRVVIGLFGKTVPKTVDNFVALATGEKG-----FGYKDS 83
Query: 259 KFHRVIKDFMLQXXXXXXXXXXXXISIYGDKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 438
KFHRVIKDFM+Q SIYG++FPDENFKL HYG GW+SMANAG DTNGSQ
Sbjct: 84 KFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQ 143
Query: 439 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIE 534
FFIT T WL+G+HV FGKVLEGM+VVR +E
Sbjct: 144 FFITTVKTAWLDGKHVGFGKVLEGMDVVRKVE 175
>sp|P24368|PPIB_RAT Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1)
Length = 208
Score = 193 bits (490), Expect = 3e-49
Identities = 96/152 (63%), Positives = 111/152 (73%)
Frame = +1
Query: 79 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 258
KKGPKVT KV+FD +I + VG++ GLFGKTVPKTV NF ++A G K YK S
Sbjct: 29 KKGPKVTVKVYFDFQIGDEPVGRVTFGLFGKTVPKTVDNFVALATGEKG-----FGYKNS 83
Query: 259 KFHRVIKDFMLQXXXXXXXXXXXXISIYGDKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 438
KFHRVIKDFM+Q SIYG++FPDENFKL HYG GW+SMANAG DTNGSQ
Sbjct: 84 KFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQ 143
Query: 439 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIE 534
FFIT T WL+G+HVVFGKVLEGM+VVR +E
Sbjct: 144 FFITTVKTSWLDGKHVVFGKVLEGMDVVRKVE 175
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,234,726
Number of Sequences: 369166
Number of extensions: 1149995
Number of successful extensions: 2952
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2765
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2825
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4226258440
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)