Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_O14
(905 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q01406|SRC8_CHICK Src substrate protein p85 (p80) (Corta... 350 3e-96
sp|Q60598|SRC8_MOUSE Src substrate cortactin 347 3e-95
sp|Q14247|SRC8_HUMAN Src substrate cortactin (Amplaxin) (On... 346 6e-95
sp|P49710|HCLS1_MOUSE Hematopoietic lineage cell-specific p... 248 2e-65
sp|P14317|HCLS1_HUMAN Hematopoietic lineage cell-specific p... 246 6e-65
sp|Q6XPR3|RPTN_HUMAN Repetin 48 4e-05
sp|Q86YZ3|HORN_HUMAN Hornerin 45 4e-04
sp|O76743|GLH4_CAEEL ATP-dependent RNA helicase glh-4 (Germ... 38 0.045
sp|P34857|NU6M_APILI NADH-ubiquinone oxidoreductase chain 6... 37 0.076
sp|Q28092|CYLC2_BOVIN Cylicin-2 (Cylicin II) (Multiple-band... 37 0.099
>sp|Q01406|SRC8_CHICK Src substrate protein p85 (p80) (Cortactin)
Length = 563
Score = 350 bits (898), Expect = 3e-96
Identities = 167/290 (57%), Positives = 216/290 (74%)
Frame = +3
Query: 36 INMWKATAGSXXXXXXXXXXXXXXXXXXXXFQNDVTEKEQRWGSKTVSGSGRTDFIDLSA 215
+ MWKATAG F NDV+EKEQRWG+KTV GSG + I++
Sbjct: 9 LQMWKATAGHSIAVSQDDGADDWETDPD--FVNDVSEKEQRWGAKTVKGSGHQEHINIHQ 66
Query: 216 LKESVKKSDADNKKIAYDRSSKPSYGYGGSFGVQKDRMDKCAVGNDYVAAVDKHTSQKDY 395
L+E+V + K+ + K S+GYGG FGV++DRMDK AVG++Y + + KH SQ D
Sbjct: 67 LRENVFQEHQTIKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDS 126
Query: 396 SQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVGWE 575
+GFGGK+GVQ+DR D+SA G+EYQ + +KH SQ+DYS GFGGKYGVQ DR DK+AVG++
Sbjct: 127 VKGFGGKFGVQTDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFD 186
Query: 576 HKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYG 755
++ + EKH SQKDYS+GFGGK+GV K++ DKSAVG+E++ +TEKH SQ+DY KGFGGK+G
Sbjct: 187 YQGKTEKHESQKDYSKGFGGKYGVDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFG 246
Query: 756 VQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGW 905
VQTDRQDKCA+GW+H+E++ H SQ+DY GFGGKFGVQ ERQD SAVG+
Sbjct: 247 VQTDRQDKCALGWDHQEKVQLHESQKDYKSGFGGKFGVQTERQDPSAVGF 296
Score = 249 bits (635), Expect = 1e-65
Identities = 120/213 (56%), Positives = 149/213 (69%)
Frame = +3
Query: 171 TVSGSGRTDFIDLSALKESVKKSDADNKKIAYDRSSKPSYGYGGSFGVQKDRMDKCAVGN 350
+V G G + + +S + K + S G+GG +GVQ DR+DK AVG
Sbjct: 126 SVKGFGGKFGVQTDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGF 185
Query: 351 DYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKY 530
DY +KH SQKDYS+GFGGKYGV D+ DKSA G+EYQ + +KH SQ+DY KGFGGK+
Sbjct: 186 DYQGKTEKHESQKDYSKGFGGKYGVDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKF 245
Query: 531 GVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKH 710
GVQ DRQDK A+GW+H+ +++ H SQKDY GFGGKFGVQ ERQD SAVG+++KE+ KH
Sbjct: 246 GVQTDRQDKCALGWDHQEKVQLHESQKDYKSGFGGKFGVQTERQDPSAVGFDYKEKLAKH 305
Query: 711 GSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEE 809
SQQDYSKGFGGKYGVQ DR DK A +E E+
Sbjct: 306 ESQQDYSKGFGGKYGVQKDRMDKNAATFEDIEK 338
>sp|Q60598|SRC8_MOUSE Src substrate cortactin
Length = 546
Score = 347 bits (890), Expect = 3e-95
Identities = 165/288 (57%), Positives = 214/288 (74%)
Frame = +3
Query: 42 MWKATAGSXXXXXXXXXXXXXXXXXXXXFQNDVTEKEQRWGSKTVSGSGRTDFIDLSALK 221
MWKA+AG F NDV+EKEQRWG+KTV GSG + I++ L+
Sbjct: 1 MWKASAGHAVSITQDDGGADDWETDPD-FVNDVSEKEQRWGAKTVQGSGHQEHINIHKLR 59
Query: 222 ESVKKSDADNKKIAYDRSSKPSYGYGGSFGVQKDRMDKCAVGNDYVAAVDKHTSQKDYSQ 401
E+V + K+ + K S+GYGG FGV++DRMD+ AVG++Y + + KH SQ D +
Sbjct: 60 ENVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDRSAVGHEYQSKLSKHCSQVDSVR 119
Query: 402 GFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVGWEHK 581
GFGGK+GVQ DR D+SA G+EYQ + +KH SQ+DYS GFGGKYGVQ DR DK+AVG++++
Sbjct: 120 GFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQ 179
Query: 582 AELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQ 761
+ EKH SQKDYS+GFGGK+G+ K++ DKSAVG+E++ +TEKH SQ+DY KGFGGK+GVQ
Sbjct: 180 GKTEKHESQKDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQ 239
Query: 762 TDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGW 905
TDRQDKCA+GW+H+E+L H SQ+DY GFGGKFGVQ ERQD SAVG+
Sbjct: 240 TDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSSAVGF 287
Score = 246 bits (627), Expect = 8e-65
Identities = 117/209 (55%), Positives = 146/209 (69%)
Frame = +3
Query: 171 TVSGSGRTDFIDLSALKESVKKSDADNKKIAYDRSSKPSYGYGGSFGVQKDRMDKCAVGN 350
+V G G + + + +S + K + S G+GG +GVQ DR+DK AVG
Sbjct: 117 SVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGF 176
Query: 351 DYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKY 530
DY +KH SQKDYS+GFGGKYG+ D+ DKSA G+EYQ + +KH SQ+DY KGFGGK+
Sbjct: 177 DYQGKTEKHESQKDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKF 236
Query: 531 GVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKH 710
GVQ DRQDK A+GW+H+ +L+ H SQKDY GFGGKFGVQ ERQD SAVG+++KE KH
Sbjct: 237 GVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSSAVGFDYKERLAKH 296
Query: 711 GSQQDYSKGFGGKYGVQTDRQDKCAVGWE 797
QQDY+KGFGGKYGVQ DR DK A +E
Sbjct: 297 EPQQDYAKGFGGKYGVQKDRMDKNASTFE 325
Score = 132 bits (333), Expect = 1e-30
Identities = 73/208 (35%), Positives = 107/208 (51%), Gaps = 19/208 (9%)
Frame = +3
Query: 168 KTVSGSGRTDFIDLSALKESVKKSDADNKKIAYDRSSKPSY---------GYGGSFGVQK 320
KT + D+ K + K D + ++ K G+GG FGVQ
Sbjct: 181 KTEKHESQKDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT 240
Query: 321 DRMDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQ 500
DR DKCA+G D+ + H SQKDY GFGGK+GVQS+R+D SA G++Y+ + KH QQ
Sbjct: 241 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSSAVGFDYKERLAKHEPQQ 300
Query: 501 DYSKGFGGKYGVQKDRQDKAAVGWEHKAE----------LEKHSSQKDYSQGFGGKFGVQ 650
DY+KGFGGKYGVQKDR DK A +E + +E +S+ + +
Sbjct: 301 DYAKGFGGKYGVQKDRMDKNASTFEEVVQVPSAYQKTVPIEAVTSKTSNIRANFENLAKE 360
Query: 651 KERQDKSAVGWEHKEETEKHGSQQDYSK 734
+E++D+ E + K +Q+ ++
Sbjct: 361 REQEDRRKAEAERAQRMAKERQEQEEAR 388
>sp|Q14247|SRC8_HUMAN Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Length = 550
Score = 346 bits (887), Expect = 6e-95
Identities = 164/288 (56%), Positives = 214/288 (74%)
Frame = +3
Query: 42 MWKATAGSXXXXXXXXXXXXXXXXXXXXFQNDVTEKEQRWGSKTVSGSGRTDFIDLSALK 221
MWKA+AG F NDV+EKEQRWG+KTV GSG + I++ L+
Sbjct: 1 MWKASAGHAVSIAQDDAGADDWETDPD-FVNDVSEKEQRWGAKTVQGSGHQEHINIHKLR 59
Query: 222 ESVKKSDADNKKIAYDRSSKPSYGYGGSFGVQKDRMDKCAVGNDYVAAVDKHTSQKDYSQ 401
E+V + K+ + K S+GYGG FGV++DRMDK AVG++Y + + KH SQ D +
Sbjct: 60 ENVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVR 119
Query: 402 GFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVGWEHK 581
GFGGK+GVQ DR D+SA G+EYQ + +KH SQ+DYS GFGGKYGVQ DR DK+AVG++++
Sbjct: 120 GFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQ 179
Query: 582 AELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQ 761
+ EKH SQ+DYS+GFGGK+G+ K++ DKSAVG+E++ +TEKH SQ+DY KGFGGK+GVQ
Sbjct: 180 GKTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQ 239
Query: 762 TDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGW 905
TDRQDKCA+GW+H+E+L H SQ+DY GFGGKFGVQ ERQD +AVG+
Sbjct: 240 TDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGF 287
Score = 247 bits (630), Expect = 4e-65
Identities = 117/209 (55%), Positives = 148/209 (70%)
Frame = +3
Query: 171 TVSGSGRTDFIDLSALKESVKKSDADNKKIAYDRSSKPSYGYGGSFGVQKDRMDKCAVGN 350
+V G G + + + +S + K + S G+GG +GVQ DR+DK AVG
Sbjct: 117 SVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGF 176
Query: 351 DYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKY 530
DY +KH SQ+DYS+GFGGKYG+ D+ DKSA G+EYQ + +KH SQ+DY KGFGGK+
Sbjct: 177 DYQGKTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKF 236
Query: 531 GVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKH 710
GVQ DRQDK A+GW+H+ +L+ H SQKDY GFGGKFGVQ ERQD +AVG+++KE+ KH
Sbjct: 237 GVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKH 296
Query: 711 GSQQDYSKGFGGKYGVQTDRQDKCAVGWE 797
SQQDYSKGFGGKYGVQ DR DK A +E
Sbjct: 297 ESQQDYSKGFGGKYGVQKDRMDKNASTFE 325
Score = 81.6 bits (200), Expect = 3e-15
Identities = 45/113 (39%), Positives = 60/113 (53%), Gaps = 9/113 (7%)
Frame = +3
Query: 168 KTVSGSGRTDFIDLSALKESVKKSDADNKKIAYDRSSKPSY---------GYGGSFGVQK 320
KT + D++ K V+ D + +D K G+GG FGVQ
Sbjct: 218 KTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQS 277
Query: 321 DRMDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEV 479
+R D AVG DY + KH SQ+DYS+GFGGKYGVQ DR DK+A+ +E +V
Sbjct: 278 ERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKNASTFEDVTQV 330
>sp|P49710|HCLS1_MOUSE Hematopoietic lineage cell-specific protein (Hematopoietic
cell-specific LYN substrate 1) (LckBP1)
Length = 486
Score = 248 bits (633), Expect = 2e-65
Identities = 111/190 (58%), Positives = 152/190 (80%)
Frame = +3
Query: 126 FQNDVTEKEQRWGSKTVSGSGRTDFIDLSALKESVKKSDADNKKIAYDRSSKPSYGYGGS 305
F ND++EKEQRWG+KT+ GSGRT+ I++ L+ V + KK + K S+GYGG
Sbjct: 27 FVNDISEKEQRWGAKTIEGSGRTEHINIHQLRNKVSEEHDILKKKELESGPKASHGYGGQ 86
Query: 306 FGVQKDRMDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQK 485
FGV++DRMDK AVG++YVA V+KH+SQ D ++GFGGKYGV+ DR DKSA G++Y+ EV+K
Sbjct: 87 FGVERDRMDKSAVGHEYVADVEKHSSQTDAARGFGGKYGVERDRADKSAVGFDYKGEVEK 146
Query: 486 HGSQQDYSKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQD 665
H SQ+DYS GFGG+YGV+KD++DKAA+G+++K E EKH SQ+DY++GFGG++G+QK+R D
Sbjct: 147 HASQKDYSHGFGGRYGVEKDKRDKAALGYDYKGETEKHESQRDYAKGFGGQYGIQKDRVD 206
Query: 666 KSAVGWEHKE 695
KSAVG+ E
Sbjct: 207 KSAVGFNEME 216
Score = 184 bits (468), Expect = 2e-46
Identities = 80/133 (60%), Positives = 115/133 (86%)
Frame = +3
Query: 507 SKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWE 686
S G+GG++GV++DR DK+AVG E+ A++EKHSSQ D ++GFGGK+GV+++R DKSAVG++
Sbjct: 80 SHGYGGQFGVERDRMDKSAVGHEYVADVEKHSSQTDAARGFGGKYGVERDRADKSAVGFD 139
Query: 687 HKEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFG 866
+K E EKH SQ+DYS GFGG+YGV+ D++DK A+G+++K E KH SQ+DY++GFGG++G
Sbjct: 140 YKGEVEKHASQKDYSHGFGGRYGVEKDKRDKAALGYDYKGETEKHESQRDYAKGFGGQYG 199
Query: 867 VQKERQDKSAVGW 905
+QK+R DKSAVG+
Sbjct: 200 IQKDRVDKSAVGF 212
>sp|P14317|HCLS1_HUMAN Hematopoietic lineage cell-specific protein (Hematopoietic
cell-specific LYN substrate 1) (LckBP1) (p75)
Length = 486
Score = 246 bits (628), Expect = 6e-65
Identities = 110/190 (57%), Positives = 152/190 (80%)
Frame = +3
Query: 126 FQNDVTEKEQRWGSKTVSGSGRTDFIDLSALKESVKKSDADNKKIAYDRSSKPSYGYGGS 305
F ND++EKEQRWG+KT+ GSGRT+ I++ L+ V + +K + K S+GYGG
Sbjct: 27 FVNDISEKEQRWGAKTIEGSGRTEHINIHQLRNKVSEEHDVLRKKEMESGPKASHGYGGR 86
Query: 306 FGVQKDRMDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQK 485
FGV++DRMDK AVG++YVA V+KH+SQ D ++GFGGKYGV+ DR DKSA G++Y+ EV+K
Sbjct: 87 FGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKGFGGKYGVERDRADKSAVGFDYKGEVEK 146
Query: 486 HGSQQDYSKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQD 665
H SQ+DYS+GFGG+YGV+KD+ DKAA+G+++K E EKH SQ+DY++GFGG++G+QK+R D
Sbjct: 147 HTSQKDYSRGFGGRYGVEKDKWDKAALGYDYKGETEKHESQRDYAKGFGGQYGIQKDRVD 206
Query: 666 KSAVGWEHKE 695
KSAVG+ E
Sbjct: 207 KSAVGFNEME 216
Score = 185 bits (470), Expect = 1e-46
Identities = 81/133 (60%), Positives = 115/133 (86%)
Frame = +3
Query: 507 SKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWE 686
S G+GG++GV++DR DK+AVG E+ AE+EKHSSQ D ++GFGGK+GV+++R DKSAVG++
Sbjct: 80 SHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKGFGGKYGVERDRADKSAVGFD 139
Query: 687 HKEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFG 866
+K E EKH SQ+DYS+GFGG+YGV+ D+ DK A+G+++K E KH SQ+DY++GFGG++G
Sbjct: 140 YKGEVEKHTSQKDYSRGFGGRYGVEKDKWDKAALGYDYKGETEKHESQRDYAKGFGGQYG 199
Query: 867 VQKERQDKSAVGW 905
+QK+R DKSAVG+
Sbjct: 200 IQKDRVDKSAVGF 212
>sp|Q6XPR3|RPTN_HUMAN Repetin
Length = 784
Score = 47.8 bits (112), Expect = 4e-05
Identities = 60/193 (31%), Positives = 86/193 (44%), Gaps = 19/193 (9%)
Frame = +3
Query: 375 HTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQ-KHGSQQDYSKGFGGKYGVQKDRQ 551
H Q D +Q YG Q+DR+D+S+ + + + Q H SQ D +G G YG Q DRQ
Sbjct: 378 HYGQPD-TQDQSSHYG-QTDRQDQSSHYGQTERQGQSSHYSQMD-RQGQGSHYG-QTDRQ 433
Query: 552 DKAA-VGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDY 728
+++ G + H Q D QG +G Q +RQ +S+ H + +K G Y
Sbjct: 434 GQSSHYGQPDRQGQNSHYGQTD-RQGQSSHYG-QTDRQGQSS----HYSQPDKQGQSSHY 487
Query: 729 SK----------------GFGGKYGVQTDRQDKC-AVGWEHKEELGKHASQQDYSQGFGG 857
K G YG QTDRQ + G ++ H SQ D QG
Sbjct: 488 GKIDRQDQSYHYGQPDGQGQSSHYG-QTDRQGQSFHYGQPDRQGQSSHYSQMD-RQGQSS 545
Query: 858 KFGVQKERQDKSA 896
+G Q +RQ +S+
Sbjct: 546 HYG-QTDRQGQSS 557
>sp|Q86YZ3|HORN_HUMAN Hornerin
Length = 2850
Score = 44.7 bits (104), Expect = 4e-04
Identities = 52/208 (25%), Positives = 71/208 (34%), Gaps = 21/208 (10%)
Frame = +3
Query: 285 SYGYGGSFGVQKDRMDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWE 464
S+G GS Q R + G+ + +H S +S +G + S +GW
Sbjct: 635 SHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYG---------QHGSGSGWS 685
Query: 465 YQAEVQKHGSQQDYSKGFGGKYGV-QKDRQDKAAVGWEHKAELEKH---------SSQKD 614
+ HGS S GFG K G Q + G H + KH S Q
Sbjct: 686 --SSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHG 743
Query: 615 YSQGFGGKFGV------QKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQD 776
S G +G Q + G H +HGS +S G++G T
Sbjct: 744 SSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSH-GQHGSGTSCSS 802
Query: 777 KCA---VGWEHKEELGKH--ASQQDYSQ 845
C G G+H S Q YSQ
Sbjct: 803 SCGHYESGSGQASGFGQHESGSGQGYSQ 830
Score = 39.7 bits (91), Expect = 0.012
Identities = 57/260 (21%), Positives = 86/260 (33%), Gaps = 29/260 (11%)
Frame = +3
Query: 162 GSKTVSGSGRTDFIDLSALKESVKKSDADNKKIAYDRSSKPSYGYG--GSFGVQKDRMDK 335
G + SG + + S S + + S S GYG GS Q R ++
Sbjct: 1619 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1678
Query: 336 CAVGNDYVAAVDKHTSQKDYSQGFG--GKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYS 509
+ + +H S S G G G QS + + +G + + +HGS
Sbjct: 1679 HGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS----G 1734
Query: 510 KGFGGKYGVQKDRQDKAAV------GWEHKAELEKHSSQKDY--SQGFGGKFGVQKERQD 665
G G + R ++V G H + +H S + SQG G Q D
Sbjct: 1735 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 1794
Query: 666 KSAVGWEHKEETEKHGSQQDYSKGFG------------GKYGVQTDR-----QDKCAVGW 794
+ +HGS S +G G++G + Q GW
Sbjct: 1795 QEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 1854
Query: 795 EHKEELGKHASQQDYSQGFG 854
G+H S S GFG
Sbjct: 1855 SSSS--GRHGSGSGQSSGFG 1872
Score = 37.4 bits (85), Expect = 0.058
Identities = 47/203 (23%), Positives = 73/203 (35%), Gaps = 8/203 (3%)
Frame = +3
Query: 264 YDRSSKPSYGYGG--SFGVQKDRMDKCAVGNDYVAAVDKH--TSQKDYSQGFGGKYGVQS 431
Y+ S + G+G S Q K G+ + ++ +H TS + S G G QS
Sbjct: 338 YESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQS 397
Query: 432 DRKDKSAAGWEYQAEVQKHGSQQDYSKGFG--GKYGVQKDRQDKAAVGWEHKAELEKHSS 605
+ + + + +H S S G G G Q + G+ + + S
Sbjct: 398 SSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVS 457
Query: 606 QKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFG--GKYGVQTDRQDK 779
YS GFG + S+ EH +HGS +S G G G Q+ R ++
Sbjct: 458 GSGYSSGFG--------HHESSS---EHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGER 506
Query: 780 CAVGWEHKEELGKHASQQDYSQG 848
G+H S S G
Sbjct: 507 QGSSAGSSSSYGQHGSGSRQSLG 529
Score = 37.4 bits (85), Expect = 0.058
Identities = 48/216 (22%), Positives = 72/216 (33%), Gaps = 27/216 (12%)
Frame = +3
Query: 288 YGYGGSFGVQKDRMDKCAVGNDYVAAVDKHTSQKDYSQGFG--GKYGVQSDRKDKSAAGW 461
YG GS Q R ++ + + +H S S G G G S + + +G
Sbjct: 2133 YGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGS 2192
Query: 462 EYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAV------GWEHKAELEKHSSQKDY-- 617
+ + +HGS G G + R ++V G H + +H S +
Sbjct: 2193 GHSSSHGQHGS----GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFC 2248
Query: 618 SQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFG------------GKYGVQ 761
SQG G Q D+ +HGS S +G G++G
Sbjct: 2249 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG 2308
Query: 762 TDR-----QDKCAVGWEHKEELGKHASQQDYSQGFG 854
+ Q GW G+H S S GFG
Sbjct: 2309 SGHSSSYGQHGSGSGWSSSS--GRHGSGSGQSSGFG 2342
Score = 36.2 bits (82), Expect = 0.13
Identities = 50/196 (25%), Positives = 69/196 (35%), Gaps = 4/196 (2%)
Frame = +3
Query: 285 SYGYGGSFGVQKDRMDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWE 464
SYG GS Q + G+ + + +H S +S G ++G S S+ G
Sbjct: 751 SYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHG-QHG--SGTSCSSSCGHY 807
Query: 465 YQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSS--QKDYSQGFGGK 638
Q G Q + G G Y + H + + SS Q D S G
Sbjct: 808 ESGSGQASGFGQ-HESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSS 866
Query: 639 FGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFG--GKYGVQTDRQDKCAVGWEHKEEL 812
+G Q +SA H +HGS S G G G Q+ + G
Sbjct: 867 YG-----QHESAS--HHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSS 919
Query: 813 GKHASQQDYSQGFGGK 860
G+H S S GFG K
Sbjct: 920 GRHGSGSGQSSGFGHK 935
Score = 36.2 bits (82), Expect = 0.13
Identities = 56/260 (21%), Positives = 84/260 (32%), Gaps = 29/260 (11%)
Frame = +3
Query: 162 GSKTVSGSGRTDFIDLSALKESVKKSDADNKKIAYDRSSKPSYGYG--GSFGVQKDRMDK 335
G + SG + + S S + + S S GYG GS Q R ++
Sbjct: 1149 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208
Query: 336 CAVGNDYVAAVDKHTSQKDYSQGFG--GKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYS 509
+ + +H S S G G G S + + +G + + +HGS
Sbjct: 1209 HGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGS----G 1264
Query: 510 KGFGGKYGVQKDRQDKAAV------GWEHKAELEKHSSQKDY--SQGFGGKFGVQKERQD 665
G G + R ++V G H + +H S + SQG G Q D
Sbjct: 1265 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 1324
Query: 666 KSAVGWEHKEETEKHGSQQDYSKGFG------------GKYGVQTDR-----QDKCAVGW 794
+ GS S G+G G++G + Q GW
Sbjct: 1325 QEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 1384
Query: 795 EHKEELGKHASQQDYSQGFG 854
G+H S S GFG
Sbjct: 1385 SSSS--GRHGSGSGQSSGFG 1402
Score = 34.7 bits (78), Expect = 0.38
Identities = 40/167 (23%), Positives = 58/167 (34%), Gaps = 2/167 (1%)
Frame = +3
Query: 372 KHTSQKDYSQGFGGKYGV--QSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKD 545
+ +S+ Y G G G+ Q R +S+ +HGS S G +G
Sbjct: 567 RSSSRGPYESGSGHSSGLGHQESRSGQSSG-------YGQHGS----SSGHSSTHGQHGS 615
Query: 546 RQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQD 725
+++ +H A +S + S G G Q R + G +HGS
Sbjct: 616 TSGQSSSCGQHGA-----TSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFG 670
Query: 726 YSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFG 866
+S +G Q GW G H S S GFG K G
Sbjct: 671 HSSSYG---------QHGSGSGWSSSN--GPHGSVSGQSSGFGHKSG 706
>sp|O76743|GLH4_CAEEL ATP-dependent RNA helicase glh-4 (Germline helicase 4)
Length = 1156
Score = 37.7 bits (86), Expect = 0.045
Identities = 54/216 (25%), Positives = 71/216 (32%), Gaps = 5/216 (2%)
Frame = +3
Query: 225 SVKKSDADNKKIAYDRSSKPSYGYGGSFGVQKDRMDKCAVGNDYVAAVDKHTSQKDYSQG 404
+ K + ++ SK +G S G+ + A + + TS + G
Sbjct: 325 ATKNGFGGDSSSSFGSGSKAGFGGTSSSGIGGQKPG--ATESSGFPTKETSTSGGTFGSG 382
Query: 405 FGGK-----YGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVG 569
FGGK +G S S K G D S GFG KA G
Sbjct: 383 FGGKPTSTGFGAPSTTDSSSGQQTAGFGGASKPGFGGDSSTGFGSGL--------KAGFG 434
Query: 570 WEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGK 749
H+A ++S + GFGGK G+ E QQ SKGFGG
Sbjct: 435 G-HRASTAENSGLPTETTGFGGKL---------PPAGFGASSSNESAFGQQ--SKGFGG- 481
Query: 750 YGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGG 857
K G + GK S GFGG
Sbjct: 482 -------ATKNGFGGDSSNSFGKRDS------GFGG 504
>sp|P34857|NU6M_APILI NADH-ubiquinone oxidoreductase chain 6 (NADH dehydrogenase subunit
6)
Length = 167
Score = 37.0 bits (84), Expect = 0.076
Identities = 25/70 (35%), Positives = 35/70 (50%)
Frame = -1
Query: 560 SFILSIFLNTIFTTKSFRIILLRSMLLNFRLIFPTRCTFILSITLYSIFTPESL*IIFLR 381
S IL+I+LN IF + S +I L S + L+ T C+ + L + I+FL
Sbjct: 18 SMILTIYLNNIFNSPSMLLIYLISYSIYMSLMMFTMCSMNSLLILMIL-------IVFLS 70
Query: 380 GMLINSGYII 351
GMLI Y I
Sbjct: 71 GMLIMFSYFI 80
>sp|Q28092|CYLC2_BOVIN Cylicin-2 (Cylicin II) (Multiple-band polypeptide II)
Length = 488
Score = 36.6 bits (83), Expect = 0.099
Identities = 48/207 (23%), Positives = 87/207 (42%), Gaps = 2/207 (0%)
Frame = +3
Query: 219 KESVKKSDADNKKIAYDRSSKPSYGYGGSFGVQKDRMDKCAVGNDYVAAVDKHTSQKDYS 398
K+ +KK D+KK + G G +KDR + K T S
Sbjct: 158 KKDLKKERKDSKKGKESATESEDEKAGAEKGAKKDRKG---------SKKGKETPSDSGS 208
Query: 399 QGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVGWEH 578
+ K + +KD ++E +K +++D K GK G +K ++
Sbjct: 209 EKGDAKKDSKKSKKDSKGKESATESEGEKGDAKKDDKK---GKKGSKKGKESAT------ 259
Query: 579 KAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKG-FGGKYG 755
++E EK ++KD + GK G +K ++ + + E EK +++D KG G K G
Sbjct: 260 ESEGEKGDAKKDDKK---GKKGSKKGKESAT------ESEGEKGDAKKDDKKGKKGSKKG 310
Query: 756 VQTDRQDKCAVGWEHKEE-LGKHASQQ 833
++ + + G K++ GK S++
Sbjct: 311 KESATESEGEKGDAKKDDKKGKKGSKK 337
Score = 32.7 bits (73), Expect = 1.4
Identities = 45/203 (22%), Positives = 80/203 (39%), Gaps = 1/203 (0%)
Frame = +3
Query: 144 EKEQRWGSKTVSGSGRTDFIDLSALKESVKKSDADNKKIAYDRSSKPSYGYGGSFGVQKD 323
+K+ + G K S G+ + K KK D KK + + G +KD
Sbjct: 241 KKDDKKGKKG-SKKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKKD 299
Query: 324 -RMDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQ 500
+ K +A + + D + K G + +K K +A ++E +K +++
Sbjct: 300 DKKGKKGSKKGKESATESEGEKGDAKKD--DKKGKKGSKKGKESAT---ESEGEKGDAKK 354
Query: 501 DYSKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVG 680
D KG K G +K ++ + KAE +K ++KD +++DK
Sbjct: 355 DDKKG---KKGSKKGKES------DSKAEGDKGDAKKD-------------DKKDKKGSK 392
Query: 681 WEHKEETEKHGSQQDYSKGFGGK 749
+ TE G ++D K GK
Sbjct: 393 KGKESATESEGEKKDSKKDKAGK 415
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,205,235
Number of Sequences: 369166
Number of extensions: 2207037
Number of successful extensions: 6483
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5577
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6397
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9174518830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)